Are you looking for a PhD in Biological Physics / Math Biology? We are recruiting at UCL, link to apply now active: www.findaphd.com/phds/project... Project very flexible, drop me a line if you are interested and want to find out more.

Researchers have identified a signalling feedback loop that may have been vital to the evolution of insect wings and therefore flight. The signals, called morphogens, act like lighthouses in most developing tissues, guiding nearby cells towards their fate. www.crick.ac.uk/news/2025-11...

An Asgard archaeon with internal membrane compartments Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors! www.biorxiv.org/content/10.1...

Looking forward to this meeting!! Join us this February in Heidelberg 🦋🪰🐟🐁🌱🧫🦠

🔊 We are looking for a PhD student to join our group and the vibrant community @ucl.ac.uk @ucl-ipls.bsky.social and @crick.ac.uk 💥. Details on the call: www.jobs.ac.uk/job/DPF708/5... and our project on offer: ucl-epsrc-dtp.github.io/2026-27-proj.... Please share and drop me a line if interested!

Couldn’t be prouder of the first PhD graduate of the lab, super congrats @danafd.bsky.social 🙌🎓🌟. Such a pleasure to supervise you together with @cohouart.bsky.social @houartlab.bsky.social, the learning journey never ends 😌. Huge thanks to @jamesasharpe.bsky.social and Sylvie Retaux for examining 💥

Opportunity for a Master’s/Bachelor’s student: - Join us for up to 5 months 🗓️ - Build computational/mathematical models 💻 - Learn about genotype-phenotype maps and evolution 🧬 - Work closely with PhD student Manuela Giraud - full info here: www.crg.eu/en/content/t...

We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions. Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research. Apply now ➡️ www.crick.ac.uk/careers-stud...

Don’t miss the exciting ISSCR Webinar: Integrating Biophysics into Stem Cell Biology next Tuesday October 14! The webinar features paired tandem talks that brings together experimentalists and theorists working at the interface of stem cell biology and biophysics. 1/2 www.isscr.org/upcoming-pro...

Latest from ours: www.cell.com/cell-reports... This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵

Motivated graduates with backgrounds in biological or biomedical sciences, physics, chemistry, mathematics, engineering and/or computer science are invited to apply to our 4-year fully funded PhD programme. Apply by 05 November 2025 www.crick.ac.uk/careers-and-...

We have a PhD project here, along with many other cool projects: "Characterising and predicting seizure onsets from longitudinal sEEG data", www.crick.ac.uk/careers-and-... with @flor-iacaruso.bsky.social (Crick), Torsten Baldeweg (UCL) and Martin Tisdall (UCL). Apply by: 14 November 2025.

LMB PhD studentship available in the Baum lab to use informatics to infer cell structure from genomic data in collaboration with the brilliant Tom Williams. If you write to me and I don’t reply - try again - the spam filter is hungry…

New research from EMBL scientists is shedding light on how shape transitions help tissue boundaries form during development. The results reveal a new class of adaptive material dynamics & could provide design principles for smart materials that respond to changing environments.

Come join us in Basel! @biozentrum.unibas.ch is an amazing place to start your group.

Can pressure gradients persist over long timescales in animal cells? We induced intracellular pressure gradients and examined the resulting flows in single cells. We reveal surprisingly long lasting pressure gradients. More here: elifesciences.org/reviewed-pre...

Our latest preprint! Into morphogenesis, Yap, ECM, signaling, vertex models, feedbacks/robustness? There is something here for everyone. We discovered a positive feedback loop that extends inner ear canals, and a built-in mechanism that shuts it down when morphogenesis is done. tinyurl.com/464wsjhd

🚨New Preprint🚨 How do morphogens integrate dynamically with other modes of signalling+what can this do for pattern precision and robustness? We used the Drosophila visual system as our muse to dive into this question with the amazing Vil Fernandes @ucl.ac.uk 🧠🪰 👇 www.biorxiv.org/content/10.1...

Development does not happen in isolation! Material properties, geometry, stiffness, fluid flows...can all steer how development unfolds. If you’re exploring these kinds of questions, we’d love to see your work @dev-journal.bsky.social More info below ⬇️

I love the Ig Nobel prizes, asking questions for the sake of curiosity is so inherent to being human and the reason I love doing science. Make some notes for your pasta protocols y'all!

We only had a very minor contribution to this story with Alexis, but definitly worth a reading for those interested by patterning, precision and refinment. Nice combining of quantitative live imaging, modeling and optogenetics to dissect vein patterning dynamics www.cell.com/developmenta...

Please allow me to introduce... our new preprint 🎉 Together with Michael Zhao, Anna Erzberger and Alexander Aulehla, we investigate pattern formation due to aggregation in confined systems. You can find it at arxiv.org/abs/2509.08533 @michaelzhao.bsky.social @erzbergerlab.bsky.social

We have been fortunate to have a stream of extraordinary Fellows as part of our community. They have gone on to wonderful positions .. It is time, once more, to renew. Our annual search is a chance for us to understand what the brightest young people in the community are doing! Please apply!

Crick researchers have generated a computer simulation of the evolution of gene networks, which has helped them establish general principles about the evolution of body patterns over time. www.crick.ac.uk/news/2025-09...

Fresh from the press💥 We asked what happens when you evolve gene regulatory networks computationally at scale. Do general principles of GRN evolution jump out? Is the process predictable? Read on to find out @prxlife.bsky.social @crick.ac.uk @ucl-ipls.bsky.social 👉 journals.aps.org/prxlife/abst...

(1/14) I’m happy and proud to introduce: SpinePy – a framework to detect the "spine" of gastruloids and measure biological and physical signals in a local dynamic 3D coordinate system. www.biorxiv.org/content/10.1...

Side hustle level-up! My book, IN THE BEGINNING, will be published by @harperonebooks.bsky.social in 2027! It's about the human embryo, how it gets built, and what it means for where we come from and where we're going. @harpercollins.bsky.social (1/2) @socdevbio.bsky.social #devbiol #scicomm

My lab @mpi-muenster.bsky.social is looking for a computational biologist with a passion for imaging and spatial biology. A staff scientist position with long-term perspective! Apply and spread the word 🙏 jobs.mpi-muenster.mpg.de/jobposting/0...

Thrilled to share the first story from my postdoc! 🎉 A wonderful experiment + simulations collaboration. In the Drosophila wing, we find that 3D cell shapes affect signalling range and fine-tune developmental patterning www.biorxiv.org/content/10.1... Thread below ⬇️

Out now! Our very first [email protected], an impressive feat by @tobyandrews.bsky.social where we show how a developing heart grows and scales up its morphological complexity to keep beating...an excellent summary below ⬇️ www.cell.com/developmenta...

A Summer reading recommendation: new primer in @dev-journal.bsky.social explains how dynamical systems theory unlocks the logic of developmental patterning Everything from bistable switches & oscillators to phase portraits & more with Python code to explore journals.biologists.com/dev/article/...

If you want to discover Vienna, Austria in general (and @istaresearch.bsky.social groups in particular) now have 4-year fellowships for postdocs coming from a US institution (up to 500,000 EUR)! Contact me if interested!

🚨Job alert in theory/math devbio 🚨 I’m currently advertising postdoc positions to join my group. We’re building reaction-diffusion models to understand some of the crazy things embryos can do. We are based in a beautiful part of Scotland :). Please share! www.abdnjobs.co.uk/vacancy/rese...

Patterning in dynamical tissues, great review by @dianapinheiro.bsky.social and Tony Tsai www.sciencedirect.com/science/arti...

Congratulations to Dr. @akanksha-jain.bsky.social, Gilles Gut, and the Treutlein Lab and @graycamplab.bsky.social on their work live imaging brain #organoid growth! @nature.com article: go.nature.com/4la2yZh Episode with discussion: bit.ly/4nzLrCp

📣 New review! Dynamical systems and low-dimensional geometric structures in phase space help rationalize how embryos develop form and function, from large datasets. We focus on morphogenesis, cell differentiation, and their interconnection. @alex-plum.bsky.social sciencedirect.com/science/arti...

🚨 Join us tomorrow for this really exciting talk on the interplay between morphogen signalling and tissue organization! 🚨

Useful perspective incorporating GRNs & gene modules into theory of evolutionary novelty Parker & Pennell emphasise gene modules, not individual genes, as fundamental units of phenotypic evolution Provides a needed evolutionary lens for analysing scRNAseq & cell types www.cell.com/current-biol...

🔊 We are recruiting a postdoc to join us @crick.ac.uk and @ucl.ac.uk @ucl-ipls.bsky.social. Repost and help us spread the word and reach out if interested and have questions. Details and how to apply: www.ucl.ac.uk/work-at-ucl/...

New preprint out! We show how cellular nematic order can be harnessed to program tissue-wide force fields and guide 3D shape transformations. The tissue morphogenesis logic, now engineered into living, programmable materials. www.biorxiv.org/content/10.1... #ActiveMatter #TissueEngineering

How to turn a layer of fibroblasts into a tulip 🌷? Check out our new pre-print on shape-programmable living surfaces. Led by @pauguillamat.bsky.social‬ www.biorxiv.org/content/10.1...

Delighted to share our latest work on the mechanisms of epithelial curvature and 3D morphogenesis ! Amazing work from newly graduated Dr @courtneyl7a7.bsky.social 🎉 @lmcb-ucl.bsky.social @uclnews.bsky.social @ucllifesciences.bsky.social www.sciencedirect.com/science/arti...

Here our latest work on how morphogens trigger tissue phase transitions to tune their own length-scales and time-scales - An exciting collaboration with @zhvas.bsky.social @dianakhorom.bsky.social Bernat Corominas-Murtra and heroic experiments by the incredible @cami-autorino.bsky.social @embl.org

Do tissue material properties impact morphogen transport? Yes! And morphogens know it. Thanks to @nicolettapetridou.bsky.social who got us involved and to Bernat Corominas-Murtra, and kudos to @cami-autorino.bsky.social @dianakhorom.bsky.social and all the authors! 🧵 below if you are curious 👇

Very important @nicolettapetridou.bsky.social‬ report #mechanochemical signalling control fate transitions www.biorxiv.org/content/10.1... w/ wide/significant implications. Perhaps the clearest indication so far of HOW #NotInTheGenes cell interactions mechanical pattern gene expression #MustRead

Our latest "Dynamic Landscape Analysis of Cell Fate Decisions: Predictive Models of Neural Development From Single-Cell Data" A rigorous mathematical foundation for Waddington's landscape to study cell fate decision making Applied to ventral neural tube development www.biorxiv.org/content/10.1...

We are excited to share our preprint describing how Sulfolobus cells coordinate DNA segregation with cell division! In eukaryotes this type of regulation involves checkpoints and CDK-cyclins. But how does this work in archaea? This is the question we ask in our paper: www.biorxiv.org/content/10.1...

And one more from @callumbucklow.bsky.social on how verterbal regionalisation and counts are linked in evolution. See his tutorial below. Well done Callum!

New paper out in @pnas.org We followed cells migrating along signalling gradients in 3D, and found they collectively behave as a living droplet - a self-propelling fluid that grows. www.pnas.org/doi/10.1073/...

📢Registration is open for our IPLS Annual Symposium, 11th June 2025! We will showcase exciting #interdisciplinary #research performed by IPLS researchers and collaborators. Limited spaces, register early to avoid disappointment 👇 ucl.ac.uk/physics-livi...