Lars-Anders Carlson
@lacarlson.bsky.social
📤 1863
📥 284
📝 270
Structural virology group leader at Umeå University, Sweden.
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Lars-Anders Carlson
c0nc0rdance
1 day ago
This is the "SEA SHEEP" (Costasiella kuroshimae) & it took the old axiom: "you are what you eat" VERY literally. It eats algae & rather than just digest them, it harvests the chloroplasts & becomes PHOTOSYNTHETIC. Solar slug! Also, some of its cousins can rip their own heads off.
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Ben Barad
2 days ago
Online today, the journal version of our (
@nanigrotjahn.bsky.social
@attychang.bsky.social
@mmedina300kv.bsky.social
) manuscript from earlier this year describing membrane thickness measurement in cells with
#teamtomo
!
rupress.org/jcb/article/...
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Surface Morphometrics reveals local membrane thickness variation in organellar subcompartments | Journal of Cell Biology | Rockefeller University Press
Medina, Chang et al. introduce a new method based on the Surface Morphometrics pipeline to measure global and local thicknesses of organellar membranes fro
https://rupress.org/jcb/article/225/3/e202505059/278755/Surface-Morphometrics-reveals-local-membrane
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Wecome back UK! The end of Erasmus student exchanges between EU-UK was one of the saddest consequences of Brexit from my point of view. Glad to see that this has been re-enabled!
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12 days ago
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RCSB Protein Data Bank
13 days ago
PDB-101 has highlighted the structural biology of athletics and well-being throughout 2024-2025. What topic should we explore in 2026?
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PDB101: Browse: Peak Performance
PDB-101: Training, Outreach, and Education portal of RCSB PDB
https://pdb101.rcsb.org/browse/peak-performance
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Jess Calarco
15 days ago
This was *entirely* preventable.
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Ben Barad
15 days ago
Hopefully as image processing in cryoET advances we can see concomitant improvements in benchmarking and validation - so we don't end up imagining features of cells that aren't there!
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Alister Burt
16 days ago
pretty unambiguous experience in the replies - something is up!
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Alister Burt
17 days ago
RELION 5 3D refinement on tomo data often seems to struggle to align objects that old school STA packages handled no problem... does this match everyones experience or is this a me problem?
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Oli Clarke
17 days ago
🤯
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Juergen Koefinger
18 days ago
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EMBL
18 days ago
Congratulations, Julia Mahamid! Julia Mahamid receives the
@dfg.de
Leibniz Prize for her work on structural cell biology!
#LeibnizPreis
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Daily Dose of Philosophy
18 days ago
Agree?
#philosophy
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Review Commons
18 days ago
One review. Many journals. Less redundancy. Check out this conversation with our head Dr. Thomas Lemberger on the vision behind
@reviewcommons.org
and what it means for authors and journals alike
@embopress.org
@embo.org
www.embo.org/people/revie...
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Review Commons: rethinking peer review – Features – EMBO
A conversation with Thomas Lemberger, lead of the Review Commons initiative and Head of Open Science Implementation at EMBO.
https://www.embo.org/people/review-commons-rethinking-peer-review/
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Must be time for my Christmas break because I am clearly hallucinating.
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18 days ago
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ERC-CoG for microbiologist Barbara Sixt. Umeå microbial research scores again. Congrats, Barbara!
www.umu.se/en/news/eu-f...
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EU funding secures continued research on chlamydia
ERC provides secured funding for five years to Barbara Sixt's research on chlamydia.
https://www.umu.se/en/news/eu-funding-secures-continued-research-on-chlamydia_12152269/
18 days ago
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EMBO
19 days ago
The EMBO Gold Medal 2025 was awarded to Tanmay Bharat and David Bikard:
https://www.embo.org/press-releases/embo-gold-medal-2025-awarded-to-tanmay-bharat-and-david-bikard/
🧪 At
#CellBio2025
, the EMBO Gold Medal was handed over to David Bikard in recognition of his pioneering work on
#GeneEditing
.
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Notably, 14 pt size. I think this great idea should be implemented for Swedish grants, without changing the page limit. Would lessen the burden.
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19 days ago
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Vivien Horvath
22 days ago
📣We are looking for a Project Assistant to join my group at the Wallenberg Center for Molecular Medicine at Umeå University. Join us if you are interested in transposable elements, epigenetics and human brain aging. 🧠🧬 Dont hesitate to reach out with any questions! 📣
umu.varbi.com/en/what:job/...
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Project Assistant
The Department of Medical and Translational Biology at the Faculty of Medicine is now seeking a project assistant for a research project related to human brain aging. The position is full-time and lim
https://umu.varbi.com/en/what:job/jobID:875572/
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We will announce a
#postdoc
opening in January. Cryo-ET and virus replication. If you're interested you can DM or email me already now. More info will follow!
21 days ago
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Sjors Scheres
22 days ago
Asking for only the top-X best publications on CVs for jobs or grant proposals would focus more on quality than on quantity.
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Carsten Sachse
25 days ago
Really happy to see the work (
doi.org/10.1038/s414...
) published. Here, we show the full-length helical cryo-EM structure of p62/SQSTM1 and first cryo-ET visual of p62 positive structures inside the cell.
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Structural organization of p62 filaments and the cellular ultrastructure of calcium-rich p62-enwrapped lipid droplet cargo - Nature Communications
The selective autophagy receptor p62/SQSTM1 is organized in a structured double helical filament in vitro, the cryo-electron tomographic images in ATG5 knockdown conditions reveal Ca-rich layers of p6...
https://doi.org/10.1038/s41467-025-66785-7
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cryoEM papers
24 days ago
Microsecond Time-Resolved Cryo-EM Based on Jet Vitrification
pubmed.ncbi.nlm.nih.gov/41332690/
#cryoem
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Daniel Hurdiss
25 days ago
My favourite experiment in the whole study is the negative-stain polyclonal epitope mapping we did using elephant serum, affectionately known in the lab as Ellie-EMPEM 😄
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The prestigious Wallenberg Academy Fellow awarded to
@maxrenner.bsky.social
and to the newest groupleader in my department, Andreas Kohler. Congrats friends!
@mbb-umu.bsky.social
www.umu.se/en/news/thre...
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Three Umeå researchers appointed Wallenberg Academy Fellows
Three researchers have been appointed Wallenberg Academy Fellows by the Knut and Alice Wallenberg Foundation.
https://www.umu.se/en/news/three-umea-researchers-appointed-wallenberg-academy-fellows_12152121/
26 days ago
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Makes me think of some university committees I have spent time in...
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26 days ago
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Microbetv
27 days ago
This past year, science has kept us all on our toes with new outbreaks, new discoveries & new questions. If our work has helped you make sense of the world this year, we hope you’ll consider supporting it. Independent science education matters. Now more than ever!
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Daniel Hurdiss
27 days ago
Honoured to be selected as one of this year’s EMBO Young Investigators! Grateful to my team and colleagues for all their support, and excited about the opportunities this will create for my group and for our work in structural virology.
www.embo.org/press-releas...
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Jeremy Berg
27 days ago
New York Times article on science funding with some depressing but familiar curves with interactive graphics.
www.nytimes.com/interactive/...
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The U.S. Is Funding Fewer Grants in Every Area of Science and Medicine (Gift Article)
A quiet policy change means the government is making fewer bets on long-term science.
https://www.nytimes.com/interactive/2025/12/02/upshot/trump-science-funding-cuts.html?unlocked_article_code=1.5k8.-Yuf._rLIqKb0F-aK&smid=url-share
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Very cool to see our Umeå colleague and fellow structural virologist raking in a major grant. Congrats
@maxrenner.bsky.social
!
www.umu.se/en/news/umea...
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Umeå researchers aim to reveal how viruses build their factories
Max Renner explore how viruses copy themselves – to help stop future outbreaks.
https://www.umu.se/en/news/umea-researchers-aim-to-reveal-how-viruses-build-their-factories_12152022/
27 days ago
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Science Magazine
27 days ago
Science’s 2024 Breakthrough of the Year was lenacapavir, an injectable drug that demonstrated remarkable success at preventing HIV infection with one shot every 6 months. Learn more about last year's
#BOTY
on
#WorldAIDSDay
:
https://scim.ag/48pk7zZ
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WHO
28 days ago
Today is
#WorldAIDSDay
With Lenacapavir or LEN, a new drug WHO recommends to protect people at risk of
#HIV
instead of taking daily pills, people can now get injections every 6 months. At the time where funding for HIV is limited, this new drug could mean fewer new infections & more lives saved.
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Magdalena Skipper
28 days ago
The world has lost a giant of virology, molecular biology and science advocacy David Baltimore’s obituary by Stephen Goff
www.nature.com/articles/d41...
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David Baltimore obituary: virologist whose enzyme discovery transformed understanding of cancer and HIV/AIDS
The protein, reverse transcriptase, has become an essential tool for making DNA copies of RNA.
https://www.nature.com/articles/d41586-025-03862-3
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France-BioImaging
28 days ago
"Cell la vie!" meeting is back!📅 The French Society for Cell Biology is pleased to announce that the next edition will take place on October 21-23, 2026 in Paris. This year will focus on the needs & challenges to explore the life sciences with an highlight on the role of microscopy. 🔬 Stay tuned!
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Our World in Data
28 days ago
Farmed pigs weigh as much as all of the world’s whales, orcas, sea otters, seals, and dolphins combined. All the dogs in the world, including pets and feral dogs, weigh as much as all wild mammals on land.
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bioRxiv Microbiology
28 days ago
Nanoscale imaging of native symbiotic animal tissue using amultimodal large volume imaging pipeline for cryo-electrontomography
https://www.biorxiv.org/content/10.1101/2025.11.30.691379v1
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I had missed this paper! Will definitely have a look at it. Congrats, Naoko and all other authors!
www.nature.com/articles/s41...
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In situ structural mechanism of epothilone-B-induced CNS axon regeneration - Nature
A combined cryo-electron tomography and cryo-electron microscopy pipeline was developed to inflict axonal damage and monitor the cellular response induced by epothilone B, revealing that mic...
https://www.nature.com/articles/s41586-025-09654-z
28 days ago
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Is LLPS the cell biologists' equivalent of the FSC discussions in cryo-EM? Recent threads on here make me think that.
29 days ago
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cryoEM papers
30 days ago
ExoSloNano: multimodal nanogold labels for identification of macromolecules in live cells and cryo-electron tomograms
pubmed.ncbi.nlm.nih.gov/41315814/
#cryoem
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Mart Krupovic
30 days ago
Explicit description of viral capsid subunit shapes by unfolding dihedrons by Ryuya Toyooka et al.
www.nature.com/articles/s42...
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Explicit description of viral capsid subunit shapes by unfolding dihedrons - Communications Biology
A proposed geometric framework describes and classifies all possible protein subunit shapes in viral capsids through spherical tiling theory, revealing different interaction patterns based on subunit ...
https://www.nature.com/articles/s42003-024-07218-x
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The Banfield Lab
about 1 month ago
Out now in Nature Communications: Convergent evolution of viral-like Borg archaeal extrachromosomal elements and giant eukaryotic viruses
www.nature.com/articles/s41...
@luisvalentin.bsky.social
@lingdong-shi.bsky.social
@martianmicrobe.bsky.social
@mschoelmerich.bsky.social
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Convergent evolution of viral-like Borg archaeal extrachromosomal elements and giant eukaryotic viruses - Nature Communications
Borgs are large extrachromosomal elements of anaerobic methane-oxidizing archaea. Here, via in silico protein structure prediction of ~10,000 Borg proteins, the authors reveal that Borgs share numerou...
https://www.nature.com/articles/s41467-025-65646-7
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Katherine Stiles
about 1 month ago
·
#AcademicSky
· The European Research Council is launching €7m Plus Grants for ambitious, long‑term research — open to researchers at any career stage but limited to about 30 awards; current ERC grantees and applicants are ineligible, reports
@clanicholson.bsky.social
.
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ERC’s new €7m Plus Grants open to researchers at any career stage - Research Professional News
European Research Council president describes scheme as part attempt to lure US talent
https://www.researchprofessionalnews.com/rr-news-europe-horizon-2020-2025-11-erc-s-new-7m-plus-grants-open-to-researchers-at-any-career-stage/
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Abdou Rachid Thiam
about 1 month ago
And the saga continues! Our collaborative work with outstanding Justin Korfhage & Thomas Melia’s lab in PNAS shows that ATG2A transfers triglycerides and does so bidirectionally! An exciting twist in our understanding of lipid transport. Definitely worth a deep read:
www.pnas.org/doi/10.1073/...
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Juanma García-Arcos
about 1 month ago
New paper from the
@rouxlab.bsky.social
on Nature Communications! We study how membrane tension is spatially organized in cells. Using the mechanosensitive probe Flipper-TR to visualize tension across the plasma membrane of adherent cells and to dissect the conditions needed for a gradient to happen
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Randall Munroe
about 1 month ago
Geologic Core Sample
xkcd.com/3171/
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Valeria Lulla
about 1 month ago
📢Astrovirus polyprotein processing is finally uncovered - these viruses use peculiar dual cleavage sites around their protease! Led by a talented PhD student, David Noyvert, this work provides a map of astrovirus genomes. Great collaboration with
@emmottlab.bsky.social
@leandroxneves.bsky.social
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Viral protease-mediated polyprotein processing in human astroviruses
Positive-sense RNA viruses often encode large polyproteins that are proteolytically processed by viral and host proteases into functional replication proteins. Astroviruses infect intestinal and neuro...
https://www.biorxiv.org/content/10.1101/2025.11.24.690148v1
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Ian M. Mackay, PhD (he/him) 🦠🤧🧬📑🦟🧀
about 1 month ago
Frikkin amazing stuff.
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cryoEM papers
about 1 month ago
Ballistic Microscopy (BaM)
pubmed.ncbi.nlm.nih.gov/41279100/
#cryoem
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Fabien Burki
about 1 month ago
Each such discovery is a game changer for our understanding of eukaryote evolution, and this paper is no exception. Meet Solarion, which displays yet again novel types of subcellular structures. Congrats to all authors on a fascinating story.
#protistsonsky
www.nature.com/articles/s41...
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Rare microbial relict sheds light on an ancient eukaryotic supergroup - Nature
The discovery of an unusual protist named Solarion arienae, which has a mitochondrial genome with some intriguing features, provides insight into the early radiation of eukaryotic groups.
https://www.nature.com/articles/s41586-025-09750-0
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Reminder of the importance of flu, if you needed one. I'm intrigued by the difference between some neighbouring countries. Is the difference between Norway and Sweden likely to be due to differences in vaccination programmes?
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about 1 month ago
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Daniel Hurdiss
about 1 month ago
It’s been a while since I put together the Structural Virology starter pack, and I’m sure some new folks have joined Bluesky since then. There’s still plenty of space to fill, so if you’d like to be added to the list just let me know.
#virology
#cryoEM
go.bsky.app/Qxv95BL
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