I think the rapture happened ages ago and David Bowie was the only one taken. The rest of us are in hell.

it's so nice to see what a functioning judiciary looks like "A transgender woman in the East African nation of Kenya has won a landmark court victory in which the judge not only found in her favour, but ordered the government to pass a Transgender Protection Rights Act." fuck yeah

🎉Check out our new preprint!! 🧬We found that lamin mutations in muscular dystrophy don’t just affect the nucleus — they disrupt a nucleolar–ribosomal axis that reorganizes the entire cytoplasm. Very grateful to @danstarrucdavis.bsky.social, @gwgl.bsky.social and our lab for collaboration & support!

I'd work in a dept. with Joanne as Chair in a flat second. Great department, great people. Apply.

In a UN speech today, President Trump said that "all of these [climate] predictions were wrong". Back in 2019 I led a research effort to digitize old climate model projections and assess how well they did. Turns out they got future warming pretty spot on!

🎙️JOB ANNOUNCEMENT! I am seeking a scientist to design, implement, support, analyze, and report on research in the molecular biology of insect endosymbionts. Come join us in the tips of the Appalachian mountains for meaningful challenges in symbiosis science. psu.wd1.myworkdayjobs.com/PSU_Staff/jo...

🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x

I am begging all news reporters who cover the "tylenol and vaccines cause autism" press conference PLEASE lead your reporting and headlines with facts and caveat that these assertions were not backed by any scientific evidence but rather the whims and feelings on unqualified non-scientists

Reminder that high fever in early pregnancy is really bad. Spread the word, take the Tylenol. (Or Paracetamol!)

let me share a little story about a remarkable wasp that I encountered yesterday in our local deserts I stumbled across her, and scrambled to get a few crappy photos .... but then realized that she had a burrow, perhaps a better photo op was possible ?? here she is at her burrow entrance.

Everyone in academia should read this piece about our dear, brilliant colleague @durba.bsky.social www.thecrimson.com/article/2025...

Dolbear's law: to get the temperature, count the number of chirps a cricket makes in 15 seconds and add 40. #ScienceIsAwesome

Field notes from a weekend PI at the #microscope: vesicle cargo lanes lighting up in real time like @FedEx. This is the ML1N PX domain in a fibroblast. Hot damn, there’s mind-blowing action under the surface of cells: this video shows 2 min of time 🤯 #Cellbio #MicroscopyMonday #SciArt #SciComm

At this exact time and date — 14:19 Eastern US time on September 22, 2025 — the center of the Sun is directly over Earth's equator (in technical terms, it has a declination of 0°), marking the moment of the September equinox. Happy equinox!

🚀 Our new paper is out @natmethods.nature.com! Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells. 🔗 www.nature.com/articles/s41... 🧬 www.addgene.org/John_Ngo/

How many PhDs does it take...

🧵 I've been meaning to write a #Skytorial on our recently posted prepring in which we show evidence that the Golgi 🥞 is a mechanoresponsive organelle. Extracellular mechanical forces also tune Golgi export capacity! 👉 www.biorxiv.org/content/10.1...

Look at that! 🤩 It reminds me of Lantana camara, one of many plants that change color upon pollination: bc it’s easier for bees to see yellows than reds, yellow are young unpollinated flowers, red ones are older and pollination triggered production of more anthocyanin. #plantjoy #iamabotanist 🧪🌿🌸

we found that nuclear envelope rupture triggers rapid DIAPH3 formin influx to generate a actin mesh to prevent further chromatin leakage from damaged nuclei. thanks to Pitter Huesgen @degradomics.bsky.social and @cibss.bsky.social, @chrkam.bsky.social

You know, you've can live someplace a long time and still not totally get the culture. Apparently just signing off with an unmodified "Regards" means you're cross? Sorry everyone in the UK is have inadvertently offended over the years. I am just a clueless Yank.

Ever wondered how to control stretch/compression in your epithelial system? Do you know why it’s important, which mechanotransduction mechanisms could be involved? I am @valeriaventurini.bsky.social and today I will guide you through this journey.

Michael Hobbes vs Jorts

The plan for NSF is to demote its director to an advisory role to what a former senior figure compared to a Soviet political commissar. Also, greatly reduce the role of rotators from academic departments to consolidate administration power. This is a disaster for science and innovation.

The Garnett Lab is excited to launch DepMap Miner, a new tool to explore cancer dependency data! Built on the Sanger DepMap, the DepMap Miner brings together multi-omic and functional datasets for over 1300 cancer cell models. Start mining data now: dataminer.depmap.sanger.ac.uk

Critical part of the President's new $100,000 charge for H1-B visas: The Administration can also offer a $100,000 discount to any person, company, or industry that it wants. Replacing rules with arbitrary discretion. Want visas? You know who to call and who to flatter.

"More professors in the United States have been fired for controversial views in the past week than any other week in all of American history." www.insidehighered.com/opinion/colu...

I know a fae trap when I see one

I gave a talk at Blender Conference yesterday, showing how biological volumes work, and how to visualize them in Blender 😋 youtu.be/WPajSWX730o?... #bcon25

Thank you @jcellsci.bsky.social for this research highlight "Microtubules help macrophages navigate the epidermal maze" as a companion to our manuscript from @errricpeterman.bsky.social ! journals.biologists.com/jcs/article/...

Congrats to my friends in the Boettiger lab for this really beautiful live imaging work. A big leap forward in understanding the dynamic side of genome organization. www.science.org/doi/10.1126/...

Indeed. Earlier this summer, the White House did this to me, as a scientific expert source in media, and issued a formal statement regarding my personal campaign contribution history in an attempt to discredit my commentary on wildfire, climate, and federal policy. Yet more alarm bells ringing...

Give your Disney money to PBS

New preprint alert! The uterus expands ~500-fold in pregnancy, yet we know little about how pressures are sensed. Led by @yunxiao-dr.bsky.social, we show PIEZOs are required for contractions and birth in mice, with dual roles of PIEZO1 in muscle and PIEZO2 in neurons www.biorxiv.org/content/10.1...

Oh. My. God. Profoundly twisted framing from @nytimes.com The casual reader of this hed and subhed would have exactly zero inkling that this is likely corrupt or even illegal or unconstitutional. Euphemistic to the point of absurdity.

@mariasecrier.bsky.social & I are looking for an enthusiastic & excellent data scientist for a 4-year postdoc to understand cell cycle dysregulation in cancer. Deadline 15th October. Get in touch if you have any questions. Please repost! More details: www.imperial.ac.uk/jobs/search-...

We are hiring! We are looking for a PDRA to study the epigenetics of breast cancer dormancy using chemical biology and genomics approaches. This is a 3-year position and is aimed at chemical biologists or biologists. Please share and apply using the link below 👇👇👇 www.imperial.ac.uk/jobs/search-...

IT'S OFFICIAL: Connecticut, Maine, Massachusetts, New Jersey, New York State, Pennsylvania, Rhode Island and New York City have formed the Northeast Public Health Collaborative. The collaborative will issue their own vaccine recommendations and coordinate public health efforts.

Another preprint highlight was posted by Kanishka Parashar! Read how paclitaxel can target cancer cells by destabilising nuclear integrity in interphase - #preprint from @matteoall.bsky.social & team #preprint #preLight ⬇️👀 prelights.biologists.com/highlights/p...

I was on vacation when this one went live - relatively new in @science.org Epithelial tension controls intestinal cell extrusion | Science www.science.org/doi/10.1126/...

Sad I can't attend in person due to teaching duties, but there is an online option!

Curious about new developments in imaging methods? This @embl.org symposium will explore topics on tissue and intravital imaging, AI, image data and modelling, new applications of imaging technologies, and more. Virtual registration is open until October 1. Learn more at plos.io/472r0YR

SCHEPHERD--the bioelectric cell herding platform built for YOU. Single cells, monolayers, organoids--this herds them all + new tricks. Plz try it-- we will *give* you parts! Teaser here of a steering a single cell. GS Yubin Lin's lifeblood with J. Yodh on piano; Celeste R. and Paul K. Thread 1/N

Thrilled to share the first story from my postdoc! 🎉 A wonderful experiment + simulations collaboration. In the Drosophila wing, we find that 3D cell shapes affect signalling range and fine-tune developmental patterning www.biorxiv.org/content/10.1... Thread below ⬇️

So this is the compromise position between sitting on my keyboard and being locked out of the office.

I want you to read one of my 2022 investigations again + understand that the response you’re seeing from your children’s school boards-the harassment + firing of teachers, administrators & staff-is tied to a network of folks who have been in this game for years: www.propublica.org/article/geor...

Mäntylä, E., & Ihalainen, T. O. (2021). Brick Strex: a robust device built of LEGO bricks for mechanical manipulation of cells. Scientific Reports, #EpithelialMechanics www.nature.com/articles/s41...

it's so funny to see America's health insurance companies be like "look. If there's one thing we love it's denying you care. but we ran the numbers - and we cannot BELIEVE we're saying this - and it's cheaper for us to just pay for the vaccines than deal with you going to the ER."

Campaign group Led By Donkeys beams a video with images of US President Donald Trump and convicted sex offender Jeffrey Epstein onto a tower at Windsor Castle. Trump is due in Windsor outside London on 17 September

Science: only when you write up the manuscript, you realize what you should have done.