Beautiful work that used C. elegans and mouse models, cell lines and human patient samples to address a complex question in aging research, which spans biochemistry, cell biology and organismal physiology. onlinelibrary.wiley.com/doi/10.1111/...

Efficient pheromone navigation via antagonistic detectors in Caenorhabditis elegans male www.nature.com/articles/s41...

Glycolytic Specialization Shapes Neuronal Physiology and Function in vivo https://www.biorxiv.org/content/10.64898/2026.02.17.706437v1

The mitochondrial chaperone HSPD1 folds MTHFD2 independently of its co-chaperone HSPE1 https://www.biorxiv.org/content/10.64898/2026.02.16.706072v1

Caenorhabditis elegans avoids Todstoff, a novel nociceptive necrotaxis cue https://www.biorxiv.org/content/10.64898/2026.02.06.704436v1

Exposure to deceased remains of conspecifics extends the lifespan of young and aged C. elegans via distinct pathways https://www.biorxiv.org/content/10.64898/2026.02.08.704602v1

CUT homeobox factors modulate chromatin accessibility in neurons https://www.biorxiv.org/content/10.64898/2026.02.10.705137v1

Molecular insights into diverse heat hormesis regimens in Caenorhabditis elegans academic.oup.com/genetics/adv...

Mild Mitochondrial Impairment Activates Overlapping Longevity Pathways Converging on the Flavin-Containing Monooxygenase FMO-2 https://www.biorxiv.org/content/10.64898/2026.02.10.705198v1

ER remodelling is a feature of ageing and depends on ER-phagy www.nature.com/articles/s41...

Distinct Molecular Mechanisms Regulate Feeding State-Dependent CO2 Chemotaxis Plasticity During Different Life Stages in Caenorhabditis elegans https://www.biorxiv.org/content/10.64898/2026.02.06.704338v1

A pilot study for whole proteome tagging in C. elegans https://www.biorxiv.org/content/10.64898/2026.02.09.704846v1

Epitope-based labeling for improved live-imaging of endogenous proteins in C. elegans https://www.biorxiv.org/content/10.64898/2026.02.05.703904v1

Cell-specific roles for the conserved Galpha chaperone RIC-8 in cilia biology https://www.biorxiv.org/content/10.64898/2026.02.07.704597v1

Improved Dye-Filling Protocol for Multiple Nematode Species www.micropublication.org/journals/bio...

I've always been a fan of what the Allen Institute is doing. New in Nature: OpenScholar, an 8B RAG model for scientific literature, outperforms GPT-4o by 6% on correctness. Experts preferred its answers over human-written ones 51%-70 of the time. www.nature.com/articles/s41... 1/3 🧵

The good folks over at Nature asked me about my thoughts on open-source AI tools like OpenScholar. You can read them in the article below: Thanks @LizzieGibney for the opportunity to share my thoughts. www.nature.com/articles/d4...

Our new work shows that live E. faecium reduces motor neuron degeneration and improves locomotion in a C. elegans ALS model. Protective effects depend on the induction of cytochrome P450 genes regulated by the intestinal nuclear hormone receptor NHR-86: journals.plos.org/plosbiology/...

Potential nematicides identified through targeted in vivo screening of a 5-HT-gated chloride channel, MOD-1 https://www.biorxiv.org/content/10.64898/2026.01.25.701312v1

A genetically encoded ionic-stress sensor reveals protons as a sleep driver https://www.biorxiv.org/content/10.64898/2026.01.27.702131v1

ATG-18 drives longevity in an HLH-30-dependent manner https://www.biorxiv.org/content/10.64898/2026.01.27.701268v1

A new set of combinatorial dimeric codes for nuclear hormone receptor–target gene specificity academic.oup.com/nar/article/...

The time of day for cancer immunotherapy is associated with major outcomes. Early is better. Results from a randomized trial of lung cancer, backs up the importance of our circadian rhythm and immune system www.nature.com/articles/s41...

RiboTRAP-seq identifies spatially distinct functions for the anterior and posterior intestine in immune and metabolic regulation in C. elegans elifesciences.org/reviewed-pre...

Our first 2026 paper is out @currentbiology.bsky.social! 👏 to @nathancsharris.bsky.social (now Asst Prof, GA State) and PD Priya Dutta. Here we show how transcriptional and trafficking pathways coordinate thermoreceptor levels to precisely modulate response plasticity www.cell.com/current-biol...

🆕 @science.org Revising the heritability of lifespan, from 25% to ~50%, by correcting for extrinsic factors science.org/doi/10.1126/...

Thanks! We were really happy with how it turned out! I got a lot of emails asking for advice about the AID system and it felt like this primer was lacking. It was great to work with Dave, Ann, and Aric and I love the idea of the curated strain collections!

The CGC has added some cool functionality to improve the searchability of the site to help find appropriate strains for your research. We are working to create a consistent nomenclature. More collections to come in the future. Folks can ask questions on Worm Slack, the Alliance forum, or here! (2)

Excited to see this out in the world. The CGC is launching a curated strains collection, the first being protein degradation systems and this is a pilot primer to pair with it authored by myself, Dave Reiner, Ann Rougvie, and Aric Daul. We review the state of the field and provide use guidance (1)

The Caenorhabditis Genetics Center Curated Special Collections: a guide to protein degradation systems academic.oup.com/genetics/adv...

IGF-like growth factors that couple food sensing to developmental decisions employ different release mechanisms in a single pair of C. elegans chemosensory neurons https://www.biorxiv.org/content/10.64898/2026.01.23.701173v1

We are thrilled to announce Francis S. Collins, former director of the NIH, as the 2026 NAS Public Welfare Medalist for his pioneering research in human genetics and critical contributions to public welfare as the leader of the Human Genome Project! www.nasonline.org/news/francis... #NASaward

The C. elegans nervous system reads the internal state of the hydrogen peroxide-detoxification machinery to trigger escape from this common reactive chemical www.biorxiv.org/content/10.6...

Bright calcium-modulated bioluminescent indicators for activity imaging and red photon-assisted synaptic transmission https://www.biorxiv.org/content/10.64898/2026.01.20.700092v1

A Course-Undergraduate Research Experience (CURE) to explore the effect of structural variants on gene expression in C. elegans balancers https://www.biorxiv.org/content/10.64898/2026.01.21.700799v1

MYRF-1/LIN-42 timing complex controls temporal patterning! www.biorxiv.org/content/10.6...

The latest work from the Hammell lab is out! Super-convergence of all the projects in our lab with some excellent collaborations with the Ercan (NYU) and the Joshua-Tor (CSHL) labs! Bluesky-torial to come! www.biorxiv.org/content/10.6...

Silencing lipid catabolism determines longevity in response to fasting www.nature.com/articles/s41...

Nature Aging @nataging.nature.com turns 5 and asked ~50 researchers to reflect on the field. I am honored to contribute alongside colleagues whose work has shaped how I think about #aging science. Past, present and future perspectives on the science of aging www.nature.com/articles/s43...

Detecting correlations, generating hypotheses, and avoiding pitfalls in the analysis of timeseries in developmental biology www.sciencedirect.com/science/arti...

Expanding the Genetic Code of an Animal with Two Non-Canonical Amino Acids https://www.biorxiv.org/content/10.64898/2026.01.20.700547v1

Less is more. This aphorism is constantly on my mind. The scientific publication system is under tremendous strain, the last thing it needs is a massive dump of LLM generated/aided papers. If you love science, then show it some love. www.nature.com/articles/d41...

Root-knot nematode Meloidogyne incognita uses secondary-metabolite-mediated soil microbiome shifts to locate host plants www.nature.com/articles/s41...

TAG-IN, a swappable strategy for endogenous gene tagging in Caenorhabditis elegans using cassette exchange https://www.biorxiv.org/content/10.64898/2026.01.16.700006v1

She uses the bristled end of a deck brush on her back and hindquarters, using repeated place-and-pull motions. For more sensitive areas such as the belly flap, udder, and anal region, she switches to the stick end, using careful, repeated poke-and-lift movements. See video link: youtu.be/bAk4PFEuWKQ

Our new paper (with @biotay.bsky.social) is out and on the cover story of @currentbiology.bsky.social !!!! Veronika, a Carinthian mountain cow flexibly uses a “multi-purpose tool” to scratch herself. A video and more information will follow in the comments. www.cell.com/current-biol...

LONP-1 deficiency causes dysregulated protein synthesis within mitochondria that is restored by mitoribosomal mutations https://www.biorxiv.org/content/10.64898/2026.01.14.699555v1

Pre-dauer starvation rapidly and reversibly reduces niche proliferative signaling to the C. elegans germ line journals.biologists.com/dev/article/...

Development's team of Academic Editors challenge the perception that Development is ‘too hard to publish in’ by reviewing journal metrics, discussing the journal's review process and clarifying the support they provide to authors. journals.biologists.com/dev/article/...

Your gut has a sex, and it matters! 🔥 In females, the ovary sends a relaxin hormone signal to enteric neurons, switching on gut enlargement and increased feeding after mating. So excited my postdoc work is finally out as a preprint 🥳 www.biorxiv.org/content/10.6...