Kidney injury and colocalization of complement C3, IgA, and IgG in glomerular immune-complex deposits of patients with #IgAnephropathy or #IgAvasculitis with nephritis. doi.org/10.1016/j.kint.2025.07.038 #MedSky #NephSky #OpenAcess #IgAN #glomerulardisease

Executive summary of the #KDIGO 2025 Clinical Practice Guideline for the Management of Immunoglobulin A Nephropathy ( #IgAN) and Immunoglobulin A Vasculitis ( #IgAV) doi.org/10.1016/j.kint.2025.04.003 #OpenAccess #MedSky #NephSky #glomerulardisease @imperialcollegeldn.bsky.social

Kidney ischemia and kidney dysfunction due to mass effect of a retroperitoneal tumor doi.org/10.1016/j.kint.2025.04.033 #NephSky #MedSky #acutekidneyinjury

The Single Cell Landscape of the Human Vein After Arteriovenous Fistula Creation and Implications for Maturation Failure doi.org/10.1016/j.kint.2025.08.024 #hemodialysis #geneexpression #inflammation #MedSky #NephSky

📣Apply to be Editor-in-Chief of Kidney International®.📣 🌍Lead the editorial vision of ISN’s flagship journal and help advance global kidney science. 📆Term: January 2027 to December 2031 ⏰ Application Deadline: November 3, 2025 ℹ️ lite.spr.ly/6002zr1g #MedSky #NephSky @theisn.org

Extrarenal “crescent” in multisystem granulomatosis with polyangiitis doi.org/10.1016/j.kint.2025.03.028 🔹Paravertebral masses in systemic vasculitides such as GPA are rare 🔹This pt had a rupture of the A. colica dextra leading to GI bleeding #MedSky #NephSky @i-med.ac.at @kronbichlerlab.bsky.social

A stronger type I interferon signature distinguishes ANCA-associated vasculitis phenotypes and predicts kidney prognosis doi.org/10.1016/j.kint.2025.07.034 #NephSky #MedSky #glomerulonephritis #ANCA @chuangers.bsky.social bsky.app/profile/chu-...

Causal assessment of #CKD-MBD biomarker alterations on #CKD progression through a g-formula analysis in the EQUAL Study doi.org/10.1016/j.kint.2025.07.032 #MedSky #NephSky #chronickidneydisease #dialysis @ki.se @amsterdamumc.bsky.social @unileiden.bsky.social

Jejunal compression in autosomal dominant polycystic kidney disease doi.org/10.1016/j.kint.2025.03.027 #MedSky #NephSky #ADPKD #kidneytransplantation #KTx @uclouvain.bsky.social #kidneydisease

A multinational qualitative study examined the perspectives and experiences of women with a kidney transplant on access to healthcare doi.org/10.1016/j.kint.2025.07.027 #MedSky #NephSky #kidneytransplantation #ckd #chronickidneydisease #WomensHealth

Commentary Intravenous immunoglobulin for chronic active antibody-mediated rejection: a signal of hope in an evolving field Böhmig G & Budde K doi.org/10.1016/j.kint.2025.05.034 Original article: doi.org/10.1016/j.kint.2025.04.023 #MedSky #NephSky #fibrosis #kidneyallograft

Commentary Distinguishing signal from noise: a new era of autoantibody testing in podocytopathies requires thoughtful approaches Ghasemi M and Weins A doi.org/10.1016/j.kint.2025.05.026 Original article: doi.org/10.1016/j.kint.2025.02.028 #MedSky #NephSky #FSGS #IgG #IgM #minimalchangedisease

An unexpected focus of infection after #kidneytransplantation doi.org/10.1016/j.kint.2025.04.006 🔍A vesicocutaneous fistula connected to an inactive bladder was identified as the infection focus in a KTx pt w/spina bifida 💡A multidisciplinary approach avoided cystectomy #OpenAccess #NephSky #MedSky

Protein UHRF1-mediated dual dysregulation of molecular chaperone GRP78 induces endoplasmic reticulum stress and aggravates #diabeticnephropathy doi.org/10.1016/j.kint.2025.07.023 #MedSky #NephSky #OpenAccess

Kidney-resident macrophages limit toxin-induced inflammation through their hallmark functions doi.org/10.1016/j.kint.2025.07.022 #NephSky #MedSky #AKI #acutekidneyinjury

Super-resolved optical imaging, reconstruction, and spatial analysis of whole mouse glomeruli via the Glomerulus Mapping and Analysis Pipeline doi.org/10.1016/j.kint.2025.07.024 #NephSky #MedSky #glomerulus @uwchemistry.bsky.social @uwcse.bsky.social @uwnephrology.bsky.social

Integrated spatial and functional metabolic profiling identified the thick ascending limb as a mitochondrial vulnerability hub in #acutekidneyinjury doi.org/10.1016/j.kint.2025.07.021 #OpenAccess #NephSky #MedSky #AKI @inserm.fr

Low prevalence of glomerulonephritis in transplanted kidneys from deceased donors with active #hepatitisCvirus infection doi.org/10.1016/j.kint.2025.07.026 #OpenAccess #KTx #kidneytransplantation #NephSky #MedSky

Angiopoietin-like 4 exacerbates renal tubular epithelial cell pyroptosis in acute kidney injury via integrin β5/FAK signaling pathway doi.org/10.1016/j.kint.2025.07.025 #AKI #MedSky #NephSky

Mini Review Patient preferences for #kidneyfailure treatments doi.org/10.1016/j.kint.2025.05.035 Aligning treatment decisions with patient preferences is central to person-centered care, but contemporary kidney care can fall short of this goal. @barnyhole.bsky.social #NephSky #MedSky #CKD

Integrated spatial and functional metabolic profiling identified the thick ascending limb as a mitochondrial vulnerability hub in acute kidney injury doi.org/10.1016/j.kint.2025.07.021 #OpenAccess #AKI #NephSky #MedSky

🌟🌟ICYMI🌟🌟 🔎Check out articles in the August KI doi.org/10.1016/j.kint.2025.05.014 🔹AI-selected features of tubulointerstitium prognosticate #kidney outcomes in #FSGS and MCD 🔹The children of mothers with #preeclampsia are at increased risk for #kidneydisease 🔹 𝘛𝘙𝘌𝘟1 gene variants associate with TMA

Cutaneous #histoplasmosis in a patient with a kidney transplant doi.org/10.1016/j.kint.2025.02.033 #NephSky #MedSky #kidneytransplantation #KINephrologyImage

Identifying multiple pleuroperitoneal communications by computed tomography #peritoneography doi.org/10.1016/j.kint.2025.03.024 CT peritoneography is a highly effective, noninvasive tool for detecting pleuroperitoneal communication, even in complex cases with multiple fistulas. #MedSky #NephSky

Is #preeclampsia ever “mild?” Lessons on long-term consequences for offspring from a Danish registry–based study Commentary by S Jesudason & G Piccoli doi.org/10.1016/j.kint.2025.05.011 Original article: doi.org/10.1016/j.kint.2025.04.017 #MedSky #NephSky #CKD #diabeticnephropathy #PedsNeph

Is the #Mayo prediction tool for #MGRS ready for prime time? Commentary by Jack Wetzels doi.org/10.1016/j.kint.2025.05.010 Original article: doi.org/10.1016/j.kint.2025.04.018 #MedSky #NephSky #kidneybiopsy #renalbiopsy #pathsky #CKD #chronickidneydisease #KICommentary

Nephrology Image “Strawberry milkshake” effluent in a patient undergoing peritoneal dialysis doi.org/10.1016/j.kint.2025.03.022 #NephSky #MedSky #dialysis #peritonealdialysis

#Renal Pathology Society/International #Kidney and Monoclonal Gammopathy Research Group consensus on pathologic definitions and terminology of monoclonal gammopathy–associated #kidneylesions doi.org/10.1016/j.kint.2025.04.007 #pathsky #nephsky #medsky #multiplemyeloma @renalpathsociety.bsky.social

Commentary The podocyte gets a pedicure: tiny nail clippers for podocyte foot processes L. Al-Rabadi and L. Beck doi.org/10.1016/j.kint.2025.05.009 Original article: doi.org/10.1016/j.kint.2025.04.010 #NephSky #MedSky #podocyte

Artificial intelligence and perspective for rare genetic kidney diseases Chen et al. doi.org/10.1016/j.kint.2025.03.033 #OpenAccess #KIMiniReview #artificialintelligence Find more articles in KI Kidney Genomic Medicine collection: www.kidney-international.org/content/kidn...

Preventing chronic kidney disease and maintaining kidney health: conclusions from a Kidney Disease: Improving Global Outcomes (#KDIGO) Controversies Conference doi.org/10.1016/j.kint.2025.04.005 #OpenAccess #NephSky #MedSky #ckd #chronickidneydisease #kidneydisease #kidneyhealth

#Zigakibart demonstrates clinical safety and efficacy in a Phase 1/2 trial of healthy volunteers and patients with IgA nephropathy doi.org/10.1016/j.kint.2025.05.006 #OpenAccess #NephSky #MedSky #IgAN #glomerulonephritis

🌟🌟ICYMI🌟🌟 🔎Check out articles in the July KI doi.org/10.1016/j.kint.2025.04.012 🔹 Benefits of #finerenone not affected by acute GFR changes 🔹 Autosomal dominant polycystic kidney disease in children 🔹 A natural product fights #tubulointerstitialfibrosis ⭐And More! #NephSky #MedSky #ADPKD #pedsneph

Postpartum counseling and interventions to reduce the risk of chronic kidney disease: back to the future doi.org/10.1016/j.kint.2025.03.031 #KIEditorial #NephSky #Medsky #preeclampsia #womenshealth #pregnancy #CKD #maternalhealth #hypertensivedisordersofpregnancy #chronickidneydisease

Metabolic disorder–associated kidney disease and diabetic kidney disease in developing countries doi.org/10.1016/j.kint.2025.03.034 #KIMiniReview #NephSky #MedSky #DKD #LMIC #diabetickidneydisease #MetabolicDisorder #kidneydisease #KidneyResearch

SEN, SLANH, and SEEDO consensus report on obesity-related kidney disease: proposal for a new classification doi.org/10.1016/j.kint.2025.06.013 #MedSky #NephSky #kidneydisease #obesity #meetingreport

Management recommendations for #kidneytransplantation in patients with plasma cell dyscrasia doi.org/10.1016/j.kint.2025.07.011 #NephSky #MedSky #kidneytransplant #multiplemyeloma #ALamyloidosis #monoclonalgammopathy #meetingreport

#KIControversies in Nephrology Fluid restriction in patients with AKI You can read the ✅Point ✅Counterpoint ✅Editor's summary in the July issue of KI doi.org/10.1016/j.ki... #MedSky #NephSky #acutekidneyinjury #aki

UBC9-associated SUMOylation contributes to β-catenin activation and kidney fibrosis doi.org/10.1016/j.kint.2025.07.005 #NephSky #MedSky #renalfibrosis #kidneyfibrosis

Q fever endocarditis and glomerulonephritis Q fever diagnosis is challenging: Only a minority of cases present with vegetation or positive blood cultures, making it hard to identify. doi.org/10.1016/j.kint.2024.12.023 #NephrologyImage #NephSky #MedSky #aki #acutekidneyinjury

Multi-omic factor analyses uncovered cross-compartment complexity of biological processes in kidney transplantation doi.org/10.1016/j.kint.2025.06.017 #NephSky #MedSky #transplantation #kidneybiopsy

ALECT2 amyloidosis in a patient with myeloma cast nephropathy Concomitant renal amyloidosis, typically AL, can be rarely seen in patients with myeloma cast nephropathy. doi.org/10.1016/j.kint.2024.12.024 #NephSky #MedSky #NephrologyImage #renalpath #kidneypath #kidneybiopsy #multiplemyeloma

To do or not to do—genetic testing for autosomal dominant polycystic kidney disease in children and adolescents doi.org/10.1016/j.kint.2025.05.001 Original article: doi.org/10.1016/j.kint.2025.02.026 #KICommentary #NephSky #MedSky #ADPKD

Iohexol clearance, but not estimated GFR, reveals a steeper GFR decline in patients with prediabetes doi.org/10.1016/j.kint.2025.06.019 #chronickidneydisease #ckd #prediabetes #glomerularfiltrationrate #gfr #iohexol

Phosphoenolpyruvate carboxykinase 1-mediated cataplerosis is required to maintain mitochondrial fitness and to avoid kidney disease progression doi.org/10.1016/j.kint.2025.06.018 #OpenAccess #KidneyDisease #MedSky #NephSky #aki #ckd

IgG4-related tubulointerstitial nephritis with negative contrast-enhanced computed tomography: diagnostic insights from 18F-fluorodeoxyglucose–positron emission tomography/computed tomography doi.org/10.1016/j.kint.2025.02.031 #KINephrologyImage #NephSky #MedSky #KidneyPath #RenalPath #kidneybiopsy

Humanizing flies with transgenic nephrin doi.org/10.1016/j.kint.2025.04.011 Original article: doi.org/10.1016/j.kint.2025.03.030 #KICommentary #NephSky #MedSky #nephroticsyndrome #genetickidneydisease

Indigenous spirituality and cultural knowledges provide strength and resilience to Aboriginal people with chronic kidney disease doi.org/10.1016/j.kint.2025.02.022 #chronickidneydisease #ckd

Integrating estimated glomerular filtration rate and kidney replacement therapy criteria within the definition of kidney failure doi.org/10.1016/j.kint.2025.06.015 #OpenAccess #NephSky #MedSky #chronickidneydisease #kidneyfailure

The randomized DIALIZE-Outcomes trial evaluated sodium zirconium cyclosilicate in hemodialysis doi.org/10.1016/j.kint.2025.06.016 #OpenAccess #MedSky #NephSky #cardiovasculardisease #CKD #chronickidneydisease #hemodialysis