Yves Brun lab
@brunlabcaulo.bsky.social
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We like to look at bacteria do the things they do. Université de Montréal.
pinned post!
Please repost: Postdoc position in antibiotic discovery in a large multidisciplinary project combining high-throughput approaches, microscopy, AI, and hit-to-lead optimization at
@umontreal.ca
and
@mila-quebec.bsky.social
. Apply to
[email protected]
. See
lnkd.in/dVVk4N3s
.
#microsky
7 months ago
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Light reading to distract me from the news. Yet it is strangely familiar.
6 days ago
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Why do we always submit grant proposals at the last minute? This never ceases to amaze me.
2 months ago
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3 months ago
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Please repost: PhD position with my lab and
@weisslab.bsky.social
in a great collaboration on bacterial adhesion
#microsky
. See
drive.google.com/file/d/1GJD4...
3 months ago
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As I was saying, happy to be back home! Cheers!
3 months ago
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Congratulations Marie! Immensely proud! Looking forward to seeing where you take your project on evolution of bacterial elongation.
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3 months ago
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Sabbatical is over! I really enjoyed my time in Marseille for 10 months
@lcbofficiel.bsky.social
but very happy to be back in Montreal and with my lab. Also, the view from my office 😀
3 months ago
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Excited to see our automated HT growth/microscopy screening platform coming together. Pictured: the intermediate version to screen 5-10,000/day unattended. Diagrammed is the full platform due next summer after renovations @ 20,000/day and integrated with our colony picker.
3 months ago
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Yves Brun lab
Marie Delaby
3 months ago
Exciting news! My work with Liu Yang in the
@brunlabcaulo.bsky.social
, “Phenotypic plasticity in cell elongation among closely related bacterial species”, has been selected as an Editors’ Highlight in
@natcomms.nature.com
under Microbiology and infectious diseases! Check it out here:
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Editors' Highlights | Nature Communications
Editors' Highlights
https://www.nature.com/ncomms/editorshighlights
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How does your favorite species elongate? 🧵 "Phenotypic plasticity in bacterial elongation among closely related species". Happy to see this paper in print
@natcomms.nature.com
. Nice work by
@mariedelaby.bsky.social
, Liu Yang et al. See original 🧵, different colours, same data and conclusions.
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4 months ago
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Excited to be in Grenoble surrounded by mountains to give a seminar today at the IBS where I was on sabbatical 10 years ago.
4 months ago
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Yves Brun lab
Sebastian S. Cocioba
5 months ago
I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs. Plant, Bacterial, Archaeal Non-model Bioeng Custom Lab Hardware Turn Key Genetic Design Please repost for reach 💚
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5 months ago
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Indeed, please also check the paper on the same topic by
@lowlab.bsky.social
published a few months ago in the same journal.
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5 months ago
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Great to see
@ianyyen.bsky.social
's first paper in print! He deserves major congratulations for driving a stimulating collaboration: he determined structures of the Tad pilus ATPase CpaF from Caulobacter and proposes how CpaF employs a rotary mechanism of catalysis to drive pilus assembly
#microsky
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5 months ago
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Yves Brun lab
Paul Francois
5 months ago
This is why the new threat against university funding in Canada is concerning, clearly a fraction of the population here do not understand either how things work and universities contribute.
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Yves Brun lab
Anthony Vecchiarelli
6 months ago
New paper from the Vecchiarelli Lab! 🧵
pubs.acs.org/doi/10.1021/...
In collaboration with Lu-Ning Liu lab. Congratulations to first author Claudia Mak!
@claudiamak.bsky.social
P.S. Claudia is looking for postdocs in protein biochemistry! Pls ReSkeet
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Carboxysome Shell Protein CcmK2 Assembles into Monodisperse and pH-Reversible Microparticles
Synthetic nano- and microparticles have become essential tools in biotechnology. Protein-based compartments offer distinct advantages over synthetic particles, such as biodegradability and biocompatib...
https://pubs.acs.org/doi/10.1021/acsnano.4c18021
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Yves Brun lab
Mark Peifer (He, him)
6 months ago
>1900 members of the National Academies of Science, Engineering & Medicine issued a statement supporting science for the benefit of all citizens, and ... 1/2
docs.google.com/document/d/1...
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Public Statement on Supporting Science for the Benefit of All Citizens
TO THE AMERICAN PEOPLE We all rely on science. Science gave us the smartphones in our pockets, the navigation systems in our cars, and life-saving medical care. We count on engineers when we drive acr...
https://docs.google.com/document/d/13gmMJOMsoNKC4U-A8rhJrzu_xhgS51PEfNMPG9Q_cmE/preview?tab=t.0
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Yves Brun lab
Clara Jeffery
6 months ago
1/ On April 5, there are nationwide protests happening literally everywhere in the US. Find more details here:
handsoff2025.com
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Yves Brun lab
Ian Henderson
6 months ago
I am walking 800km of the Camino de Santiago to raise funds for cardiovascular research—the world’s largest killer! ❤️🩹 This journey is not just a personal adventure, but a mission to make a real difference in fighting heart disease. Check out the link to learn more
www.justgiving.com/campaign/cam...
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Camino for a cause – Prof. Ian Henderson’s journey to fund IMB cardiovascular research
Professor Ian Henderson, Director of the Institute for Molecular Bioscience, is taking on the epic Camino Francés, a nearly 800km trek through rural Spain. With each step, Ian will raise vital funds t...
https://www.justgiving.com/campaign/camino-for-a-cause
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Yves Brun lab
Jeremy Berg
6 months ago
Funding curves for K and F mechanisms (Warning: the new F mechanism "curve" is a lot)
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Yves Brun lab
Vaughn Cooper
6 months ago
Terrific set of perspectives and opinions by several researchers, including me, on how to process and respond to attacks on US science specifically, and science writ large.
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Yves Brun lab
Tera Levin
6 months ago
💐 To NIH and NSF program officers, and anyone else trying to keep those institutions alive: Thank you for trying to do an impossible job in an impossible time. I’m sorry for all of us that this is the world we’re living in. 1/n
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Yves Brun lab
Gerry Wright
6 months ago
The latest discovery from the lab and great colleagues at McMaster and U Illinois, Chicago. Lariocidin, a new lasso peptide antibiotic that inhibits the ribosome.
rdcu.be/efdha
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A broad-spectrum lasso peptide antibiotic targeting the bacterial ribosome
Nature - A new lasso peptide antibiotic exhibits broad-spectrum activity against Gram-negative and Gram-positive bacteria by interfering with bacterial protein synthesis, is unaffected by common...
https://rdcu.be/efdha
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Yves Brun lab
Dr Katherine Duncan
6 months ago
New antibiotic that kills drug-resistant bacteria discovered in technician’s garden
www.nature.com/articles/d41...
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New antibiotic that kills drug-resistant bacteria discovered in technician’s garden
The molecule targets bacteria in a way that other drugs don’t.
https://www.nature.com/articles/d41586-025-00945-z
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Yves Brun lab
STCmicrobeblog
6 months ago
we really hope that the organizers of meetings/conferences in the US will quickly come back to offering hybrid meetings as we had during the pandemic to allow attendance of non-US researchers.
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Some friends who have permanent residency in the US just told us they now have an emergency plan. I assume this is probably necessary for anyone who was not born in the US. Probably also for people born there but with the wrong allegiance… Scary!
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6 months ago
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Sad to have to cancel my participation as a speaker at the Bacterial Cell Biology Gordon Conference, but the current situation in the US does not give one much of a choice.
6 months ago
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I guess I am not going to the US for a while! They might find some slightly critical comments on my devices…
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6 months ago
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Please repost: Postdoc position in antibiotic discovery in a large multidisciplinary project combining high-throughput approaches, microscopy, AI, and hit-to-lead optimization at
@umontreal.ca
and
@mila-quebec.bsky.social
. Apply to
[email protected]
. See
lnkd.in/dVVk4N3s
.
#microsky
7 months ago
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reposted by
Yves Brun lab
Vaughn Cooper
7 months ago
My talking points in recent interviews, please use as you see fit: 1.Every $1 in NIH funding returns ~$2.50 to the economy. 2.Every $1B in cuts from NIH extramural = 7500 lost employees, just in science. 3.These don't include priceless improvements in health. 1/x
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Read this.
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7 months ago
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Yves Brun lab
Scott Delaney
7 months ago
NIH indirects case update: Hearing ongoing now, and I'll try to live tweet some notable exchanges. Prior to more detailed arguments, Judge Kelley starts off with a few point questions to both sides: (I'm paraphrasing here)
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What he said!
7 months ago
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Fixed it.
#microsky
7 months ago
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1/10 🧵 Injecting some science in your feed: Happy to share another chapter in our investigation of bacterial surface sensing. We describe the role of CpaL, a minor pilin-like protein, a key player in surface sensing and adhesion in Caulobacter crescentus.
#microsky
www.biorxiv.org/content/10.1...
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Stimulation of the Caulobacter crescentus surface sensing pathway by deletion of a specialized minor pilin-like gene
Bacteria colonize surfaces through complex mechanisms of surface sensing. Pili are dynamic bacterial appendages that play an important role in this process. In Caulobacter crescentus , tension on retr...
https://www.biorxiv.org/content/10.1101/2025.02.12.637803v1
7 months ago
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@baym.lol
has an excellent point. Will try to do things this afternoon.
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7 months ago
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Just reposting this because it quickly got buried by everything happening in the US.
add a skeleton here at some point
7 months ago
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Yves Brun lab
Chrystal Starbird
7 months ago
An initiative led by brave graduate students and leaders to fight for science!
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Gotta love autocorrect! “CryoEM” although CryingEM might be appropriate currently.
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7 months ago
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Congrats Erin
@goleylab.bsky.social
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7 months ago
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Crying-EM Faculty position! Montreal is indeed a fantastic place to live and work. Even more so now by comparison…
add a skeleton here at some point
7 months ago
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Yves Brun lab
Alex Hernandez-Garcia
7 months ago
🚨 Call for a POSTDOC in machine learning for drug discovery at
@umontreal.ca
💊 This is a large collaboration with
@brunlabcaulo.bsky.social
@audurand.bsky.social
@dom-beaini.bsky.social
Anne Marinier
@mila-quebec.bsky.social
IRIC All details here:
brunlab.com/jobs/open-po...
Please repost 💜
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Postdoctoral Researcher – Brun Lab
https://brunlab.com/jobs/open-positions/postdoc/
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Please repost: Postdoc position in AI for drug discovery in a large collaboration with Dominique Beaini, Audrey Durand, Alex Hernández-García, Anne Marinier at Université de Montréal and Montreal Institute for Learning Algorithms (MILA).
www.linkedin.com/posts/yves-b...
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Yves Brun on LinkedIn: Postdoc position in AI for drug discovery in a large collaboration with…
Postdoc position in AI for drug discovery in a large collaboration with Dominique Beaini, Audrey Durand, Alex Hernández-García, Anne Marinier at Université de…
https://www.linkedin.com/posts/yves-brun-829631163_postdoc-position-in-ai-for-drug-discovery-activity-7295007512452358144-gpQ0?utm_source=share&utm_medium=member_desktop
8 months ago
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Yves Brun lab
Dr Kathleen Millen
8 months ago
I truly long for the days when we all got really upset because
#NIH
changed Biosketch formats. Ah, the good old days.
#AcademicSky
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9 months ago
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Yves Brun lab
Prachee Avasthi
9 months ago
Hot off the presses today is the 2024 NIH Public Access Policy. I read it so you don’t have t…Just kidding. You should still read it in full if you do NIH funded research.
grants.nih.gov/grants/guide...
Some highlights in the thread below
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NOT-OD-25-047: 2024 NIH Public Access Policy
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: 2024 NIH Public Access Policy NOT-OD-25-047. OD
https://grants.nih.gov/grants/guide/notice-files/NOT-OD-25-047.html
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Here for a seminar this afternoon.
10 months ago
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Now with beer. Unfortunately no Guinness. This beer is what they call an “easy drinking IPA”, which based on the taste must mean “not much flavor”…
add a skeleton here at some point
10 months ago
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