The appropriations bill that includes NIH is being finalized. The Senate bill includes a bipartisan amendment from Senators Capito (WV) and Baldwin (WI) limiting multi-year funding of grants. The House version does not and OMB has issued a veto threat if the House includes such language. 1/3

Check out this story! Atlantic writer Alexandra Petri visited my lab and played with some fruit flies and human organoids as she wrote about experiencing things that were affected by government cuts. www.theatlantic.com/magazine/202...

I'm so excited that @christ3na.bsky.social 's paper describing temporal control of photoreceptor development in human organoids is out at Genes and Dev and we got the cover! genesdev.cshlp.org/content/40/1... genesdev.cshlp.org/content/40/1...

We noticed that a plate of C. elegans worms, under starvation conditions, forms stable living spatial structures, which we dub "worm webs". These webs seem to be scaffolded by an excreted substance from living or dead worms, which we dub "wormstuff". www.focolab.org/post/worm-we...

Happy to announce the publication of our foray into studying what happens to the transcriptomes of nuclei when cells fuse to form a syncytium. More to follow in the coming few years. One really wonderful thing about the Company of Biologists is that's it's free to publish there for my university!

We have had a lot of requests for the protocol for single-nucleus RNA-seq of adult C. elegans neurons that our lab developed - I hope that you find this helpful! 🧪 #Celegans www.sciencedirect.com/science/arti...

Now in print: tour de force mitonuclear epistasis study in C. elegans. Start to finish, vision and execution, 100% Tuc Nguyen @tuchmnguyen.bsky.social

A new community-driven lab handbook for reducing conflict and creating more positive and equitable work environments gets strong support from a survey of 200 researchers. buff.ly/K7CGFLV

I’ll be one of the panelists! I hope to see you there!

Our Lab @ NCBS, Bangalore is hiring PhD students! If you’re excited about cell & developmental biology, tissue mechanics, and imaging — come join us! We use C. elegans to uncover how forces shape organs 🧫🔬 CSIR/DBT/ICMR fellowship holders encouraged to apply!Apply 👉 lnkd.in/gr9EUHnp

I taught Genetics again this year. We need to include discussion of the problematic history of our field, especially as the claims of eugenics are once again centered in our political discourse. Last year I wrote this piece, explaining my reasoning and approach 🧪 1/n www.cell.com/trends/genet...

#Celegans adapts to starvation & other stressors by transiting through the quiescent #dauer stage, but how? This study shows that TOR activity is inhibited by AMPK & a novel RNA-binding helicase in the #GermLine during dauer, preserving developmental quiescence @plosbiology.org 🧪 plos.io/48NEHvc

We built this site to allow you to probe our single-nucleus RNA-seq data for adult #Celegans neurons (wt & daf-2 herms, and wt males v herms): cestaan.princeton.edu and a microPub about how to use it: www.micropublication.org/journals/bio... We hope the #Celegans community finds it useful! 🧪

Something to be thankful for ~ our paper on the intersection of fatty acid metabolism and host-pathogen response in #Celegans is now published in DMM! journals.biologists.com/dmm/article/...

Scientists must learn to join larger pro-democracy and people's movements, coalitions. Our science training may not have prepared us for such work, but we can no longer sit in the safety of our labs and expect the world to get better My book review @thelancet.com www.thelancet.com/journals/lan...

working up a little cell/worm counter. ~$40 of adafruit parts (plus some keyboard switches, 3d printing, and minor soldering). Next steps are wifi/bt communication. currently envision counting and ethotiming modes, but if any c. elegans friends have ideas, I’d be happy to consider them.

What happens to the germline under heat stress? New study in #G3journal shows how wild-type #Celegans increase their germline apoptosis levels from the physiological baseline in response to moderate temperature stress to maintain fertility. buff.ly/SXdoQFA

Read this inspiring perspectives coauthored by the Worm Resource directors and worm Nobel Laureates! 4 Nobel Prizes and how they were enabled by major NIH-supported research resources (the Caenorhabditis Genetics Center, WormBase, and WormAtlas) www.pnas.org/doi/10.1073/...

Congratulations to Karp lab student Vusani Ntuli who won the Best Poster Award at the Central Michigan University Biology Undergraduate Research Symposium yesterday! I’m so proud of him and of the other 5 Karp lab presenters.

SAVE THE DATE! Stoked to organize the 2026 Santa Cruz Developmental Biology Meeting with @rashmi-priya.bsky.social, @lowelab.bsky.social, and Shelbi Russell. Come learn about Biomedicine, Biomechanics, and the Biosphere, August 24-28, 2026. Registration dates, etc., coming soon! Please RT

Happy International Day of LGBTQIA+ People In STEM! How are you celebrating it? #LGBTQSTEMDay #PrideInSTEM

New preprint! It turns out you can integrate arrays with super high efficiency using PhiC31. www.biorxiv.org/content/10.1...

C. elegans enthusiasts- save the date for two consecutive C. elegans meetings, taking place in Bordeaux, 29 June–3 July 2026. Abstract submission will open around January, with many opportunities for oral presentations. Check out our website for more details: ceneuroeuro2026.sciencesconf.org.

Make males live more than 400% longer and prevent sexual disfunction late in life?! We're down with it. Our latest preprint: Disruption of the insulin signaling pathway in C. elegans dramatically increases male longevity and enhances reproductive health late in life. www.biorxiv.org/content/10.1...

Well reported story on the PBS News Hour about science cuts and the ongoing and potential brain drain. www.youtube.com/watch?v=yLvO... Thanks to Terrance Tao and other scientists at various career stages for having the courage to speak out. Watch and share! 1/7

Nektarios Tavernarakis on why curiosity-driven research, not focusing on application, is fundamental to problem solving and requires government support in @emboreports.org doi.org/10.1038/s443...

Cool! Thanks @embojournal.org for this great News and Views on our recent work characterizing how a conserved protein complex times C. elegans molting! www.embopress.org/doi/full/10.... Such a fun collaboration with @labgrosshans.bsky.social @partchlab.bsky.social

For what it’s worth, The Wyoming Worm lab has funding for 5 years along with exciting projects with solid foundations. We are is still looking for capable, dedicated, and fun-to-work-with lab members at all career stages. [email protected] scholar.google.com/citations?us...

And the next one: dx.doi.org/10.1038/s44318-025-00585-z . Super-fun collaboration with @partchlab.bsky.social & @gotworms.bsky.social to find similarities between developmental and circadian clocks – supported by @fmiscience.bsky.social Facilities and, financially, @snsf.ch and @erc.europa.eu . 1/n

This is a powerful account from a PhD student whose fellowship was terminated by NIH because it was part of a "diversity" program without any other considerations or understanding of what the program or the students were actually doing. undark.org/2025/10/09/o... 1/2

Watch Lucas' amazing artistic/musical rendition of C. elegans larval development and our work on developmental timing and molting here youtu.be/-hGHYRvw87w and read on his inspiration and challenges below

An excellent piece by Joachim Frank, 2017 Nobel Laureate in Chemistry, about how we must resist the Trump Administration's crackdown on universities. www.usnews.com/opinion/arti...

C. elegans is a little animal with sexually dimorphic tails. Fitch lab does wonderful work on the evolution and transcriptional regulation of tail tip morphogenesis in nematodes.

Paper alert! doi.org/10.1038/s443... - "A scheduler for rhythmic gene expression". We show how 9 txn factors suffice for rhythmic gene expression of thousands of genes with any phase or amplitude in #Celegans larvae (and also look at the tissues where oscillations happen) 1/n

I'm doing another print run of these "Biology is Bigger than Binaries" shirts! Back, quite literally, by popular demand. Bullying works, sure, but so does a bunch of nice cutie patooties politely asking! Order 'em now, I'll mail 'em in early November. SquidFacts.net

Very excited to share our very exciting story on how misinherited chromatin affects individual cells to cause a behavior defect in C. elegans (a thread👇) www.pnas.org/doi/10.1073/...

I have been trying to get this published as an op-ed, but I am going to post it here since I think it is timely in light of the "consent" extortion events. Deafening Quiet from the Scientific Establishment jeremymberg.github.io/jeremyberg.g... 1/14

Hi fellow C. elegans scientists, I've made a few videos that may be of use for new trainees working in worm labs. Hoping to add more in the future, but figured I'd share this resource as is in case it's helpful :) www.youtube.com/@Workingwith...

IMO this hasn't gotten enough attention: a recent memo at NIH announces that peer review will be devalued in determining which grants get funded, granting more power to political appointees to make decisions based on the admin's whims over scientific merit kffhealthnews.org/news/article...

Worm peeps: nominate a newly minted PhD for the Sydney Brenner Thesis Award! #celegans

I wrote something on developmental biology and disability and put it up on the node last night: thenode.biologists.com/developmenta... I've been nervous to share because some of it veers a bit personal but they are thoughts that won't stay quiet. Would love to know what people think about it!

It's online! In this series of perspectives @dev-journal.bsky.social, yours truly talks about the exciting open questions and many things to do in the field of dev bio and neuroscience #DevBio🧪 #PIsOfTomorrow journals.biologists.com/dev/article/...

#DBFeature Connecting developmental biology to societal and political issues in the classroom boosts student engagement and critical thinking, fostering a deeper understanding of both science and social justice. - Megan Morgan Hoffman #SpecialIssue on teaching #DevelopmentalBiology for #SocialChange

Continuing efforts to hurt the research pipeline, the very late NSF GFRP solicitation no longer allows 2nd year PhD students to apply. Lots of these students chose not to apply last year because they were told they would have a better change once in their thesis lab www.nsf.gov/funding/oppo...

Very excited to share this finding from my postdoctoral work that is now published in #ScienceAdvances. We show how the gut’s epithelium modifies enteric behaviors during nutritional adversity via distinct peptidergic signaling axes. www.science.org/doi/10.1126/... Thread ⬇️ (1/n)

C. elegans is a real animal and we set out to understand how it comes to have its distinctive biogeography. Its ancestral center of diversity is in the higher elevation forests of Hawaii. Its closest relatives are spread across east Asia. Did they travel from Asia? [Preprint 🧵]

ADD YOUR THOUGHTS ON LIMITING STUDENT VISA TO FOUR YEARS Comment period ends September 29th www.federalregister.gov/documents/20... 1/2

The 2025-2026 #aECM club schedule is now posted on our website, where you can also find the link to sign up for access. I’m looking forward to lots of great talks and discussions! sundaramlab.com/blog/aecm-cl...

Save the McNair Scholars Program! Funding could end on Sept 30th! #SaveMcNair #McNairScholars #TRIOWorks