Now published in @cp-cellsystems.bsky.social - we look at the chemical features that make proteins tolerant to dehydration, and the functions these proteins fill. 🏜️🚱 tinyurl.com/bsfy56yt

All wiggly protein afficionados 🍝 - The IDP grodon conf is filling up fast. Please submit your registration ASAP! The conference takes place June 21-27 2026 in Les Diablerets, Switzerland, with an amazing speaker lineup! Details: tinyurl.com/yfm5jsxt @idpgrc.bsky.social @idpseminars.bsky.social

So happy to announce our new preprint, “A geothermal amoeba sets a new upper temperature limit for eukaryotes.” We cultured a novel amoeba from Lassen Volcanic NP (CA, USA) that divides at 63°C (145°F) 🔥 - a new record for euk growth! #protistsonsky 🧵

🧬Next up: Mustafa Mir in the Transcription and Chromatin Regulation session! His lab uses live embryo & single-cell single-molecule tracking to reveal how IDRs guide transcription factor target search & specificity - shedding light on gene regulation in development. @mirlab.bsky.social

The First Annual Virtual WALII Symposium: Exploring Life Without Water is ONE WEEK AWAY! 🗓️💧 Register now to join us on November, 18! www.walii.science/virtual-symp...

🚨🚨The GRC on Intrinsically Disordered Proteins #IDPs is back!! 🍝🧵🏔️Join us for cutting-edge IDP science, great discussions, and mountain views 🌄🍝 📅 June 21-26, 2026 | Les Diablerets, Switzerland 👉 Details & registration: grc.org/intrinsicall...

🚨The 2026 IDP GRC Program is LIVE! 📣 Check it out: www.grc.org/intrinsicall... We’ve got an incredible speaker lineup! 🌟 Over the next few weeks, we’ll be highlighting some of them and giving you a sneak peek at the exciting topics they’ll be covering. Stay tuned!

🎉Excited to announce that Dr. Rebecca Berlow @berlowlab.bsky.social will speak in the “Disorder in Pathogens” session at #IDPGRC2026! The Berlow lab uses solution NMR and biophysical approaches to uncover how IDP sequence, dynamics & function drive transcriptional regulation.

🖥️Next up: Jeetain Mittal in the Material Properties of IDPs and Condensates session! His team uses multiscale simulations to uncover how sequence-encoded interactions in IDPs govern conformational transitions & condensate behavior - informing neurodegenerative research. @mittalgrouptamu.bsky.social

📢 Abstract deadline Nov 1! Join us at the FASEB Conference on Biomolecular Phase Transitions (Jan 11–15, 2026, Melbourne, FL), showcasing cutting-edge research on condensates in health & disease, and therapeutic frontiers. ~30% talks from abstracts! events.faseb.org/event/480194...

Thanks @elevylab.bsky.social for a fantastic writeup!!

Can't wait to see you all there!!

The power of collaborations! With @shaharsu.bsky.social, his PD @jessniblo.bsky.social and CALVADOS3 (thanks to @lindorfflarsen.bsky.social ) we show how STI1 (red) may engage with sequences that match transient helices within IDRs of Ub-binding shuttle protein Dsk2 www.biorxiv.org/content/10.1...

Announcing the joint @idpseminars.bsky.social / BPS IDP Subgroup Trainee Symposium Speakers! Join us on Mar 27, 12–2pm CST for 6 exciting talks focused on Intrinsically Disordered Proteins as part of #BophysicsWeek2025 with the @biophysicalsoc.bsky.social Sign up now using the QR code below!

📢 Excited to share our research with @shaharsu.bsky.social & @mvstaller.bsky.social on how activation domain (AD) structure affects gene expression! 🧬 TLDR: HIF-1α & CITED2 ADs suggest ensemble dimensions may regulate transcription in unique ways. www.cell.com/biophysrepor... 🧵 Highlights:

Excited to announce the newest member of the flock - STARLING (conSTruction of intrinsicAlly disoRdered proteins ensembles efficientLy vIa multi-dimeNsional Generative models). www.biorxiv.org/content/10.1...

The STARLING has landed - excited to share new work from @bornanovak.bsky.social and @jefflotthammer.bsky.social in what is also Borna's first Bluesky post! If you're at BPS, I'll be speaking about this this afternoon in IDP SG, and Borna and Jeff both have posters (Sunday B112 and Wed B152).

Announcing the Biophysics Week IDP Trainee Symposium on March 27 at 12pm CT hosted by @idpseminars.bsky.social & The BPS IDP Subgroup! Join via Zoom for talks by talented grad students & postdocs. Abstract submissions are open! See flyer for more details! #BiophysicsWeek @biophysicalsoc.bsky.social

🎉🧪New perspective paper! Single-point missense mutations are common in disordered regions but are often overlooked👀. We analyzed thousands of IDR point mutations associated with human congenital diseases to show that many can significantly change local IDR ensemble structure! shorturl.at/iIbLX

We're back for 2025! This week we welcome Adam Klosin and Randal Halfmann for the first IDPSeminar of Season 17!

New collaborative work in collaboration with the labs of Robert Best & Tanja Mittag driven by Ben Schuler. Identifying Sequence Effects on Chain Dimensions of Disordered Proteins by Integrating Experiments and Simulations. pubs.acs.org/doi/10.1021/...

Last chance to submit your abstract (deadline Tuesday, Feb 20!) for posters & talks for the upcoming EMBO/EMBL Symposium "Cellular mechanisms driven by phase separation", taking place May 14-17 2024 in Heidelberg www.embl.org/about/info/c...

🎉Finally out! Our paper shows that intramolecular interactions in disordered proteins 🍝 can be strong enough to hold inside the cell. 2 years in the making and a labor of love of many people, including @alexholehouse.bsky.social. rdcu.be/du9TY

Today presenting alongside Benedetta Bolognesi in the Condensate Colloquium Series. Not on Bluesky yet, so must shamelessly self-promote, see yours later :-) Also, repost appreciated 🙏

A labor of love - our review on why IDRs matter for cellular function is live in Nat. Rev. Mol. Cell. Biol: www.nature.com/articles/s41... Working with Birthe Kraglund on this was such a pleasure, and we hope this review will be helpful to a broad audience!