Here at CRI #relentlessdiscovery = #NeverChaseReality and McBrayer Lab is ready to cheer the #USMNT  to the next round. Gooooooooal ⚽️🏆#StarsAndStripes #FIFAWorldCup #FWC26 #WeAre26

One more Dr. on his way to Dr. Dr. ✔️ Congrats, Mark, on a successful defense! Dr. Mannino is headed back to medical school to finish his M.D. One more @seanjmorrison.bsky.social grad student off to continue #relentlessdiscovery

ONLINE NOW in @natcellbio.nature.com: ecDNA anchors to H3K27ac-marked active regions on chromosomes to survive normal mitotic cell division and persist into the next generation of daughter cells. Read more about the latest #relentlessdiscovery from CRI's Wu Lab ⬇️ @yipengxie.bsky.social

We made the cover 🤩 !! Check out this incredible painting by @kahsage.bsky.social !!

👏👏 On a roll with #MotivationMonday & another successful dissertation defense! Congrats to @haozhulab.bsky.social & @rjdlab.bsky.social lab grad student Roger Liang. Dr. Liang is headed back to medical school to finish up his M.D. Onward! #relentlessdiscovery 🧪

ONLINE now in @natcellbio.nature.com: Our newest PI @henrydebelly.bsky.social has published his postdoctoral work about Rac & Rho. Check out his 🧵⬇️ #relentlessdiscovery 🧪

#MotivationMonday another successful Ph.D. defense! Congrats to McBrayer Lab grad student Charley Edgar, (second from right). Dr. Edgar is headed back to medical school to finish up his M.D. Onward! #relentlessdiscovery 🧪

Coverage of @peterlylab.bsky.social's #relentlessdiscovery 🧪 originally published in @cellpress.bsky.social ⬇️

🚨Seeking 2 #postdocs ⬇️ join the #relentlessdiscovery 🧪 #ScienceJobs #SciJobs #JobRxiv #STEMJobs #AcademicTwitter #PhDJobs

Proud milestone for our lab – Congrats to our first two graduate students, Lizz Maurais, PhD, and Justin Engel, PhD (@justeng95.bsky.social)! We also celebrated Lizz’s last day as she moves on to an exciting new adventure. Good luck Lizz!

Had a fun conversation with @sciencenews.bsky.social about our recent findings. Thanks for covering our work!

Like prisoners tunneling out of jail, damaged DNA travels via tubelike structures between neighboring cells. https://www.sciencenews.org/article/damaged-dna-spread-nanotubes-cells-cancer

#relentlessdiscovery from @peterlylab.bsky.social 🧪

🧵👇 for @peterlylab.bsky.social's deep-dive into the deets of his latest #relentlessdiscovery 🧪 worth a 🔖

ONLINE NOW in @cellcellpress.bsky.social: @peterlylab.bsky.social has discovered large pieces of DNA can transfer directly between human cells & that DNA can persist, change how the recipient cell functions. 🧪 Read more about this #relentlessdiscovery ⬇️ cri.utsw.edu

#thesisThursday: Been a week since Greg Mannino from @haozhulab.bsky.social successfully defended! Congrats, Dr. Mannino 😎 and best of luck continuing the #relentlessdiscovery as a postdoc at @washu.edu.

We already thought @haozhulab.bsky.social hung the (liver-shaped) moon🌙 & now his #relentlessdiscovery is promulgated. Check out Chp 6, "When Our Bodies Autocorrect," p140 to read how somatic mutations could give us "hope." Great topic, @roxannekhamsi.bsky.social! 🧪 Watch out #booktok 🤓

Congrats, @walterwchen.bsky.social! 🎉 The next CRI postdoc off to pursue more #relentlessdiscovery 🧪

More highlights from @natmetabolism.nature.com about the importance of newly developed nitrogen mapping 🧪 www.nature.com/articles/s42... #relentlessdiscovery @milansavani.com

1/12 🛣️ Mapping nitrogen metabolism has lagged carbon due to substrate diversity. In @natmetabolism.nature.com, we introduce a platform to do this mapping at scale and identify mechanisms by which differentiation state dictates pyrimidine synthesis. 🧵👇 🔗 www.nature.com/articles/s42...

ONLINE NOW in @natmetabolism.nature.com: McBrayer Lab & first-author @milansavani.com have discovered cell maturity determines pyrimidine synthesis pathway preference using their new nitrogen metabolism profiling platform, organoid model. More ⬇️ cri.utsw.edu/cell-maturit... #relentlessdiscovery 🧪

I am so grateful for this honor - grateful to my mentors, lab, and family. Thank you @seanjmorrison.bsky.social for your support. And how great to be elected with some very good friends and two awesome UTSW colleagues, Elizabeth Chen and Joel Elmquist. Feeling very fortunate today.

Big congrats to my postdoc mentor @rjdlab.bsky.social on his election to NAS!! 🎉🎉🎉 An inspiring physician-scientist and wonderful person and mentor.

🌟From the desk of @seanjmorrison.bsky.social: It's a great day for CRI, which now has 2 @nasonline.org members. Congratulations to @rjdlab.bsky.social and his laboratory on this recognition for the quality and impact of their work! #relentlessdiscovery 🧪 cri.utsw.edu/deberardinis...

Pleased to share our review on chromosomal instability (CIN) and aneuploidy in cancer, led by Amanda Mennie. Now out @annualreviews.bsky.social! www.annualreviews.org/content/jour...

New paper from Dr. Wen Gu on the impact of L-2-hydroxyglutarate deficiency on neural stem cell function and neuronal differentiation. Interesting connection between an IEM and chronic oncogene activation. Thanks to Dr. Bushra Afroze and her patients for participating. www.jci.org/articles/vie...

I think the bucket was good luck. Go Blue!!!

Had a #GoBlue moment last week when Omer Yilmaz, Ph.D., came to speak about his #relentlessdiscovery for the CRI Speaker Series. Omer's ice bucket from @seanjmorrison.bsky.social Lab made the move from Ann Arbor to Dallas and is still being used two decades later! 🧪

Unfurl @casanovalab.bsky.social's whole 🧵👇 ... we're pumped to be adding another scientist passionate about #relentlessdiscovery to our roster. Onward! 🧪

Learn more about CRI's newest investigator @henrydebelly.bsky.social and his #relentlessdiscovery to define the molecular controls of membrane fluidity in order to influence immune and #cancer cell function. 👇 cri.utsw.edu/meet-dr-henr... 🧪

ONLINE now in @cellpress.bsky.social: A review by CRI's @haozhulab.bsky.social about their #relentlessdiscovery and how somatic mutations are becoming a key discovery engine for disease genetics. 🧪 Read more ⬇️ www.cell.com/cell/fulltex...

#RareDiseaseDay2026 #relentlessdiscovery 🧪

Great time in Boston, as always! Thanks for the invitation!

Become a CRI #postdoc & be part of CRI's #relentlessdiscovery 🧪 Apply at cri.utsw.edu/careers #jobs #opentowork #jobopenings #sciencejobs #HiringNow

My lab @cri-utsw.bsky.social is looking for a highly motivated postdoct interested in mechanobiology! We are building a highly collaborative and interdisciplinary team working on how mechanical forces shape immune and cancer cell behavior. Come do cool science with me! lnkd.in/gKEXWUGy

🚨NEW PI ALERT🚨 @henrydebelly.bsky.social is in the house, and look at that *fresh* new office. Clean slate for his next #relentlessdiscovery in CRI's Tissue Regeneration Program (TRP). Onward! Read more about his new lab 👉 cri.utsw.edu/faculty/henr... 🧪 @haozhulab.bsky.social

ICYMI, there's a new project CRI's @haozhulab.bsky.social will collaborate on: trying to create artificial livers. Read more ⬇️ #relentlessdiscovery #CRIcollaboration 🧪 www.utsouthwestern.edu/newsroom/art...

We can't wait to see you next week, @henrydebelly.bsky.social! #relentlessdiscovery

Today 1/9 at 4pm: UCSF Cancer Center Friday Seminar Series | Sean Morrison, PhD @seanjmorrison.bsky.social Founding Director, @cri-utsw.bsky.social presents "Immune regulation of melanoma metastasis" cancer.ucsf.edu/seminars Hosted by @rushika-perera.bsky.social @ucsanfrancisco.bsky.social

Millions of years ago, our ancestors lost the ability to make vitamin C. It’s long been unclear why. But Dallas researchers may have uncovered an explanation — and it involves parasitic infections.

Featured in @dallasnews.com: CRI's Agathocleous Lab talks about their recent #relentlessdiscovery: a potential benefit to vitamin c deficiency. 🧪 Read more ⬇️ www.dallasnews.com/news/2026/01...

That’s a wrap on the past 12 months, with even more #relentlessdiscovery to come in 2026. cri.utsw.edu/discoveries/ @seanjmorrison.bsky.social @rjdlab.bsky.social @haozhulab.bsky.social 🧪 #stemcells #regeneration #CancerResearch #metabolism #NYE2025 #NYE2026

ONLINE NOW in @pnas.org: Agathocleous Lab, collaborators discover why humans, some animals may need intermittent vitamin C deficiency: to survive parasite infections. 🧪 Read more ⬇️ cri.utsw.edu/loss-of-vita... #relentlessdiscovery

Just a nice lab happy hour before the holidays

Exciting news from the @rjdlab.bsky.social (with co-first author @zhengwu1.bsky.social)! We've uncovered a crucial new mechanism that controls the supply of purine nucleotides—a pathway essential for cancer growth.

Super excited to share that my second project in the @rjdlab.bsky.social is now published in Science! Many thanks to all co-authors, especially @ptnguyen.bsky.social for his expertise in structural biology and enzymology! And big thanks to Ralph for his incredible mentorship and support!

ONLINE NOW in @science.org: @haozhulab.bsky.social discovers location matters for liver cancer's origins. 🧪 Read more ⬇️ cri.utsw.edu/zhu-lab-show... 🔖 @haozhulab.bsky.social's breakdown ➡️ x.com/Zhu_Lab/stat... #relentlessdiscovery

ONLINE NOW in @science.org: DeBerardinis Lab discovers protein regulating balance between purine nucleotide production pathways. 🧪 Read more ➡️ cri.utsw.edu/deberardinis... 🔖 full breakdown ⬇️

6 years ago, Lizz took a leap of faith by moving across the country to join our new and empty lab as a research tech. She then became our 1st grad student, playing a major role in shaping our research directions and lab culture. Today she defended her PhD, and I couldn’t be more proud.

Defended! 🍾 Introducing Elizabeth Maurais, Ph.D. 🎉 Congrats on your successful #dissertationdefense. Dr. Maurais was joined by her mentor @peterlylab.bsky.social & other Ly Lab mates. Next stop: #postdoc! 🧪