New preprint by our predoc Aaron Gadzekpo "Bayesian optimisation and graph-based rheology enable sequence-dependent modelling of DNA materials" Coarse-graining realistic DNA nanostars provides hydrogel network connectivity and mechanics www.biorxiv.org/content/10.6... @centersyngen.bsky.social

Dear #plantscience friends, we're looking to recruit a new colleague at @uni-freiburg.de @biologyunifreiburg.bsky.social: a Professor in Plant Biotechnology. 🌱🧪 The @dompsfr.bsky.social community is truly fantastic. Interested? Please share far and wide and join us! uni-freiburg.de/en/job/00005...

Interesting point, find my opinion below the original post ;-)

There seem to be a lot of terrible revelations about ThermoFisher antibodies. Are we talking about big supplier DNA oligos yet? Had a few eye-opening experiences since starting our lab…

May the sun shine on all labs as it did on Modic and our Hilbert lab groups during our joint outing today 🌞 The photo reminds me how much we grew recently, we were even still missing several members! Most of all, the man Miha @paraspeckle.bsky.social himself, but we ate a lot of 🍕 for you.

Arriving a day late for @events.embl.org #EESPhaseSeparation But today you can already meet Aaron Gadzekpo, Mona Wellhäusser @mofrawe.bsky.social & Elly Lohrer from our group. We present several topics: nanostar simulation, signaling condensates, nuclear actin meshworks, and synthetic chromatin 😁

Got great news on a manuscript this week, extensive and long-term developed story forthcoming soon, ultimately placed in a wonderful journal. Cannot be specific, but also cannot contain myself. So here’s a weird non-factory image I generated with chatGPT, with no relation to the project at all ;-)

Completed the annual Karlsruhe running event “Badische Meile”, shaved 5 minutes off my time from last year (run distance 8,888 km). This year, @kit.edu provided shirts for participating employees and students, I’ve seen *many* green shirts in the crowd. Reminder of the role we play in this city!

Are you looking for a new challenge? We are looking for a Deep Learning Engineer. With this role you would set up deep learning infrastructures with the goal to understand genomes 🧬 and ageing 👵 .

Selected photos from Boys Day last Thursday. We welcomed 7 young bright minds to our lab. They learned about options to study biology, train as lab technicians, and connections with physics, maths, materials and computer science. Offered by Iliya Stoev and our Hilbert Lab members via Center SynGen.

Astra mortemque praestare gradatim

1/5 🤔 What can you actually do with #FLUCS? 💡 FLUCS enables researchers to actively & flexibly control intracellular flows. Non-invasively & label-free. 📩 Get in contact with us to explore how FLUCS can add a new dimension to your research. #Photomanipulation #Bioimaging #Biophysics

Keep on hating AI, but the new Copilot in MatLab just *explained an error*: structured, accurate, complete with troubleshooting and fix-walk-through, pertaining to a *MatLab-external library". It actually teaches! Chapeau @mathworks.bsky.social! Of course, hat tip to @openmicroscopy.org

Very interesting new preprint from Patrick Murphy's group @pjmurphy249.bsky.social, finding that intergenic Pol II binding before zygotic genome activation is connected to repetitive element transcription. www.researchsquare.com/article/rs-9...

Received this nice Easter present for our lab today. Happy Easter and good luck to all colleagues and collaborators :-) 🥚🐟🧬

Some work life impressions of the week: Huge-a&& KIT logo downtown, our new slogan #scienceforimpact (I like it) Friday evening Campus North institute sunset panorama Drosophila testes imaging for revisions with @erhardtlab.bsky.social lab, samples looking great! #FluorescenceFriday #latergram

We are excited to be recruiting into 3 Associate Professorship's in @oxfordbiochemistry.bsky.social. Come join us as a colleague and benefit from our vibrant and multidisciplinary environment. Reach out to me if you have any questions. Please repost! (tinyurl.com/48deybuu) (tinyurl.com/4pdvjaft).

The online viewer? 👌 Here’s lft1 and lft2 at 50% epiboly, looks great! Too bad dome or sphere isn’t available…

For #FluorescenceFriday, I am sharing a first glimpse at Mona Wellhäusser's @mofrawe.bsky.social new nuclei expansion microscopy. Stained are bulk protein, bulk DNA, and nuclear pore complexes (NPC). Expansion is supposed to be 16x, in all three dimensions. Imaged with @visitech.bsky.social iSIM.

Da haben wir es doch nochmal geschafft, @kit.edu weiterhin Exzellenzuniversität, in guter Nachbarschaft 👋 @uniheidelberg.bsky.social

Arrived at @nvastenhouw.bsky.social lab today for a short visit. I had to stop on my approach to Génopode building @unil.bsky.social and take a photo. This just isn’t fair! 😠

For anyone at @dpgphysik.bsky.social Condensed Matter Spring Meeting: Our PhD student Aaron Gadzekpo is presenting Wednesday morning on one of the major recent areas of work in our group: “Multiscale Approaches to Phase Behaviour and Mechanical Properties of Synthetic DNA Networks”

Our Lab is searching a postdoc for an exciting ERC-funded project that will start this summer. Apply if you’re passionate about multi-omics, cutting-edge computational approaches, and exploring biological questions across the animal 🪼 🪱 🐞 🦎 🦋 🕷️ tree of life www.biozentrum.unibas.ch/open-positio...

Passionate about transcription? 🚀 We’re recruiting a PhD student in Transcriptional Regulation at @ucph.bsky.social Start Summer 2026 Work with RNA, CRISPR, sequencing & proteomics in the Gregersen Lab @cgen2025.bsky.social Meet us: gregersenlab.com Apply by Apr 10, 2026👇 tinyurl.com/PhD-CGEN

Over on threads someone just use ai;dr and we all need to adopt that right quick

Tread -1- EpiSci - I am very proud to share with you our new study that you can access on @biorxivpreprint.bsky.social (see link below) "The Interaction with Nanotopographical Environment regulates nuclear mechanoresponse in mESCs via Histone Demethylase KDM3A. www.biorxiv.org/content/10.6...

Exciting Postdoc Opportunities – Alliance Interinstitutional Program **Deadline:** March 31, 2026 (5:00 pm CEST) 🔗 Two shared positions: www.syn-gen.de/alliance-pos... 🔗 Full call & application info:: www.health-life-sciences.de/opportunitie...

📢Job alert📢 @uniheidelberg.bsky.social has an opening for a full W3-position on “Modeling of Biological Processes” 😀👍 Here is the call tinyurl.com/3w9e9dtf and application deadline is March 15. The group would be located at the beautiful #BioQuant center right in the middle of Neuenheimer Feld.

Monday: new Postdoc arrives at the lab Friday: first own experiment, DNA nanostar condensates clearly visible, even in in vitro transcription buffer Welcome on board, Dr. Marcel Piepers! Stay tuned! PS Marcel is co-supervised w Ralf Reussner, tasked w ground work for www.sfb1608.kit.edu @kit.edu

Apparently, we made the (additional) cover of the January issue of Annals of the NY Academy of Sciences with our artistic representation of surface condensates on a chromatin strand. I hope you appreciate the subtle use of a modified Hilbert curve? nyaspubs.onlinelibrary.wiley.com/doi/10.1111/...

Super feature zu Regenerationsforschung Bei SWR Kultur gehört: Körperteile nachwachsen lassen – Was die Medizin von Tieren lernt - Forschung www.swr2.app/s/koerpertei...

www.wur.nl/en/vacancy/f... Become our new colleague (and next door neighbor) and lead a chair/group/department of Biophysics at Wageningen University. Reach out to me for info and please spread!!!

I am recruiting postdoctoral fellows to develop new research directions in the lab. We study transcriptional regulation through biomolecular condensates in development and disease, with an emphasis on first-principles and mechanistic discovery. Please repost or share with colleagues.

All key information about the German Fish Meeting at COS, Heidelberg (16–18 September 2026) is summarized in this flyer. Please feel free to share it with colleagues and researchers working with any fish model. Thank you!

Progressing well with this year’s Master course Methods of Developmental Genetics, got the first immunostained zebrafish animal caps on the microscope today, nuclear pores looking great, participants in good spirits ✌️ Greetings to all fish labs 🎏

Journals explaining why it takes 9 months to send back reviews

Click bait from yesterday’s safety introduction for 2026 Masters course “Methods if Developmental Genetics” Here my text to go along This is your hand This is your leg This is your foot Just let it fall To the floor First three: one drop into the kiwi Last one: tweezers upright in the floor

There is a special Current Opinion in Genetics & Development issue about genome architecture and expression and it looks great including reviews by @lennarthilbert.bsky.social @yghavi.bsky.social and @wbickmor.bsky.social www.sciencedirect.com/special-issu...

Our Mini Review went online last night in Current Opinion in Genetics & Development "Block copolymer concepts of how transcription organizes the stem cell genome" doi.org/10.1016/j.gd... Fig. 1: Stem cell–typical organization of the genome and transcription, and the block copolymer sorting concept.

I am sure this will be a great presentation by David @zwickergroup.bsky.social He has an excellent (theoretical) biophysics overview of our field! 21 January, 3 PM CET

Wer schon einmal den Gebetsruf oder den Klang spielender Kinder gehört hat, wird den Kontrast mit Explosionen, Raketeneinschlägen und berstenden Scheiben vermutlich genauso unerträglich wie ich finden. Eine erschütternde 50-minütige Klangdokumentation, von heute im SWR. www.swr.de/kultur/gesel...

I am looking for two postdocs to join our lab - One (bio)image analyst - One cell biologist interested to work on lymphatics! The positions will open soon, be in touch!

Apply for a PhD in Singapore at NUS! Deadline Jan 12. I'm recruiting: Here with Mechanobiology Institute: www.mbi.nus.edu.sg/education/gr... and Here with Biomedical Engineering dept: cde.nus.edu.sg/bme/

Great post to start the new year, the first hours of a new life :-) Also tagging @mofrawe.bsky.social here, her handle is a tad difficult to find, but worth to watch and follow ;-)

We are looking for a Postdoc at the Center for Gene Expression in Copenhagen. Deadline for applications is the 11th of January. If you are interested in 3D chromatin, SMC complexes, and super-resolution microscopy, join us. www.nature.com/naturecareer...

Apply soon: Full professorship in Systems #Neuroscience @uni-muenster.de See shorturl.at/VczFp

Some really cool research in this center, should be a nice role to fill :-)

Excellent @activemotifusa.bsky.social epigenetics podcast w @andersshansen.bsky.social It’s interesting, while going through specific projects and lines of questioning, the conversation acts as a nice reflection of the state of our field (fields?) Lots of ideas! open.spotify.com/episode/19Nd...

One more paper made it over the finish line before end of the year, though publication as part of a special issue will be in 2026. Thanks for helpful input from our editor, anonymous peers & colleagues we asked for presubmission feedback, made the piece so much better. 👏 @yuzhibao.bsky.social

Nuclear speckle associated RRM-containing proteins are block copolymers. They make size-limited, ordered microphases, tens of nm in size comprising tens of molecules. Speckles are likely clusters or emulsions of distinct microphases and not macrophases www.sciencedirect.com/science/arti...