1/ A well-prepared Jones methenamine silver stain can help localize immune deposits. By sharply defining the glomerular capillary basement membrane (GBM), the Jones stain confirms that the massive confluence of immune deposits is confined to the subendothelial region of the capillary wall.

In a 23yo M with proteinuria, hematuria and CKD, what is your diagnosis? #DiagnoseThis #nephsky #pathsky #renal #kidneypath

We have launched four neuropathology quizzes on our website! If you're interested in testing your neuropathology wisdom, head to our site. #neuropathology #neuromuscular #pathology #neuropath #neuronotes

1/ What is the best pathologic diagnosis? Clinical history in thread. #NeuroNotes #neuropath #pathology #neuromuscularpath

We're excited to share a new research publication from @aaronstorey.bsky.social, @glombandit.bsky.social, and Dr. Chris Larsen titled, "Proteomic Profiling of Complement Components in Glomerular Disease." Read here: https://pubmed.ncbi.nlm.nih.gov/41720186/ #ArkanaResearch #RenalPath #RenalResearch

Here is today’s #eyeSCANdy! Acellular scanning EM of a normal glomerular tuft showing the subpodcocytic capillary loop basement membranes following removal of the podocytes.  Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath

A sample from the pathology teaching slide set on Immunoglobulin and Complement-Mediated Glomerular Diseases with an MPGN Pattern of Injury, jointly prepared by Arkana Laboratories and @goKDIGO. http://KDIGO.org/guidelines/gd/ #KDIGO #pathology #renal #kidneypath

This is the biopsy from a 41yo Middle Eastern female who received a renal transplant a few years prior and presents with AKI. What is your diagnosis?  #DiagnoseThis #nephsky #pathsky #renal #kidneypath

We have officially launched four new neuropathology quizzes on our website! If you're interested in testing your neuropathology wisdom, head to our website to test your knowledge. #neuropathology #neuromuscular #pathology 

This 76-year-old male presented with complaints of muscle pain. Their past medical history is significant for Sjogren’s syndrome, fibromyalgia, peripheral neuropathy, hypertension and hyperlipidemia.

We asked Dr. Kowalewska about her path from med student to renal pathologist! Have you thought about exploring renal pathology? Check out our visitor program to begin exploring the world of renal! #path2path #roadtorenal #renalpathology #pathologist

We have officially launched four new neuropathology quizzes on our website! If you're interested in testing your neuropathology wisdom, head to our website to test your knowledge. #neuropathology #neuromuscular 

Here is today’s #eyeSCANdy! Acellular scanning EM of a normal glomerular tuft showing the subpodcocytic capillary loop basement membranes following removal of the podocytes.  Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath

A sample from the pathology teaching slide set on Immunoglobulin and Complement-mediated Glomerular Diseases with an MPGN Pattern of Injury, jointly prepared by Arkana Laboratories and @goKDIGO. http://KDIGO.org/guidelines/gd/ #KDIGO #pathology #renal #kidneypath

Meet Dr. K! We're so honored and excited to announce that Dr. Jolanta Kowalewska has joined Arkana's team of renal pathologists. Welcome to the team Dr. K! 👏🔬  #TeamArkana #renalpathologist #renalpathology

In a renal transplant recipient, what is your diagnosis? #DiagnoseThis #nephsky #pathsky #renal #kidneypath

Roughly 38% of all kidney discards can be attributed to “overcalling” or misinterpretation of kidney biopsy results. Stay tuned for more content about how to read and interpret donor biopsies. In the meantime, head to http://organdonationalliance.org to learn more about #NationalDonorDay. #ckd

Amyloid spicules, so-called "eyelashes", as they lay down perpendicularly along the glomerular basement membrane.  #UnderTheScope #renalpath #pathsky

Together, complications from diabetes and hypertension are responsible for 66-76% of all kidney failure cases in the States.  Tomorrow, February 14th, is National Donor Day—Head to http://organdonationalliance.org to learn more and get involved. #nationaldonorday #chronickidneydisease #ckd

What happens when oxalate nephropathy & renal embolic disease interact? How does this interaction impact kidney function? Find out the answer in our latest #Collidescope episode! #renalpath #kidneypath #pathsky #renalsky

Here is today’s #eyeSCANdy! Collecting duct showing ostia of an entering distal tubule.   Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath

Between 2021-2025, roughly 78% of all kidney transplants in the United States were deceased donor transplants.  February 14th is National Donor Day—Head to http://organdonationalliance.org to learn more and get involved. #nationaldonorday #chronickidneydisease #ckd

In this week's #Collidescope case, Dr. Charles investigates a case of oxalate nephropathy & renal embolic disease. Watch the episode to learn more about how these two diseases interact and affect kidney function.  #renalpath #kidneypath #pathsky #renalsky

Over a half a million people with kidney disease in the United States are on chronic dialysis due to the lack of an available donor kidney.  February 14th is National Donor Day—Head to organdonationalliance.org to learn more and get involved. #nationaldonorday #chronickidneydisease #ckd

What happens when oxalate nephropathy & renal embolic disease interact? How does this interaction impact kidney function? Find out the answer in our latest #Collidescope episode! #renalpath #kidneypath #pathsky #renalsky

A sample from the pathology teaching slide set on Immunoglobulin- and Complement-mediated Glomerular Diseases with an MPGN Pattern of Injury, jointly prepared by Arkana Laboratories and @goKDIGO. http://KDIGO.org/guidelines/gd/ #KDIGO #pathology #renal #kidneypath

Dr. Charles is back with another #Collidescope case! Learn about how oxalate & renal embolic disease interact and affect kidney function! #renalpath #kidneypath #pathsky #renalsky

The differential diagnosis for interstitial hemorrhage includes hemorrhagic necrosis in the setting of renal artery thrombosis, infection (e.g. herpes simplex virus, adenovirus, hantavirus, Rickettsia),...(1/2) #TeachingPoints #kidneypath #renal #pathology

In a patient with AKI and hematuria, what is your diagnosis? #DiagnoseThis #nephsky #pathsky #renal #kidneypath

(1/2) A case of florid ALECT2 type amyloidosis. This is a Hispanic patient who had not seen a physician in several years. Leukocyte chemotactic factor 2 type amyloidosis (ALECT2) is a form of amyloid of unknown etiology.  #renal #pathtwitter #kidneypath #underthescope

A sample from the pathology teaching slide set on Anti-glomerular Basement Membrane (Anti-GBM) Antibody Glomerulonephritis, jointly prepared by Arkana Laboratories and @goKDIGO. http://KDIGO.org/guidelines/gd/ #KDIGO #pathology #renal #kidneypath

(1/3) Chronic active T cell-mediated rejection (TCMR) was included in the 2017 Banff classification system for the evaluation of kidney allografts (see reference).  #TeachingPoints #kidneypath #renal #pathology

Here is today’s #eyeSCANdy! Corrugated lumen of a renal artery following removal of endothelial cells.  Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath

In a patient with subnephrotic proteinuria, negative immunofluorescence, and segmental foot process effacement, what is your diagnosis? #DiagnoseThis #nephsky #pathsky #renal #kidneypath

(1/3) A case of active lupus nephritis in a limited sample. Only renal medulla was present for IF. Two glomeruli total were present for LM and paraffin IF was performed, which demonstrated near "full house" staining. #GlomGoals #biopsyadequacy #pathtwitter #renaltwitter

A sample from the pathology teaching slide set on Lupus Nephritis, jointly prepared by Arkana Laboratories and @goKDIGO. http://KDIGO.org/guidelines/gd/ #KDIGO #pathology #renal #kidneypath

Here is today’s #eyeSCANdy! Acellular scanning EM showing discrete GBM perforations from a patient with focal necrotizing and crescentic glomerulonephritis.  Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath

Collapsing glomerular lesions are aptly named, given the prominent “collapse” of glomerular tuft capillary loops. There is also hyperplasia and hypertrophy of overlying epithelial cells, and protein resorption droplets may be abundant (see arrow). #TeachingPoints #kidneypath #renal #pathology

In a patient with RPGN and this morphological finding on biopsy, what is the most likely diagnosis? #DiagnoseThis #nephsky #pathsky #renal #kidneypath

(1/2) A case of lambda light chain cast nephropathy in a limited sample. The entire biopsy consisted of renal medulla. #GlomGoals #biopsyadequacy #renaltwitter #pathtwitter

We're excited to share that Dr. Jamie Singh and Dr. Shree Sharma will each be giving a lecture at the National Kidney Foundation Spring Clinical Meeting in May. They will be teaching at the pre-conference session on May 6, so please make sure you register! https://www.kidney.org/spring-clinical

A sample from the pathology teaching slide set on Anti-glomerular Basement Membrane (Anti-GBM) Antibody Glomerulonephritis, jointly prepared by Arkana Laboratories and @goKDIGO. http://KDIGO.org/guidelines/gd/ #KDIGO #pathology #renal #kidneypath

We're thrilled to celebrate Dr. Tiff Caza, who has officially surpassed 100 publications! 🥳 This incredible achievement reflects Dr. Caza's commitment to excellence and her outstanding impact in renal pathology and patient care. Congratulations, @glombandit.bsky.social ! #renalpathology #pathology

(1/2) This 76 y/o male presented with complaints of muscle pain. Their past medical history is significant for Sjogren’s syndrome, fibromyalgia, peripheral neuropathy, hypertension and hyperlipidemia. Laboratory studies showed normal CPK and elevated CRP. #neuropathology #neuromuscular #pathsky

Here is today’s #eyeSCANdy! Acellular scanning EM showing a glomerulus with fibrocellular crescent (right). Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath

Prominent interstitial eosinophils (see arrow) are most often associated with allergic-type acute interstitial nephritis (AIN).  #TeachingPoints #kidneypath #renal #pathology

This is the albumin immunofluorescence stain form a biopsy from a patient with recent COVID pneumonia and nephrotic syndrome. What is your diagnosis? #DiagnoseThis #nephsky #pathsky #renal #kidneypath

(1/2) A case of IgA nephropathy but in a limited sample. Cortex was present for immunofluorescence microscopy so, a diagnosis could be made.  #renalpathology #renalsky #GlomGoals #biopsyadequacy

Here is today’s #eyeSCANdy! Acellular scanning EM showing a glomerulus with fibrocellular crescent (top). Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath

A sample from the pathology teaching slide set on Lupus Nephritis, jointly prepared by Arkana Laboratories and @goKDIGO. http://KDIGO.org/guidelines/gd/ #KDIGO #pathology #renal #kidneypath