I hope that Larry Summers is blacklisted from all his local farmers' market food stalls.

On November 20, I will be participating in Cellular Dance, a multimedia ballet by D. Ibbett. Come and watch the dancers do the #gastrulation, and more! Don't worry, I will not be dancing, but will give a mini-lecture on cellular movement. At the Museum of Science Boston. #DevBio #SciArt

Twenty years ago. THIS SHIT WAS 20 YEARS AGO. WHY WAS LARRY SUMMERS NOT CANCELLED WTF

Truly, the depths of righteous hatred of Larry Summers have only begun to be plumbed. 🤮

Today in F*CK Larry Summers news. I have hated this man for 20 years. Turns out I was not hating him enough.

🚨New paper! 🚨 @jasminealqassar.bsky.social led this work on the silk glands of the pantry moth. These two long tubes inside the caterpillar continuously make a ton of silk How does this special organ work? www.cell.com/iscience/ful... @cp-iscience.bsky.social 🧵THREAD🧵

5 headlines tonight on Charlotte Observer’s homepage: “Manolo's Bakery closes to protect customers” “Church members flee as federal agents arrive” “Super G executive describes agents dragging out teen employee” “Border Patrol questions people at Walmart” “Border Patrol sweep sparks fear”

I wanted to share probably the most important sermon I’ve given and it’s while I’m being arrested. It’s torture pure and simple what happens at #Broadview. I’m ok, though I was thrown to the ground and choked with my pectoral cross. A review of the video shows I was peaceful - did I deserve this?

I do not want to “Do my own research.” I want to pay trained accredited experts to do the research, trained accredited experts to report on findings, and trained accredited experts to make policy based on them. I am busy af with my own job, I don’t need to do eight zillion more.

reminder of cryptogyny, the hiding of women's contributions to science, technology, engineering, and medicine: "although three men received the Nobel Prize for penicillin, women participated significantly in the team effort that brought the drug to medical usefulness." www.jstor.org/stable/jj.55...

Lots of folks captioning aurora photos like "for a few minutes we didn't think about politics" guess I'm built different, every time I'm out trying to see night sky stuff I frequently think about how much light pollution is entirely preventable with just a tiny bit of regulation

This week's #FluorescenceFriday, we'll be treated with one of the classical models of #devbio, the neural crest cells. Here is a beautiful video of neural crest cells with GFP-tagged focal adhesion kinase (🔵) and LifeAct-RFP (🟣) migrating on a Fibronectin matrix. 📹: Adam Shellard

As a science educator, I should be teaching my students to approach the natural world and their fellow humans with kindness, compassion, curiosity, and humility.

Wonder if this is also happening to urban foxes? I'm not sure raccoons could even be cuter though, surely. Max cuteness exceeded?!

🚨 Our scientists have been at the forefront of #ProstateCancer screening and drug development for decades – leading innovative research and international clinical trials to give every man with prostate cancer the best chance of survival with a better quality of life. 🧵⬇️

Just 4 days until the start of I2K and its 33 totally free image analysis tutorials and events! Please share with your "home networks", especially early career researchers - the videos will be amazing and high-impact no matter how many people attend live, BUT (1/x)

This is some bullshit.

We are very happy to share our new PrePrint: Myosin VI orchestrates estrogen-driven gene expression in breast cancer cells. www.biorxiv.org/content/10.1... We characterise how Myosin VI is a key regulator of the Estrogen Receptor. Perturbation of Myosin VI impedes ER functionality.

What's not to love about an axolotl (Ambystoma mexicanum)? They've got feathery gills, tiny amphibian bodies & happy little faces 😀. But did you know they're masters of regeneration? Let's talk about why *being cute* and *growing back severed limbs* are, in fact, related.

Let's talk about the Burgess Shale, and the crazy animals it tells us about. It's a formation in Yoho Natl. Park (and others) in the Canadian Rockies near the town of Field, BC. It's made of mudstone (type of shale), deposited 508 MYA, in the middle Cambrian.

Another autoimmune charge against EBV! Get me a vaccine, stat.

they want to stamp out the entire profession of public health for a generation. same day they announce they’re closing the CDC museum

A bad thing is unfolding at NIH this week: It looks like the Trump administration is trying to replace key civil servant scientific leaders, the Institute Directors, with political hires. These directors control the NIH budget, tens of billions. A bit of a video explainer here: 1/ 🧪

And we knew this. This wasn't speculation. We studied it, we had the talking points. We trained volunteers to explain this to people. It's not a surprise. Rich people don't flee places with good quality of life when we increase the quality of life. They might try to cheat us, but they don't leave.

Defunding scientists for the nationality of who they co-author with or who they train. One of the most radical attack on freedom of speech in US history. A far right nationalist destruction of US science. Such a shameful time to be an American that this racist stupidity has become mainstream.

Love that dirty water

New preprint 🥳! We made photoclickable HaloTag ligands to precisely control protein labeling on living cells. With it, we can do some cool multicolor stuff. Huge congrats to Franzi and all co-authors! Check it out 👇 www.biorxiv.org/content/10.1...

I won't talk about NMeth @natmethods.nature.com forever (probably), but I do want to brag a bit about the November focus issue on cell segmentation and tracking, which is many ways is my last hurrah (and final editorial) for the journal. I am so proud of these papers!! www.nature.com/nmeth/volume...

Back on track: Funders hold all the cards. There's this flawed view that authors are consumers and journals are producers. Wrong. Funders and institutes are consumers. They contract authors to produce research, and they pay for journals to QC the work. Funders are the consumers. 8/n

3 years ago Elon enabled the funniest day in Twitter history.

A game changer in our hands... www.nature.com/articles/s41...

And if we think it’s bad now, imagine what it could look like, say, two months from a U.K. general election? Could imagine huge sums in US far right cash flooding in, much of what would only be declared after the election (our electoral rules really are a jape)

Love being reminded to do this every year. It's a win/win all round

The strides my GI colleagues at Johns Hopkins Kimmel Cancer Center are making in the fight against pancreatic cancer are amazing!

It’s officially potluck season withoffice parties galore. 🦃🥘 If, like me, you harbor an irrational fear of food poisoning, I’ve got you covered. Here’s your ID doctor–approved guide to surviving the season’s buffets w/out ending up in the ER. 🧤🍽️💀 open.substack.com/pub/bktitanj...

Ever wondered if analyzing your images by using intensity Z-projections impacts your data? Happy to announce my guest article in Microscopy & Analysis on that topic. It's a very short read but worth for everyone dealing with image analysis! buff.ly/KJ147tI #Microscopy #ZProjection #ImageAnalysis

Oh, I want to be a dolphin for a day!

Oh, I love this. A new species of sea anemone was discovered recently that parks itself on top of a hermit crab shell like a hat. It seems to feed partly off the crab's faeces, but it also excretes a hard shell that extends the crab's home. In return, it's carried around the seafloor like a king.

A wonderful collaboration between my lab and Andy Ellington and Edward Marcotte here at UT. We obtained lots of thermal stable plastic degrading enzymes from the deep sea (Guaymas Basin, Gulf of California)

Good interviews by my PhD supervisor, Don Ingber, and one of my rotation lab PIs and advisory committee members, Joan Brugge. Both epic scientists and good people. youtu.be/J1vXMTTxL1w?...

Before ACA, many Americans couldn’t afford insurance Alex Smith was a diabetic who got kicked off his Mom’s insurance at 26 He made 35k a year which was “too much” for Medicaid, but not nearly enough to cover insurance premiums He had to ration his insulin & died a month after losing insurance

Peiyao Fan, Yang Chen et al. @pku1898.bsky.social show that tubular ER extends into retraction fibers and #migrasomes through #microtubule-dependent ER extension and ER-plasma membrane contact sites in migrating cells. rupress.org/jcb/article/... #ER_literature #Migration #Organelles

😯

This is all so fuxked up. You shouldn't need an economics degree to access basic medical care. Or complex medical care! This is something every single person will need unless they die young, suddenly. Healthcare shpuld not be for profit. It's a fundamental service for a maintaining society.

ICYMI: New Online! Microtubules provide a mechanical link for YAP/TAZ signalling

I love to see the endoplasmic reticulum (ER, cyan) hitchhiking over microtubules (MTs, orange). Also the membrane dynamics are lovely. It's been a while, but here we are for a late #fluorescencefriday with some #microscopy #scicomm #scisky @cellcommlab.bsky.social focalplane.bsky.social 🧪🔬

A man rushed to the Broadview ICE facility searching for his wife. They followed every legal step, but ICE took her into another room and she vanished. He tracked her phone there when the signal died. Police told him to “look up her name online.” He sat in the parking lot, weeping, with no answers.

A critical role of FAK signaling in Rac1-driven melanoma cell resistance to MAPK pathway inhibition www.nature.com/articles/s41...

This is why I, as a clinician, strongly support a single-payer system. Think of it like the fire department. The modern fire department started as an insurance you could purchase; it ended as a public good, funded by all. Healthcare is no different.

Timeline cleanse!!!