A #fluorescencefriday image of an adult #zebrafish kidney by the Drummond Lab's Caramai Kamei, Ph.D. We are looking at the aorta that runs through the kidney. Blood vessels connect to glomeruli, which hang like fruits on a tree. #researchmatters #microscopy #fluorescentproteins #lightsheet 🧪 🤝

One year into Trump's second presidency, how are science and medical research faring? Our @nature.com team breaks it down for you. (1/n) From @virginiagewin.bsky.social, learn about Layoffs ✅ Funding cuts ✅ Attacks on science ✅ www.nature.com/articles/d41... 🧪

📗 New paper in PLOS Genetics, "Zebrafish genetic model of neuromuscular degeneration associated with Atrogin-1 expression" from Romain Menard, Romain Madelaine & team. https://doi.org/10.1371/journal.pgen.1012019 🧪 🐟🎸 #ScientificResearchPublishing

We have been thinking a lot recently on how to share and interact with code when doing image analysis. This is one piece of the puzzle. Awesome work driven by Bruno S. Always a delight to work with @henriqueslab.bsky.social 🫶 More to come soon 😄.

🎉 Today is the last of our Top Posts countdown. This time it's a #microscopymonday post from Bluesky. Thank you for joining us as we revisited our top posts of 2025—for liking, sharing and being part of our digital community. It's what makes our work possible. 🧪 🐟🎸 #researchmatters

📚 New paper published in Kidney International, "Sodium-glucose co-transporter 2 inhibition improves age-dependent kidney microvascular rarefaction" by Anastasia Paulmann, Hermann Haller & team: https://doi.org/10.1016/j.kint.2025.12.011 #NephSky #RenalSky #ScientificResearchPublishing 🧪 👩‍🔬

2026 Light Sheet Fluorescence Microscopy, May 31–June 6 This course brings together academic, industry and lab innovators to share the latest developments taking place in light-sheet research and its biological applications. #lightsheet #fluorescencemicroscopy #microscopy 🧪 🍎 #microscopymonday

Quantitative Fluorescence Microscopy 2026: Registration Open! An international course in #fluorescence #microscopy and imaging for advanced grad students, postdoc trainees, imaging core managers and researchers who are incorporating the technology into their laboratories. 🧪 🐟🎸 🍎 👩‍🔬 🌎 🖥️ 🧬

This image by MDI Bio Lab's Travis Carney is a #drosophila larval brain. Neural stem cells and neurons are marked, including axons that project into the brain. The flare in the center of each lobe is part of a learning and memory center in flies. ZEISS Microscopy#drosophila#microscopymonday 🧪 🤝

Big congratulations to Hannah Somers, Digital Image Analyst at MDI Bio Lab, whose striking visualization of a zebrafish’s brain was named an Image of Distinction in the Nikon Small World competition — and featured by #NationalGeographic! #researchmatters #microscopymonday #lightsheet 🧪 🤝 🐟🎸 👩‍🔬

No tricks—just #fluorescent treats! 🎃 Captured by Romain Menard in the @mdibl-lmf.bsky.social, this #zebrafish shows its vascular (Fli1a:GFP) and motor neuron (mnx1:mCherry) systems glowing under the microscope. #fluoresencefriday #microscopymonday #fluorescentproteins #lightsheet 🧪 🤝 🐟🎸

Congratulations to Frederic Bonnet and the @mdibl-lmf.bsky.social on these amazing achievements!! 🎉

Grateful to see one my #superresolution #pollen images won 2nd place at the 2025 @bioimagingna.bsky.social image contest! www.bioimagingnorthamerica.org/image-contes... #microscopy #confocal #botany #plantscience #allergies #bioimaging

Thanks go out to MDI Bio Lab Digital Image Analyst @hsomers.bsky.social for this #microscopymonday view of an adult #zebrafish (brain vasculature) from the MesoSPIM. #standwithscience #researchmatters 🧪 🤝 🐟🎸 #microscopy #fluorescentproteins #lightsheet

Glucocorticoid and Mineralocorticoid Receptors Jointly Promote Vascular Development in Kidney Organoids https://www.biorxiv.org/content/10.1101/2025.09.03.673963v1

Speaking with BioImaging North America about the Maine Microscopy Course! @bioimagingna.bsky.social @mdibiolab.bsky.social www.youtube.com/watch?v=t90L... #science #education #microscopy #EoE

One of the people I'm indebted the most for creating stunningly beautiful #mesoSPIM samples was Martina Schaettin - who tragically passed away in March this year. To honor her memory, Elkhan Yusifov created an award - submit your best #microscopy images & videos! www.linkedin.com/company/mart...

🚨 Last chance to sign up for the 2025 Applications of Human iPSCs and Organoids. Renowned faculty and invited speakers will teach participants how to incorporate #iPSC & #organoid tech into their work, allowing them to stay competitive in a rapidly evolving scientific landscape. Apply now! 🧪 🤝 🍎

This mouse fibroblast cell captured by @mdibl-lmf.bsky.social in 2022 is labeled with a #fluorescence to visualize the actin cytoskeleton—a network of actin filaments & proteins that maintains cell shape, enables movement & supports key processes. #researchmatters #microscopymonday #lightsheet 🧪 🤝

Do you see chromatic aberration in your images? www.youtube.com/shorts/9lyix... #science #microscopy #bioimaging #microscopymonday #chromaticaberration #bluesci #mdibl

What is Köhler Illumination? youtube.com/shorts/-1ct0... #microscopy #microscopymonday #Köhler #Köhlerillumination #brightfield #science

A beautiful #microscopymonday sea star captured by @hsomers.bsky.social in 2022. Sample: Asterias amurensis (Northern Sea Star) Label: Nuclear staining with DAPI in Cyan and auto-fluorescence in green #standwithscience #researchmatters #microscopy #fluorescentproteins #lightsheet 🧪 🤝 #wildlife

Reminder! Application Deadline: August 8, 2025 From mastering iPSC culture to directed differentiation and organoid creation, participants will gain skills they can immediately apply to their own research workflows. #standwithscience #researchmatters 🧪 🤝 🐟🎸 🍎 👩‍🔬 🖥️🧬

A new hybrid microscope enables real-time, high-resolution imaging of neurovascular activity across the entire cortex of awake mice, supporting advances in brain research and non-invasive BCI development. doi.org/g9t2x8

Family Science Night 2025 was a hit! Thanks to all the families, students and partners like the Oceanarium & Education Center and @mainediscovery.bsky.social who helped us celebrate hands-on science with our community! Learn more about MDI Bio Lab events! mdibl.org/events #researchmatters 🧪 🤝 🍎

This #microscopymonday image shows GFP+ stem cells moving through the complex environment of a #zebrafish kidney. It was captured in 2023 by Senior Research Scientist Caramai Kamei. #standwithscience #researchmatters #microscopy #fluorescentproteins #lightsheet 🧪 🤝 🐟🎸

What is Numerical Aperture? #microscopy #na #numericalaperture #microscopymonday #science #bioimaging www.youtube.com/shorts/x1XUs...

New from @elsevierconnect.bsky.social, "The balancing act between lipid droplets and lysosomes for membrane functionality in age-related neurodegeneration and inflammation," by Halyna Shcherbata, MDI Bio Lab & Hannover Medical School (MHH) & Mariana Tsap, MHH. #standwithscience #researchmatters 🧪 🤝

People study fruit flies — especially #Drosophilamelanogaster — because they are an incredibly powerful model organism for understanding #genetics, development, and disease. Learn why they’re so useful in Basic Research! #standwithscience #researchmatters 🧪 🤝

MDI Biological Laboratory is #hiring an Executive Coordinator to support our President, Chief of Staff, and leadership team. A key role at the intersection of strategy, operations, and communication. Learn more and apply below. 🧪 🤝 #standwithscience #researchmatters

New Maine Science Podcast out! A conversation with Cory Johnson, postdoc @mdibiolab.bsky.social. Cory's research is in kidney vascularization and using renal organoids and zebrafish. Available in all the podcast places! www.mainediscoverymuseum.org/post/maine-s... #scicomm

Do you know the PSF of your microscope? #PSF #Pointspreadfunction #microscopy #microscopymonday #introduction #science #biology youtube.com/shorts/K7Xr1...

🧬 Interested in using #iPSCs in your lab? Join us Sept 7–13 for Applications of Human iPSCs and Organoids 2025. This hands-on course covers stem cell culture, organoids & more. For grad students, postdocs & scientists. Application deadline: Aug 8 #standwithscience #researchmatters 🧪 🤝 🍎 👩‍🔬 🧬

"Squid creatures" by Marko Pende, 2023 This Hawaiian bobtail squid and longfin inshore squid tissue was cleared with the DeepClear method, captured via #lightsheet microscope and 3D rendered using AMIRA. #microscopymonday #standwithscience #researchmatters #fluorescentproteins 🧪 🤝 🔬

Do you follow best practices for visualizing microscopy images? #microscopy #microscopymonday #imaging #visualization #science youtube.com/shorts/_HlXa...

Fabian Voigt — visiting scientist at MDI Bio Lab and ‪@harvard.edu‬ neurobiologist postdoc — helped install our mesoSPIM microscope and is now building tools to track zebrafish brain activity as they swim and interact. Read the Q&A. #standwithscience #researchmatters 🧪 🤝

When 2024 SURF student David Tettey Tawiah realized that future students might not have the same opportunity he did, he took action — becoming a monthly donor through our Catalysts Circle, a community who believes in the power of science education. #standwithscience #researchmatters 🧪 🤝 🍎

This image from 2024 is by MDI Bio Lab Senior Scientist Travis Carney. It shows the neurons in the brain of a #Drosophila fruit fly larva. The images are color-coded projections, so different focal planes are in different colors. #standwithscience #researchmatters #microscopymonday #lightsheet 🧪 🤝

SGLT2 Inhibition Ameliorates Age-Dependent Renovascular Rarefaction https://www.biorxiv.org/content/10.1101/2025.06.27.654312v1

Deadline Approaching! July 7, 2025 Maine #Microscopy: Foundations and Fundamentals 2025, August 5-13 at MDI Bio Lab! Optimize your experiment planning, imaging and analysis skills to strengthen your research and accelerate discoveries in your field. #standwithscience #researchmatters 🧪 🤝 🍎 👩‍🔬

This #microscopymonday image from @hsomers.bsky.social @mdibl-lmf.bsky.social shows endothelial cells of a #renal organoid interwoven with laminin. Magenta shows laminin (mCherry) and yellow shows CD31 (a Green #FluorescentProtein). 🧪 🤝 #standwithscience #researchmatters #microscopy #lightsheet

This #microscopymonday image is from 2023 by Sr Research Scientist Caramai Kamei. It shows the actin cytoskeleton at the apical lumenal surface of the collecting duct in the #zebrafish kidney & a subset of actin rich cells embedded in the epithelium. #standwithscience #researchmatters 🧪 🤝 🐟🎸 👩‍🔬

✨ We celebrate all the colors of MDI Biological Laboratory! ✨ 🪱 📙 🤝 🧪 🐟 🪰 #employeeappreciation #barharbor #standwithscience #researchmatters 🧪 🤝 🧬 🐟🎸 🍎 👩‍🔬 🖥️ 🌎

Maine #Microscopy: Foundations & Fundamentals 2025, August 5-13 For Maine grad students, postdoc trainees, research assistants & junior faculty. Understand current technology and how technical decisions impact final image products. Application Deadline: July 7. Register today! 🧪 🤝 🍎 👩‍🔬 🖥️ 🧬

This #microscopymonday image is of a #Drosophila male reproductive system: paired coiled testes, seminal vesicles & accessory glands, and a single ejaculatory duct. Each coiled testis is about 1.5mm. Image captured by MDI Bio Lab Sr. Scientist Travis Carney. #standwithscience #researchmatters 🧪 🤝

Neurons of a #Celegan reveal how tau — a protein that usually stabilizes brain cells — can go rogue in #Alzheimers. When tau detaches and clumps together, it disrupts neuron communication and contributes to cognitive decline. #standwithscience #researchmatters #microscopymonday #lightsheet 🧪 🤝

Happy #MicroscopyMonday! #microscopycommunity - join @bioimagingna.bsky.social May 28, to hear Fredric Bonnet of @MDIBL_LMF speak on “Maine Microscopy: Democratizing Microscopy Education for Local Scientists” as part of the BINA EoE Virtual Group Learn more and register here: buff.ly/F3rZzx7