I am beyond excited to announce that the Bisson Lab has a new home!!! Starting January 2026, I will join the Biology Department at Indiana University Bloomington as Associate Professor with tenure. I am actively recruiting scientists across all levels. More in our website: bissonlab.com/join [1/4]

Now in print: @lortzrodz.bsky.social with @schraderlab.bsky.social found that the stress-induced transition of the material properties of bacterial ribonucleoprotein bodies repurposes them from sites of mRNA decay to reservoirs for mRNA storage. @natcomms.nature.com www.nature.com/articles/s41...

Thrilled to share our multidisiplinary work on how genome-wide DNA bridging by H-NS reshapes the stationary phase bacterial nucleoid and affects the transcriptional landscape. With Xindan Wang and @meyerroc.bsky.social www.biorxiv.org/content/10.1...

Caulophiles take note 👇 #MicroSky

So proud to have trained with Lucy. She is an exceptional scientist, exceptional person, and exceptional mentor. Huge congrats and so well-deserved. laskerfoundation.org/winners/pion...

*** Only a few days left to apply *** Postdoc position at the University of Marburg (Germany), funded within our ERC Advanced Grant "C-SWITCH" Spatiotemporal regulation of cellular processes by CTP-switches in bacteria Apply by 04 May: stellenangebote.uni-marburg.de/jobposting/2...

Interesting study shows CsrA forms a dynamic, membraneless compartment with sRNAs, mRNAs & the degradosome in E. coli, flipping its role between activating and repressing virulence. A new layer of RNA-based regulation! #microbiology #RNA #CsrA www.nature.com/articles/s41...

Registration is open, look forward to seeing you! microbialrnameeting.com

Striking new study from @archaeon-alex.bsky.social's lab just out in @science.org on multicellular development induced by compression in Archaea: www.science.org/doi/10.1126/...

Spread the word to support science communication through illustrated storytelling. And if you want your own copy of this microbial adventure comic, 5 days remain at 20% off. www.lulu.com/shop/james-m...

Our team found the N-terminal IDR of bacterial translation initiation factor 2 promotes condensation with RNA that is stimulated in the cold. We think these cold-stimulated IF2 condensates likely explain why the IDR's deletion in E. coli is unable to grow in the cold. www.biorxiv.org/content/10.1...

1/ 🚨We’re thrilled to share our latest study: "Cellular Function of a Biomolecular Condensate Is Determined by Its Ultrastructure" 🌟 www.biorxiv.org/content/10.1... How do biomolecular condensates achieve their cellular roles? It comes down to their internal structure. 🧵⬇️

One year ago today my lab was destroyed in a fire. Nobody was hurt and our key freezer samples survived. My colleague Tamara Hendrickson has graciously hosted all my trainees in her lab since. In January, the Schrader Lab will be officially reopening at Indiana University.

Thrilled to share Luis' manuscript showing how bacterial ribonucleoprotein bodies (BR-bodies) control RNA metabolism: stress changes the bacterial biomolecular condensate material state *and* shifts function from mRNA decay to storage. #LiveCell #SingleMolecule #Microscopy @schraderlab.bsky.social

We're very excited about the new preprint from @juliebiteenlab.bsky.social and our lab. We found that upon stress, BR-bodies material state becomes more solid/gel-like, changing their activity from mRNA decay to mRNA storage. Check it out here: www.biorxiv.org/content/10.1...

Stress Changes the Bacterial Biomolecular Condensate Material State and Shifts Function from mRNA Decay to Storage https://www.biorxiv.org/content/10.1101/2024.11.12.623272v1

Microbial reaction rate estimation using proteins and proteomes https://www.biorxiv.org/content/10.1101/2024.08.13.607198v1

Formylation facilitates the reduction of oxidized initiator methionines https://www.biorxiv.org/content/10.1101/2024.02.06.579201v1

We have a new story out at BiorXiv! Amazing work led by Zach Curtis (Bisson), Pedro Escudeiro (Alva) and John Mallon (Bisson). Great collaboration with @vikramalva.bsky.social (Max Planck) and Mecky Pohlschroder (UPenn). t.co/qGvuQ7mwO1

Late consolidation of rRNA structure during co-transcriptional assembly in E. coli by time-resolved DMS footprinting https://www.biorxiv.org/content/10.1101/2024.01.10.574868v1

tRNA!