Bioengineered algal lipids enriched in structured medium- and long-chain triacylglycerols, linoleate, and sn-2 palmitate for human milk fat substitutes https://www.biorxiv.org/content/10.64898/2026.05.15.725531v1

Genetic code expansion enables programmable covalent protein design https://www.biorxiv.org/content/10.64898/2026.05.15.725538v1

Heterologous expression of lyngbyatoxin biosynthetic genes in Aspergillus oryzae reveals transcriptional barriers but enables LtxC-mediated biotransformation https://www.biorxiv.org/content/10.64898/2026.05.15.725566v1

Run or glide: muscles are indifferent while the tendon takes the strain https://www.biorxiv.org/content/10.64898/2026.05.15.725315v1

HaloTag Ligand and HaloTag Protein engineering for a binary fluorescent turn-on probe https://www.biorxiv.org/content/10.64898/2026.05.15.724826v1

Bacteriophage P22 virus-like particles as nanoscale protein scaffolds for plant synthetic biology https://www.biorxiv.org/content/10.64898/2026.05.14.725278v1

Covalent tumor anchoring spatially orchestrates antitumor immunity https://www.biorxiv.org/content/10.64898/2026.05.13.724746v1

Engineering high-titer lentiviral vectors for robust expression of RNA-based gene circuits https://www.biorxiv.org/content/10.64898/2026.05.12.724401v1

Engineering orthogonal quorum sensing circuits using LuxR-type systems in yeast consortia https://www.biorxiv.org/content/10.64898/2026.05.13.724834v1

Post-translational modification fidelity of recombinant human lactopontin expressed in Kluyveromyces lactis https://www.biorxiv.org/content/10.64898/2026.05.12.724256v1

Programmable synthetic cytokine receptors polarize macrophages to user-defined functional states https://www.biorxiv.org/content/10.64898/2026.05.12.724672v1

Engineered gut symbionts mediate cross-phylum antagonism to suppress uropathogenic Escherichia coli colonization https://www.biorxiv.org/content/10.64898/2026.05.11.724322v1

DNA Staples: An oligonucleotide library for data storage and computing https://www.biorxiv.org/content/10.64898/2026.05.11.724305v1

A two-step selection method for in vitro evolution of translational proteins https://www.biorxiv.org/content/10.64898/2026.05.09.724044v1

Complete biosynthesis of penicillin G in Nicotiana benthamiana https://www.biorxiv.org/content/10.64898/2026.05.08.723852v1

Phage-assisted continuous evolution of enzymes for noncanonical tyrosine biosynthesis https://www.biorxiv.org/content/10.64898/2026.05.08.723366v1

Noise analysis of derivative-action biomolecular topologies https://www.biorxiv.org/content/10.64898/2026.05.06.723344v1

FASTOP - Fast editing toolkit for top expression sites in yeast https://www.biorxiv.org/content/10.64898/2026.05.07.723299v1

Automated Synthetic Cell-based Screening for Designed Proteins with Emergent Functions https://www.biorxiv.org/content/10.64898/2026.05.07.723257v1

Towards autonomous biology: Compiler-Verified Protocols as a Foundation for Real World AI Execution https://www.biorxiv.org/content/10.64898/2026.05.05.720956v1

Systematic mapping of chimera-permissive sites by CRISPR-guided PAM scanning https://www.biorxiv.org/content/10.64898/2026.05.06.723292v1

NI2+ AND ZN2+-BINDING DNA MOTIFS REVEALED IN DNA APTAMERS TO AFRICAN SWINE FEVER VIRUS https://www.biorxiv.org/content/10.64898/2026.05.05.722837v1

The genetically-encoded amino acids distribute non-randomly within a functionally-relevant chemical space https://www.biorxiv.org/content/10.64898/2026.05.06.723277v1

Interactomics-driven discovery of alkaloid biosynthetic pathways in kratom https://www.biorxiv.org/content/10.64898/2026.05.01.722234v1

Enhanced Bacillus subtilis natural competence enables multiplexed genome and spore engineering https://www.biorxiv.org/content/10.64898/2026.05.01.722266v1

Genetic Programming of Bacterial Microcompartments: Operon Order as a Tool for Nanoscale Morphogenesis https://www.biorxiv.org/content/10.64898/2026.05.01.722140v1

Learning the structural diversity in random protein sequence space https://www.biorxiv.org/content/10.64898/2026.04.30.722084v1

Wnt signaling and tissue tension reconstitute planar cell polarity in vitro https://www.biorxiv.org/content/10.64898/2026.05.01.722304v1

Functional Profiling of Thousands of Sequence-Diverse Protease Homologs with GROQ-seq https://www.biorxiv.org/content/10.64898/2026.04.30.721934v1

In vitro evolution of DNA operators enables multivalency protein-DNA interactions: towards programmable transcription factor regulation https://www.biorxiv.org/content/10.64898/2026.05.02.721436v1

A droplet microfluidic-based platform for enhanced DNA delivery in non-model organisms https://www.biorxiv.org/content/10.64898/2026.04.30.721591v1

A VERSATILE LIBRARY OF TETRACYCLINE-INDUCIBLE AND REPRESSIBLE VECTORS FOR FINE-TUNED GENE EXPRESSION https://www.biorxiv.org/content/10.64898/2026.04.30.721401v1

Optimizing Lentiviral Vector-Based Delivery of SCN1A transgenes to Mammalian Cells https://www.biorxiv.org/content/10.64898/2026.05.01.722074v1

Mitigating Family Effects in RNA Secondary-Structure Prediction with Latent-Space Continual Learning https://www.biorxiv.org/content/10.64898/2026.04.29.721709v1

Bridge recombinase enables versatile rewriting of bacterial genomes https://www.biorxiv.org/content/10.64898/2026.04.29.721476v1

Generative design of sequence specific DNA binding proteins https://www.biorxiv.org/content/10.64898/2026.04.27.720408v1

Spatial organization of enzymes and cofactors in synthetic membrane-associated condensates (sMACs) https://www.biorxiv.org/content/10.64898/2026.04.24.720695v1

PhAGE Enables One-Step Genome Integration of Large DNA Fragments in Escherichia coli https://www.biorxiv.org/content/10.64898/2026.04.23.720475v1

A liquid handling platform for standardised quantification of cell-free enzymatic activity encoded by antimicrobial resistance genes https://www.biorxiv.org/content/10.64898/2026.04.23.720151v1

yakRNA Design: A semantic multimodal RNA composer https://www.biorxiv.org/content/10.64898/2026.04.22.720245v1

Unsupervised protein language models learn patterns of enzyme function https://www.biorxiv.org/content/10.64898/2026.04.23.720319v1

A Proteome-Calibrated Mechanistic Digital Twin of the Glioblastoma Astrocyte Derived from Patient Multi-Omic Data https://www.biorxiv.org/content/10.64898/2026.04.23.719998v1

Delineating the Transcriptional and Phenotypic Impact from Biotherapeutic Glycoengineering https://www.biorxiv.org/content/10.64898/2026.04.21.719832v1

Rational engineering enhances the signal and modularity of an RNA barcoding technology to track gene transfer in microbiomes https://www.biorxiv.org/content/10.64898/2026.04.20.719664v1

A novel polymerase III promoter for gene editing in the agricultural pest Ceratitis capitata https://www.biorxiv.org/content/10.64898/2026.04.21.719894v1

Selective Hydrolytic Defluorination of Branched Perfluorooctanoic Acid Isomers by a Haloacid Dehalogenase https://www.biorxiv.org/content/10.64898/2026.04.19.719434v1

A trainable language model for modulating translation rates in non-model organisms by generating upstream untranslated region sequence libraries https://www.biorxiv.org/content/10.64898/2026.04.18.719341v1

Elucidating the Bell-Shaped Dependence of Protein Translation Activity on EF-Tu Concentration in a Reconstituted Cell-Free System Using a Mechanistic Model https://www.biorxiv.org/content/10.64898/2026.04.17.719328v1

Conjugation-based genome engineering enables rapid prototyping and bioproduction in non-model bacteria https://www.biorxiv.org/content/10.64898/2026.04.17.717921v1

The Synthetic Epitope Atlas: High-Throughput Design and Validation of De Novo Antibody-Antigen Complexes https://www.biorxiv.org/content/10.64898/2026.04.17.719295v1