Meera Sundaram
@meera-sundaram.bsky.social
š¤ 1267
š„ 460
š 249
Worms, Tubes, Matrix. In Philly
#Celegans
#aECM
Editor at GENETICS
pinned post!
#aECM
(apical extracellular matrix) is a subset of
#ECMatrix
that is distinct from stromal matrices or basement membranes. Anybody out there studying
#mucins
#ZPproteins
#cuticle
#glycocalyx
#surfactant
or the like? We need to find each other and start talking!
about 1 year ago
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Max Heiman
5 days ago
Vote worm! by
@wormkaiden.bsky.social
Kaiden Power in our lab .. although I've got to say those Malpighian tubules are looking sharp too!
add a skeleton here at some point
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W. Brent Derry
13 days ago
Another great resource for the worm pickers.
add a skeleton here at some point
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#CellBio2025
Note that the app wonāt list you as an attendee unless you manually add yourself to the list using your Profile link (under the little wheelie tool)
@peiferlabunc.bsky.social
@danstarrucdavis.bsky.social
17 days ago
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#aECM
at
#CellBio2025
On Sunday, the Sundaram lab will have 2 posters on
#Celegans
aECM - boards 223 and 225
18 days ago
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#aECM
at
#CellBio2025
Deepak Krishnamurthygave a fascinating talk about how choanoflagellates use glycans to help build 3D basket structures or « lorica » around themselves
18 days ago
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#CellBio2025
Andy Garcia gave a great talk about Archaea and how their unique lipids help them survive in extreme environments - excellent science communication that fully engaged this non-expert!
18 days ago
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bioRxiv Genetics
19 days ago
WormTagDB: A Systematic Survey of Endogenously Tagged Proteins in C. elegans and Roadmap Towards the Tagged Proteome
https://www.biorxiv.org/content/10.64898/2025.12.02.691955v1
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The
#CellBio2025
app is telling me I donāt have any friends! ššš
20 days ago
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Meera Sundaram
Mike Rollin
21 days ago
I so needed this thread, I think you do too!
add a skeleton here at some point
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Peter Norman
over 1 year ago
Late to the party, but I think of this one from time to time.
www.theonion.com/affluent-whi...
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Affluent White Man Enjoys, Causes The Blues
HIGHLAND PARK, ILāSteve Smalls, a senior vice-president at Chicago's Alliance Manufacturing, the world's largest producer of industrial refrigeration systems, is a self-described "blues nut."
https://www.theonion.com/affluent-white-man-enjoys-causes-the-blues-1819565488
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Eric
over 1 year ago
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Every day there is something š¤¬
21 days ago
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JoAnn Trejo
22 days ago
www.nytimes.com/interactive/...
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The U.S. Is Funding Fewer Grants in Every Area of Science and Medicine
A quiet policy change means the government is making fewer bets on long-term science.
https://www.nytimes.com/interactive/2025/12/02/upshot/trump-science-funding-cuts.html?campaign_id=34&emc=edit_sc_20251202&instance_id=167351&nl=science-times®i_id=53008313&segment_id=211676&user_id=d250488560eed2a184381663ee562839
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Meera Sundaram
MadScientist
23 days ago
I find it really sad that a society whose constituents generate hundreds of beautiful scientific and artistic images both by using a scope and grabbing a pencil and paper, uses AI slop to promote something š§Ŗ Image description: an AI-generated advent calendar with a bunch of model organisms
add a skeleton here at some point
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Meredith Shiner
26 days ago
Columbia and Northwestern are the academic homes to the most prestigious journalism schools in the country and they are the two universities that caved to the Trump administrationās extortion demands that are directly connected to the First Amendment. Just gonna sit with that for a while.
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Proceedings of the National Academy of Sciences
28 days ago
All hail Caenorhabditis elegans, one of the most researched organisms on Earth. Collaborative data sharing in the nematode research community led to four Nobel Prize-winning discoveries about human development and disease. In PNAS:
https://ow.ly/uNqU50Xyj4e
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filmadelphia.org/movies/rrr/
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RRR - Philadelphia Film Society
Thereās never been a better time for friends, family, and loved ones to come together for the decadent and action-packed feast that is S.S. Rajamouliās RRR. Whether itās your first time dining with us or youāre coming back for seconds (or more), join PFS for our 21st (!!!) screening of this mind-blowing spectacle about the power of friendship.
https://filmadelphia.org/movies/rrr/
28 days ago
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It still hasnāt been cold enough for a full ginkgo drop, but itās startingā¦
#Philly
28 days ago
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Meera Sundaram
Nature
28 days ago
āThere were some cells in there that were very messed upā In a technological tour-de-force, researchers have sequenced the whole genomes of more than 100 individual cells from one 74-year-old man
go.nature.com/44yj4MN
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We are all mosaics: vast genetic diversity found between cells in a single person
Technical advances allow researchers to trace the genetic changes that occur over time.
https://go.nature.com/44yj4MN
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Oded Rechavi
30 days ago
Read this inspiring perspectives coauthored by the Worm Resource directors and worm Nobel Laureates! 4 Nobel Prizes and how they were enabled by major NIH-supported research resources (the Caenorhabditis Genetics Center, WormBase, and WormAtlas)
www.pnas.org/doi/10.1073/...
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#aECM
folks take note!
add a skeleton here at some point
29 days ago
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Meera Sundaram
Surojit Sural
30 days ago
From nematode to Nobel: How community-shared resources fueled the rise of Caenorhabditis elegans as a research organism - a perspective written by 11 scientists, six of whom are Nobel laureates
www.pnas.org/doi/10.1073/...
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PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
https://www.pnas.org/doi/10.1073/pnas.2522808122
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Meera Sundaram
Jeremy Berg
about 1 month ago
I have posted about this before, but... Researchers at Pitt School of Public Health (with NIH funding) developed Project Tycho where they digitized reportable disease data from across the country going back to ~1900.
graphics.wsj.com/infectious-d...
1/6
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Battling Infectious Diseases in the 20th Century: The Impact of Vaccines
The number of infected people, measured over 70-some years and across all 50 states and the District of Columbia, generally declined after vaccines were introduced.
https://graphics.wsj.com/infectious-diseases-and-vaccines/
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Anne Lutz Fernandez
about 1 month ago
"If Trumpās first term was marked by a level of graft and self-dealing that would have embarrassed a Tammany stalwart, then his second term seems to be an explicit effort to outpace his previous record and set a new high-water mark for political corruption in the [US]."
#GiftLink
#GiftArticle
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Opinion | The White House Gold Rush Is On
https://www.nytimes.com/2025/11/19/opinion/rolex-gold-trump-corruption.html?unlocked_article_code=1.2U8.DYZH.1viRGsgPNtZr&smid=url-share
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The Meshwork
about 1 month ago
Our November
#TheMeshwork
seminar dives into proteomics & proteolytic ECM remodeling in cardiovascular pathologies š«Featuring Dr. Salvatore Santamaria and PhD students Tina Burkhard & Alex Minns
@uniofsurrey.bsky.social
š Nov 25 | ā° 1 PM UK š Register:
forms.gle/EY6aiWgsS3Rb...
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#aECM
Cub starts next week Nov 18 with talks on patterning the Drosophila lens, mouse tectorial membrane, and C.elegans cuticle furrows. You can still sign up for access using the link below.
add a skeleton here at some point
about 1 month ago
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Jenna Norton
about 1 month ago
Trumpās HHS put me on ānon-disciplinaryā admin leave today. This was retaliation for speaking up. Moves like this are designed to silence us. Letās not let.
www.tiktok.com/t/ZP8Dteoop/
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I guess I am hitting a nerve, because they just put me on admin leave.
TikTok video by Jenna
https://www.tiktok.com/t/ZP8Dteoop/
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May-lee Chai (she/her)
about 1 month ago
Meanwhile, ādid women ruin the workplace?ā
add a skeleton here at some point
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Needhi Bhalla š š½
about 1 month ago
āWhat these pundits are nudging us to do, ever so politely, is accept that women, in the main, are accustomed to being a little degraded, a little underpaid and ignored and dampened in their ambitions, in ways that men are not and never will beā¦What a gift it isā¦to have no choice in the matter.ā š„š„š„
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Meera Sundaram
Action Together New Jersey
about 2 months ago
#Spokane
#WA
Hunger is no Game
#VisibilityBrigade
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Meera Sundaram
Daniel Asarnow
about 2 months ago
An obituary any scientist would be proud of imo
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Meera Sundaram
Genetics Society of America
about 2 months ago
Weāre excited to expand our partnership with
@reviewcommons.org
in a new collaborative model reshaping scientific publishing to streamline peer review, reduce redundancy, and improve the author and reviewer experience. Read more:
buff.ly/h6SfMXF
And meet our Editorial Board! š
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Meera Sundaram
Mark A. Hanson
about 2 months ago
Just tried q.e.d. by
@odedrechavi.bsky.social
et al. with a few papers including by myself & others where I knew a claim within was flawed based on a misunderstanding of the signal. 1) it was impressive. I see what the hype is about. 2) it hallucinated.
www.qedscience.com
Overly long
#SciPubš§µ
1/n
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q.e.d Science
Critical Thinking AI for constructive criticism and science evaluation
https://www.qedscience.com/
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Meera Sundaram
Nature
about 2 months ago
Funders must recognise that great discoveries often come from studies that seeks to advance knowledge for its own sake
go.nature.com/3X5lbUg
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From MRI to Ozempic: breakthroughs that show why fundamental research must be protected
Nature - In these financially straitened times, funders must recognize that great discoveries often arise from work that was looking for something completely different.
https://go.nature.com/3X5lbUg
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Oof, Richard Scarry was a formative part of my youth and this is brutal. There is an election on Tuesday Nov 4. Vote to change this.
about 2 months ago
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Meera Sundaram
Cells & Development
about 2 months ago
From the lab of Maxwell Heiman discussing the interesting topic of apical ECM and the function of sensing organs and how these ECM proteins can both mechanically and biochemically modulate the organ's functions.
doi.org/10.1016/j.cd...
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Meera Sundaram
Cells & Development
about 2 months ago
The ECM is no longer in the back seat when it comes to development. Check out our special issue "Dynamics of the extracellular matrix in development, cell physiology and disease" with 8 selected articles to learn more: A š§µ
www.sciencedirect.com/special-issu...
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Cells & Development | Dynamics of the extracellular matrix in development, cell physiology and disease. | ScienceDirect.com by Elsevier
Extracellular matrices (ECMs) are everywhere in our bodyā from the sheet-like basement membranes that line epithelia and other tissues - to the loose stromal arrays of mesenchyme - to the rigid struct...
https://www.sciencedirect.com/special-issue/1057HJ3N6V3
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Meera Sundaram
Bucks County Beacon
about 2 months ago
A Rutgers University report released Monday reveals that corporate investors are gobbling up about 25% of all residential units in predominantly Black and Hispanic neighborhoods in Philadelphia, raising concerns about increased evictions, higher rents, and reduced homeownership.
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Corporate Investors Are Gobbling Up Philadelphiaās Single-Family Homes at an Unprecedented Rate, New Report Shows - Bucks County Beacon
The Rutgers University report released Monday reveals that about 25% of all residential units are purchased as nameless, faceless individuals as investors in LLCs.
https://buckscountybeacon.com/2025/10/corporate-investors-are-gobbling-up-philadelphias-single-family-homes-at-an-unprecedented-rate-new-report-shows/
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eric lai
about 2 months ago
šŖ° folks! Despite Harvard lawsuit outcome, FlyBase NIH grant was not released. FlyBase now runs on the public, like NPR, PBS etc. If we don't step up, it can go away! Donations site on
flybase.org
homepage. Note: it links to IU stock center, but its for FlyBase, see instructions. pls give+share! 2/2
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FlyBase Homepage
FlyBase: a database for drosophila genetics and molecular biology
https://flybase.org/
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Beware
#Philly
bike commuters: Problems on the Schuylkill river trail
www.phillyvoice.com/schuylkill-r...
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A 10-foot long, 8-foot deep sinkhole has caused part of the Schuylkill River Trail to temporarily close
Repairs on the section between Race Street and JFK Boulevard could take months after a large crater formed under the asphalt.
https://www.phillyvoice.com/schuylkill-river-trail-closed-sinkhole-repairs/?mc_cid=6e5d63b768&mc_eid=df0de6fd0b
2 months ago
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Joshua Weitz
2 months ago
Abandoning Merit for Compliance: Unpacking The Compact for Higher Education
substack.com/@joshuasweit...
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Abandoning Merit for Compliance: Unpacking The Compact for Higher Education
How the Dept. of Educationās proposed āCompactā for higher education would undermine merit-based review in exchange for fealty.
https://substack.com/@joshuasweitz/note/p-176800037?utm_source=notes-share-action&r=fjyhw
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Meera Sundaram
David Ho
2 months ago
We were all relieved that this didnāt happen on 9/11.
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Meera Sundaram
jon ben-menachem
2 months ago
Wow. Harvard nuking its PhD programs - Science PhD admissions reduced by more than 75% - Arts & Humanities reduced by about 60% - Social Sciences by 50ā70% - History by 60% - Biology by 75% - The German department will lose all PhD seats - Sociology from six PhD students to zero
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Harvard FAS Cuts Ph.D. Seats By More Than Half Across Next Two Admissions Cycles | News | The Harvard Crimson
The Faculty of Arts and Sciences slashed the number of Ph.D. student admissions slots for the Science division by more than 75 percent and for the Arts & Humanities division by about 60 percent for th...
https://www.thecrimson.com/article/2025/10/21/fas-phd-admissions-cuts/
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Grosshans Lab
2 months ago
And the next one:
dx.doi.org/10.1038/s44318-025-00585-z
. Super-fun collaboration with
@partchlab.bsky.social
&
@gotworms.bsky.social
to find similarities between developmental and circadian clocks ā supported by
@fmiscience.bsky.social
Facilities and, financially,
@snsf.ch
and
@erc.europa.eu
. 1/n
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Latin American worm meeting in beautiful Merida Mexico, February 24-28, 2026. Abstract deadline is October 31.
meetings.embo.org/event/26-worm
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š. š¦šš¦šØš¢šÆš“ Biology
This EMBO Workshop on C. elegans Biology is the IV Latin American Worm Meeting. It will convene in Merida, Mexico. The overall mission of this meeting is to create an inclusive environment that proā¦
http://meetings.embo.org/event/26-worm
2 months ago
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Bucks County Beacon
2 months ago
Photo Essay: Millions of Americans Join No Kings Demonstrations Across the County to Protest Trump | āBig rallies like this give confidence to people who have been sitting on the sidelines but are ready to speak up,ā
@chrismurphyct.bsky.social
told
@apnews.com
. MORE PHOTOS:
bit.ly/475cEoQ
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Bucks County Beacon
2 months ago
Photo Essay: Thousands of Democracy Defenders Protest Trump at
#NoKings
Rallies Throughout Bucks County | Doylestown, Morrisville, Perkasie and New Hope were among the locations where local residents protested Saturday because they love their country.
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Photo Essay: Thousands of Democracy Defenders Protest Trump at 'No Kings' Rallies Throughout Bucks County - Bucks County Beacon
Doylestown, Morrisville, Perkasie and New Hope were among the locations where local residents protested Saturday because they love their country.
https://buckscountybeacon.com/2025/10/photo-essay-thousands-of-democracy-defenders-protest-trump-at-no-kings-rallies-throughout-bucks-county/
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Minor Spear Carrier
2 months ago
PHILLY I stepped out to walk across Philly last night and get a sense of things. City Hall always captures me here, Philadelphia has maintained its European layout and much of its early architecture.
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Buckās county PA
#nokings
2 months ago
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Meera Sundaram
Grosshans Lab
2 months ago
Watch Lucas' amazing artistic/musical rendition of C. elegans larval development and our work on developmental timing and molting here
youtu.be/-hGHYRvw87w
and read on his inspiration and challenges below
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