MDIBL Light Microscopy Facility
@mdibl-lmf.bsky.social
π€ 87
π₯ 138
π 7
Light Microscopy Facility
@mdibiolab.bsky.social
https://lmf.mdibl.org/
reposted by
MDIBL Light Microscopy Facility
Nikon Microscope Solutions
9 days ago
π π¬ Weβre thrilled to announce the winners of this yearβs
#NikonSmallWorld
in Motion video
#Microscopy
competition:
bit.ly/4mtjUk7
π₯ 1st place goes to Jay McClellan of Saranac, Michigan (USA) for his video capturing self-pollination in a thymeleaf speedwell flower.
#Microscope
#SciArt
#SciComm
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0
5
2
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
11 days ago
Thanks go out to MDI Bio Lab Digital Image Analyst
@hsomers.bsky.social
for this
#microscopymonday
view of an adult
#zebrafish
(brain vasculature) from the MesoSPIM.
#standwithscience
#researchmatters
π§ͺ π€ ππΈ
#microscopy
#fluorescentproteins
#lightsheet
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0
14
6
Speaking with BioImaging North America about the Maine Microscopy Course!
@bioimagingna.bsky.social
@mdibiolab.bsky.social
www.youtube.com/watch?v=t90L...
#science
#education
#microscopy
#EoE
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Exchange of Experience Virtual Group | May 28 2025 | Frederic Bonnet
YouTube video by BioImaging North America
https://www.youtube.com/watch?v=t90Ljk_sfGI
29 days ago
0
3
2
reposted by
MDIBL Light Microscopy Facility
about 1 month ago
One of the people I'm indebted the most for creating stunningly beautiful
#mesoSPIM
samples was Martina Schaettin - who tragically passed away in March this year. To honor her memory, Elkhan Yusifov created an award - submit your best
#microscopy
images & videos!
www.linkedin.com/company/mart...
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2
60
17
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
about 2 months ago
This mouse fibroblast cell captured by
@mdibl-lmf.bsky.social
in 2022 is labeled with a
#fluorescence
to visualize the actin cytoskeletonβa network of actin filaments & proteins that maintains cell shape, enables movement & supports key processes.
#researchmatters
#microscopymonday
#lightsheet
π§ͺ π€
0
5
2
Do you see chromatic aberration in your images?
www.youtube.com/shorts/9lyix...
#science
#microscopy
#bioimaging
#microscopymonday
#chromaticaberration
#bluesci
#mdibl
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What is optical aberration ?
YouTube video by LMF@MDIBL
https://www.youtube.com/shorts/9lyixIH23fM
2 months ago
0
3
1
What is KΓΆhler Illumination?
youtube.com/shorts/-1ct0...
#microscopy
#microscopymonday
#KΓΆhler
#KΓΆhlerillumination
#brightfield
#science
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What is KΓΆhler illumination ? #science #microscope #biology #optics
YouTube video by LMF@MDIBL
https://youtube.com/shorts/-1ct0wV6ZEI?si=2GrBidMAzbb-YZ9w
2 months ago
0
5
2
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
2 months ago
A beautiful
#microscopymonday
sea star captured by
@hsomers.bsky.social
in 2022. Sample: Asterias amurensis (Northern Sea Star) Label: Nuclear staining with DAPI in Cyan and auto-fluorescence in green
#standwithscience
#researchmatters
#microscopy
#fluorescentproteins
#lightsheet
π§ͺ π€
#wildlife
0
9
3
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
2 months ago
Reminder! Application Deadline: August 8, 2025 From mastering iPSC culture to directed differentiation and organoid creation, participants will gain skills they can immediately apply to their own research workflows.
#standwithscience
#researchmatters
π§ͺ π€ ππΈ π π©βπ¬ π₯οΈπ§¬
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Applications of Human iPSCs and Organoids 2025
https://mdibl.org/course/ipsc-organoid-2025/
1
5
2
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
2 months ago
This
#microscopymonday
image shows GFP+ stem cells moving through the complex environment of a
#zebrafish
kidney. It was captured in 2023 by Senior Research Scientist Caramai Kamei.
#standwithscience
#researchmatters
#microscopy
#fluorescentproteins
#lightsheet
π§ͺ π€ ππΈ
0
5
3
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
4 months ago
This
#microscopymonday
image is of a
#Drosophila
male reproductive system: paired coiled testes, seminal vesicles & accessory glands, and a single ejaculatory duct. Each coiled testis is about 1.5mm. Image captured by MDI Bio Lab Sr. Scientist Travis Carney.
#standwithscience
#researchmatters
π§ͺ π€
3
28
16
What is Numerical Aperture?
#microscopy
#na
#numericalaperture
#microscopymonday
#science
#bioimaging
www.youtube.com/shorts/x1XUs...
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What is Numerical Aperture (NA) ?
YouTube video by LMF@MDIBL
https://www.youtube.com/shorts/x1XUsTTt77Q
2 months ago
0
5
1
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
3 months ago
This image from 2024 is by MDI Bio Lab Senior Scientist Travis Carney. It shows the neurons in the brain of a
#Drosophila
fruit fly larva. The images are color-coded projections, so different focal planes are in different colors.
#standwithscience
#researchmatters
#microscopymonday
#lightsheet
π§ͺ π€
0
4
3
Do you know the PSF of your microscope?
#PSF
#Pointspreadfunction
#microscopy
#microscopymonday
#introduction
#science
#biology
youtube.com/shorts/K7Xr1...
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What is the Point Spread Function (PSF) of a microscope
YouTube video by LMF@MDIBL
https://youtube.com/shorts/K7Xr15jf-fY?si=PrZTmxg9tu4DNwom
3 months ago
0
1
1
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
3 months ago
This colorized
#microscopymonday
image from 2023 by Frederic Bonnet shows kidney cells of a pig: the nuclei in yellow, the cytoplasmic vesicle in green and the membrane in magenta.
#standwithscience
#researchmatters
@mdibl-lmf.bsky.social
#microscopy
#fluorescentproteins
#lightsheet
π§ͺ π€ ππΈ π π©βπ¬
0
3
1
Do you follow best practices for visualizing microscopy images?
#microscopy
#microscopymonday
#imaging
#visualization
#science
youtube.com/shorts/_HlXa...
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What are best practices for visualizing microscopy images ?
YouTube video by LMF@MDIBL
https://youtube.com/shorts/_HlXa3pURVQ?si=ZnWmnPgKoMVX7O1Q
3 months ago
0
8
3
reposted by
MDIBL Light Microscopy Facility
bioRxivpreprint
3 months ago
SGLT2 Inhibition Ameliorates Age-Dependent Renovascular Rarefaction
https://www.biorxiv.org/content/10.1101/2025.06.27.654312v1
0
3
2
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
3 months ago
Deadline Approaching! July 7, 2025 Maine
#Microscopy
: Foundations and Fundamentals 2025, August 5-13 at MDI Bio Lab! Optimize your experiment planning, imaging and analysis skills to strengthen your research and accelerate discoveries in your field.
#standwithscience
#researchmatters
π§ͺ π€ π π©βπ¬
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Maine Microscopy: Foundations and Fundamentals 2025
https://mdibl.org/course/me-micro-2025/
0
5
4
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
4 months ago
Maine
#Microscopy
: Foundations & Fundamentals 2025, August 5-13 For Maine grad students, postdoc trainees, research assistants & junior faculty. Understand current technology and how technical decisions impact final image products. Application Deadline: July 7. Register today! π§ͺ π€ π π©βπ¬ π₯οΈ π§¬
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Maine Microscopy: Foundations and Fundamentals 2025
https://mdibl.org/course/me-micro-2025/
0
3
2
reposted by
MDIBL Light Microscopy Facility
BioImaging North America
4 months ago
Happy
#MicroscopyMonday
!
#microscopycommunity
- join
@bioimagingna.bsky.social
May 28, to hear Fredric Bonnet of @MDIBL_LMF speak on βMaine Microscopy: Democratizing Microscopy Education for Local Scientistsβ as part of the BINA EoE Virtual Group Learn more and register here:
buff.ly/F3rZzx7
0
7
5
reposted by
MDIBL Light Microscopy Facility
5 months ago
Looking forward to the
@mesospim.bsky.social
#lightsheet
#Microscopy
anniversary symposium in October with
@preibischs.bsky.social
@adamkglaser.bsky.social
@christellelangevin.bsky.social
& many more! And to the next mesoSPIM decade! π¬ Thanks
@nvladimus.bsky.social
& Co for organizing it!
add a skeleton here at some point
0
19
11
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
5 months ago
A leading Light Microscopy Facility in Maine, the goal of MDI Bio Lab's
@mdibl-lmf.bsky.social
is excellence in research support & training with a strong emphasis on
#education
. For instance, this
#microscopymonday
#zebrafish
image is an example of a practice sample.
#standwithscience
π§ͺ π€ ππΈ π π©βπ¬
0
10
3
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
5 months ago
New chapter from Iain Drummond (MDI Bio Lab) and Heiko Schenk (Hannover Medical School) in Current Topics in Developmental Biology (
@elsevierconnect.bsky.social
): "Kidney development, injury and regenerationβZebrafish"
#standwithscience
π§ͺ π€ ππΈ
#SciencePublishing
doi.org/10.1016/bs.c...
0
2
1
reposted by
MDIBL Light Microscopy Facility
BioImaging North America
6 months ago
Happy
#MicroscopyMonday
! Nominate an academic
@bioimagingna.bsky.social
member for the 2025 Michael W. Davidson Memorial Award! 2025 submissions are now being accepted through May 23, 2025 & details are available here
buff.ly/Bh9qo5r
.
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Michael W. Davidson Memorial Award
The BioImaging North America (BINA) Michael W. Davidson Memorial Award is designed to support members who embody the mission and core values of BINA by demonstrating commitment, shared values and theβ¦
https://buff.ly/Bh9qo5r
0
9
4
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
6 months ago
Have you been thinking of enrolling the MDI Bio Lab's
#LightSheet
Fluorescence Microscopy course? Registration has been lowered to $1,000 β down from $3,500! This is a great opportunity for researchers/students to enhance their knowledge & skills in cutting-edge
#microscopy
techniques. π§ͺ π€ π π©βπ¬
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Light Sheet Fluorescence Microscopy 2025
https://mdibl.org/course/lsfm-2025/
0
11
7
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
6 months ago
A new publication is now out from
@commsbio.bsky.social
: "The small molecule ML233 is a direct inhibitor of tyrosinase function" by R.Menard, A.Baanannou, C.Halluin, D.Morse, S.Kuhn,
@jhgrabermdibl.bsky.social
, J.Strickland & R.Madelaine. π§ͺ π€ ππΈ π©βπ¬
#ScientificResearchPublishing
#ResearchPublishing
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The small molecule ML233 is a direct inhibitor of tyrosinase function - Communications Biology
In vivo, in vitro and in silico validation of the direct inhibition of Tyrosinase activity by the ML233 small molecule reveal a therapeutic candidate for skin disorders.
https://www.nature.com/articles/s42003-025-07973-5
0
6
3
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
6 months ago
Who knew something as simple as salt could look this mesmerizing up close? This stunning
#microscopy
image from
@mdibl-lmf.bsky.social
reveals the intricate beauty of salt crystals, captured using the Zeiss microscope (10x objective). π§ͺ π€
#microscopymonday
#fluorescentproteins
#lightsheet
0
3
2
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
7 months ago
MDI Bio Labβs Light
#Microscopy
Facility (LMF) went from unknown to Top 5 in the US, in just five years. In this article, LMF Director Frederic Bonnet discusses how if
#Maine
loses @microscopy_in_maine due to federal funding cuts, it loses a key hub for
#biomedical
research.
#standwithscience
π§ͺ π€ π¦
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A Powerful Light on Biology May Go Dark
https://mdibl.org/a-powerful-light-on-biology-may-go-dark/
0
3
3
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
7 months ago
For
@hsomers.bsky.social
, childhood days exploring Maineβs coast sparked a lifelong passion for
#marinebiology
. That curiosity led her to MDI Biological Laboratory, where scientists collaborate to push the boundaries of discovery. π§ͺ π€ π¦
#standwithscience
#standupforscience2025
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Science is the Lifeblood of Progress
https://mdibl.org/science-is-the-lifeblood-of-progress/
0
4
2
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
7 months ago
This is an image of a healthy mouse kidney, imaged on the MesoSPIM 4x objective.
#microscopymonday
#microscopy
#fluorescentproteins
#lightsheet
π§ͺ π€ π π©βπ¬
#NephSky
#RenalSky
Image courtesy of
@mdibl-lmf.bsky.social
0
10
3
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
7 months ago
"Take care of this place and protect the possibility for the continuation of our peaceful research." In 1945, this powerful message was found at the Univ of Tokyo Misaki Marine Bio Station in Japanβa reminder of why protecting scientific research matters:
ow.ly/xOKx50Vaaaq
#standwithscience
π§ͺ π€ π©βπ¬
0
2
4
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
7 months ago
A tardigrade for this week's
#microscopymonday
! (Zeiss LSM 980) 63x objective, image courtesy of
@mdibl-lmf.bsky.social
π§ͺ π€ π π¦ π§«
#microscope
#microscopy
#fluorescentproteins
#lightsheet
0
8
2
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
7 months ago
Indirect funding is essential for keeping the lights onβliterally! It covers vital costs like lab maintenance, utilities & admin support. Let's illustrate just how different research would look at MDI Bio Lab without it. π§ͺ π€ π©βπ¬
#standwithscience
#standupforscience2025
@standupforscience.bsky.social
0
10
4
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
7 months ago
Science research gave
@moonsledges.bsky.social
8 more years with her father after a Stage IV
#lungcancer
diagnosis. Now, science funding is at risk. We must protect researchβit isnβt just about discovery, itβs about life and hope. π§ͺ π€ 𧬠ππΈ π π©βπ¬
#standwithscience
@standupforscience.bsky.social
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The Power of Science, The Gift of Time
https://mdibl.org/the-power-of-science-the-gift-of-time/
0
26
10
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
7 months ago
Meet Dr. Anastasia Paulmann, a researcher in the Haller Lab working with a unique, short-lived fish to study how the
#vascular
system changes with age and test a new therapy to prevent those changes. π§ͺ π€ 𧬠ππΈ π π©βπ¬
#standwithscience
#standupforscience2025
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Dr. Anastasia Paulmann
YouTube video by MDI Biological Laboratory
https://youtu.be/iWo85RAH8dE?si=KJ1WriajkG6SrUtc
0
3
3
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
7 months ago
This image by Frederic Bonnet
@mdibl-lmf.bsky.social
shows pathways within renal
#glomeruli
(filtering units) from a mouse's kidney section. Blue delineates the delicate scaffolding of
#actinfilaments
, while orange reveals the
#glycoproteins
enmeshing the
#vasculature
. π§ͺ π€ π©βπ¬
#microscopymonday
0
8
2
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
8 months ago
Join us July 13-23 in Bar Harbor,
#Maine
, for our upcoming ReBilD program for emerging leaders in the field of regenerative biology & development! Don't miss this incredible opportunity for promising
#scientists
,
#graduatestudents
, and
#postdoctoral
researchers! π§ͺ π€ 𧬠ππΈ π π©βπ¬
#devbio
#AcademicSky
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ReBilD: Emerging Leaders in Regenerative Biology and Development 2025
https://mdibl.org/course/rebild-2025/
1
14
10
reposted by
MDIBL Light Microscopy Facility
Light-Sheet Fluorescence Microscopy (LSFM) course
8 months ago
Registration for LSFM at
@mdibl-lmf.bsky.social
6/1-6/7 is now open! This is an amazing academic environment, and is unique that all the major vendors will be there and students are ENCOURAGED to bring their own samples!
mdibl.org/course/lsfm-...
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Light Sheet Fluorescence Microscopy 2025
https://mdibl.org/course/lsfm-2025/
0
16
12
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
8 months ago
Join us at MDI Bio Lab (
@mdibl-lmf.bsky.social
) for an exciting 2025 lineup of
#microscopy
courses designed for researchers & professionals β May 16-23, June 1-7, and Aug 5-13!
#microscopymonday
#fluorescentproteins
#lightsheet
π§ͺ π€ 𧬠ππΈ π Learn more & enroll now!
mdibl.org/education/co...
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Courses
https://mdibl.org/education/courses/
0
6
5
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
10 months ago
"Leaf Walker" This beautiful
#tardigrade
crawling on a leaf was captured in the MDIBL
#LightMicroscopy
Facility in 2024 by Researcher Hannah Somers (lipid stain is shown in blue, DAPI staining is shown in yellow, autofluorescence is magenta). π§ͺπ€
#microscopymonday
#fluorescentproteins
#lightsheet
0
10
3
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
10 months ago
A kidney
#organoid
#nephron
, captured by Cory Johnson, via the MDIBL Light Microscopy Facility, is grown from human induced
#PluripotentStemCells
. Magenta marks epithelial cells that line the inner side of tubules in the nephron & cyan are nuclei of individual cells. π§ͺπ€
#microscopymonday
#lightsheet
0
6
1
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
10 months ago
Join us at MDI Bio Lab for an exciting 2025 lineup of
#microscopy
courses! π§ͺπ€ May 16-23: Quantitative
#FluorescenceMicroscopy
June 1-7:
#LightSheet
#Fluorescence
Microscopy August 5-13: Maine Microscopy: Foundations & Fundamentals Enroll now!
mdibl.org/education/co...
0
5
4
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
10 months ago
"Muscle Power" This image by Assistant Prof. Romain Madelaine & Research Assistant Caroline Halluin in 2021, depicts muscle tissue in
#zebrafish
; green slow fibers, magenta fast fibers & red mitochondria in skeletal muscle fibers are lit up using
#fluorescentprotein
technology. π§ͺπ€
#microscopymonday
0
6
2
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
9 months ago
This is a C. elegans embryo captured by
@dustinupdike.bsky.social
. The embryo is developing from a one-cell zygote to about a 50-cell embryo over the course of about three hours. The green germ granules partition to one cell lineage through these early stages of development.
#microscopymonday
π§ͺπ€
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2
15
3
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
10 months ago
In this
#microscopy
image, MDI Biological Laboratory's Bioimaging Data Scientist
@hsomers.bsky.social
used
#fluorescentproteins
to tag and detail a fish's blood vessels to create "2001, A Space Eyedyssey." π§ͺπ€
#fluorescencefriday
#fluorescentproteins
#lightsheet
0
11
2
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
9 months ago
π€ Did you know the Maine INBRE is a collaborative network comprised of 17 institutions, led by the MDI Biological Laboratory? Sponsored by the NIH's NIGMS, the
#MaineINBRE
strengthens Maineβs capacity to conduct competitive
#biomedicalresearch
. π§ͺπ€ππ₯οΈ π§¬ Learn more:
mdibl.org/research/res...
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IDeA Network of Biomedical Research Excellence
https://mdibl.org/research/research-programs/idea-network-of-biomedical-research-excellence/
0
4
2
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
9 months ago
π A new publication in Cells & Development from
@elsevierconnect.bsky.social
, "The evolutionary origin and mechanism of chordate tail regeneration. An ancient tale?" from
@murawalalab.bsky.social
:
doi.org/10.1016/j.cd...
π§ͺπ€
#ScientificResearchPublishing
#ResearchPublishing
#AcademicPublishing
0
2
3
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
9 months ago
#Zebrafish
can regenerate damaged tissues, including their eyes. The Madelaine lab is investigating the molecular mechanisms behind this remarkable ability, with a focus on vision restoration in conditions like
#maculardegeneration
and
#glaucoma
. ππΈπ§ͺπ€
#VisionScience
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Unlocking the Secrets of Vision Restoration
https://mdibl.org/unlocking-the-secrets-of-vision-restoration/
0
2
4
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
9 months ago
This 2020 image by
@hsomers.bsky.social
, was created using a Nikon spinning disk
#microscope
, and depicts the yellow muscles and purple ribosomes of the roundworm
#Celegans
. π§ͺπ€π§¬
#microscopy
#microscopymonday
#fluorescentproteins
#lightsheet
0
11
3
reposted by
MDIBL Light Microscopy Facility
MDI Biological Laboratory
9 months ago
ππ¬ An exciting new year of Courses & Conferences has kicked off at the MDI Biological Laboratory. Take a look at what's to come for our 2025 season! π§ͺ π€ 𧬠π
#AcademicSky
#SciEd
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2025 Is Packed with Campus Courses
https://mdibl.org/january-kicks-off-a-packed-year-for-campus-courses/
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