Alejandro Torres-Sánchez
@torres-sanchez.bsky.social
📤 582
📥 492
📝 17
Physicist trying to understand the behaviour of living organisms. Group leader at EMBL Barcelona.
pinned post!
Imagine being an engineer asked to build a material that withstands 100% strain, 150 times per minute—for a lifetime. Now imagine having to build it while it’s already functioning. That’s exactly what the heart does.
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about 1 year ago
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Turlier lab
22 days ago
A real computational tour de force by @ericneiva.bsky.social, carried out as Marie Skłodowska-Curie postdoctoral fellow in the team, now published in the Journal of Computational Physics:
urlr.me/AuzK86
Congratulations, Eric!
@cnrsbiologie.bsky.social
Grateful to
@ec.europa.eu
for funding support
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Aissam Ikmi
24 days ago
Now published. Congrats to Soham and all co-authors!
www.science.org/doi/10.1126/...
.
@embl.org
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Xavier Trepat
25 days ago
Our latest work on shape-programmable tissues is out in
@science.org
. By positioning topological defects in cellular nematics, we encode frustrated 2D force fields that relax into predictable 3D shapes. Collaboration with Marino Arroyo’s lab, led by
@pauguillamat.bsky.social
at
@ibecbarcelona.eu
.
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Pau Guillamat
26 days ago
Just published in
@science.org
🚀 By controlling how cells align, we show that living nematic tissues can be programmed to generate forces and fold into predictable 3D shapes. A new platform for tissue engineering and the design of smart active materials!
www.science.org/doi/10.1126/...
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EMBL
27 days ago
Congratulations to Vikas Trivedi & collaborators for being awarded the HFSP grant! An international team coordinated by EMBL Barcelona researchers has been awarded $1.5M to study how developing organisms stay on track despite climate-driven temperature instability.
www.embl.org/news/awards-...
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New funding to explore how embryos survive temperature stress in the era of climate change | EMBL
An international team coordinated by Vikas Trivedi at EMBL Barcelona has been awarded an HFSP grant worth $1.5 million (€1.3 M) to study how developing organisms stay on track despite climate-driven t...
https://www.embl.org/news/awards-honours/new-funding-to-explore-how-embryos-survive-temperature-stress-in-the-era-of-climate-change/
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Amayra Hernández Vega
29 days ago
We are hiring! Come work with us in sunny Barcelona. We are looking for a Postdoctoral Researcher to study neuronal degeneration in Alzheimer’s Disease. Please help spread the word, and feel free to contact me if you have any questions.
ibecbarcelona.eu/postdoctoral...
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Postdoctoral Researcher at the Molecular Bionics Research Group (Neuronal Degeneration in Alzheimer’s Disease Project) - Institute for Bioengineering of Catalonia
PR-AH // Deadline: 30/04/2026
https://ibecbarcelona.eu/postdoctoral-researcher-at-the-molecular-bionics-research-group-neuronal-degeneration-in-alzheimers-disease-project/
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Kristina Stapornwongkul
about 1 month ago
The
@vbcscitraining.bsky.social
is looking a PhD Program Manager! Needless to say this is an incredible important position. So please apply if you want to help us find, recruit and train the next generation of scientists! RT appreciated!
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Zebrafish Rock!
about 2 months ago
Finished your PhD & looking for a Postdoc position? Intrigued by
#zebrafish
heart morphogenesis? Job available in the
@rashmi-priya.bsky.social
Lab at
@crick.ac.uk
(Initial 4 years funding w/ potential for 2 additional years)🐟❤️ More details:
crick.wd3.myworkdayjobs.com/External/job...
Please share 🧪
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Kristina Stapornwongkul
about 2 months ago
We’re looking for a new team member! 🚀 Only 3 more weeks to apply to the fantastic Vienna BioCenter PhD program
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Cell - a Cell Press journal
about 2 months ago
Now online! Deciphering mechanical determinants of morphological evolution
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Deciphering mechanical determinants of morphological evolution
A comparative analysis of cnidarian larval morphogenesis combined with active surface theory identifies a set of mesoscale mechanical modules that predict species-specific shapes. Manipulating these modules reprograms morphology, revealing how variation in tissue-scale mechanics underlies morphological diversity.
http://dlvr.it/TRc1kn
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Aissam Ikmi
about 2 months ago
Our study on shape diversity in cnidarians is now published. The final version includes extensive new data that substantially extend the original bioRxiv preprint. Congrats to everyone who contributed to this work!
www.cell.com/cell/fulltex...
@embl.org
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Alex Eve
2 months ago
Planarians also reproduce asexually by fission – pulling their body in two & then regenerating the missing halves. Breaking occurs all over development; see this recent
@dev-journal.bsky.social
Review from
@torres-sanchez.bsky.social
,
@rashmi-priya.bsky.social
& colleagues:
doi.org/10.1242/dev....
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Kristina Stapornwongkul
2 months ago
Are you fascinated by self-organised patterning processes? The brand-new Stuart lab at EMBL Barcelona is looking for a lab manager! Hannah
@htstuart.bsky.social
is a fantastic scientist and mentor. Building the lab with her will be a lot of fun!
embl.wd103.myworkdayjobs.com/EMBL/job/Bar...
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Lab Manager - Stuart Group
The European Molecular Biology Laboratory (EMBL) is one of the world’s leading life science research organisations. With sites across Europe, EMBL fosters an international, collaborative, and inclusiv...
https://embl.wd103.myworkdayjobs.com/EMBL/job/Barcelona/Lab-Manager---Stuart-Group_JR2656
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Katie Pickup
2 months ago
Really interesting article about fracture in developing tissues. For a deep dive into examples across species, you can also check out
@rashmi-priya.bsky.social
and
@torres-sanchez.bsky.social
's recent Review in Development
@dev-journal.bsky.social
⬇️
journals.biologists.com/dev/article/...
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Quanta Magazine
2 months ago
“In biology, breaking isn’t always a failure,” said the developmental biologist Rashmi Priya (right). “It’s often a necessary step in building something new.”
www.quantamagazine.org/break-it-to-...
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epithelial mechanics fan club
2 months ago
We had covered the history of traction force microscopy (TFM) earlier:
bsky.app/profile/epim...
But what about applying TFM into more physiologically relevant systems, such as those in 3D? I am
@barrasa-fano.bsky.social
and I'll be your guide through this thread on
#3DTractionForceMicroscopy
.
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Quanta Magazine
2 months ago
Sometimes, the only way to build back up is to let everything fall apart. This is certainly true at the cellular level.
www.quantamagazine.org/break-it-to-...
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Break It To Make It: How Fracturing Sculpts Tissues and Organs | Quanta Magazine
Growing tissues can crack, break, and dissociate to form structures that can later withstand immense forces.
https://www.quantamagazine.org/break-it-to-make-it-how-fracturing-sculpts-tissues-and-organs-20260227/
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Leone Rossetti
2 months ago
Interested in a PhD in collective cell migration & mechanobiology? I'm looking to support a candidate applying for a fully funded UK/Home PhD. The project studies the biophysics of migrating cells, using force measurements & optogenetics, with collaborators in Japan.
#mechanobiology
#PhD
eb4bm.org
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Home - Engineering Biology For Biomedicine
Engineering Biology for Biomedicine A UKRI:BBSRC Centre for doctoral training Why EB4BM “ Our graduates bridge fundamental biological design principles with biomedical bottlenecks, delivering engineer...
https://eb4bm.org/
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Carlos Pérez-González
3 months ago
I’m thrilled to share that I will join
@gustaveroussy.fr
as a Group Leader! Our objective: to understand how mechanochemical feedbacks regulate tumor dynamics and plasticity, with the overarching goal of bridging tissue mechanobiology and tumor pathophysiology using human organoids.
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Laura Rustarazo-Calvo
3 months ago
Excited to share our new review in
@dev-journal.bsky.social
on tissue phase transitions during development!
@karengrace12.bsky.social
@nicolettapetridou.bsky.social
🔗
doi.org/10.1242/dev....
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Tissue phase transitions in development: more than just mechanics
Summary: Tissue material phase transitions are classically thought to regulate tissue deformability. This Review emphasises their unexpected roles in directly influencing growth and patterning signall...
https://doi.org/10.1242/dev.205219
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EMBL
3 months ago
Our cells are experts at navigating inherently noisy and complicated environments. EMBL researchers are using theoretical physics approaches to uncover fundamental principles behind how cells use complex information to self-organise.
www.embl.org/news/science...
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Kristina Stapornwongkul
3 months ago
We‘re looking for a motivated Master student to join our team! Do you want to optogenetically control metabolic activity to see how metabolism affects patterning and morphogenesis? 💡🧫🧬🔬 Then please apply!
#optogenetics
#metabolism
#devbio
#hESCs
Please RT. Thank you!🙏
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Development builds... But it also breaks! Planarians split to reproduce. Hydra tears open a mouth. Embryos fracture to make cavities. Failure? No. Fracture is essential to development. Our new review on fracture physics and its uses in development:
journals.biologists.com/dev/article/...
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3 months ago
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Doug Aoki
3 months ago
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Brugues Lab
4 months ago
Excited to share Alison's
@alisonkickuth.bsky.social
paper from the lab out in
@nature.com
this week! We uncovered how a mechanical ratchet mechanism drives cytokinesis in early
#zebrafish
embryos. Read more in this thread 🧵 and at
www.nature.com/articles/s41...
🤩
@poldresden.bsky.social
@mpi-cbg.de
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Pierre-François Lenne
4 months ago
Interested in the biophysics of organoids? We just published a review in Dev Cell—take a look!
dlvr.it/TPyTb8
#Organoids
#Biophysics
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Biophysics of organoids
In this review, Weichselberger, Moore et al. discuss how physics-based approaches illuminate organoid development and homeostasis by integrating mechanical, chemical, and informational processes. They...
http://dlvr.it/TPyTb8
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Marco MILAN LAB
4 months ago
elpais.com/ciencia/2026...
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El pastelero que patentó una molécula contra el cáncer que se ha vendido por 7.000 millones de euros
El biólogo Eduard Batlle, criado en la pastelería de sus padres, es uno de los seis inventores del petosemtamab, un revolucionario tratamiento experimental contra los tumores
https://elpais.com/ciencia/2026-01-04/el-pastelero-que-patento-una-molecula-contra-el-cancer-que-se-ha-vendido-por-7000-millones-de-euros.html
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Adam Rutherford
4 months ago
Empire. Oil. Guyana.
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Development
5 months ago
Transitions in development – an interview with Alejandro Torres-Sánchez We caught up with Alejandro
@torres-sanchez.bsky.social
from
@embl.org
Barcelona to talk about his path to becoming a group leader, ongoing collaborations and addressing gender imbalance in the lab.
doi.org/10.1242/dev....
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Guillaume Charras
5 months ago
How does signalling control cortical tension? Using optogenetics and AFM, we show that myosin recruitment and cortical tension increase proportionally with RhoA signalling. More here:
www.biorxiv.org/content/10.6...
Super work by Pierre Bohec with Guillaume Salbreux and
@dianakhorom.bsky.social
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Agathe Chaigne
5 months ago
My lab is hiring a postdoc (ERC funded)! If you're interested, get in touch!
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youtu.be/JUCs_JEl5bY?...
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|Extrechinato y tu| Abrazado a la tristeza
YouTube video by XtremayDura
https://youtu.be/JUCs_JEl5bY?si=b2_MQGIFxkDOVPhI
5 months ago
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EMBL
5 months ago
Researchers at EMBL Barcelona have launched LimbNET, a new online platform that integrates computer modeling, experimental data, and 2D live simulations for limb development.
www.embl.org/news/science...
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Maria Bernabeu
5 months ago
Come to Biomalpar xxii!!! We have an outstanding line up of speakers!!! It is a true honor to be an organizer of Biomalpar. It was the first conference I ever attended during my 2nd PhD year so it feels special. And don't miss the beautiful poster image from Hannah Fleckenstein!
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Wolfgang Huber
5 months ago
Join EMBL's Interdisciplinary Postdoc Programme! 3 years funding, self-designed interdisciplinary project co-led between EMBL PI and PI in one of EMBL's actual, prospect or associate member states. In particular: AI&Theory, use mathem. models, physics principles and AI
www.embl.org/about/info/p...
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EIPOD-LinC Fellowship Programme – Postdoctoral Programme
https://www.embl.org/about/info/postdoctoral-programme/eipod-linc-exploring-life-in-context/
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epithelial mechanics fan club
6 months ago
It’s time to talk about epithelial geometry and cancer. How can the architecture of an epithelium affect how tumors will grow and spread? In this thread,
@jorgealmagro.bsky.social
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Ulrich Schwarz
6 months ago
📢 Paper alert 📢 Chirality is known to be important for the movement of microorganisms and active matter. In our new paper out today in
@natphys.nature.com
, we show that chirality is used by malaria parasites to control their motion patterns:
doi.org/10.1038/s415...
Here comes a 🧵 ... (1/9)
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6 months ago
1/ Cerebral malaria is a severe form of malaria that causes damage to the blood vessels in the brain. With a #HealthResearch grant,
@mariabernabeu.bsky.social
#HealthResearch
uses analytical techniques and human 3D models of blood vessels to ⬆️ our understanding and test new therapies.
https://tinyurl.com/2vtjnwn6
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Alejandro Torres-Sánchez
epithelial mechanics fan club
6 months ago
Which features of tissue flows are most robust and how do they emerge from
#EpithelialMechanics
? I’m
@alex-plum.bsky.social
(
@mattiaserra.bsky.social
group) and I’ll be sharing some papers on characterizing and controlling avian gastrulation flows.
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Institute of Molecular Biotechnology
7 months ago
In our latest interview, Kristina Stapornwongkul, the newest group leader at IMBA, shares her journey to joining the institute, why she chose IMBA as the next step in her career, and her vision for her lab exploring how metabolism shapes embryonic development:
https://imba.science/49fCrxl
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Xavier Trepat
7 months ago
📣Announcing the 4th edition of the EMBL‑IBEC Conference on “Engineering Multicellular Systems”, taking place 11–13 March 2026 in Barcelona. Exploring organoids, mechanobiology, embryo models, organ-on-chip systems, multiomics and more. Abstracts open now!
events.ibecbarcelona.eu/embl-ibec-co...
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Maria Bernabeu
7 months ago
Pre-print alert 🚨 We answer a longstanding question in the field. Do immune cells cause cerebral malaria? The answer is YES!!!! And independently of P. falciparum accumulation in the brain.
www.biorxiv.org/cgi/content/...
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Innate immune responses to Plasmodium falciparum disrupt the blood-brain barrier
Plasmodium falciparum accumulation at the blood-brain barrier (BBB) is a hallmark of cerebral malaria, a life-threatening complication. Conversely, the contribution of the immune response to vascular ...
https://www.biorxiv.org/cgi/content/short/2025.10.20.683440v1
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Zebrafish Rock!
7 months ago
Zebrafish embryo undergoing gastrulation. Credit to Dr. Gopi Shah at EMBL.
#ZebrafishZunday
🧪
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Maria Bernabeu
7 months ago
Just hot out of the press! Rory developed a 3D microvessel model that recapitulates physiological pericyte coverage. We found that Plasmodium falciparum egress products disrupt the barrier and halt ang-1 secretion. The activator AKB-9778 could rescue barrier disruption! Congratulations, Rory!
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Quanta Magazine
7 months ago
Biophysicists are realizing that there is an undervalued element at play in early development: Aside from genes, mechanical forces also steer the growth of embryos.
@annademming.bsky.social
reports:
www.quantamagazine.org/genes-have-h...
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Genes Have Harnessed Physics to Help Grow Living Things | Quanta Magazine
The same pulling force that causes “tears” in a glass of wine also shapes embryos. It’s another example of how genes exploit mechanical forces for growth and development.
https://www.quantamagazine.org/genes-have-harnessed-physics-to-help-grow-living-things-20251010/
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Alejandro Torres-Sánchez
Markus Deserno
8 months ago
I am super excited to announce that we have a tenure-track faculty position in biophysics open in the Department of Physics at Carnegie Mellon! 🧪 Interfolio link:
apply.interfolio.com/174360
PLEASE, share widely across the blue skies! Let me briefly explain what we're looking for: 1/10
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Jan Rombouts
8 months ago
Please allow me to introduce... our new preprint 🎉 Together with Michael Zhao, Anna Erzberger and Alexander Aulehla, we investigate pattern formation due to aggregation in confined systems. You can find it at
arxiv.org/abs/2509.08533
@michaelzhao.bsky.social
@erzbergerlab.bsky.social
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Maria Bernabeu
8 months ago
Have you ever wondered what happens with your microvessels after exposure to high temperature in fever? In this preprint former postdoc (ans soon to be PI) Viola Introini found that high temperatures cleaves glycocalyx , having severe consequences in malaria
www.biorxiv.org/cgi/content/...
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Febrile temperature enhances Plasmodium falciparum cytoadhesion by disrupting the endothelial glycocalyx
Fever, a universal host defense in infection and inflammation, paradoxically contributes to neurological complications in malaria. While febrile temperatures enhance the expression of parasite virulen...
https://www.biorxiv.org/cgi/content/short/2025.09.07.674757v1
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Mike Dorrity
8 months ago
Very excited to share - the ERC StG is a game-changer for us 🙏 We're going to learn the rules for timing control across cell types in the embryo and we think we can tune them too 🎛️ ⏳📈- reach out if you’d like to be involved !
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Jan Rombouts
9 months ago
The theory was part of my PhD work at KU Leuven with
@lendertgelens.bsky.social
, experimental work by colleagues in Leuven, the Yang lab (U Michigan) and Ferrell lab (Stanford). Find the paper here:
www.nature.com/articles/s41...
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Mechanistic origins of temperature scaling in the early embryonic cell cycle - Nature Communications
Researchers reveal mechanisms underlying non-Arrhenius temperature scaling of early embryonic cell cycle timing, using modeling, cross-species data, and reconstituted oscillations in frog egg extract.
https://www.nature.com/articles/s41467-025-62918-0
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