bioRxiv Synthetic Biology
@biorxiv-synthbio.bsky.social
📤 1587
📥 0
📝 1317
Bioengineered algal lipids enriched in structured medium- and long-chain triacylglycerols, linoleate, and sn-2 palmitate for human milk fat substitutes
https://www.biorxiv.org/content/10.64898/2026.05.15.725531v1
about 14 hours ago
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Genetic code expansion enables programmable covalent protein design
https://www.biorxiv.org/content/10.64898/2026.05.15.725538v1
about 15 hours ago
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2
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Heterologous expression of lyngbyatoxin biosynthetic genes in Aspergillus oryzae reveals transcriptional barriers but enables LtxC-mediated biotransformation
https://www.biorxiv.org/content/10.64898/2026.05.15.725566v1
about 15 hours ago
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Run or glide: muscles are indifferent while the tendon takes the strain
https://www.biorxiv.org/content/10.64898/2026.05.15.725315v1
1 day ago
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HaloTag Ligand and HaloTag Protein engineering for a binary fluorescent turn-on probe
https://www.biorxiv.org/content/10.64898/2026.05.15.724826v1
1 day ago
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1
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Bacteriophage P22 virus-like particles as nanoscale protein scaffolds for plant synthetic biology
https://www.biorxiv.org/content/10.64898/2026.05.14.725278v1
1 day ago
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Covalent tumor anchoring spatially orchestrates antitumor immunity
https://www.biorxiv.org/content/10.64898/2026.05.13.724746v1
3 days ago
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Engineering high-titer lentiviral vectors for robust expression of RNA-based gene circuits
https://www.biorxiv.org/content/10.64898/2026.05.12.724401v1
3 days ago
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4
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Engineering orthogonal quorum sensing circuits using LuxR-type systems in yeast consortia
https://www.biorxiv.org/content/10.64898/2026.05.13.724834v1
4 days ago
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Post-translational modification fidelity of recombinant human lactopontin expressed in Kluyveromyces lactis
https://www.biorxiv.org/content/10.64898/2026.05.12.724256v1
5 days ago
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Programmable synthetic cytokine receptors polarize macrophages to user-defined functional states
https://www.biorxiv.org/content/10.64898/2026.05.12.724672v1
5 days ago
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1
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Engineered gut symbionts mediate cross-phylum antagonism to suppress uropathogenic Escherichia coli colonization
https://www.biorxiv.org/content/10.64898/2026.05.11.724322v1
5 days ago
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DNA Staples: An oligonucleotide library for data storage and computing
https://www.biorxiv.org/content/10.64898/2026.05.11.724305v1
5 days ago
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A two-step selection method for in vitro evolution of translational proteins
https://www.biorxiv.org/content/10.64898/2026.05.09.724044v1
7 days ago
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2
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Complete biosynthesis of penicillin G in Nicotiana benthamiana
https://www.biorxiv.org/content/10.64898/2026.05.08.723852v1
7 days ago
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1
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Phage-assisted continuous evolution of enzymes for noncanonical tyrosine biosynthesis
https://www.biorxiv.org/content/10.64898/2026.05.08.723366v1
8 days ago
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4
1
Noise analysis of derivative-action biomolecular topologies
https://www.biorxiv.org/content/10.64898/2026.05.06.723344v1
9 days ago
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FASTOP - Fast editing toolkit for top expression sites in yeast
https://www.biorxiv.org/content/10.64898/2026.05.07.723299v1
9 days ago
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Automated Synthetic Cell-based Screening for Designed Proteins with Emergent Functions
https://www.biorxiv.org/content/10.64898/2026.05.07.723257v1
9 days ago
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Towards autonomous biology: Compiler-Verified Protocols as a Foundation for Real World AI Execution
https://www.biorxiv.org/content/10.64898/2026.05.05.720956v1
10 days ago
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Systematic mapping of chimera-permissive sites by CRISPR-guided PAM scanning
https://www.biorxiv.org/content/10.64898/2026.05.06.723292v1
10 days ago
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NI2+ AND ZN2+-BINDING DNA MOTIFS REVEALED IN DNA APTAMERS TO AFRICAN SWINE FEVER VIRUS
https://www.biorxiv.org/content/10.64898/2026.05.05.722837v1
10 days ago
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The genetically-encoded amino acids distribute non-randomly within a functionally-relevant chemical space
https://www.biorxiv.org/content/10.64898/2026.05.06.723277v1
10 days ago
1
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Interactomics-driven discovery of alkaloid biosynthetic pathways in kratom
https://www.biorxiv.org/content/10.64898/2026.05.01.722234v1
12 days ago
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Enhanced Bacillus subtilis natural competence enables multiplexed genome and spore engineering
https://www.biorxiv.org/content/10.64898/2026.05.01.722266v1
12 days ago
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1
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Genetic Programming of Bacterial Microcompartments: Operon Order as a Tool for Nanoscale Morphogenesis
https://www.biorxiv.org/content/10.64898/2026.05.01.722140v1
12 days ago
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1
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Learning the structural diversity in random protein sequence space
https://www.biorxiv.org/content/10.64898/2026.04.30.722084v1
12 days ago
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Wnt signaling and tissue tension reconstitute planar cell polarity in vitro
https://www.biorxiv.org/content/10.64898/2026.05.01.722304v1
12 days ago
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Functional Profiling of Thousands of Sequence-Diverse Protease Homologs with GROQ-seq
https://www.biorxiv.org/content/10.64898/2026.04.30.721934v1
12 days ago
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1
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In vitro evolution of DNA operators enables multivalency protein-DNA interactions: towards programmable transcription factor regulation
https://www.biorxiv.org/content/10.64898/2026.05.02.721436v1
13 days ago
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2
2
A droplet microfluidic-based platform for enhanced DNA delivery in non-model organisms
https://www.biorxiv.org/content/10.64898/2026.04.30.721591v1
14 days ago
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A VERSATILE LIBRARY OF TETRACYCLINE-INDUCIBLE AND REPRESSIBLE VECTORS FOR FINE-TUNED GENE EXPRESSION
https://www.biorxiv.org/content/10.64898/2026.04.30.721401v1
16 days ago
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1
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Optimizing Lentiviral Vector-Based Delivery of SCN1A transgenes to Mammalian Cells
https://www.biorxiv.org/content/10.64898/2026.05.01.722074v1
16 days ago
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Mitigating Family Effects in RNA Secondary-Structure Prediction with Latent-Space Continual Learning
https://www.biorxiv.org/content/10.64898/2026.04.29.721709v1
16 days ago
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Bridge recombinase enables versatile rewriting of bacterial genomes
https://www.biorxiv.org/content/10.64898/2026.04.29.721476v1
18 days ago
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28
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Generative design of sequence specific DNA binding proteins
https://www.biorxiv.org/content/10.64898/2026.04.27.720408v1
20 days ago
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4
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Spatial organization of enzymes and cofactors in synthetic membrane-associated condensates (sMACs)
https://www.biorxiv.org/content/10.64898/2026.04.24.720695v1
20 days ago
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2
2
PhAGE Enables One-Step Genome Integration of Large DNA Fragments in Escherichia coli
https://www.biorxiv.org/content/10.64898/2026.04.23.720475v1
23 days ago
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1
1
A liquid handling platform for standardised quantification of cell-free enzymatic activity encoded by antimicrobial resistance genes
https://www.biorxiv.org/content/10.64898/2026.04.23.720151v1
24 days ago
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yakRNA Design: A semantic multimodal RNA composer
https://www.biorxiv.org/content/10.64898/2026.04.22.720245v1
24 days ago
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Unsupervised protein language models learn patterns of enzyme function
https://www.biorxiv.org/content/10.64898/2026.04.23.720319v1
24 days ago
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1
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A Proteome-Calibrated Mechanistic Digital Twin of the Glioblastoma Astrocyte Derived from Patient Multi-Omic Data
https://www.biorxiv.org/content/10.64898/2026.04.23.719998v1
24 days ago
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Delineating the Transcriptional and Phenotypic Impact from Biotherapeutic Glycoengineering
https://www.biorxiv.org/content/10.64898/2026.04.21.719832v1
25 days ago
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Rational engineering enhances the signal and modularity of an RNA barcoding technology to track gene transfer in microbiomes
https://www.biorxiv.org/content/10.64898/2026.04.20.719664v1
26 days ago
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A novel polymerase III promoter for gene editing in the agricultural pest Ceratitis capitata
https://www.biorxiv.org/content/10.64898/2026.04.21.719894v1
26 days ago
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1
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Selective Hydrolytic Defluorination of Branched Perfluorooctanoic Acid Isomers by a Haloacid Dehalogenase
https://www.biorxiv.org/content/10.64898/2026.04.19.719434v1
27 days ago
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A trainable language model for modulating translation rates in non-model organisms by generating upstream untranslated region sequence libraries
https://www.biorxiv.org/content/10.64898/2026.04.18.719341v1
27 days ago
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1
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Elucidating the Bell-Shaped Dependence of Protein Translation Activity on EF-Tu Concentration in a Reconstituted Cell-Free System Using a Mechanistic Model
https://www.biorxiv.org/content/10.64898/2026.04.17.719328v1
27 days ago
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Conjugation-based genome engineering enables rapid prototyping and bioproduction in non-model bacteria
https://www.biorxiv.org/content/10.64898/2026.04.17.717921v1
29 days ago
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The Synthetic Epitope Atlas: High-Throughput Design and Validation of De Novo Antibody-Antigen Complexes
https://www.biorxiv.org/content/10.64898/2026.04.17.719295v1
29 days ago
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1
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