New 105 MP Sony IMX927 sensor (global shutter) capable of streaming data at 100 fps... 10.5 gigavoxels/sec. www.sony-semicon.com/en/products/...

Latest imaging data from our completely re-designed ExA-SPIM system. Expansion-assisted imaging (3X expansion, 0.3 NA) enables brain-wide imaging with high-contrast and <400 nm effective resolution.

First 3200 MP images from the LSST at the Vera C. Rubin Observatory! www.nature.com/articles/d41...

High-throughput line scanning confocal microscopy www.biorxiv.org/content/10.1...

We are excited to share our development of a new 10X lens with NA=0.50 over a 7.2 mm FOV and a 35 mm working distance (water), fully corrected from 400-850 nm. This lens will power our upcoming ExA-SPIM "2" and is available for dissemination - please get in touch if interested!

Looking forward to the @mesospim.bsky.social #lightsheet #Microscopy anniversary symposium in October with @preibischs.bsky.social @adamkglaser.bsky.social @christellelangevin.bsky.social & many more! And to the next mesoSPIM decade! 🔬 Thanks @nvladimus.bsky.social & Co for organizing it!

To look into: a Python alternative to ZEMAX... github.com/HarrisonKram...

New review out on imaging 3D cell cultures. Congratulations to Huai-Ching and @jonliu123 on leading this excellent new review! www.nature.com/articles/s41...

Curved light-sheet microscopy www.nature.com/articles/s41...

Thermal Lensing Effects in Light-Sheet Microscopy arxiv.org/abs/2504.02969

Sound-sheet microscopy - in this study, we introduce nonlinear sound-sheet microscopy (NSSM), a method to image targeted biological functions across cubic centimeters of opaque living tissue. www.science.org/doi/10.1126/...

New SPIM system underway!

Isotropic, aberration-corrected light sheet microscopy for rapid high-resolution imaging of cleared tissue www.biorxiv.org/content/10.1...

New 410 MP camera sensor coming in 2025 from Canon global.canon/en/news/2025...