Not something you see in textbooks very often: tripolar mitosis.

An intracellular meteor shower. EB3 comets tracking growing microtubule plus-ends in a cultured cell.

Job alert! 📣 I’m looking for a research assistant to join my new team @idrm.ox.ac.uk Were using #zebrafish to understand gene-environment interactions that shape the heart 🫀generate natural diversity 🐸🐭 and contribute to congenital defects ❤️‍🩹 Full info below, and please share! 🫶🏻 bit.ly/467TO0M

Dynamic actin waves in a zebrafish embryo. Credit to @aaandmoore.bsky.social & Dvir Gur. #ZebrafishZunday 🧪

Adult zebrafish gill vasculature. Credit to @mathpreu.bsky.social. #ZebrafishZunday 🧪

Happy #FluorescenceFriday! I've shared this before but am reposting b/c I think the developing #lung is just so darn pretty! This is an E18.5 🐭 lung with 🟢 marking cells that express my favorite gene, Shh.🟣 marks cell membranes. 🔬 by @stjuderesearch.bsky.social postdoc👩‍🔬 @christinaadaly.bsky.social 🧪

This movie shows lysosomes (orange) and keratin (gray) in a cultured cell over 10 minutes.

I am proud to have contributed to this project during the first part of my postbaccalaureate fellowship, and excited to spend the rest of my time in this lab further investigating this structure.

We can now properly credit to @swinburnelab.bsky.social 🤩 Welcome to Bluesky! 🧪

Issue 22 is complete Explore our ToC: journals.biologists.com/jcs/issue/13... Our cover image shows Cyri-b-knockout cells with actin-driven lamellipodia in blue and microtubules in orange. See article by Whitelaw, et al. journals.biologists.com/jcs/article/...

Exciting new #Zebrafish research from the #WeinsteinLab, led by Jong Park! “Specialized gas-exchange endothelium of the zebrafish gill” — www.biorxiv.org/content/10.6... Amazing to see red blood cells moving through the gills! Don’t forget to check out the supplemental movies ;-)

Volumetric near-infrared light-sheet imaging of a calcium indicator (WHaloCaMP) in a zebrafish larval brain. Credit to @helenfarrants.bsky.social, William "Bill" Lemon, & Philipp Keller at @hhmijanelia.bsky.social. #ZebrafishZunday 🧪

Soliciting recommendations for 3D printers and lab supply blue prints. Please share and RT.

#KnowYourZDM: In 2019, a 10-year-old patient w/ a life-threatening lymphatic disorder was losing hope. Zebrafish to the rescue! Scientists created zebrafish with the same gene mutation and found a melanoma drug that fixed the fish. Then, doctors used the same drug on the patient to save his life! 🧪

Our work out in @devbiol.bsky.social, PDGFra is needed for 🧠 perivascular fibroblast development... ⬇️ perivascular fibroblast = ⬇️ perivascular macrophage...cross-talk? 👀 Led by Hannah Jones @hejcell.bsky.social w/ Kelsey Abrams, Sophia Kim, excited for more projects w/ @fantauzzolab.bsky.social!

Check out our recent preprint, "Live longitudinal imaging of meningeal cerebrovascular injury and its sequelae in adult zebrafish." lnkd.in/gN7z6th4

Live longitudinal imaging of meningeal cerebrovascular injury and its sequelae in adult zebrafish https://www.biorxiv.org/content/10.1101/2025.11.14.688311v1

“By performing longitudinal live imaging of intubated adult fish we observe vascular regrowth and immune responses to [meningeal cerebrovascular injuries] over time in the same animal with unprecedented resolution” New work from #WeinsteinLab at NIH

#ZebrafishFunFacts: Using the discarded slide film from his doctoral research, Professor and amateur artist Michael Barresi created a mosaic of an adult #zebrafish. Learn about his upcoming art installation on human embryos called 'Using Art to Demystify Science': www.smith.edu/news-events/... 🧪

Big congratulations to Hannah Somers, Digital Image Analyst at MDI Bio Lab, whose striking visualization of a zebrafish’s brain was named an Image of Distinction in the Nikon Small World competition — and featured by #NationalGeographic! #researchmatters #microscopymonday #lightsheet 🧪 🤝 🐟🎸 👩‍🔬

Slow-mo video of zebrafish mating. Credit to @zebrafish007.bsky.social. #ZebrafishZunday 🧪

Y’all saw it here on Bluesky FIRST. Trailer for #GarWeek 2025. JOIN US November 3-7!!!

#KnowYourZDM: Humans and #zebrafish carrying mutations in VEGFC or its receptor (FLT4) have defects in the formation of their lymphatic systems, which are important for draining lymph back into the circulation system.  As a result, these individuals display severe #lymphedema. 🧪

Endocardium, cells lining the heart chambers, in the beating heart of a two-day-old transgenic #zebrafish. Credit to @anjaliesch.bsky.social & Nikon Small World Competition. #ZebrafishZunday 🧪

We present multi-immersion Oblique Plane microscope (miOPM), a light-sheet platform that can be adapted to a wide range of applications, from sensitive live cell imaging to imaging organs and cleared tissues. www.biorxiv.org/content/10.1...

You’re not ready for gar slime:

@scadsai.bsky.social training coordinator @haesleinhuepf.bsky.social provided insights into his professional career in the podcast series “The Microscopists.” If you want to know why he'll never ask biologists for better images again, click here: 🍍 themicroscopists.bitesizebio.com/episodes/rob...

Wrong place, right time: Eda drives ectopic teeth formation in fish This Research Highlight showcases the work from Tyler Square and colleagues: journals.biologists.com/dev/article/...

Our latest preprint! Into morphogenesis, Yap, ECM, signaling, vertex models, feedbacks/robustness? There is something here for everyone. We discovered a positive feedback loop that extends inner ear canals, and a built-in mechanism that shuts it down when morphogenesis is done. tinyurl.com/464wsjhd

🚨🚨🚨 Please repost We are looking for postdocs to join our lab at NIH. Apply: www.nichd.nih.gov/research/atNICHD/Investigators/rocha/apply Learn more about training at NIH : www.training.nih.gov/research-tra...

Cancer cells are notoriously plastic, but what triggers the changes in cell state? In our new Nature (@nature.com)‬ paper, Miranda Hunter (@mrndhntr.bsky.social‬) found that mechanical pressure is a key to this switch. Check it out here: go.nature.com/47iwDm2

Happy to see our work, led by @ivanbassi.bsky.social, out today in @jem.org! #Zebrafish help us find new treatments for a #rare_disease affecting #lymphatic vessels! Congrats to all authors and thanks to #MDBRide4Rare, #ODC_UPenn, @erc.europa.eu for support @weizmanninstitute.bsky.social

Check this neuron infected with #SARSCoV2 being attacked by a microglia. Is this process beneficial or detrimental? Do we want therapies to inhibit microglia activation/neuroinflammation, but what if it means more neurons infecting other neurons? Neurovirology is fascinating! #FluorescenceFriday

💯

mRNA tech is some of the coolest, most powerful, most promising scifi shit humans are currently doing. They are being investigated to help with cancers, autoimmune diseases, M.S., stroke recovery, heart disease, diabetes, arthritis, and high cholesterol.

New short story from my postdoc in the Bassler lab is up on bioRxiv! Turns out our favorite quorum sensing responsive phage VP882 is a member of a larger family of phages that is distributed across multiple bacterial species and can eavesdrop on a universally conserved autoinducer. #PhageSky 🦠🧫

Hey friends - Daniocell is experiencing a temporary outage right now. The NICHD server it is hosted on got dropped from the NIH’s firewall list & so currently can’t be accessed outside the NIH. The relevant IT teams are working to resolve it. Sorry for any inconvenience. It’ll be back soon!!

I doubt that there is a single family in America that hasn’t benefitted directly from the NIH.

💥 Paper accepted (in principle) #cellfie 🤩 A long wait, a beautiful project, some amazing collaborations. Stay tuned for more ! ALT : how cells (and cell-like beads) are deformed in constraining vessels

Our latest issue is now live! On the cover is a species of Asian noodlefish characterized by their transparency due to the absence of red blood cells, slender bodies and scaleless skins, and a poorly ossified skeleton. www.cell.com/current-biol...

I might be a bit obsessed with blood vessels in the brain 🤓! Aren't they pretty? And check the red blood cells inside the small ones! Is it okay if I keep advertising our call for papers using more images of blood vessels in the brain? 😜🔬 #dementia #WomenInStem With @natureportfolio.nature.com

Galaxy of microtubules in the embryonic zebrafish eye. Credit to @zebrafish007.bsky.social. #ZebrafishZunday 🧪

The cell looks like Inkay Pokémon🔬 — yellow glowing arms, pink heart. Under attack by cyan bacteria🦠, but it’s just vibing on the glass, dancing🪩, unaware of the aftermath☠️. #FluorescenceFriday #Microscopy #CellBiology #mechanobiology @pasteuredu.bsky.social #hostpathogeninteraction @pasteur.fr

Development of a transgenic zebrafish embryo. Credit to Dr. Mario Mendieta-Serrano. #ZebrafishZunday 🧪

Why wait for #FluorescenceFriday if you can have a neat #zebrafish right now. (pic credit Amanda Garfield @cudevbio.bsky.social) #devbio

Alcian blue staining of cartilage in a two-headed zebrafish embryo. Credit to @jakeleyhr.bsky.social. #ZebrafishZunday 🧪

Check out the latest microscopy preprints including our recent favorite tool (LUCID) from #WeinsteinLab 🔥 🔗 to preprint: www.biorxiv.org/content/10.1...

High-resolution optical imaging of the meninges within the brain of an adult zebrafish. Credit to @zebrafish007.bsky.social & #WeinsteinLab. #ZebrafishZunday 🧪

Two great new #Zebrafish preprints from the #WeinsteinLab using a new transgenic that reports epigenetic silencing and activation! Great to study epigenetic changes in vertebrates, and we even did an ENU screen. Excellent work by @mmarvel.bsky.social et al. 🧪 www.biorxiv.org/content/10.1...

Have you noticed the rotating header images on our site? They're winners of a competition we ran in 2021. Thank you @gaparicio.bsky.social @rorylcooper.bsky.social @zebrafish007.bsky.social @ebardot.bsky.social & Markus Schliffka for the images! Give us a visit: thenode.biologists.com