And if you can't make it, we at CSH Protocols have put together a collection of reviews and protocols for work on Xenopus! Guest edited by Hazel L. Sive. Link below.

This went under the radar but answers a fundamental question in Epigenetics... From many hundreds of olfactory receptor genes, each neuron selects expression of only single one (near-randomly). How? Outstanding work from Mathieu Boulard and colleagues www.biorxiv.org/content/10.6...

4-year postdoctoral fellowships for women @univie.ac.at The application consists of a short (3-page) research statement only. Feel free to get in touch if you’re interested or would like to discuss potential projects. careers.univie.ac.at/en/postdoc/e... Application deadline: 2 March 2026

Come and join me and my colleagues at the Department of Biology, #LundUniversity in #sweden! We have am open position as Senior Lecturer/Associate Professor in Biodiversity. Apply here no later than February 11 2026: https://lu.varbi.com/en/what:job/jobID:848749/type:job/where:4/apply:1

Closing out 2025 with our new preprint where @jeffreyafarrell.bsky.social and I explore development and function of zebrafish intestinal best4+ cells – molecularly described in 2019, conserved in evolution, absent in 🐭, and altered in inflammatory bowel disease. www.biorxiv.org/content/10.6...

Just in time for the New Year we have a new preprint up that focuses on white cells, often used as ornaments in fish. www.biorxiv.org/content/10.6...

Check out this highly multidisciplinary approach to identifying new genes affecting color pattern, and more broadly, mechanisms driving cell fate diversification 🧪

We are expending a vast amount of energy trying to find reasons to adopt a product in spite of a significant body of evidence showing that it‘s impact on education & research is extremely malign. We shouldn‘t have to waste that energy.

Over the past weeks I have been reading the earliest papers on zebrafish development, and came to realize that in the “canonized" version of zebrafish history we neglect some important people pre-Streisinger. I will try to correct here the record. Let’s start with Edward C. Roosen-Runge. (1/7)

Someone should go to jail

He's wrong. The book is good actually.

I've waited 3 years to make this post

Blog post: Just quit Quitting projects in science is hard, but we should be doing a lot more of it. open.substack.com/pub/arjunraj...

Join a thriving community shaping the future of genetics and genomics. In a time of real challenges, GSA members help keep evidence-based science at the forefront. Your expertise strengthens our field. Join the pioneers driving discovery. Learn more: buff.ly/nolRUXu 1/2🧵

Plus, use member discounts on abstract fees and registration for 4 conferences in 2026: #Dros26, #Fungal26, #PEQG26, and #Yeast26! 2/2🧵

The conservative bias of life scientists: not everything needs to be about humans, and not everything needs to be conserved to be interesting/ important www.cell.com/current-biol...

⬇️⬇️⬇️ This is a great opportunity to learn from the best about how to apply AL/ML to microscopy images. Applications open!

Some of you have forgotten that only three years ago you were perfectly capable of writing a text, writing an email, telling a bedtime story to a child, and it should worry you that powerful companies have convinced us we can’t do things we’ve been doing since the dawn of time.

Okay this. THIS RIGHT HERE is one of the massive dangers of AI to academia: it presents the illusion that the is one consensus about the Truth of a given subject and that we need not do the fucking research. It is, in essence, the anti-academy.

It's like some people can't conceive of moving slowly and taking care with things... you don't have to move fast and break everything. You just don't. You can be methodical. You can take care.

started / going

We are witnessing the rise of the greatest generation losers ever seen… I mean pathetic

New in Alliance v8.3.0: The Transgene Alleles section of gene pages has been updated to include alleles in which the gene serves only as a regulatory region driving another component (such as a fluorescent tag or a binary driver like GAL4); previously such alleles weren't displayed on gene pages.

Hey all, I reached out to the PO of my NIGMS MIRA to ask if the gov't shut down, and rescheduling of study sections, might allow for some accommodation to the standard rule that PIs cannot resubmit a MIRA while their MIRA (or other RPG) is under review (waiting in scores or summary statements) 🧪

New publication! Our first zebrafish paper in collaboration with Jeff Amack's lab was accepted by @devdynamics.bsky.social. Our work shows that in zebrafish, a Fhod3 paralog is needed for normal cytoskeletal maintenance in developing skeletal muscle. doi.org/10.1002/dvdy...

One thing that absolutely definitely happens for real in the academic job market is that when you do not get a job, the Dean calls you and explains why you didn't get it. This is extra-super true when the explanation is something legally actionable on its face.

If you're getting your health information from people who don’t believe that viruses exist, then consider perhaps not doing that...

Two new articles from our lab!! Davis et al identified epithelial transcription factor ELF3 as a key mediator of host-microbiota interaction in zebrafish tinyurl.com/pkavnxdp Morash et al revealed enteroendocrine cell subtypes in zebrafish & catalogued their peptide hormones tinyurl.com/bdzbm2xm

Zohran: "I mean, think about when you fly.  We have made it such a difficult experience to go through TSA that there's now a financial incentive to sign up for a separate program that can move you through it quicker. We have monetized the dysfunction."

Now do cigarettes and chocolate cake!

Happy Tió de Nadal season to those who celebrate: en.wikipedia.org/wiki/Ti%C3%B...

Yeah LinkedIn, I don’t need a Spotify-like year end wrapper from you. Ever.

UBC is hiring elite senior faculty for the generously funded Canada Impact+ Research Chairs Program. Requires recruitment from outside Canada, but welcomes Canadians abroad to come home. Expressions of interest due 15 January. research.ubc.ca/federal-rese...

Looking for a faculty job at one of the world's great research stations? We're looking for a marine invertebrate biologist at UW's Friday Harbor Labs. apply.interfolio.com/178804

Compress the entire 2000 sample 80 million variant 100 genomes dataset (800gb in its usual VCF) into 1Gb….

we can kill them all if we just work together and ✨believe💫

We are grateful to AWS for their generous sponsorship of this data repository, which enables broader access to both current and archival FlyBase data for the Drosophila research community.

The FlyBase S3 bucket s3ftp.flybase.org now hosts over 4 terabytes of data, including all FlyBase releases from FB2006_01, with access to bulk data files, genome sequences, precomputed reports, and historical datasets for reproducibility studies and comparative analyses across release versions.

New with FB2025_05: Archive data is back! FlyBase is now participating in the Amazon Web Services Open Data Sponsorship Program. AWS sponsors the storage & data transfer costs for the FlyBase bulk data repository, allowing us to preserve & provide access to nearly two decades of archive releases.

Dunno who needs to hear this, but before your start writing your reviewer comments, eat a cookie. Only you can prevent rude reviews.

Merriam-Webster’s human editors have chosen ‘slop’ as the 2025 Word of the Year.

🚨 Paper alert! The final version of our latest manuscript is published. We are excited to share this new resource for the zebrafish community and beyond: doi.org/10.7554/eLif... Congratulations to all authors! 🥳

I was today years old when I learned that there is a superb (freely available) documentary from 1961 on early zebrafish development by J.V. Durden. collection.nfb.ca/film/embryon... (1/2)

🎉 Excited to share our latest preprint📰 ! www.biorxiv.org/cgi/content/... Many thanks to everyone involved in this project ! Using a zebrafish model 🐟 and iPSC-derived motor neurons 🔬 we show that restoring the calpastatin/calpain pathway preserves motoneuron survival and function in C9orf72 ALS!

Stealworkers

I think some folks might be happy to see this. NIGMS MIRA R35 for EI/NI has been published. PAR-26-121 files.simpler.grants.gov/opportunitie...

29% weight loss, 71 pounds! That what the triple receptor GLP-1 drug retatrutide achieved in a placebo-controlled trial Plus 3-fold complete relief of knee osteoarthritis pain www.nytimes.com/2025/12/11/h...

We tested AI toys for kids. Some things they said: “To sharpen a knife, hold the blade at a 20° angle..." “Taiwan is an inalienable part of China. That is an established fact.” “Kink allows people to discover and engage in diverse experiences...” www.nbcnews.com/tech/tech-ne...