Stiffness-induced impairment of GLUT4 trafficking in adult cardiomyocytes

Scientists harness the magic of CRISPR to map genetic drivers of basal-like breast cancer. This kind of breast cancer, which is usually triple negative, disproportionately affects younger women of color. 🧪 medicalxpress.com/news/2026-07...

People like Riley Gaines and Chris Rufo understand swaying public opinion leads to policy. Liberals for my money are too fucking earnest and are terrified of media manipulation. It’s a big reason we lose so much.

Plant actin networks are rapid mechano-adaptive scaffolds www.biorxiv.org/content/10.6...

This is how to speak to every single one of those sycophants.

Congrats we just made it impossible to come here for a PhD www.bostonglobe.com/2026/07/16/m...

I feel honored that my Perspective article with @mayorlab.bsky.social on collective cell migration has been featured in this special collection. Many thanks to the curators, @wumin-lab.bsky.social and Gabriele Stephan, as well as @jcb.org rupress.org/jcb/article/... #CellBio #CellMigration

The air quality in Michigan is the worst in the world right now. How did we get here?

Stopgap but will help save lungs corsirosenthalfoundation.org/instructions/

The Agency for Healthcare Research and Quality (AHRQ) has been gutted under this administration, and now its grantees are receiving termination letters en masse. Please help us report by submitting your grant and spreading the word! 🧪

What determines how epithelial cells divide when shape cues disappear? Our new work shows that division follows the axis of maximal stress anisotropy. This “principal-stress rule” links mechanics, proliferation, and homeostasis. Amazing work from @luanger.bsky.social. www.biorxiv.org/content/10.6...

Worth braving the hot marquee for the graduation prizes when ine of your supervisors wins two prizes. The kids are alright.

This 👆 They wrote out a "project 2025" type plan to gut the NIH and turn it into a haven for quacks and hobby science grifters. The cuts are bad, but stealing the brand and slapping it into pseudoscience is the real goal, and that'll have even deadlier long term consequences. End-of-science bad.

Please blow up the public comment (included below): BREAKING NEWS (7/15) — The administration wants to destroy Chaco Canyon without consulting Tribal Nations. It’s an irreplaceable historic & cultural site with 4,700 archeological sites that could be lost to the bulldozers of oil & gas development

So they get the islands back now, right?

Climate scholar: "Heat is a public health issue, an operational risk, a issue of national security, and a strain on financial resources. We need to discuss it in all these ways." ncnewsline.com/2026/07/15/w...

1. After pushing anti-trans laws to ‘protect women’s sports’, Project 2025’s Heritage Foundation now wants women’s sports gone to ‘assist fertility.’ Turns out it was about women’s sports all along—if getting rid of women's sports counts, that is.

The noises from all around make me think that something must justbhave happened in the football

Our preprint is now out in @natgenet.nature.com ! doi.org/10.1038/s415... We measured Sox2 promoter bursting dynamics with the SCR enhancer positioned at different distances within a genomic locus devoid of confounding effects in mESC: Main findings in the 🧵 below:

🧪 @aicjanelia.bsky.social and @scientistrachel.bsky.social have just published a new quantitative tool, OpticalFlow3D, for tracking amorphous motion in 3D. Try it out and let us know what you think! tinyurl.com/OpticalFlow3D

We can now steer blood vessels with dynamic forces and even re-direct vessels as they're growing! Great MIT News feature on our new paper in PNAS, outlining how a chance encounter with @ardemp.bskyverified.social helped us identify the role of PIEZO1 in this process: news.mit.edu/2026/mit-eng...

Curiously, UKRI initially uploaded a version of the strategy that said the QR funding formula would be reformed in 2027, but then said the correct date is 2030 Perhaps it would have been too controversial to shift the QR goalposts in the middle of a REF cycle? Full story:

The community can easily contribute, share, and improve the material. "Modular training resources for bioimage analysis" by Christian Tischer et al is free-to-view here > doi.org/10.1111/jmi....

Posted by @ipsumlorem.bsky.social on Facebook.

Wonshik Choi gave a talk last night at the biophotonics GRC that actually blew my mind. It covered the past ~10 years of work in his lab systematically trying to understand and correct for light scattering. I recommend reading his papers! This one is particularly strong imho doi.org/10.1038/s414...

This morning in Biddeford, Maine, a 26-year-old man said goodbye to his wife and daughter and left for work. Moments later he was dead, shot in the head by ICE agents, the second man ICE has killed in six days. ICE is killing our neighbors. ICE cannot be reformed. Abolish ICE.

University administration: "We need you to complete 26 hours of lab safety training 🧪 each year so that everyone is safe and responsible." Also university administration:

Happy #MicroscopyMonday! This movie shows the ZPA of a 🐭 limb bud. Cells expressing SHH are labeled 🌈. Notice the dynamic signaling protrusions extending from SHH-expressing ZPA cells - so cool! Membranes of cells not expressing SHH are 🔵 🧪 🔬 👩‍🔬 #DevBio #SciArt Credit: @christinaadaly.bsky.social

Posted mine. Random sampling of comments seems to be mainly opposed and the few in favor were identical copypasta.

Beyond proud to share our new paper, out in @natcomms.nature.com, where I'm co-last author 🎉 We mapped the transcription factors that control distinct EMT states in cancer and found some surprising new regulators along the way. 🧵 www.nature.com/articles/s41... (1/20)

Porcospini!

Every photo of Louis Pasteur looks like he's had enough of your bullshit, and I can't blame him.

You could get mad about dead senator discourse *or* you could enjoy this video of sea lions who have retaken an island with a decommissioned lighthouse off the coast of Oregon and now use the staircase as a giant slide.

These were suppose to be lessons not the play book

Restructuring research funding as a choice between discovery and application gets the economics wrong, the evidence wrong and the people wrong, argues Hiranya V. Peiris in a Comment article in Nature Reviews Physics. go.nature.com/4f28Cle ⚛️🧪

In www.biorxiv.org/content/10.6... Yean Ming Chew & I show that mutating the interPF interface in human MTs can allow them to assemble in GDP. We propose that tubulin molecules are captured indiscriminately at MT tips but then retained only if they can bind stably to a lateral nearest-neighbour.

Hello from Hyde Park

Thing that people were saying was going to happen for forty years happens roughly when they said it would happen; humanity shocked.

Conventional wisdom says rooftop solar meets **exisiting** electricity demand. What if rooftop solar actually **increases** electricity demand, improving living standards and driving economic growth? This is exactly what our new analysis of Pakistan's solar boom shows. Let's dig in.. 🧵

Perhaps the most prominent example is that the economics of cooling are transformed: - There's evidence solar and AC adoption have become co-determining purchases: households install panels partly to run ACs affordably.😎 - AC use on grid electricity prices would just be unaffordable for many.🤷‍♂️

Publsihed version www.frontiersin.org/journals/cel...

I’m constantly thinking this guy is a genius and then realising that all he is doing is identifying problems people care about and offering to do something about it. Is that really such a revolutionary idea? Yet it doesn’t seem to have ever occurred to the existing Democratic establishment

Gorgeous morning in #Bath

Unlike other organisms, Clytia medusae can repair damage so rapidly you can actually watch small wounds close within minutes. Larger wounds heal in less than an hour, a rate of recovery humans can only dream of. And no scar tissue is formed. 🔗 go.mbl.edu/jellyfish

Another #FluorescenceFriday. When the world is going crazy, I find some peace watching at these myeloid cells (🔴) going about their day. They exist in tissue surrounded by other cells (🔵), and you can see them popping up and down, going in and out of plane as they explore their surrounding.

An intrinsic cytoskeletal oscillator establishes neuronal polarity. Tien-chen Lin et al. Nature (2026). DOI: doi.org/10.1038/s415...

The new issue of#CYTOSKELETON is out! Check it out here: onlinelibrary.wiley.com/toc/19493592...