Comprehensive Lineage Tracing Maps the Landscape of Cell Fate Decisions in Mouse Embryogenesis https://www.biorxiv.org/content/10.64898/2026.05.07.722278v1

(1/15) Thrilled to share new Evo-Devo work where we address the molecular, cellular & morphometric basis of an extreme axis segmentation program in the Japanese eel — an animal that forms 120 vertebrae.

EpCAM sustains crypt mechanics and prevents aberrant remodeling https://www.biorxiv.org/content/10.64898/2026.04.27.721034v1

The vertebrate yolk sac: evolutionary origins & current advances in #invitromodels Blagrove & co examine the evolution of the extra-embryonic endoderm, an evolutionarily ancient tissue co-opted to form the yolk sac, & explore how in vitro models are uncovering its biology. doi.org/10.1242/dev....

Don’t miss this free meeting taking place in Paris from the Institut Thematique BCRDE @inserm.fr @sfbd.bsky.social , @fsscr.bsky.social on Cell Plasticity Sept 21, 22. Keynotes talks by Sui Huang (Seattle, WA, USA), Jessica Whited (Boston, MA, USA) itbcrde.inserm.fr/index.php?pa...

The division Physics and Life of the French Physical Society (SFP) organizes its fourth annual meeting in Lyon, July 9th & 10th! Join us and register here: phys-life-2026.sciencesconf.org Abstract submission deadline: May 30th

Excited to announce Physics of Living Matter 19! To be held in Cambridge 24-25th September 2026: www.plm-symposium.org

This year, the annual symposium of my Chaire @college-de-france.fr will be on The Evolution of Developmental Mechanisms. An impressive lineup of speakers and weirds animals, including humans. Free entrance and coffee breaks. Come, have a seat, relax and enjoy the best possible basic science🤘RT🙏

Just published in @science.org 🚀 By controlling how cells align, we show that living nematic tissues can be programmed to generate forces and fold into predictable 3D shapes. A new platform for tissue engineering and the design of smart active materials! 🫆 www.science.org/doi/10.1126/...

#DBfeature #DBreview Quantifying convergent extension: Shih and Keller's quintessential work in developmental cell biology by Robert Huebner, John Wallingford @jbwallingford.bsky.social www.sciencedirect.com/science/arti...

How can we learn tissue mechanics directly from cell patterns and images? In our new preprint, we introduce VertAX, a differentiable vertex-model framework in JAX for simulating epithelia, inferring parameters, and designing target tissue behaviors. shorturl.at/PUzT0 1/5

Physiological architecture and evolutionary origins of cellular adaptability https://www.biorxiv.org/content/10.64898/2026.04.10.717775v1

📢 Registrations are open for the 𝐂𝐄𝐍𝐓𝐔𝐑𝐈 𝐒𝐜𝐢𝐞𝐧𝐭𝐢𝐟𝐢𝐜 𝐌𝐞𝐞𝐭𝐢𝐧𝐠 𝟐𝟎𝟐𝟔! 🗓️ Oct 26–30, 2026 📍Institut d'Études Scientifiques de Cargèse, Corsica Topic: 𝐃𝐚𝐭𝐚-𝐃𝐫𝐢𝐯𝐞𝐧 𝐁𝐢𝐨𝐥𝐨𝐠𝐢𝐜𝐚𝐥 𝐌𝐨𝐝𝐞𝐥𝐢𝐧𝐠 𝐌𝐨𝐫𝐞 𝐢𝐧𝐟𝐨: centuri-livingsystems.org/csm-2026/

evodevmec2026.sciencesconf.org "Roadmap for EvoDevoMec",  Nov. 2nd - 5th, 2026, Université Paris Cité.

🥳 I am happy to share our latest manuscript published in @natcellbio.nature.com We use #Gastruloids to study #CellCompetition during early mammalian development and find not only that this is highly pronounced in our system but also tightly restricted in time. (1/12) www.nature.com/articles/s41...

Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells journals.biologists.com/dev/article/... - what a gorgeous paper this is! (2014 from @amartinezarias.bsky.social and colleagues - introducing 'gastruloids'!)

So excited to share that my 1st paper is published!! Read all about how to manipulate the #MechanicalProperties of tissues using our custom built TiFM! journals.biologists.com/dev/article/...

I'm happy to present our new tool, EpiCure, a napari plugin to ease correction of segmentation and tracking of epithelia movies, developed in @devstempasteur.bsky.social

Briefly, after organ injury, 100 milliseconds, we detected collective changes in membrane potential at the tissue level. This is so far the earliest detected wound-response!! This electric signal sparks the formation of a tissue-wide calcium wave👇

Excited to share our new article, ‘Mechanical regulation of cuboidal-to-squamous epithelial transition in the Drosophila developing wing’, now online in Current Biology. doi.org/10.1016/j.cu... There’s also a great accompanying Dispatch: doi.org/10.1016/j.cu... #MatrixMechanics #DevBio

We are looking for a new group leader to join the IGH (Montpellier, France). I can’t wait to meet my future colleague! Apply :-) More infos here: igh.cnrs.fr/join-igh-as-...

'La science n'est pas une opinion'

Many ion channels eg. TRP, Piezo are mechanically sensitive, meaning they can be activated/deactivated by mechanical stimuli such as membrane curvature or substrate stiffness. In this thorough review from the Mayor lab, they discuss how these channels regulate cell migration. doi.org/10.1016/j.cd...

The I2BC is now accepting applications for new group leader positions. Explore our research at the Institute in our Journal: www.scoop.it/u/institut-d... Deadline: April 22, 2026 @i2bcparissaclay.bsky.social

Hong's @bdyxwh.bsky.social paper is out with help from @sshamphavi.bsky.social and @archaellum.bsky.social. We discovered a link between nuclear actin and YAP/TAZ: G-actin forms a complex with YAP-TEAD for transcription. academic.oup.com/nar/article/...

Reconstituting Mouse Embryogenesis Ex Utero from Gastrulation to Fetal Development Reveals Maternally Independent Metabolic Programs https://www.biorxiv.org/content/10.64898/2026.03.17.710314v1

We are excited to be recruiting into 3 Associate Professorship's in @oxfordbiochemistry.bsky.social. Come join us as a colleague and benefit from our vibrant and multidisciplinary environment. Reach out to me if you have any questions. Please repost! (tinyurl.com/48deybuu) (tinyurl.com/4pdvjaft).

The @gdraqv.bsky.social "Approches Quantitatives du Vivant" is organizing its annual conference, "AQV Days 2026". 🗓️ From the 11th to 13th May 📍 At the @cnrs.fr centre of Aussois (Savoie) 👉 registration, and other practical information : 🔗 aqv-days-2026.sciencesconf.org/%60 #AQVDays2026

3/5 Mapping the Invisible: Using Flipper-TR + FLIM imaging, researchers visualized tension in live lung tissue. They discovered a drop in membrane tension before cells differentiate into AT1 or AT2 alveolar cells. Even cooler? It mapped "emergent zones" of low tension where differentiation starts!

First 24 hours of embryonic development in 9 different animal species: (From left to right) Zebrafish, Sea urchin, Black widow spider, Tardigrade, Sea squirt, Comb jelly, Parchment tube worm, Roundworm, Slipper snail. Credit to @tessamontague.bsky.social & Zuzka Vavrušová. #ZebrafishZunday #devbio 🧪

🚨 #postdoc to be hired in the Paluch Lab 🚨 If you know anyone experienced with and, more importantly, excited about nanoscale architecture of #actincortex and super-res & electron #microscopy do encourage them to apply👇 Amazing colleagues, can only recommend 😉 www.cam.ac.uk/jobs/researc...

New from @dev-journal.bsky.social: we're launching a new initiative and hiring Preprint Editors to help navigate the growing world of preprints in developmental & stem cell biology Join our community & shape the future of research journals.biologists.com/dev/article/...

Stretching drives Membrane Homogenization of Phase-Separated Supported Lipid Bilayers https://www.biorxiv.org/content/10.64898/2026.02.26.708304v1

New preprint @biorxiv-devbio.bsky.social by Harshath Amal and colleagues from our lab @uni-muenster.de shows how a BMP #morphogen gradient is translated into graded junctional permeability by tuning adhesion and actomyosin contractility in #Drosophila See tinyurl.com/yhbwd9xh @sfb1348.bsky.social

Avec Guillaume Dera, premier auteur de l'étude. www.science.org/doi/10.1126/...

Des bactéries aux arbres, des coraux aux oiseaux, la vie terrestre semble d’une diversité infinie. Pourtant, une nouvelle étude montre que le vivant n’explore qu’une infime fraction des formes théoriquement possibles. 🦌🐊🌴🐠🐌 (et oui, j'ai passé le Roi Lion à la fin, faut savoir se faire plaisir)

We‘re looking for a motivated Master student to join our team! Do you want to optogenetically control metabolic activity to see how metabolism affects patterning and morphogenesis? 💡🧫🧬🔬 Then please apply! #optogenetics #metabolism #devbio #hESCs Please RT. Thank you!🙏

📄 In cells, osmotic shocks shift Flipper-TR lifetime consistently with increased or decreased membrane tension, provided composition is controlled. This paper also compared quantitatively tether force and F-TR lifetime measurements @chloeroffay.bsky.social 🔗 bsky.app/profile/epim...

interesting read😯 www.cell.com/cell/abstrac...

Advanced grad students + postdocs: apply for the 2026 #kitpqbio summer course, "Physical Principles of Morphogenesis in Plants and Animals," at buff.ly/OXXMKEv. Apply by Feb. 1. Course directors Adrienne Roeder (Cornell) and Sebastian Streichan (UCSB)

@marineluciano.bsky.social recreates intestinal Villi geometry by growing epithelial cells on wavy rolling substrates. Unexpected intrication of curvature effects is observed. Thanks to all! @caterinatomba.bsky.social @sgabriele.bsky.social @sciencesunige.bsky.social www.biorxiv.org/content/10.6...

😂😂

📢 Open faculty position – Origins of Life We have an opening in our section at the University of Geneva! 🧬🚀 SPREAD THE WORD Apply here: jobs.unige.ch/www/wd_porta...

Feb 1 deadline approaching for our @kitp-ucsb.bsky.social QBio summer course on Physical Principles of Morphogenesis in Plants and Animals. @streichan.bsky.social @maurazimmermann.bsky.social @maizel-lab.org @yusuke-mori.bsky.social @akankshi.bsky.social @nicolettapetridou.bsky.social

*HELP* Someone found how to include *avis de personnalités* in the @cnrs.fr website for the Concours chercheurs? Thanks, I have nothing to offer, Austria does not have galette des rois

Lipid-mediated reinforcement of FGF/MAPK signaling enables robust otic placode specification https://www.biorxiv.org/content/10.64898/2026.01.06.698011v1

Genetically engineered ESC-derived embryos reveal Vinculin-dependent force responses required for mammalian neural tube closure https://www.biorxiv.org/content/10.64898/2025.12.22.696028v1

Can biological tissues "learn"? Our new preprint shows that epithelial tissues exhibit emergent behaviors akin to unsupervised learning. Local tension remodeling allows cell networks to store long-range memory and program global elasticity properties. Read more here: www.biorxiv.org/content/10.6...

This movie shows lysosomes (orange) and keratin (gray) in a cultured cell over 10 minutes.