Join us for the next edition of the EMBO | EMBL Symposium 'The complex life of RNA'! 🔬🧬 The programme will include topics on transcription, RNA processing and modification, mRNA export and localisation, mRNA surveillance and decay, and more 💻 s.embl.org/ees26-12-bl

Out now in Science! Our study challenges long-standing assumptions about transcription factor specificity in eukaryotes. Novel single-molecule measurements of TF behavior in living cells reveal an independence of locus-specific binding from DNA sequence recognition.🧵 www.science.org/doi/10.1126/...

ESCRT proteins organise stress-induced organelle contact between endoplasmic reticulum and Golgi https://www.biorxiv.org/content/10.64898/2026.05.29.728859v1

Editor Spotlight: Amy Gladfelter Duke University “MBoC welcomes interdisciplinary work addressing fundamental cell biology, offers a thoughtful review process, and provides space for discussion about our scientific culture.” Explore the journal and submission opportunities at molbiolcell.org

IDPSeminars is back for a final seminar of spring 2026! This week, we welcome Wenwei Zheng and Sigrid Milles! The seminar is at 10 AM PST / 1 pm EST / 7 PM European time on Thursday. Sign up via our website at idpseminars.com!

Final call – One week left! Abstract submission is open until 9 June for The American Society for Cell Biology (ASCB) | EMBO #CellBio2026 meeting in #SanDiego #California, United States, 12–15 December 2026. 🧪 https://www.ascb.org/cellbio2026/#CellBio2026#SanDiego#California#LifeSciences #research #conference #meeting

📚 Textbook rewrite: #Yeast reveals lysosomes get protons directly from mitochondria via membrane contacts, not from cytosol as thought. Aging breaks these contacts, causing de-acidification that disrupts autophagy & cellular function 🧬 #YeastResearch 🧪 #SGD 🔬 www.yeastgenome.org/reference/S1...

Everything you wanted to know about the protein chemistry behind how amino-acid changes affect the cellular abundance of proteins from @tkschulze.bsky.social Effects of residue substitutions on the cellular abundance of proteins doi.org/10.7554/eLif...

Come join our institute as a Full Professor! We are looking for outstanding scientists to join a highly collaborative and internationally recognized research environment in the beautiful city of Heidelberg! @uniheidelberg.bsky.social @sfb1638.bsky.social #TRR186 #TRR319

Heidelberg University Biochemistry Center @bzh-hd.bsky.social is looking for a #professor of #biochemistry. Please spread the word‼️ www.bzh.uni-heidelberg.de

The ZMBH welcomes Dr. James Sáenz @jamessaenz.bsky.social as new Professor in Molecular Biology. James previously led a research group at B CUBE - Center for Molecular Bioengineering of Dresden University of Technology.

We told you it wouldn’t be a long wait. 👀 Even more predicted protein structures have been added to the #AlphaFold Database. This time, the database has expanded to include heterodimers – protein complexes made up of two different proteins. alphafold.ebi.ac.uk

Bacteria don't need signaling cascades to rewire gene silencing. They use DNA 🧬 twist. ➕Overwind → H-NS forms a filament. ➖Underwind → H-NS bridges and silences. 📣Topology is the switch. See our preprint for more details: doi.org/10.64898/202...

www.nature.com/articles/s41... - from @igorulitsky.bsky.social - "most chromatin regions reported as bound by trans-acting RNAs in recent studies in mammalian cells appear to be technical artifacts"

I am deeply honored to have been elected as a Foreign Member of the @royalsociety.org. Very grateful to all members of the lab, past & present. Their curiosity & commitment to science shaped the work in countless ways. It's been a privilege to work with them. www.mpinat.mpg.de/5261989/pr_2...

We enjoyed putting our heads together with the Jakob and Freddolino labs to find that polyphosphate modulates the formation of functional RNA-protein condensates in response to nitrogen-starvation stress! journals.plos.org/plosbiology/...

A new study led by WHOI biologist Francesco Ventura investigated why storm petrels take a slower and more energy-intensive flight across the open ocean. Learn more from @earthdotcom.bsky.social: go.whoi.edu/stormpetrel

Thank you to everyone who joined #EESPhaseSeparation 🧪 Next to discussions spanning condensates in signalling, genome organisation, disease, and the physical principles underlying intracellular phase transitions, we had plenty of opportunities to spark new collaborations, reconnect, and socialise!

🧬Work on #transcription and/or #chromatin? 📙The abstract submission deadline for the EMBL ‘Transcription and chromatin’ conference in Heidelberg, 25-28 Aug 26 is next Tuesday (26th May)! 📝Register online here: www.embl.org/about/info/c... @embl.org @embo.org

The Plant Epigenetics & Stress Adaptation lab at Uni Potsdam are very happy to present our latest review on plant heat stress responses. Here we cover some fascinating new developments in the field, including biomolecular condensates, phenotypic plasticity and epigenetic memory: rdcu.be/fknSe

Could Living Cells Use Phase Transitions to Process Information? By Arvind Murugan @amurugan.bsky.social, David Zwicker @zwickergroup.bsky.social, Charlotta Lorenz and Eric R. Dufresne @softliv.bsky.social. journals.aps.org/prx/abstract...

Our work investigating mRNA 3' UTRs that trigger target-directed miRNA degradation is now published! genesdev.cshlp.org/content/earl...

Protein Disulfide Isomerase (PDI) disassembles TDP-43/G3BP1 condensates and antagonizes TDP-43 aggregates. By Jia-Qi Liu, ..., Mengchao Cui, Yi Liang, et al. advanced.onlinelibrary.wiley.com/doi/10.1002/...

Cooperativity, dynamics, and the free-energy surfaces of charge-patterned IDPs https://www.biorxiv.org/content/10.64898/2026.05.21.726897v1

Did you know tiny algae can "skate" within Arctic sea ice? ⛸️ Our new study in @pnas.org reveals the secret life of ice diatoms: they are actively gliding to navigate the ice! This adds a new dimension to the sea ice ecosystem, revealing an active, dynamic ecological niche. @prakashlab.bsky.social

「エビデンスを出せ！」と言われた際にお使いください

Are you analysing hydrophobicity in disordered proteins and still using the Kyte & Doolittle scale? Maybe instead consider the "stickiness-scale" that Fan & Giulio derived using SAXS data for >100 IDPs doi.org/10.1021/acs....

As it’s #WorldTurtleDay, meet Blandings, an unimaginatively named Blanding’s Turtle Emydoidea blandingii. He came to live with us about 4 years ago, having been imported (legally!) from his native range around the Great Lakes in the 1970s

“Strikingly, native mRNA sequences are markedly less prone to self-association than matched randomized controls…Similar signatures are observed in abundant human mRNAs, suggesting that evolution has shaped coding sequences to minimize self-association.” 🧪

Good morning, from #Heidelberg

Maintaining transcriptome solubility constrains mRNA sequence composition Exploring the propensity for self-association of the transcriptome via RNA–RNA interactions! Amazing preprint by Marco Todisco, Christalyn Ausler and Ankur Jain. www.biorxiv.org/content/10.1...

On Thursday, David McCuan from Sonoma State University will give a talk on "The Mother of All Midterms: The Game-Changing American Elections of 2026" 🕰️ May 28, 6:15 p.m. 📍 HCA, Atrium This event is part of our event series "The Future of US Democracy".

Good morning, # Tübingen

Hip hip hurray - we have a new doctor in the house. Congratulations Dr @cbrannon.bsky.social that was a spectacular defense; so many fun stories all tied together in an hour. Also, the same week Charlotte’s big paper on information bottlenecks in ciliary flocks got accepted in Nature Physics.

Was a very fun week at the @embl.org symposium on phase separation! A nice emerging theme was pH and electrostatic charge. Not much grappling with terms/naming conventions, but it was a safe space for just calling things as you wanted. Here was a nice view towards my colleagues @embopress.org

Hard to believe that 'Cellular mechanisms driven by phase separation' is over! With everyone already on their way back, we can't stop thinking about what a brilliant time we've had over the past 4 days. Safe travels and stay tuned for more info on the poster prize winners! #EESPhaseSeparation 🧪

This week, EMBO Director Fiona Watt and Head of Scientific Affairs Julie Sollier visited institutes and labs in Prague #Czechia and Bratislava #Slovakia. 🧪 Here some impressions: Fiona speaking at BIOCEV Prague and with EMBO Member Silvia Pastoreková at SAS Biomedical Research Center Bratislava.

Met a new friend

We had such a fun ERC Synergy @erc.europa.eu kickoff workshop for our 6-year MitoContact collaborative project with our partners Kai Johnsson and Wanda Kukulski! Wonderful to share science, ideas, and play games together 💚 fantastic organization by @zimmerli.bsky.social @jclandoni.bsky.social

Multinucleate cells challenge deeply-held assumptions about complexity, ecological success and evolution. Postdoc extraordinaire and gifted writer @mrosjac.bsky.social tackles this subject with aplomb - tell us what you think! www.sciencedirect.com/science/arti... @currentbiology.bsky.social

Pardon the language but this threadless shirt made me LOL www.threadless.com/shop/@lousyd...

Day 2 of 'Cellular mechanisms driven by phase separation' going well so far, with the first poster session behind us! 📊🔍 Looking forward to many interesting talks still ahead of us as well as to more time to socialise this evening 💬 #EESPhaseSeparation @embo.org @embl.org

Safe to say that Day 1 of 'Cellular mechanisms driven by phase separation' has been a success so far, with lots of great talks, including a keynote by Karla Neugebauer, and plenty of opportunities to socialise and get to know each other 🙌🏼 #EESPhaseSeparation @embo.org @embl.org

Let's talk #condensates! #EESPhaseSeparation

Two of our lab members are at the EMBO | EMBL Symposium on cellular mechanisms driven by phase separation this week! 🙌 Come and visit their posters: 📌 Mariya → Poster #114 📌 Joachim → Poster #54 #EESPhaseSeparation @events.embl.org @embo.org @embl.org

Here for the week with my cherished colleagues @embopress.org (and some phase separation thanks to the EMBL symposium)

Dr. Arpita Singh @arpitasingh.bsky.social, a National Postdoctoral Fellow in our lab, is attending an EMBO Symposium on "Cellular Mechanisms Driven by Phase Separation" starting today at EMBL Heidelberg, Germany. She will present her new results on nucleolar condensates. www.embl.org/about/info/c...

Determinants of centromeric nucleosome conformation https://www.biorxiv.org/content/10.64898/2026.05.15.724335v1