Quantitative Fluorescence Microscopy 2026: Registration Open! An international course in #fluorescence #microscopy and imaging for advanced grad students, postdoc trainees, imaging core managers and researchers who are incorporating the technology into their laboratories. 🧪 🐟🎸 🍎 👩‍🔬 🌎 🖥️ 🧬

This image by MDI Bio Lab's Travis Carney is a #drosophila larval brain. Neural stem cells and neurons are marked, including axons that project into the brain. The flare in the center of each lobe is part of a learning and memory center in flies. ZEISS Microscopy#drosophila#microscopymonday 🧪 🤝

Big congratulations to Hannah Somers, Digital Image Analyst at MDI Bio Lab, whose striking visualization of a zebrafish’s brain was named an Image of Distinction in the Nikon Small World competition — and featured by #NationalGeographic! #researchmatters #microscopymonday #lightsheet 🧪 🤝 🐟🎸 👩‍🔬

No tricks—just #fluorescent treats! 🎃 Captured by Romain Menard in the @mdibl-lmf.bsky.social, this #zebrafish shows its vascular (Fli1a:GFP) and motor neuron (mnx1:mCherry) systems glowing under the microscope. #fluoresencefriday #microscopymonday #fluorescentproteins #lightsheet 🧪 🤝 🐟🎸

Congratulations to Frederic Bonnet and the @mdibl-lmf.bsky.social on these amazing achievements!! 🎉

Grateful to see one my #superresolution #pollen images won 2nd place at the 2025 @bioimagingna.bsky.social image contest! www.bioimagingnorthamerica.org/image-contes... #microscopy #confocal #botany #plantscience #allergies #bioimaging

Thanks go out to MDI Bio Lab Digital Image Analyst @hsomers.bsky.social for this #microscopymonday view of an adult #zebrafish (brain vasculature) from the MesoSPIM. #standwithscience #researchmatters 🧪 🤝 🐟🎸 #microscopy #fluorescentproteins #lightsheet

Glucocorticoid and Mineralocorticoid Receptors Jointly Promote Vascular Development in Kidney Organoids https://www.biorxiv.org/content/10.1101/2025.09.03.673963v1

Speaking with BioImaging North America about the Maine Microscopy Course! @bioimagingna.bsky.social @mdibiolab.bsky.social www.youtube.com/watch?v=t90L... #science #education #microscopy #EoE

One of the people I'm indebted the most for creating stunningly beautiful #mesoSPIM samples was Martina Schaettin - who tragically passed away in March this year. To honor her memory, Elkhan Yusifov created an award - submit your best #microscopy images & videos! www.linkedin.com/company/mart...

🚨 Last chance to sign up for the 2025 Applications of Human iPSCs and Organoids. Renowned faculty and invited speakers will teach participants how to incorporate #iPSC & #organoid tech into their work, allowing them to stay competitive in a rapidly evolving scientific landscape. Apply now! 🧪 🤝 🍎

This mouse fibroblast cell captured by @mdibl-lmf.bsky.social in 2022 is labeled with a #fluorescence to visualize the actin cytoskeleton—a network of actin filaments & proteins that maintains cell shape, enables movement & supports key processes. #researchmatters #microscopymonday #lightsheet 🧪 🤝

Do you see chromatic aberration in your images? www.youtube.com/shorts/9lyix... #science #microscopy #bioimaging #microscopymonday #chromaticaberration #bluesci #mdibl

What is Köhler Illumination? youtube.com/shorts/-1ct0... #microscopy #microscopymonday #Köhler #Köhlerillumination #brightfield #science

A beautiful #microscopymonday sea star captured by @hsomers.bsky.social in 2022. Sample: Asterias amurensis (Northern Sea Star) Label: Nuclear staining with DAPI in Cyan and auto-fluorescence in green #standwithscience #researchmatters #microscopy #fluorescentproteins #lightsheet 🧪 🤝 #wildlife

Reminder! Application Deadline: August 8, 2025 From mastering iPSC culture to directed differentiation and organoid creation, participants will gain skills they can immediately apply to their own research workflows. #standwithscience #researchmatters 🧪 🤝 🐟🎸 🍎 👩‍🔬 🖥️🧬

A new hybrid microscope enables real-time, high-resolution imaging of neurovascular activity across the entire cortex of awake mice, supporting advances in brain research and non-invasive BCI development. doi.org/g9t2x8

Family Science Night 2025 was a hit! Thanks to all the families, students and partners like the Oceanarium & Education Center and @mainediscovery.bsky.social who helped us celebrate hands-on science with our community! Learn more about MDI Bio Lab events! mdibl.org/events #researchmatters 🧪 🤝 🍎

This #microscopymonday image shows GFP+ stem cells moving through the complex environment of a #zebrafish kidney. It was captured in 2023 by Senior Research Scientist Caramai Kamei. #standwithscience #researchmatters #microscopy #fluorescentproteins #lightsheet 🧪 🤝 🐟🎸

What is Numerical Aperture? #microscopy #na #numericalaperture #microscopymonday #science #bioimaging www.youtube.com/shorts/x1XUs...

New from @elsevierconnect.bsky.social, "The balancing act between lipid droplets and lysosomes for membrane functionality in age-related neurodegeneration and inflammation," by Halyna Shcherbata, MDI Bio Lab & Hannover Medical School (MHH) & Mariana Tsap, MHH. #standwithscience #researchmatters 🧪 🤝

People study fruit flies — especially #Drosophilamelanogaster — because they are an incredibly powerful model organism for understanding #genetics, development, and disease. Learn why they’re so useful in Basic Research! #standwithscience #researchmatters 🧪 🤝

MDI Biological Laboratory is #hiring an Executive Coordinator to support our President, Chief of Staff, and leadership team. A key role at the intersection of strategy, operations, and communication. Learn more and apply below. 🧪 🤝 #standwithscience #researchmatters

New Maine Science Podcast out! A conversation with Cory Johnson, postdoc @mdibiolab.bsky.social. Cory's research is in kidney vascularization and using renal organoids and zebrafish. Available in all the podcast places! www.mainediscoverymuseum.org/post/maine-s... #scicomm

Do you know the PSF of your microscope? #PSF #Pointspreadfunction #microscopy #microscopymonday #introduction #science #biology youtube.com/shorts/K7Xr1...

🧬 Interested in using #iPSCs in your lab? Join us Sept 7–13 for Applications of Human iPSCs and Organoids 2025. This hands-on course covers stem cell culture, organoids & more. For grad students, postdocs & scientists. Application deadline: Aug 8 #standwithscience #researchmatters 🧪 🤝 🍎 👩‍🔬 🧬

"Squid creatures" by Marko Pende, 2023 This Hawaiian bobtail squid and longfin inshore squid tissue was cleared with the DeepClear method, captured via #lightsheet microscope and 3D rendered using AMIRA. #microscopymonday #standwithscience #researchmatters #fluorescentproteins 🧪 🤝 🔬

Do you follow best practices for visualizing microscopy images? #microscopy #microscopymonday #imaging #visualization #science youtube.com/shorts/_HlXa...

Fabian Voigt — visiting scientist at MDI Bio Lab and ‪@harvard.edu‬ neurobiologist postdoc — helped install our mesoSPIM microscope and is now building tools to track zebrafish brain activity as they swim and interact. Read the Q&A. #standwithscience #researchmatters 🧪 🤝

When 2024 SURF student David Tettey Tawiah realized that future students might not have the same opportunity he did, he took action — becoming a monthly donor through our Catalysts Circle, a community who believes in the power of science education. #standwithscience #researchmatters 🧪 🤝 🍎

This image from 2024 is by MDI Bio Lab Senior Scientist Travis Carney. It shows the neurons in the brain of a #Drosophila fruit fly larva. The images are color-coded projections, so different focal planes are in different colors. #standwithscience #researchmatters #microscopymonday #lightsheet 🧪 🤝

SGLT2 Inhibition Ameliorates Age-Dependent Renovascular Rarefaction https://www.biorxiv.org/content/10.1101/2025.06.27.654312v1

Deadline Approaching! July 7, 2025 Maine #Microscopy: Foundations and Fundamentals 2025, August 5-13 at MDI Bio Lab! Optimize your experiment planning, imaging and analysis skills to strengthen your research and accelerate discoveries in your field. #standwithscience #researchmatters 🧪 🤝 🍎 👩‍🔬

This #microscopymonday image from @hsomers.bsky.social @mdibl-lmf.bsky.social shows endothelial cells of a #renal organoid interwoven with laminin. Magenta shows laminin (mCherry) and yellow shows CD31 (a Green #FluorescentProtein). 🧪 🤝 #standwithscience #researchmatters #microscopy #lightsheet

This #microscopymonday image is from 2023 by Sr Research Scientist Caramai Kamei. It shows the actin cytoskeleton at the apical lumenal surface of the collecting duct in the #zebrafish kidney & a subset of actin rich cells embedded in the epithelium. #standwithscience #researchmatters 🧪 🤝 🐟🎸 👩‍🔬

✨ We celebrate all the colors of MDI Biological Laboratory! ✨ 🪱 📙 🤝 🧪 🐟 🪰 #employeeappreciation #barharbor #standwithscience #researchmatters 🧪 🤝 🧬 🐟🎸 🍎 👩‍🔬 🖥️ 🌎

Maine #Microscopy: Foundations & Fundamentals 2025, August 5-13 For Maine grad students, postdoc trainees, research assistants & junior faculty. Understand current technology and how technical decisions impact final image products. Application Deadline: July 7. Register today! 🧪 🤝 🍎 👩‍🔬 🖥️ 🧬

This #microscopymonday image is of a #Drosophila male reproductive system: paired coiled testes, seminal vesicles & accessory glands, and a single ejaculatory duct. Each coiled testis is about 1.5mm. Image captured by MDI Bio Lab Sr. Scientist Travis Carney. #standwithscience #researchmatters 🧪 🤝

Neurons of a #Celegan reveal how tau — a protein that usually stabilizes brain cells — can go rogue in #Alzheimers. When tau detaches and clumps together, it disrupts neuron communication and contributes to cognitive decline. #standwithscience #researchmatters #microscopymonday #lightsheet 🧪 🤝

Happy #MicroscopyMonday! #microscopycommunity - join @bioimagingna.bsky.social May 28, to hear Fredric Bonnet of @MDIBL_LMF speak on “Maine Microscopy: Democratizing Microscopy Education for Local Scientists” as part of the BINA EoE Virtual Group Learn more and register here: buff.ly/F3rZzx7

This #microscopymonday video is of a #zebrafish embryo. It was imaged live, allowing researchers to investigate the impact of stress on #neutrophils (a type of white blood cells that play a crucial role in the body's #immunesystem) over time. #standwithscience 🧪 🤝 #fluorescentproteins #lightsheet

This #microscopymonday image depicts the blood vessels in a kidney organoid. At MDI Bio Lab, the Haller lab is studying kidney organoids to gain insight and potentially find mechanisms to stop the loss of blood vessels in the kidney. #standwithscience 🧪🤝

Looking forward to the @mesospim.bsky.social #lightsheet #Microscopy anniversary symposium in October with @preibischs.bsky.social @adamkglaser.bsky.social @christellelangevin.bsky.social & many more! And to the next mesoSPIM decade! 🔬 Thanks @nvladimus.bsky.social & Co for organizing it!

A leading Light Microscopy Facility in Maine, the goal of MDI Bio Lab's @mdibl-lmf.bsky.social is excellence in research support & training with a strong emphasis on #education. For instance, this #microscopymonday #zebrafish image is an example of a practice sample. #standwithscience 🧪 🤝 🐟🎸 🍎 👩‍🔬

"Beyond Resolution" captures the magic where art and science meet. After 18 months of collaboration with our scientists, MDI Bio Lab artist-in-residence Michael Takeo Magruder has transformed cutting-edge #microscopy into powerful visual art. 🧪 🤝

Caloric restriction is a well-established mechanism for improved protein recycling and increase longevity in #Celegans & other model organisms. This #microscopymonday image shows a C. elegan with marked germ granules. #standwithscience 🧪 🤝 #microscopy #fluorescentproteins #lightsheet

Happy #MicroscopyMonday! Nominate an academic @bioimagingna.bsky.social member for the 2025 Michael W. Davidson Memorial Award! 2025 submissions are now being accepted through May 23, 2025 & details are available here buff.ly/Bh9qo5r .

#HappyFluorescenceFriday! #microscopycommunity Join @bioimagingna.bsky.social celebrating World Microscopy Day on Sunday April 13th! Why did you become a microscopist? Try this fun frame (many thanks to @NhuTrieu.bsky.social for the design)