Michael Shribak (@shribak.bsky.social)

Super-resolution single-molecule fluorescence combined with quantitative phase contrast. This powerful combo enables ~0.05 nm optical path difference detection, < 20 nm resolution, and continuous live-cell imaging with digital staining doi.org/10.1101/2025... #Microscopy #CellBiology #OI-DIC #SMLM

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A correlative quantitative phase contrast and fluorescence super-resolution microscope for imaging molecules in their cellular context Fluorescence microscopy has been widely used to reveal the spatial distribution of specifically labeled molecules, but it is blind to cellular context. Quantitative phase contrast microscopy (QPC) pro... https://doi.org/10.1101/2025.10.13.682186