Super excited to share that my second project in the @rjdlab.bsky.social is now published in Science! Many thanks to all co-authors, especially @ptnguyen.bsky.social for his expertise in structural biology and enzymology! And big thanks to Ralph for his incredible mentorship and support!

ONLINE NOW in @science.org: @haozhulab.bsky.social discovers location matters for liver cancer's origins. 🧪 Read more ⬇️ cri.utsw.edu/zhu-lab-show... 🔖 @haozhulab.bsky.social's breakdown ➡️ x.com/Zhu_Lab/stat... #relentlessdiscovery

ONLINE NOW in @science.org: DeBerardinis Lab discovers protein regulating balance between purine nucleotide production pathways. 🧪 Read more ➡️ cri.utsw.edu/deberardinis... 🔖 full breakdown ⬇️

6 years ago, Lizz took a leap of faith by moving across the country to join our new and empty lab as a research tech. She then became our 1st grad student, playing a major role in shaping our research directions and lab culture. Today she defended her PhD, and I couldn’t be more proud.

Defended! 🍾 Introducing Elizabeth Maurais, Ph.D. 🎉 Congrats on your successful #dissertationdefense. Dr. Maurais was joined by her mentor @peterlylab.bsky.social & other Ly Lab mates. Next stop: #postdoc! 🧪

We moved the RJDLab potluck to Halloween this year. Thanks to Gaby Cano for organizing! (And decorating).

Happy Halloween 🎃 Scary: food in the lab (👋 Harrison) Sweet: problem-solving lab managers, like Jessica! 🎃🍬🤍🦇🕷️🕸️🐈‍⬛💀🧡🐦‍⬛🕯️🖤‍🍂🍁🪾🔮🧪 @rjdlab.bsky.social

ONLINE NOW: CRI's Ohlstein Lab presents new research that reevaluates whether histones are asymmetrically segregated during asymmetric divisions of stem cells in Drosophila, in @pnas.org. Read more ⬇️ www.pnas.org/doi/10.1073/... #relentlessdiscovery 🧪

📍 #MotivationMonday: "Resilience isn’t something that you are born with – it is a set of skills you have to cultivate.” [email protected] Read more about pushing through adversity & #relentlessdiscovery with Sean & @rjdlab.bsky.social ⬇️ www.utsouthwestern.edu/ctplus/stori...

Interested in organellar metabolomics? Check out my talk tomorrow on how the Rapid Organellar IP technology has enabled discoveries in organellar biology over the past 10 years! Ty Tech Networks for the invite! @cri-utsw.bsky.social @rjdlab.bsky.social www.technologynetworks.com/proteomics/o...

Many thanks also to @cri-utsw.bsky.social for providing such an excellent environment for training and discovery.

Congrats to all Damon Runyon's SPARK Scholars, including our own scholar Imani Williams who is studying cancer metabolism. Thank you Damon Runyon Cancer Research Foundation @damonrunyon.org for supporting this great initiative. www.damonrunyon.org/news/entries...

Thrilled to announce the launch of my lab @cri-utsw.bsky.social at UTSW this January! We will explore how cells sense and respond to mechanical forces, focusing on membrane mechanics to reveal how tension and signaling work together to shape cell behavior.

We're growing! Our newest Investigator @henrydebelly.bsky.social will join the CRI Tissue #Regeneration Program in January 2026. Learn more about Henry ➡️ cri.utsw.edu/faculty/henr... and 📌apply to research in his lab cri.utsw.edu/careers

One week left to apply!

Excited to present my research at the upcoming University of Utah Rising Stars Symposium and meet fellow scientists who love metabolism! @cri-utsw.bsky.social @rjdlab.bsky.social

Thank you @cri-utsw.bsky.social postdocs!

We have the best postdocs! We appreciate you being a critical part of our CRI team to help discover the treatments of tomorrow. #npaw2025 #npaw #relentlessdiscovery 🧪

🎉 JUST ANNOUNCED: @haozhulab.bsky.social named project co-leader for UTSW liver cancer SPORE. His project will study how to prevent hepatocellular carcinoma — which accounts for >85% of liver cancer cases across the nation. Read more ⬇️ cri.utsw.edu/zhu-named-co... #relentlessdiscovery 🧪

🔬 APPLY NOW: Seeking faculty scientists in #stemcells #TissueRegeneration #metabolism & #cancerbiology. You ready for #relentlessdiscovery at our collaborative Institute? Learn more at cri.utsw.edu/careers & apply before Oct. 15. 🤜💥🤛 #jobs #faculty #facultyjobs #ScienceJobs 🧪

Excited to join the @cri-utsw.bsky.social community to advance discoveries in genome instability. We are grateful to UTSW Pathology for 6 wonderful years. 🚨 We are also recruiting motivated postdocs to study how mitotic errors and aberrant nuclear structures drive cancer genome evolution—join us!

WELCOME to the Institute, @peterlylab.bsky.social! Dr. Ly studies how cells maintain genomic integrity and how dysregulation of these processes impacts human health. 🧪Learn more about his research 👉 cri.utsw.edu/faculty/pete... #relentlessdiscovery

👉New article in @newscientist.com features a #relentlessdiscovery 🧪 from CRI's Agathocleous Lab ⬇️

Thrilled and deeply honored to be named a 2025 Pew Biomedical Scholar! Huge congrats to my friend and colleague @cri-utsw.bsky.social Javi, who’s also joining the Pew family as a Pew-Stewart Scholar. CRI is on fire—let’s go make some bold, groundbreaking science happen! 🔥🧪✨

🎉 Huge congrats to Drs. Javier García-Bermudez and @hrshin.bsky.social for being named Pew-Stewart & Pew Scholars! Well-deserved recognition for two outstanding @cri-utsw.bsky.social scientists!

Congrats! 👏👏👏 Two CRI scientists named 2025 Pew-Stewart & Pew Scholars — Javier Garcia-Bermudez, Ph.D. & @hrshin.bsky.social — to advance cancer, biomedical research 🧪 Read more about their #relentlessdiscovery ⬇️ cri.utsw.edu/two-children... @pewtrusts.org

ONLINE NOW in @biologists.bsky.social "Disease Models & Mechanisms:" from CRI's @haozhulab.bsky.social about siRNAs for liver cancer prevention ⬇️ read more #relentlessdiscovery 🧪 journals.biologists.com/dmm/article/...

Big thanks to Jianguo Wu, Min Zhuang, @natcellbio.nature.com for a great News and Views on our work and that of Michael Skowyra, Tom Rapoport. www.nature.com/articles/s41...

1/New paper on peroxisome assembly, reporting the detailed mechanism of PEX39, a new peroxin involved in PTS2 protein transport. Fantastic work by ‪@walterwchen.bsky.social‬ and a dream team of collaborators, as explained below. www.nature.com/articles/s41...

🧵⬇️ @walterwchen.bsky.social #relentlessdiscovery 🧪

ONLINE NOW in @natcellbio.nature.com: CRI's @rjdlab.bsky.social Lab postdoc @walterwchen.bsky.social & international colleagues have discovered the first new human peroxin in 20 years. Read more ⬇️ cri.utsw.edu/deberardinis... #relentlessdiscovery 🧪

ONLINE NOW in @nature.com: latest research from CRI's @rjdlab.bsky.social Lab, full 🧵⬇️ #relentlessdiscovery 🧪

👏👏👏 Congrats to CRI grad student researcher Dylan Calhoon! He'll be presenting about the most recent #relentlessdiscovery from the Garcia-Bermudez Lab. 🧪

ONLINE NOW: 2 new somatic mutation studies🧪 in #liver disease from CRI's @haozhulab.bsky.social 🟠 @jhepatology.bsky.social w/ postdoc Qiyu Zeng, Ph.D. www.journal-of-hepatology.eu/article/S016... 🟠 @jclinical-invest.bsky.social w/ grad student Greg Mannino www.jci.org/articles/vie... ⬇️Hao's thread🧵

Excited to receive an NIH K08 Clinical Investigator Award to support my research on #mitochondria #peroxisomes 😀 The $775K will be critical in helping me transition to independence as I begin looking for a place to start my lab 🙏🏻 @the-asci.bsky.social

Thanks Nature Cancer for the chance to reflect on some factors that led me to study cancer metabolism. For the trainees and other young scientists: the critical events that shape your career might not be obvious while they are happening. Keep an open mind and trust your instincts. rdcu.be/evi4I

Research News in @theaacr.bsky.social's "Cancer Discovery" features CRI Garcia-Bermudez Lab's #relentlessdiscovery "Lipoprotein Uptake through Glycosaminoglycans Blocks Ferroptosis in Cancer" 🧪 Read more ➡️ aacrjournals.org/cdnews/news/...

We’re truly fortunate to have such extraordinary scientists engaging with our summer students. Thank you, @rjdlab.bsky.social, for sharing the groundbreaking science you are leading at @cri-utsw.bsky.social. I’m confident that your presentation inspired our students and sparked their curiosity.

Today in @dallasnews.com by @sodendritic.bsky.social: "Dallas researchers find cancer’s secret weapon to defeat death" ⬇️ read more www.dallasnews.com/news/2025/06... 🧪 #relentlessdiscovery @rjdlab.bsky.social

Nature research paper: Glycosaminoglycan-driven lipoprotein uptake protects tumours from ferroptosis https://go.nature.com/4e1Wek9

Excellent news for a fantastic young scientist and colleague. Congrats @walterwchen.bsky.social !

Honored to receive @bwfund.bsky.social Career Award for my research on #mitochondria #peroxisomes and be 1st neonatologist awardee! The $700K for starting my lab will enable exciting research on #organelles #metabolism to help medicine’s smallest patients. #neonatal www.bwfund.org/news/bwf-ann...

Momentous day for CRI @rjdlab.bsky.social postdoc & UTSW Neonatologist @walterwchen.bsky.social 🎉 recipient of a 2025 @bwfund.bsky.social Career Award for Medical Scientists! 👏👏 He will continue his #relentlessdiscovery studying uncharacterized organellar proteins 🧪 ⬇️ cri.utsw.edu/deberardinis...

GAGs regulate LDL uptake and protect cells from lipid oxidation - new from Javier Garcia-Bermudez.

ONLINE NOW in @natureportfolio.nature.com 🧪 CRI's Garcia-Bermudez Lab has discovered tumors can tap a nontraditional pathway [sulfated glycosaminoglycans (GAGs)] to acquire lipoproteins & enrich cancer cells with an antioxidant shield to survive stress. Read more ⬇️ #relentlessdiscovery

Today's #thursdaymotivation is courtesy CRI's @haozhulab.bsky.social: Congrats Gianna Maggiore for your successful #dissertationdefense! Dr. Maggiore's family and lab mates joined to celebrate. Next steps: summertime fun & finishing her M.D. 🎉 #relentlessdiscovery

Great day for CRI's @hrshin.bsky.social, who received $250K from the Cancer Prevention and Research Institute of Texas to fund her #relentlessdiscovery🧪 "mapping and disabling unique lipid signaling and metabolic pathways that fuel glioblastoma." Read more ⬇️ cprit.texas.gov/news-events/...

ICYMI in @natcellbio.nature.com 📖 CRI's Gerta Hoxhaj, Ph.D., @dohunkim.bsky.social & colleagues have discovered how mitochondria use NADPH to fuel fatty acid synthesis, lipoylation. Read more about the biochemical method they developed ➡️ cri.utsw.edu/hoxhaj-lab-d... #relentlessdiscovery 🧪

Thanks Shuyuan Zhang and Biochemistry PhD students for inviting me to Case Western Reserve University for the Harlan G Wood lecture. It was an honor and pleasure. See you all soon!

ONLINE NOW in @naturecellbiology.bsky.social: Latest #relentlessdiscovery from CRI's Hoxhaj Lab is mitochondrial NADPH fuels mitochondrial fatty acid synthesis and lipoylation to power oxidative metabolism. 🧪 Study ➡️ nature.com/articles/s41... 🧵 on X x.com/Gerta_Hoxhaj...