A Computational Framework for Domain Insertion into Type IV Pili for Bacterial Display and Living Material Assembly https://www.biorxiv.org/content/10.64898/2026.06.09.731259v1

A Low-Cost, High-Throughput Design-Build-Test Pipeline for Engineering Genetic Systems: Stress Testing with Complex Structural Proteins https://www.biorxiv.org/content/10.64898/2026.06.08.729977v1

TaxoFormer: Hierarchical Transformer for Predicting the Full Taxonomic Lineage of Protein Sequences https://www.biorxiv.org/content/10.64898/2026.06.06.730618v1

Complex-phase stochastic modeling of mitochondrial heteroplasmy https://www.biorxiv.org/content/10.64898/2026.06.07.730672v1

A Drug-Target Specificity Foundation Model for Off-target Prediction, Repurposing, and Generative Design https://www.biorxiv.org/content/10.64898/2026.06.08.730844v1

Inosine incorporation in DNA nanostructures and 3D DNA crystals https://www.biorxiv.org/content/10.64898/2026.06.06.730639v1

Catalytic Bacterial Nanocellulose Composite That Captures and Degrades PET Microplastics https://www.biorxiv.org/content/10.64898/2026.06.05.730390v1

MicroGrowAgents: An Agentic AI System for Microbial Cultivation Engineering https://www.biorxiv.org/content/10.64898/2026.06.04.729985v1

Split-Indigoidine synthetase as optical reporter for benchmarking protein-protein interactions https://www.biorxiv.org/content/10.64898/2026.06.03.729908v1

Vibe Coding Specificity Foundation Models https://www.biorxiv.org/content/10.64898/2026.06.04.730134v1

Enhancing Reverse Methanogenesis Using RNA-Guided Silencing https://www.biorxiv.org/content/10.64898/2026.06.03.729817v1

Integrated valorization of glycerol and PET into lipids and PHAs using an engineered Yarrowia lipolytica strain and a Pseudomonas-Comamonas consortium https://www.biorxiv.org/content/10.64898/2026.06.02.729029v1

Developing engineering strategies to enhance the genetic stability of fatty alcohol-producing strains for production scale-up https://www.biorxiv.org/content/10.64898/2026.06.01.728301v1

CRISPRi-assisted E. coli strains increase success rate of burdensome construct cloning https://www.biorxiv.org/content/10.64898/2026.06.02.729553v1

Dual-Chassis Strategy for Bridging Adaptive Evolution and Rational Design for Synthetic Biology https://www.biorxiv.org/content/10.64898/2026.06.02.729570v1

Characterizing Sequence-Function Relationships in Chimeric DcuS/EnvZ Histidine Kinases at Scale https://www.biorxiv.org/content/10.64898/2026.06.03.728855v1

Engineering a Novel Bacterial Encapsulin for Programmable Surface Functionalization: From Single-Target to Mosaic Nanovaccines https://www.biorxiv.org/content/10.64898/2026.06.01.729406v1

Generating E. coli 0.5 controlled by a half-sized genome https://www.biorxiv.org/content/10.64898/2026.06.01.729178v1

ProNotch converts extracellular protease activity into programmable transcriptional outputs https://www.biorxiv.org/content/10.64898/2026.06.01.728985v1

Integrated valorisation of PET and xylose using the oleaginous microorganisms Yarrowia lipolytica and Rhodococcus jostii https://www.biorxiv.org/content/10.64898/2026.05.30.728943v1

DropSynth-Gold: Golden Gate Assembly in Emulsions Extends Multiplexed Gene Libraries to Greater Lengths https://www.biorxiv.org/content/10.64898/2026.05.29.728538v1

Transcriptomic and proteomic responses to gas vesicle collapse in native and engineered bacterial systems https://www.biorxiv.org/content/10.64898/2026.05.31.729101v1

Engineering Biosensors to Enhance Monoterpene Indole Alkaloid Production in Yeast https://www.biorxiv.org/content/10.64898/2026.06.01.729246v1

Combinatorial and Inducible CRISPRa/i Enables Canalized hiPSC Forward Programming and Iterative Refinement via Single-Cell Genomics https://www.biorxiv.org/content/10.64898/2026.05.31.729073v1

Rapid Isothermal Detection of Heavy Metals via Transcription-Factor-Gated DNA Strand Synthesis https://www.biorxiv.org/content/10.64898/2026.05.29.728911v1

Ontology-driven software engineering using LLMs for knowledge graphs in engineering biology https://www.biorxiv.org/content/10.64898/2026.05.29.728869v1

Genetic code expansion enables plant-directed control of bacterial activity https://www.biorxiv.org/content/10.64898/2026.05.29.728790v1

Synthetic cell-cell adhesion provides benefits of proximity without diffusion-related costs https://www.biorxiv.org/content/10.64898/2026.05.28.728462v1

DNA condensate-based organelles for spatially regulated gene expression and protein targeting in synthetic cells https://www.biorxiv.org/content/10.64898/2026.05.27.728287v1

A multichromatic UV-RGB optogenetic toolbox for control of gene expression in Pseudomonas putida https://www.biorxiv.org/content/10.64898/2026.05.27.727800v1

Long-term stability of soil microbiome structure and function in liquid soil extracts https://www.biorxiv.org/content/10.64898/2026.05.29.728658v1

Certified Steady-State Parameter-Interval Design for Uncertain Biomolecular Models using a Global Shaving Contractor https://www.biorxiv.org/content/10.64898/2026.05.28.728397v1

Bispecific Coiled-Coil Reporters Enable Rapid, Multiplexed Detection of Mycoplasma via Toehold Switch Sensors https://www.biorxiv.org/content/10.64898/2026.05.28.728408v1

Identification of a native Type I Secretion System cargo in Zymomonas mobilis and its application for extracellular enzyme secretion https://www.biorxiv.org/content/10.64898/2026.05.28.728472v1

Paving the way for plant-based bioproduction of (Z)-13-octadecenoic moth pheromone compounds https://www.biorxiv.org/content/10.64898/2026.05.25.727624v1

Chemically tunable permeability of engineered alpha-Hemolysin in synthetic cells https://www.biorxiv.org/content/10.64898/2026.05.26.727826v1

An engineered streptavidin condensate platform for chemically inducible control of endogenous proteins in mammalian cells https://www.biorxiv.org/content/10.64898/2026.05.22.725644v1

A novel reaction-diffusion architecture for engineering self-organized patterns in mammalian cells https://www.biorxiv.org/content/10.64898/2026.05.24.727552v1

Artificial initiation codons and engineered initiator tRNAs enable N-terminal noncanonical amino acid incorporation in intact cell-free translation systems https://www.biorxiv.org/content/10.64898/2026.05.24.725928v1

Splice-Aware Optimization Prevents Pervasive Missplicing of Natural and Synthetic cDNAs https://www.biorxiv.org/content/10.64898/2026.05.25.727620v1

Coupling Mechanical Regulation with Biochemical Reaction-Diffusion Circuits Yields Robust Self-Organized Pattern Formation. https://www.biorxiv.org/content/10.64898/2026.05.23.727407v1

Programmable assembly of higher-order DNA nanostructures from microbial ssDNA staple libraries https://www.biorxiv.org/content/10.64898/2026.05.24.727530v1

Spatial Regulation of CAR Signaling Enables Logic-Gated Activity https://www.biorxiv.org/content/10.64898/2026.05.22.726983v1

Engineered microRNA feedback circuits enable tunable and autonomous control of synthetic receptor activity https://www.biorxiv.org/content/10.64898/2026.05.22.727153v1

A generalizable system for antigenic peptide targeting across HLA-I allotypes https://www.biorxiv.org/content/10.64898/2026.05.21.726655v1

High-throughput engineering of ligand-activated splicing ribozyme through domain insertion https://www.biorxiv.org/content/10.64898/2026.05.21.726912v1

An Enhanced Split Intein-Mediated Ligation (SIML) Platform for Rapid Discovery and Functional Screening of Circular Bacteriocins https://www.biorxiv.org/content/10.64898/2026.05.21.726877v1

3D bioprinting of engineered living materials in support slurries for complex free-standing structures https://www.biorxiv.org/content/10.64898/2026.05.20.726626v1

Clinical Campylobacter jejuni isolates: genomes and genetic tools https://www.biorxiv.org/content/10.64898/2026.05.21.726778v1

A Synthetic Platform for Antibody Junctional Diversification Beyond Natural Constraints https://www.biorxiv.org/content/10.64898/2026.05.21.726110v1