In August's #EditorsChoice, Gianna Maggiore, @haozhulab.bsky.social & co showed strong clinical potential in reducing #HepatocellularCarcinoma by targeting the actin-binding protein anillin via #siRNA knockdown in #MouseModel. ⚡ doi.org/10.1242/dmm.... 📰 doi.org/10.1242/dmm....

That’s a wrap on the past 12 months, with even more #relentlessdiscovery to come in 2026. cri.utsw.edu/discoveries/ @seanjmorrison.bsky.social @rjdlab.bsky.social @haozhulab.bsky.social 🧪 #stemcells #regeneration #CancerResearch #metabolism #NYE2025 #NYE2026

ICYMI, there's a new project CRI's @haozhulab.bsky.social will collaborate on: trying to create artificial livers. Read more ⬇️ #relentlessdiscovery #CRIcollaboration 🧪 www.utsouthwestern.edu/newsroom/art...

🚨NEW PI ALERT🚨 @henrydebelly.bsky.social is in the house, and look at that *fresh* new office. Clean slate for his next #relentlessdiscovery in CRI's Tissue Regeneration Program (TRP). Onward! Read more about his new lab 👉 cri.utsw.edu/faculty/henr... 🧪 @haozhulab.bsky.social

ONLINE now in @cellpress.bsky.social: A review by CRI's @haozhulab.bsky.social about their #relentlessdiscovery and how somatic mutations are becoming a key discovery engine for disease genetics. 🧪 Read more ⬇️ www.cell.com/cell/fulltex...

A true legend. www.bcm.edu/about-us/lea...

new out in Nature, targeting FSP1 to trigger ferroptosis www.nature.com/articles/s41... www.nature.com/articles/s41...

ONLINE NOW in @science.org: DeBerardinis Lab discovers protein regulating balance between purine nucleotide production pathways. 🧪 Read more ➡️ cri.utsw.edu/deberardinis... 🔖 full breakdown ⬇️

ONLINE NOW in @science.org: @haozhulab.bsky.social discovers location matters for liver cancer's origins. 🧪 Read more ⬇️ cri.utsw.edu/zhu-lab-show... 🔖 @haozhulab.bsky.social's breakdown ➡️ x.com/Zhu_Lab/stat... #relentlessdiscovery

In this Editor's Choice, Maggiore, Zhu @haozhulab.bsky.social and colleagues reveal the high clinical potential of GalNAc-siRNA-based strategies for preventing hepatocellular carcinoma development in high-risk individuals, particularly through targeting ANLN. doi.org/10.1242/dmm.... #HCC #cancer

Introducing 2 new papers from my lab on somatic mutations in liver disease. The 1st is about a mutated gene that leads to improved clone fitness and organismal health (CIDEB). The 2nd is about a mutated gene that leads to improved clone fitness but worse overall health (TBX3). 1/8

Today's #thursdaymotivation is courtesy CRI's @haozhulab.bsky.social: Congrats Gianna Maggiore for your successful #dissertationdefense! Dr. Maggiore's family and lab mates joined to celebrate. Next steps: summertime fun & finishing her M.D. 🎉 #relentlessdiscovery