Alejandro Torres-Sánchez
@torres-sanchez.bsky.social
📤 585
📥 494
📝 17
Physicist trying to understand the behaviour of living organisms. Group leader at EMBL Barcelona.
pinned post!
Imagine being an engineer asked to build a material that withstands 100% strain, 150 times per minute—for a lifetime. Now imagine having to build it while it’s already functioning. That’s exactly what the heart does.
add a skeleton here at some point
over 1 year ago
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EMBL
5 days ago
Congratulations, Anna Erzberger! The EMBL Group Leader has received the Inaugural Suzanne Eaton ‘Rising Star’ Award for Physics of Life in 2026, presented by
@poldresden.bsky.social
. Learn more:
www.embl.org/news/awards-...
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Alejandro Torres-Sánchez
Lena Schindler
6 days ago
I am thrilled to share my PhD work with
@nicolettapetridou.bsky.social
@embl.org
:
www.biorxiv.org/cgi/content/...
A fun collaboration with Bernat Corominas-Murtra, Adrián Aguirre-Tamaral,
@bart-smeets.bsky.social
, Jef Vanghel and Tom Belpaire! Read the story in the comments below ⤵️
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Mike Dorrity
10 days ago
First pre-print from the lab, a collaborative effort led by Jess Bourn
@bournsupremacy.bsky.social
, a fantastic PhD in my group. We resolve a key problem in development + evolution: how do we quantify heterochrony and link temporal variation to phenotype?
www.biorxiv.org/content/10.6...
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Quantitative mapping of heterochrony to species-specific phenotypes
The genetic program of animal development is conserved, but its rate of execution varies across species. Heterochrony, shifts in the relative timing of developmental events, generates phenotypic varia...
https://www.biorxiv.org/content/10.64898/2026.06.15.732302v1
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Alison Kickuth
11 days ago
I am honoured to have received the Otto Hahn Medal! Thank you Jan
@brugueslab.bsky.social
,
@ursa-ursic.bsky.social
, Michael Staddon,
@mpi-cbg.de
, and
@poldresden.bsky.social
for your support during this scientific journey!
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James Briscoe
21 days ago
Our latest: Minimal essential requirements for neural tube self-organisation How does a single cell give rise to a tissue with the right cell types in the right proportions? We deconstruct and rebuild a self-organising tissue from first principles A thread🧵
www.biorxiv.org/content/10.6...
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Minimal essential requirements for neural tube self-organisation
The reliable generation of diverse cell types in precise proportions is essential for the formation of functional tissues during embryonic development. Three-dimensional organoid models derived from p...
https://www.biorxiv.org/content/10.64898/2026.06.06.730555v1
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Nimesh Chahare
about 1 month ago
How does a relatively simple tube become a complex brain? 🧠 One of the most dramatic transformations in development! We built a framework to map exactly what changes. 🧵 New preprint from my postdoc at
@nerurkar.bsky.social
lab:
doi.org/10.64898/202...
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Alejandro Torres-Sánchez
Hiscock Lab
about 1 month ago
🚨Job alert in theory/math devbio 🚨 I’m currently advertising postdoc positions to join my group. We’re building reaction-diffusion models to understand some of the amazing things embryos can do. We are based in a beautiful part of Scotland! Please share!
www.abdn.ac.uk/jobs/vacanci...
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Alejandro Torres-Sánchez
Nicoletta Petridou
about 1 month ago
Glad to see this out in its final form!
www.nature.com/articles/s41...
What changed since the preprint? Wonderful experiments disentangling the effect of receptor binding vs tissue porosity on Nodal diffusion, plus one of the smoothest review experiences! Thanks
@natcellbio.nature.com
& reviewers 🙏
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Turlier lab
2 months ago
A real computational tour de force by @ericneiva.bsky.social, carried out as Marie Skłodowska-Curie postdoctoral fellow in the team, now published in the Journal of Computational Physics:
urlr.me/AuzK86
Congratulations, Eric!
@cnrsbiologie.bsky.social
Grateful to
@ec.europa.eu
for funding support
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Aissam Ikmi
2 months ago
Now published. Congrats to Soham and all co-authors!
www.science.org/doi/10.1126/...
.
@embl.org
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Xavier Trepat
2 months ago
Our latest work on shape-programmable tissues is out in
@science.org
. By positioning topological defects in cellular nematics, we encode frustrated 2D force fields that relax into predictable 3D shapes. Collaboration with Marino Arroyo’s lab, led by
@pauguillamat.bsky.social
at
@ibecbarcelona.eu
.
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Pau Guillamat
2 months ago
Just published in
@science.org
🚀 By controlling how cells align, we show that living nematic tissues can be programmed to generate forces and fold into predictable 3D shapes. A new platform for tissue engineering and the design of smart active materials!
www.science.org/doi/10.1126/...
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EMBL
2 months ago
Congratulations to Vikas Trivedi & collaborators for being awarded the HFSP grant! An international team coordinated by EMBL Barcelona researchers has been awarded $1.5M to study how developing organisms stay on track despite climate-driven temperature instability.
www.embl.org/news/awards-...
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New funding to explore how embryos survive temperature stress in the era of climate change | EMBL
An international team coordinated by Vikas Trivedi at EMBL Barcelona has been awarded an HFSP grant worth $1.5 million (€1.3 M) to study how developing organisms stay on track despite climate-driven t...
https://www.embl.org/news/awards-honours/new-funding-to-explore-how-embryos-survive-temperature-stress-in-the-era-of-climate-change/
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Amayra Hernández Vega
3 months ago
We are hiring! Come work with us in sunny Barcelona. We are looking for a Postdoctoral Researcher to study neuronal degeneration in Alzheimer’s Disease. Please help spread the word, and feel free to contact me if you have any questions.
ibecbarcelona.eu/postdoctoral...
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Postdoctoral Researcher at the Molecular Bionics Research Group (Neuronal Degeneration in Alzheimer’s Disease Project) - Institute for Bioengineering of Catalonia
PR-AH // Deadline: 30/04/2026
https://ibecbarcelona.eu/postdoctoral-researcher-at-the-molecular-bionics-research-group-neuronal-degeneration-in-alzheimers-disease-project/
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Kristina Stapornwongkul
3 months ago
The
@vbcscitraining.bsky.social
is looking a PhD Program Manager! Needless to say this is an incredible important position. So please apply if you want to help us find, recruit and train the next generation of scientists! RT appreciated!
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Zebrafish Rock!
3 months ago
Finished your PhD & looking for a Postdoc position? Intrigued by
#zebrafish
heart morphogenesis? Job available in the
@rashmi-priya.bsky.social
Lab at
@crick.ac.uk
(Initial 4 years funding w/ potential for 2 additional years)🐟❤️ More details:
crick.wd3.myworkdayjobs.com/External/job...
Please share 🧪
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Kristina Stapornwongkul
3 months ago
We’re looking for a new team member! 🚀 Only 3 more weeks to apply to the fantastic Vienna BioCenter PhD program
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Alejandro Torres-Sánchez
Cell - a Cell Press journal
3 months ago
Now online! Deciphering mechanical determinants of morphological evolution
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Deciphering mechanical determinants of morphological evolution
A comparative analysis of cnidarian larval morphogenesis combined with active surface theory identifies a set of mesoscale mechanical modules that predict species-specific shapes. Manipulating these modules reprograms morphology, revealing how variation in tissue-scale mechanics underlies morphological diversity.
http://dlvr.it/TRc1kn
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Aissam Ikmi
3 months ago
Our study on shape diversity in cnidarians is now published. The final version includes extensive new data that substantially extend the original bioRxiv preprint. Congrats to everyone who contributed to this work!
www.cell.com/cell/fulltex...
@embl.org
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Alex Eve
4 months ago
Planarians also reproduce asexually by fission – pulling their body in two & then regenerating the missing halves. Breaking occurs all over development; see this recent
@dev-journal.bsky.social
Review from
@torres-sanchez.bsky.social
,
@rashmi-priya.bsky.social
& colleagues:
doi.org/10.1242/dev....
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Kristina Stapornwongkul
4 months ago
Are you fascinated by self-organised patterning processes? The brand-new Stuart lab at EMBL Barcelona is looking for a lab manager! Hannah
@htstuart.bsky.social
is a fantastic scientist and mentor. Building the lab with her will be a lot of fun!
embl.wd103.myworkdayjobs.com/EMBL/job/Bar...
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Lab Manager - Stuart Group
The European Molecular Biology Laboratory (EMBL) is one of the world’s leading life science research organisations. With sites across Europe, EMBL fosters an international, collaborative, and inclusiv...
https://embl.wd103.myworkdayjobs.com/EMBL/job/Barcelona/Lab-Manager---Stuart-Group_JR2656
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Katie Pickup
4 months ago
Really interesting article about fracture in developing tissues. For a deep dive into examples across species, you can also check out
@rashmi-priya.bsky.social
and
@torres-sanchez.bsky.social
's recent Review in Development
@dev-journal.bsky.social
⬇️
journals.biologists.com/dev/article/...
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Alejandro Torres-Sánchez
Quanta Magazine
4 months ago
“In biology, breaking isn’t always a failure,” said the developmental biologist Rashmi Priya (right). “It’s often a necessary step in building something new.”
www.quantamagazine.org/break-it-to-...
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Alejandro Torres-Sánchez
epithelial mechanics fan club
4 months ago
We had covered the history of traction force microscopy (TFM) earlier:
bsky.app/profile/epim...
But what about applying TFM into more physiologically relevant systems, such as those in 3D? I am
@barrasa-fano.bsky.social
and I'll be your guide through this thread on
#3DTractionForceMicroscopy
.
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Alejandro Torres-Sánchez
Quanta Magazine
4 months ago
Sometimes, the only way to build back up is to let everything fall apart. This is certainly true at the cellular level.
www.quantamagazine.org/break-it-to-...
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Break It To Make It: How Fracturing Sculpts Tissues and Organs | Quanta Magazine
Growing tissues can crack, break, and dissociate to form structures that can later withstand immense forces.
https://www.quantamagazine.org/break-it-to-make-it-how-fracturing-sculpts-tissues-and-organs-20260227/
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Leone Rossetti
4 months ago
Interested in a PhD in collective cell migration & mechanobiology? I'm looking to support a candidate applying for a fully funded UK/Home PhD. The project studies the biophysics of migrating cells, using force measurements & optogenetics, with collaborators in Japan.
#mechanobiology
#PhD
eb4bm.org
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Home - Engineering Biology For Biomedicine
Engineering Biology for Biomedicine A UKRI:BBSRC Centre for doctoral training Why EB4BM “ Our graduates bridge fundamental biological design principles with biomedical bottlenecks, delivering engineer...
https://eb4bm.org/
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Alejandro Torres-Sánchez
Carlos Pérez-González
4 months ago
I’m thrilled to share that I will join
@gustaveroussy.fr
as a Group Leader! Our objective: to understand how mechanochemical feedbacks regulate tumor dynamics and plasticity, with the overarching goal of bridging tissue mechanobiology and tumor pathophysiology using human organoids.
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Laura Rustarazo-Calvo
4 months ago
Excited to share our new review in
@dev-journal.bsky.social
on tissue phase transitions during development!
@karengrace12.bsky.social
@nicolettapetridou.bsky.social
🔗
doi.org/10.1242/dev....
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Tissue phase transitions in development: more than just mechanics
Summary: Tissue material phase transitions are classically thought to regulate tissue deformability. This Review emphasises their unexpected roles in directly influencing growth and patterning signall...
https://doi.org/10.1242/dev.205219
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EMBL
4 months ago
Our cells are experts at navigating inherently noisy and complicated environments. EMBL researchers are using theoretical physics approaches to uncover fundamental principles behind how cells use complex information to self-organise.
www.embl.org/news/science...
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Kristina Stapornwongkul
4 months ago
We‘re looking for a motivated Master student to join our team! Do you want to optogenetically control metabolic activity to see how metabolism affects patterning and morphogenesis? 💡🧫🧬🔬 Then please apply!
#optogenetics
#metabolism
#devbio
#hESCs
Please RT. Thank you!🙏
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Development builds... But it also breaks! Planarians split to reproduce. Hydra tears open a mouth. Embryos fracture to make cavities. Failure? No. Fracture is essential to development. Our new review on fracture physics and its uses in development:
journals.biologists.com/dev/article/...
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5 months ago
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Doug Aoki
5 months ago
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Alejandro Torres-Sánchez
Brugues Lab
6 months ago
Excited to share Alison's
@alisonkickuth.bsky.social
paper from the lab out in
@nature.com
this week! We uncovered how a mechanical ratchet mechanism drives cytokinesis in early
#zebrafish
embryos. Read more in this thread 🧵 and at
www.nature.com/articles/s41...
🤩
@poldresden.bsky.social
@mpi-cbg.de
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Pierre-François Lenne
6 months ago
Interested in the biophysics of organoids? We just published a review in Dev Cell—take a look!
dlvr.it/TPyTb8
#Organoids
#Biophysics
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Biophysics of organoids
In this review, Weichselberger, Moore et al. discuss how physics-based approaches illuminate organoid development and homeostasis by integrating mechanical, chemical, and informational processes. They...
http://dlvr.it/TPyTb8
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Marco MILAN LAB
6 months ago
elpais.com/ciencia/2026...
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El pastelero que patentó una molécula contra el cáncer que se ha vendido por 7.000 millones de euros
El biólogo Eduard Batlle, criado en la pastelería de sus padres, es uno de los seis inventores del petosemtamab, un revolucionario tratamiento experimental contra los tumores
https://elpais.com/ciencia/2026-01-04/el-pastelero-que-patento-una-molecula-contra-el-cancer-que-se-ha-vendido-por-7000-millones-de-euros.html
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Alejandro Torres-Sánchez
Adam Rutherford
6 months ago
Empire. Oil. Guyana.
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Alejandro Torres-Sánchez
Development
6 months ago
Transitions in development – an interview with Alejandro Torres-Sánchez We caught up with Alejandro
@torres-sanchez.bsky.social
from
@embl.org
Barcelona to talk about his path to becoming a group leader, ongoing collaborations and addressing gender imbalance in the lab.
doi.org/10.1242/dev....
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Alejandro Torres-Sánchez
Guillaume Charras
6 months ago
How does signalling control cortical tension? Using optogenetics and AFM, we show that myosin recruitment and cortical tension increase proportionally with RhoA signalling. More here:
www.biorxiv.org/content/10.6...
Super work by Pierre Bohec with Guillaume Salbreux and
@dianakhorom.bsky.social
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Agathe Chaigne
6 months ago
My lab is hiring a postdoc (ERC funded)! If you're interested, get in touch!
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youtu.be/JUCs_JEl5bY?...
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|Extrechinato y tu| Abrazado a la tristeza
YouTube video by XtremayDura
https://youtu.be/JUCs_JEl5bY?si=b2_MQGIFxkDOVPhI
7 months ago
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Alejandro Torres-Sánchez
EMBL
7 months ago
Researchers at EMBL Barcelona have launched LimbNET, a new online platform that integrates computer modeling, experimental data, and 2D live simulations for limb development.
www.embl.org/news/science...
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Alejandro Torres-Sánchez
Maria Bernabeu
7 months ago
Come to Biomalpar xxii!!! We have an outstanding line up of speakers!!! It is a true honor to be an organizer of Biomalpar. It was the first conference I ever attended during my 2nd PhD year so it feels special. And don't miss the beautiful poster image from Hannah Fleckenstein!
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Wolfgang Huber
7 months ago
Join EMBL's Interdisciplinary Postdoc Programme! 3 years funding, self-designed interdisciplinary project co-led between EMBL PI and PI in one of EMBL's actual, prospect or associate member states. In particular: AI&Theory, use mathem. models, physics principles and AI
www.embl.org/about/info/p...
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EIPOD-LinC Fellowship Programme – Postdoctoral Programme
https://www.embl.org/about/info/postdoctoral-programme/eipod-linc-exploring-life-in-context/
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Alejandro Torres-Sánchez
epithelial mechanics fan club
7 months ago
It’s time to talk about epithelial geometry and cancer. How can the architecture of an epithelium affect how tumors will grow and spread? In this thread,
@jorgealmagro.bsky.social
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Ulrich Schwarz
7 months ago
📢 Paper alert 📢 Chirality is known to be important for the movement of microorganisms and active matter. In our new paper out today in
@natphys.nature.com
, we show that chirality is used by malaria parasites to control their motion patterns:
doi.org/10.1038/s415...
Here comes a 🧵 ... (1/9)
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Alejandro Torres-Sánchez
7 months ago
1/ Cerebral malaria is a severe form of malaria that causes damage to the blood vessels in the brain. With a #HealthResearch grant,
@mariabernabeu.bsky.social
#HealthResearch
uses analytical techniques and human 3D models of blood vessels to ⬆️ our understanding and test new therapies.
https://tinyurl.com/2vtjnwn6
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Alejandro Torres-Sánchez
epithelial mechanics fan club
8 months ago
Which features of tissue flows are most robust and how do they emerge from
#EpithelialMechanics
? I’m
@alex-plum.bsky.social
(
@mattiaserra.bsky.social
group) and I’ll be sharing some papers on characterizing and controlling avian gastrulation flows.
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Institute of Molecular Biotechnology
8 months ago
In our latest interview, Kristina Stapornwongkul, the newest group leader at IMBA, shares her journey to joining the institute, why she chose IMBA as the next step in her career, and her vision for her lab exploring how metabolism shapes embryonic development:
https://imba.science/49fCrxl
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Alejandro Torres-Sánchez
Xavier Trepat
8 months ago
📣Announcing the 4th edition of the EMBL‑IBEC Conference on “Engineering Multicellular Systems”, taking place 11–13 March 2026 in Barcelona. Exploring organoids, mechanobiology, embryo models, organ-on-chip systems, multiomics and more. Abstracts open now!
events.ibecbarcelona.eu/embl-ibec-co...
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Alejandro Torres-Sánchez
Maria Bernabeu
8 months ago
Pre-print alert 🚨 We answer a longstanding question in the field. Do immune cells cause cerebral malaria? The answer is YES!!!! And independently of P. falciparum accumulation in the brain.
www.biorxiv.org/cgi/content/...
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Innate immune responses to Plasmodium falciparum disrupt the blood-brain barrier
Plasmodium falciparum accumulation at the blood-brain barrier (BBB) is a hallmark of cerebral malaria, a life-threatening complication. Conversely, the contribution of the immune response to vascular ...
https://www.biorxiv.org/cgi/content/short/2025.10.20.683440v1
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