How do you know if a microscopy experiment can actually resolve a biological structure? Introducing VLab4Mic, a platform that predicts structural resolvability before you go to the microscope Led by Damián Martinez and Bruno Saraiva at @henriqueslab.bsky.social www.biorxiv.org/content/10.6...

How does an orbiting spherical tissue suddenly break symmetry and sprout invasive strands? We can predict this behavior from the initial morphology! Hi, I’m @jiwon-kim.bsky.social from @ianywonglab.bsky.social.

Our thread is now up at @epimechfc.bsky.social 💗 Take a look if you are interested in how a living tissue knows how to sculpt itself!

How do epithelial cells integrate mechanical and biochemical signals to control their behavior? I am @ronjahoutekamer.bsky.social, and in this thread, I’ll show you how force transduction connects to biochemical signaling, and how it activates ERK by inducing biochemical ligand shedding.

Make your own PDMS+micromirror device for single-objective light-sheet SMLM: www.biorxiv.org/content/10.6...

It's funky axons time 🔬 🧪

say hello to Laurent! just started his PhD, and new on bluesky. cloning-wizzard and optogenetics-guru, using microscopy to link signaling & mechanics

📣 Submission deadline extended for special issue "Taking the Stage: The Future of Microscopy"! The Journal of Microscopy has launched an open call for papers for an exciting new special issue which will feature submissions by Early Career Researchers. Deadline extended: 30 April 2026

🚨📰Now online in its full form www.nature.com/articles/s41...

Hi all fans of #smart #microscopy, we from @zeiss-microscopy.bsky.social have just published a new application note: "Study Mitotic Progression with Guided Acquisition – Rare Event Detection" go2.zeiss.com/ODk2LVhNUy03... For more details: forum.image.sc/t/applicatio...

Recording of talk for the french bioimaging network RTmfm. My PhD work in @olivierpertz.bsky.social lab (closed-loop optogenetics, microfabrication, image analysis w/ Convpaint). On smart microscopes: the issue of interoperability and some preliminary results on LLM control :) youtu.be/Gvaw2kWsVIk

Such an intriguing concept for the future of smart microscopy, especially appreciate how the paper builds on the foundations of knowledge creation, rather than arguing from a technolocial perspective first!

🔬 In this new open access paper, the authors introduce a theoretical framework that reconceptualises smart microscopy as a partner in scientific investigation. Central to their framework is the concept of the ‘epistemic–empirical divide’ in cellular investigation, ...

Open Blink: Low-cost TIRF microscopy for super-resolutionimaging via μManager https://www.biorxiv.org/content/10.64898/2026.03.10.710894v1

Excited to see direct streaming of @openmicroscopy.org @zarr.dev datasets in #syGlass! Exploring huge images without upfront download is just what we’ve been working toward with cloud-optimized formats. Great to have tools connecting the ecosystem of imaging repositories, now including VR 🙌

Check out and give feedback on the latest pre-release 0.7.0rc0! You can install with `pip install "napari[all]>=0.7.0rc0"` or via the bundled app. 😁 🥳 The release notes, with highlights, include so many great new features and changes: napari.org/dev/release/...

Tiny, transparent, and now charted! Our brain atlas of adult Danionella cerebrum includes >200 annotated regions, 29 whole-brain in situs, and male/female reference volumes – openly available, versioned and extendable. Work by @nkadobyansky.bsky.social and team. www.biorxiv.org/content/10.6...

Calling for protocols on The Basics: get a protocol recorded and peer reviewed, and help a colleague learn the tips and tricks by *seeing how it's done* You don't need to include new results and it does not have to be your original protocol. Just cite well and share the know-how 💕🔥 Get in touch!

napari needs your help! Has napari helped you make cool and groundbreaking discoveries? We'd love to highlight that in our docs. Please tell us about it! You can fill in this survey: napari.typeform.com/to/vTCKeTKv and/or, as ever, drop by our chat room or meetings: napari.org/dev/community/ 🙏

Live in 1h! www.youtube.com/live/infTDml...

🚨Preprint! Happy to share the research from my PhD “Genome delivery of a contractile tailed phage and its superinfection exclusion mechanism”. We use cryoEM to study the genome ejection of the phage T4, revealing how the tape measure protein regulates the process. www.biorxiv.org/content/10.6...

Leclech, C., Cardillo, G., Roellinger, B., Zhang, X., Frederick, J., Mamchaoui, K., Coirault, C., & Barakat, A. I. (2025). Micro-Scale Topography Triggers Dynamic 3D Nuclear Deformations. Advanced science, 12(11), e2410052. #EpithelialMechanics doi.org/10.1002/advs...

Looking for a PhD position at the intersection of AI, imaging, and gene therapy? Apply for this position in my lab: tinyurl.com/2a2v6tvx Part of sfb1690.uni-goettingen.de to study hearing, vision, and more. Plus, you can create pretty pictures as the one below :).

Very happy that MuViT, our (CVPR 2026!) work on learning across spatial scales in microscopy w transformers, is out! Check Martin's thread for a nice walkthrough :) Big thanks to my advisors @maweigert.bsky.social @gioelelamanno.bsky.social! 🖥️: github.com/weigertlab/muvit 📜: arxiv.org/abs/2602.24222

Excited to share our new paper (CVPR 2026 🚀): "MuViT: Multi-Resolution Vision Transformers for Learning Across Scales in Microscopy" which enables local predictions to use global context. Great work led by @albertdm.bsky.social & another fun collab w @gioelelamanno.bsky.social! @scadsai.bsky.social

Go Lucien!! Love to see it

PAPER OUT ✨ How can we make smart microscopy more interoperable? What are the technical and cultural challenges? 30+ people from academia and industry propose a roadmap: doi.org/10.1515/mim-... Also a review of applications and repo of implementations. Join the discussion! smartmicroscopy.github.io

Our article on how to use micropatterned presynapses-on-glass is out in its final form in the latest issue of the Journal of Neuroscience @sfnjournals.bsky.social: www.jneurosci.org/content/46/8... The cover went to the special section on social neuroscience, so here's our #notthecover attempt

Get in touch if you want to be paid to work with us this summer. We are particularly interested in hearing from scientists who are interested in software development!

Rewrote my Python bioformats wrapper (from aicsimageio/bioio) as a standalone package: - fully bootstrapped Java setup (just pip install) - lazy, repeatably-indexable Array object - fully spec-compliant OME-Zarr group obj. - xarray/dask exports github.com/imaging-form... v0.0.rc1 on PyPI

🎥 Don't miss this recording of the #VirtualPub with @lhinderling.bsky.social PertzLab on Smart Microscopy workflows - for automation of optogenetic targeting & beyond. Great talk 👏 🔽 youtu.be/YpGmMzrFJ80

Apply to join us this July for a crash course on Python & bioimage analysis tailored specifically for beginners! Applications due May 18th 🔬💻 #BoBiAC2026 bobiac.github.io

And save >80% on the cost by pooling 6 or more plasmids into a single sample using our free SAVEMONEY algorithm! elifesciences.org/articles/88794 colab.research.google.com/github/Masaa...

Vorholt Lab re-created endosymbiosis in the lab: injected bacteria into a fungus and evolved a heritable partnership. Evolution, fast-forwarded. doi.org/10.1038/s415...

I'll never get tired of lazily browsing elastix-coregistered #WSI data in @napari.org using the upcoming @openmicroscopy.org ome-zarr @zarr.dev format version that allows to specify and read transformations directly from the image data itself. Data source: rodare.hzdr.de/record/3131

Enhance your timeline on #InternationalDayOfWomenAndGirlsInScience by following our two(!) Starter Packs of outstanding Group Leaders and Senior Scientists from the #zebrafish community! 🐟 🧪 #WomenInScience Volume 1: go.bsky.app/4BegEjv #WomenInScience Volume 2: go.bsky.app/VoebYrt

Hello epithelial mechanics fans!! I’m Juanma @juanmagararc.bsky.social 👋 I work on cell mechanics (see celldynamicslab.com) and use Flipper-TR FLIM to probe membrane biophysics in cells. Join me on this tour about Flipper: what it measures, strengths, advice, cool case studies, and cute drawings!

I witnessed the Flipper-TR development from day 1. I remember how I told myself "it can't work" when I first saw the concept. Until it actually worked beautifully! It took a decade, but now Flipper-TR is a widely used tool and an inspiring tale. Congrats to the many who contributed to this journey!🧪

1/ 🚀🧪🤖 Big update for #Omega — the LLM-powered autonomous agent for bioimage analysis in @napari.org ! Custom LLM endpoints, layer actions, plugin extensibility, agentic widget maker, modernized UI, & 30+ fixes. Here's what's new in version *2026.2.8.2*:

Busy #cellfie 🧪

Electrifying story from @ritamateus.bsky.social lab. @mpi-cbg.de @poldresden.bsky.social

Great to see this officially out: An mTurquoise2-Based Glucose Biosensor - works in yeast & mammalian cells and is compatible with FLIM: pubs.acs.org/doi/10.1021/...

Little reminder about this paper out there, it's a great reference for anyone working on Flipper-TR experiments! By @chloeroffay.bsky.social @rouxlab.bsky.social

Mammalian cells labeled with lysotracker are perfect for teaching live cell imaging. Minimal preparation, always works, and, as a bonus, results in nice data for #FluorescenceFriday

How do cells orchestrate themselves to achieve a directional movement as a group? Hi, I’m @sayukihirano.bsky.social. In this thread, I’ll highlight key mechanisms of how cells communicate with each other to perform directional collective migration.

Curious if anyone has applied #MCP in materials physics or other scientific fields. Concrete use cases, prototypes, or lessons learned are very welcome. Looking to connect with fellow scientists and exchange experiences in this area. #OpenScience #MaterialsPhysics #Physics #Langchain

AMAZING JOB OPPORTUNITY ALERT!!! @calm-stp.bsky.social is hiring a Data & Systems Steward! 🧬 🔹Manage #bioimage data & #OMERO admin 🔹Automate via #Python/#Bash 🔹Support #FAIR principles 🔹Work closely with @crick-ia-team.bsky.social ⏰ Deadline: 08 Feb 2026 Apply: www.crick.ac.uk/careers-stud...

JCS snapshot - Tracking coordinated cellular dynamics in time-lapse microscopy with ARCOS.px @macdobry.bsky.social presents the key findings from their recent JCS paper with @bgraedel.bsky.social and colleagues @olivierpertz.bsky.social. journals.biologists.com/jcs/article/...

A Comment discusses how commands, data, and metadata currently discarded by scientific instruments could be used to train AI systems to learn to conduct experiments. @henrypinkard.bsky.social @nilsnorlin.bsky.social www.nature.com/articles/s41...