Maria Bernabeu
@mariabernabeu.bsky.social
📤 965
📥 708
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Group Leader at EMBL Barcelona. Malaria, bioengineered vascular models, blood-brain barrier
pinned post!
We are happy to show one ourt first exciting papers. We have developed a blood-brain barrier model to study the disruptive effects caused by the malaria parasite, Plasmodium falciparum. First, congratulations to the fearless
@liviapiatti.bsky.social
and
@alinabatzi.bsky.social
rdcu.be/ezBl7
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Plasmodium falciparum egress disrupts endothelial junctions and activates JAK-STAT signaling in a microvascular 3D blood-brain barrier model
Nature Communications - Here the authors show that Plasmodium falciparum egress products disrupt endothelial barrier and activate JAK-STAT and interferon type response in a 3D blood-brain barrier...
https://rdcu.be/ezBl7
about 2 months ago
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Have you ever wondered what happens with your microvessels after exposure to high temperature in fever? In this preprint former postdoc (ans soon to be PI) Viola Introini found that high temperatures cleaves glycocalyx , having severe consequences in malaria
www.biorxiv.org/cgi/content/...
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Febrile temperature enhances Plasmodium falciparum cytoadhesion by disrupting the endothelial glycocalyx
Fever, a universal host defense in infection and inflammation, paradoxically contributes to neurological complications in malaria. While febrile temperatures enhance the expression of parasite virulen...
https://www.biorxiv.org/cgi/content/short/2025.09.07.674757v1
17 days ago
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Maria Bernabeu
Nicoletta Petridou
about 2 months ago
We are searching for an enthusiastic scientist to join our team and establish annual killifish as a model system for early developmental biology and biophysics!
@embl.org
@embldbunit.bsky.social
Apply here:
embl.wd103.myworkdayjobs.com/EMBL/job/Hei..
. Please re-post 🙏
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We are happy to show one ourt first exciting papers. We have developed a blood-brain barrier model to study the disruptive effects caused by the malaria parasite, Plasmodium falciparum. First, congratulations to the fearless
@liviapiatti.bsky.social
and
@alinabatzi.bsky.social
rdcu.be/ezBl7
loading . . .
Plasmodium falciparum egress disrupts endothelial junctions and activates JAK-STAT signaling in a microvascular 3D blood-brain barrier model
Nature Communications - Here the authors show that Plasmodium falciparum egress products disrupt endothelial barrier and activate JAK-STAT and interferon type response in a 3D blood-brain barrier...
https://rdcu.be/ezBl7
about 2 months ago
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reposted by
Maria Bernabeu
bishara marzook
2 months ago
Our paper has finally graduated from pre-print to peer-reviewed, pretty much unscathed, and is out now!
www.cell.com/cell/fulltex...
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The essential host genome for Cryptosporidium survival exposes metabolic dependencies that can be leveraged for treatment
An arrayed microscopy-based CRISPR screen revealed host genes affecting multiple infection phenotypes of the intracellular parasite Cryptosporidium. Hits in the host cholesterol biosynthesis pathway a...
https://www.cell.com/cell/fulltext/S0092-8674(25)00751-2
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Pre-print alert 🚨: We have developed 2D and 3D stable iPSC endothelial-differentiation models through dox inducible ETS expression. We demonstrate endothelial identity and used these models for studying malaria pathogenesis research.
www.biorxiv.org/content/10.1...
3 months ago
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Because not all is work...Yesterday we took the opportunity that almost all lab members were around and had a super fun fanta blind testing activity courtesy of Viola Introini!
4 months ago
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reposted by
Maria Bernabeu
Nadia El Mjiyad
4 months ago
📅Next Tuesday, we will have a lunch session on ERC grants + ERC grantees
@mariabernabeu.bsky.social
and Julia Mahamid will share their experience. Infection: pathogens, hosts, and microbiomes
www.embl.org/about/info/c...
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Infection: pathogens, hosts, and microbiomes
https://www.embl.org/about/info/course-and-conference-office/events/ees25-04/
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Maria Bernabeu
Silva Pereira Lab (Parasite Vascular Interactions)
5 months ago
Here’s our latest revision of microphysiological systems in parasitology research, published in
@plos.org
#plospathogens
in collaboration with Jorge de-Carvalho (ITQB-NOVA) and
@mariabernabeu.bsky.social
. Kudos to
@mariazalmeida.bsky.social
, PhD student, for the heavy lifting of this work.
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Leveraging microphysiological systems to expedite understanding of host–parasite interactions
Microphysiological systems (MPS) replicate the dynamic interactions between cells, tissues, and fluids. They have emerged as transformative tools for biology and have been increasingly applied to host...
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1013088&?utm_id=plos111&utm_source=internal&utm_medium=email&utm_campaign=author
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Exciting work at EMBL around malaria, including our lab!
add a skeleton here at some point
5 months ago
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Thank you
@silvapereiralab.bsky.social
for letting us contribute and learn about sequestration of Trypanosma congolense and develop our first bovine microvessels. Spoilert alert: it presents much higher binding than P. falciparium to bioengineered microvessels
add a skeleton here at some point
7 months ago
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Congratulations to Dr. Rory Long, who successfully defended his thesis yesterday! Rory pulled out his project independently, and found that malaria products decrease secretion of Ang-1 in brain pericytes in complex 3Dmodels, and tested therapies that restore ang-Tie2 axis. Cannot be more proud!!!
7 months ago
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Happy to announce that we are running the third edition of the EMBL-UNESCO residency on infection biology. If you are an African female scientist and would like to do a research stay at EMBL, my lab is a possible hosting group. Deadline March 31st!
www.embl.org/about/info/s...
add a skeleton here at some point
7 months ago
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reposted by
Maria Bernabeu
8 months ago
To the Cell BIology of the Neuron Community out there! The Deadline for our
meetings.embo.org/event/25-cel...
EMBO workshop is approaching! Register by March 1st and join us in Crete!
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Less than one month left to submit your abstract!
add a skeleton here at some point
8 months ago
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The
@mimsumea.bsky.social
,
@scilifelab.se
and
@embl.org
workshop "infection across scales" was a success. Special thanks to
@mimsumea.bsky.social
Oliver and Nora for being fantastic hosts and organizing once in a lifetime networking activities.
add a skeleton here at some point
8 months ago
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Maria Bernabeu
EMBL
8 months ago
The Kowalinski group's latest study on trypanosome parasites reveals significant differences between the trypanosomal and human nuclear cap-binding complex. This key player in cellular RNA metabolism could be a potential target for novel anti-parasitic drugs.
www.embl.org/news/science...
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Maria Bernabeu
Siegenthaler Lab
8 months ago
TODAY is the last day of abstract submission for
@cshlmeetings.bsky.social
Brain Barriers 2025...get them in so you will not miss presenting at one of the best CNS barriers meeting in the world! 🧠 + 🚧
#cshlbbb
@caromenard666.bsky.social
@ayalbenzvi.bsky.social
add a skeleton here at some point
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reposted by
Maria Bernabeu
Baptiste Lacoste
9 months ago
Not all astrocytes regulate blood-brain barrier integrity, but those expressing Dmp1 apparently do !
#cerebrovascular
#BloodBrainBarrier
www.science.org/doi/10.1126/...
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Regulation of blood-brain barrier integrity by Dmp1-expressing astrocytes through mitochondrial transfer
A subset of astrocytes expressing Dmp1 helps maintain blood-brain barrier by transferring mitochondria to endothelial cells.
https://www.science.org/doi/10.1126/sciadv.adk2913
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We are very excited to announce a new
@events.embl.org
conference with a general focus on all infections with the goal to foster discussions across researchers working on multiple pathogens. We couldn't find a conference as such in Europe, so we decided to organize it 😊
www.embl.org/about/info/c...
9 months ago
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Maria Bernabeu
FMI science
9 months ago
📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at:
www.fmi.ch/education-ca...
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Maria Bernabeu
EMBL Events
9 months ago
🦟🌍 Join us for the 21st edition of
#EMBLMalaria
as we strengthen partnerships, share insights, and drive innovations to combat malaria's toll and advance global health. 📅 20 – 22 May 2025 📍 EMBL Heidelberg and Virtual 📝 Submit abstract by 25 Feb 👉🏻
s.embl.org/bmp25-01-bl
#malaria
#epidemiology
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Maria Bernabeu
Parc de Recerca Biomèdica de Barcelona
9 months ago
✅ El grup liderat per
@mariabernabeu.bsky.social
a l’
@embl.org
ha creat microvasos cerebrals en un xip per provar anticossos contra proteïnes virulentes de la malària 🦟 i observar els seus efectes. Llegeix la notícia sencera aquí 👇
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Microvasos cerebrals per entendre els anticossos contra la malària - El·lipse
El grup liderat per Maria Bernabeu a l’EMBL Barcelona ha creat microvasos cerebrals en un xip per provar anticossos contra proteïnes virulentes i observar els seus efectes.
https://ellipse.prbb.org/ca/microvasos-cerebrals-per-entendre-els-anticossos-contra-la-malaria/
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Our lab is interested in supporting EIPOD-linC postdoc applications in collaboration with
@khaase.bsky.social
on a in vitro placental malaria model and
@simonemattei.bsky.social
on developing in tissue cryo-EM imaging of P. falciparum-endothelial interactions. If you are interested, email or DM.
10 months ago
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Congratulations
@liviapiatti.bsky.social
on a fantastic thesis and great defense. Super proud of you!
10 months ago
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Maria Bernabeu
Xavier Trepat
10 months ago
Pre-announcing the EMBO/EMBL symposium "Mechanobiology Across the Tree of Life", Heidelberg, 9-12 June 2026. It is still very very far away, but save the date 🗓️. With Alba Diz-Munoz,
@nicolettapetridou.bsky.social
, Kirsty Wan
@micromotility.bsky.social
, Enrique Rojas.
www.embl.org/about/info/c...
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Mechanobiology across the tree of life
https://www.embl.org/about/info/course-and-conference-office/events/ees26-06/
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Maria Bernabeu
Andy Aydın-Aitchison
10 months ago
Academics wanting to 'verify' their Bluesky profile as genuine might give an ORCID identifier in their profile and link back to their Bluesky profile from ORCID.
#AcademicSky
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Happy and proud that EMBL has now a Bluesky account! Follow to get to hear about all our colleagues exciting science and initiatives
add a skeleton here at some point
10 months ago
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Maria Bernabeu
Luisma Escudero
10 months ago
Oye
@larevueltatve.bsky.social
que estoy preparando un hilo para convenceros de que sería un acierto llevarnos a
@claragrima.bsky.social
y a mí para contaros la historia del descubrimiento de los
#escutoides
. Os garantizamos que no tenemos ningún contrato en exclusiva con “otra gente” y vamos fijo.
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Maria Bernabeu
Grace Lindsay
10 months ago
When I will respond to your email
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Thrilled that my first post here is about a great team effort led by Evelien Bunnick, Thomas Lavstsen, and Louise Turner. We identified broadly reactive mAb that inhibit parasite binding to PfEMP1 asaociates with severe maria.
www.nature.com/articles/s41586-024-08220-3
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Broadly inhibitory antibodies to severe malaria virulence proteins - Nature
Two broadly reactive and inhibitory human monoclonal antibodies against the malaria parasite Plasmodium falciparum have been characterized, providing insights into immunity, prevention and treatm...
https://www.nature.com/articles/s41586-024-08220-3
10 months ago
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reposted by
Maria Bernabeu
Eileen Furlong
10 months ago
My first post on Blue Sky - moving over ! For all post-docs out there - fantastic opportunity @EMBL. Independent group leader position: Core funding, state-of-the-art core facilities, access to fantastic Ph.D. students, and of course amazing colleagues. Please apply
www.embl.org/jobs/positio...
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EMBL Jobs
We offer a wide range of challenging scientific and non-scientific positions at all of our European locations and encourage applications from international candidates at all career levels.
https://www.embl.org/jobs/position/HD02741
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Maria Bernabeu
Lars-Anders Carlson
11 months ago
Repost appreciated: Open
#PhDposition
in my group! Join us in Umeå, 🇸🇪 to uncover how arboviruses remodel the cellular interior. In situ
#cryoET
with great
#virology
and
#biophysics
collaborators. Customisable project. Application deadline 15 December. More info:
www.carlsonlab.se/join/
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