A true legend. www.bcm.edu/about-us/lea...

new out in Nature, targeting FSP1 to trigger ferroptosis www.nature.com/articles/s41... www.nature.com/articles/s41...

ONLINE NOW in @science.org: DeBerardinis Lab discovers protein regulating balance between purine nucleotide production pathways. 🧪 Read more ➡️ cri.utsw.edu/deberardinis... 🔖 full breakdown ⬇️

ONLINE NOW in @science.org: @haozhulab.bsky.social discovers location matters for liver cancer's origins. 🧪 Read more ⬇️ cri.utsw.edu/zhu-lab-show... 🔖 @haozhulab.bsky.social's breakdown ➡️ x.com/Zhu_Lab/stat... #relentlessdiscovery

In this Editor's Choice, Maggiore, Zhu @haozhulab.bsky.social and colleagues reveal the high clinical potential of GalNAc-siRNA-based strategies for preventing hepatocellular carcinoma development in high-risk individuals, particularly through targeting ANLN. doi.org/10.1242/dmm.... #HCC #cancer

Introducing 2 new papers from my lab on somatic mutations in liver disease. The 1st is about a mutated gene that leads to improved clone fitness and organismal health (CIDEB). The 2nd is about a mutated gene that leads to improved clone fitness but worse overall health (TBX3). 1/8

Today's #thursdaymotivation is courtesy CRI's @haozhulab.bsky.social: Congrats Gianna Maggiore for your successful #dissertationdefense! Dr. Maggiore's family and lab mates joined to celebrate. Next steps: summertime fun & finishing her M.D. 🎉 #relentlessdiscovery