New research from EMBL scientists is shedding light on how shape transitions help tissue boundaries form during development. The results reveal a new class of adaptive material dynamics & could provide design principles for smart materials that respond to changing environments.

Can pressure gradients persist over long timescales in animal cells? We induced intracellular pressure gradients and examined the resulting flows in single cells. We reveal surprisingly long lasting pressure gradients. More here: elifesciences.org/reviewed-pre...

Fresh from the press💥 We asked what happens when you evolve gene regulatory networks computationally at scale. Do general principles of GRN evolution jump out? Is the process predictable? Read on to find out @prxlife.bsky.social @crick.ac.uk @ucl-ipls.bsky.social 👉 journals.aps.org/prxlife/abst...

📣 New preprint: Mechanochemical feedback, tissue geometry & rigid-body dynamics initiate rotational migration in Drosophila via spontaneous chiral symmetry breaking. A mechanism generalizable to closed epithelia. @sreejithsanthosh.bsky.social biorxiv.org/content/10.1...

We only had a very minor contribution to this story with Alexis, but definitly worth a reading for those interested by patterning, precision and refinment. Nice combining of quantitative live imaging, modeling and optogenetics to dissect vein patterning dynamics www.cell.com/developmenta...

My lab @mpi-muenster.bsky.social is looking for a computational biologist with a passion for imaging and spatial biology. A staff scientist position with long-term perspective! Apply and spread the word 🙏 jobs.mpi-muenster.mpg.de/jobposting/0...

The 19th International CiM-IMPRS Graduate School Meeting is almost here! 🚀Ready to connect minds, spark ideas, and push the boundaries of science together?🔬💡 🔗 Save the date for three days of science, ideas & collaboration. 💭 Can we look forward to seeing you in Münster? #GSM25CiMIMPRS #CiMIMPRS2025

🔬 Speakers: CarenNorden nordenlab.bsky.social and Carl Modes @nicolettapetridou.bsky.social and zenahadjivasiliou.bsky.social Yonit Maroudas-Sacks and Marko Popović Vasudha Srivastava and Asa Kalish www.isscr.org/upcoming-pro... #ISSCR #StemCells #Biophysics #Mechanobiology #ScienceSpotlight

Everything (and more) you wanted to know about Nodal Signaling. A Paradigm for TGFβ Signaling in Embryonic Development | Annual Reviews - www.annualreviews.org/content/jour...

Thrilled to bits to see our latest work online in Dev Cell! 🥳 We wanted to know how cells build functional organs with precision🫀🫁📏 Here we show how coupling of cell shape and organ function fine tunes the form and contractile power of the developing #zebrafish heart 1/n tinyurl.com/cell-stretch

Our study on endothelial mechanics made the news! 🤩 Super nice and clear article on our findings and their implications. www.snexplores.org/article/how-...

Hi I’m @yamini-ravichan.bsky.social , a postdoc interested in the mechanical induction of topological defect-mediated morphogenesis. I use different organisms to study the role of topological defects shaping development & regeneration. Below is an insight to the field!

Pls spread the word! We have a postdoc position available in the Rocha Lab @mpi-muenster.bsky.social. Join our team to study mechanisms underlying robust organ development using zebrafish embryos and human organoids. mpi-muenster.mpg.de/career

June in preprints 📃 We've trawled through the latest #preprints in #DevBio, #StemCells and related fields, and here's a list of what we found: thenode.biologists.com/june-in-prep... Congrats to everyone involved! As usual, if we've missed anything, let us know.

It’s #FluorescenceFriday again! @maikbischoff.bsky.social encouraged me to post more beautiful images, so I hope you enjoy this image of Ajuba at Tricellular Junctions in #Drosophila 🪰 want to know more? Click here: doi.org/10.1016/j.cu...

Kristian Blom, Uwe Thiele, Alja\v{z} Godec: Dynamic Models for Two Nonreciprocally Coupled Fields: A Microscopic Derivation for Zero, One, and Two Conservation Laws https://arxiv.org/abs/2507.01105 https://arxiv.org/pdf/2507.01105 https://arxiv.org/html/2507.01105

What happens when physics meets biology? Dive into active matter, the driving force behind cytoskeletal organization, tissue morphogenesis & more. July 11 @ 9 a.m. ET. http://dlvr.it/TLZGBf

🚨Next week, Wed 09/07 | 16:00 UK - Online Seminar🚨 "Feedback between morphogen signalling and tissue architecture drives robust developmental patterning" by Dr Zena Hadjivasiliou. To attend online please register to our 📧 for the zoom link: lists.cam.ac.uk/sympa/subscr...

New preprint out! We show how cellular nematic order can be harnessed to program tissue-wide force fields and guide 3D shape transformations. The tissue morphogenesis logic, now engineered into living, programmable materials. www.biorxiv.org/content/10.1... #ActiveMatter #TissueEngineering

FINALLY out in #Science Advances! 🎉 3 years of hard work, a fantastic team — and I’m proud to be first and co-corresponding author! It's about Plexin signaling driving collective cell migration & organ sculpting. Check out the videos 😀 www.science.org/doi/10.1126/... #DevBio #CellBio #Microscopy

Exciting @sfb1348.bsky.social with Alberto Elosegui-Artola (Francis Crick Institute London). He will speak about "The ECM viscoelasticity controls tissue spatiotemporal dynamics". More information: www.uni-muenster.de/SFB1348/en/i... Everyone is welcome!

Do tissue material properties impact morphogen transport? Yes! And morphogens know it. Thanks to @nicolettapetridou.bsky.social who got us involved and to Bernat Corominas-Murtra, and kudos to @cami-autorino.bsky.social @dianakhorom.bsky.social and all the authors! 🧵 below if you are curious 👇

Very happy to see our latest collab out on bioarxiv - check out this thread by @cami-autorino.bsky.social

In preprints: an evo-devo approach integrates multicellular shape diversity and active surface mechanics Karina Pombo-Garcia and Alexander Mietke discuss a recent #preprint from the groups of Guillaume Salbreux and ‪@aikmi.bsky.social‬ journals.biologists.com/dev/article/...

The evolution of shape diversity through the lens of physics—explored in our new paper! A fruitful collaboration between our lab @EMBL, Salbreux’s lab @unige & others, led by @BailleulRichar1—now independent at @ENS_ULM—& Nicolas Cuny. bit.ly/3WRqdEa