Cell-type specific allelic dampening of sex-linked genes in sex chromosome aneuploidy https://www.biorxiv.org/content/10.64898/2026.04.16.719032v1

Molecular basis of cooperative assembly of the Ndc80-Ska kinetochore complex on microtubules https://www.biorxiv.org/content/10.64898/2026.04.18.719381v1

High-variance phenome database reveals important roles of WD40 proteins in the plant pathogenic fungus Fusarium graminearum https://www.biorxiv.org/content/10.64898/2026.04.19.719521v1

Ratiometric Fluorescent Protein Biosensors Reveal Citrate Dynamics and Cellular Heterogeneity https://www.biorxiv.org/content/10.64898/2026.04.16.718871v1

SARS-CoV-2 spike protein-associated sialoglycoconjugates induce nanoscale filipodia to facilitate micro-size platelet clotting https://www.biorxiv.org/content/10.64898/2026.04.19.719510v1

Evaluation of deep and dynamic proteomic screening strategies at sub-50Hz scan rate and without automation. https://www.biorxiv.org/content/10.64898/2026.04.15.718630v1

The LARP1 RRM functions as a ribosome responsive regulator of TOP mRNAs https://www.biorxiv.org/content/10.64898/2026.04.18.719249v1

The vacuolar tauopathy-associated mutation D395G confers redox sensitivity to p97/VCP https://www.biorxiv.org/content/10.64898/2026.04.16.718620v1

Dissecting polycomb complexes for enhanced fetal hemoglobin production https://www.biorxiv.org/content/10.64898/2026.04.16.718974v1

PREFERENTIAL INVASION OF DIFFERENTIATED BLADDER CARCINOMA CELLS BY FLAGELLATED GROUP B2 ESCHERICHIA COLI https://www.biorxiv.org/content/10.64898/2026.04.16.718932v1

In silico structural analysis of EthA substitutions for ranking priority mutations leading to ethionamide resistance in Mycobacterium tuberculosis https://www.biorxiv.org/content/10.64898/2026.04.16.718980v1

Mosquito-directed PROTACs to block malaria transmission https://www.biorxiv.org/content/10.64898/2026.04.16.719026v1

Chromatin association promotes UBR5-mediated degradation of Rb https://www.biorxiv.org/content/10.64898/2026.04.16.719064v1

Evolution of the highest fidelity DNA replication systems https://www.biorxiv.org/content/10.64898/2026.04.16.719065v1

An integrated pipeline to count individual transcripts with single-cell resolution https://www.biorxiv.org/content/10.64898/2026.04.15.718387v1

Compartment-resolved in vivo phage display biopanning reveals constraint-driven peptide sequence landscapes https://www.biorxiv.org/content/10.64898/2026.04.16.719084v1

Detecting misfolded non-covalent lasso entanglements in protein structures, simulation trajectories, and mass spectrometry data https://www.biorxiv.org/content/10.64898/2026.04.15.718775v1

Disturbed ATP and AMPK homeostasis in an AnkF377del mouse model for craniometaphyseal dysplasia https://www.biorxiv.org/content/10.64898/2026.04.15.717889v1

Preservation of full-length transcripts at ambient temperature using ensilication https://www.biorxiv.org/content/10.64898/2026.04.13.717197v1

Distribution and p300/CBP dependency of cis-regulatory elements are encoded by unique combinations of histone lactylation and acetylation https://www.biorxiv.org/content/10.64898/2026.04.14.718598v1

HIV and Cocaine exposure promote Tau phosphorylation through RSK-1 in a GSK3β-independent manner. https://www.biorxiv.org/content/10.64898/2026.04.14.718541v1

Spatiotemporal and demographic effects on avian malaria prevalence in blue tits https://www.biorxiv.org/content/10.64898/2026.04.15.718266v1

Targeting CLK1 by CRISPR tools and pharmacological inhibition modulates the innate immune response and dengue virus replication https://www.biorxiv.org/content/10.64898/2026.04.15.718750v1

Temporal gating dictates stress-induced transcript export from the nucleus https://www.biorxiv.org/content/10.64898/2026.04.14.718555v1

The RNase and RNA binding activities of selected RNase R truncations and mutations plus a detailed step by step protocol to purify recombinant RNase R https://www.biorxiv.org/content/10.64898/2026.04.15.718802v1

Cell-autonomous restoration of splicing homeostasis and RP11 phenotype in patient-derived RPE and retinal organoids by PRPF31.AAV gene therapy https://www.biorxiv.org/content/10.64898/2026.04.14.718379v1

PERSISTENT LOW-LEVEL INFECTIONS OF ELEPHANT ENDOTHELIOTROPIC HERPESVIRUS AND ELEPHANT GAMMAHERPESVIRUSDETECTED IN SKIN NODULES AND SALIVA FROM WILD AND ZOO AFRICAN ELEPHANTS https://www.biorxiv.org/content/10.64898/2026.04.14.718412v1

Molecular mechanisms of PDCD4-mediated modulation of translation initiation and termination https://www.biorxiv.org/content/10.64898/2026.04.14.718391v1

Epigenetic changes induced by developmental PFAS exposure in zebrafish associate with behavioral alterations in unexposed offspring https://www.biorxiv.org/content/10.64898/2026.04.14.718393v1

Fruitless produces diverse neuronal sex differences by editing lineage-programmed chromatin landscapes https://www.biorxiv.org/content/10.64898/2026.04.14.718444v1

Nature's antivenom: Combinations of conserved rattlesnake serum metalloproteinase inhibitors block the lethal action of viper venoms https://www.biorxiv.org/content/10.64898/2026.04.13.718210v1

Ultra-sensitive FLORA-seq links cell-type-specific tRNAome dynamics to differentiation trajectories guiding therapeutic suppressor tRNA candidate selection https://www.biorxiv.org/content/10.64898/2026.04.14.718460v1

Identification of cellular double-stranded RNAs in mammalian embryonic stem cells https://www.biorxiv.org/content/10.64898/2026.04.13.718158v1

Rpd3L Coordinates Chromatin State and Transcription-Replication Conflict Resolution through H3K4 Methylation-Dependent and Independent Mechanisms https://www.biorxiv.org/content/10.64898/2026.04.13.718173v1

Fine-tuning m6A and METTL3 levels have profound impact on cellular proliferation and protein synthesis https://www.biorxiv.org/content/10.64898/2026.04.14.718245v1

TREX2 component PCID2 scaffolds alternative SAC3-based subcomplexes with distinct RNA processing and export function https://www.biorxiv.org/content/10.64898/2026.04.13.716336v1

FXR and BET signaling orchestrate to protect β cells https://www.biorxiv.org/content/10.64898/2026.04.10.716420v1

Optimizing data quality and completeness in visual proteomics experiments https://www.biorxiv.org/content/10.64898/2026.04.12.717927v1

Loss of host factor-mediated m6Am methylation of the viral RNA cap impairs SARS CoV-2 replication https://www.biorxiv.org/content/10.64898/2026.04.10.717462v1

Investigating dietary microRNA stability and function using a transgenic milk model with unique microRNA sequences https://www.biorxiv.org/content/10.64898/2026.04.13.718217v1

NaP-TRAP: A versatile and accessible workflow to dissect principles of translational regulation and mRNA stability https://www.biorxiv.org/content/10.64898/2026.04.12.718002v1

Long-lived yeast-derived lipids promote longevity via regional and systemic metabolic remodeling https://www.biorxiv.org/content/10.64898/2026.04.10.717033v1

Extracellular Vesicles From Metabolically Healthy Obesity Convey Distinct Molecular Signals That Initiate Endothelial Dysfunction: A Multi-Omics Study in Adults of African Ancestry https://www.biorxiv.org/content/10.64898/2026.04.09.717593v1

THE COMPARATIVE STUDY OF THE EFFECT OF LOW-INTENSITY BROADBAND AND LOW-INTENSITY PULSED ULTRASOUND ON THE AMPUTATIONAL MODEL OF WOUND https://www.biorxiv.org/content/10.64898/2026.04.09.717366v1

The lncRNA FENDRR fine-tunes FOXF1 protein levels through a negative feedback loop governing human embryonic lung fibroblast-to-myofibroblast transition https://www.biorxiv.org/content/10.64898/2026.04.10.716765v1

Multi-objective Engineering of Trimethylamine Monooxygenase for Improved Thermostability and Cofactor Use https://www.biorxiv.org/content/10.64898/2026.04.10.717641v1

Learning latent conformational landscapes encoded in cryo-EM https://www.biorxiv.org/content/10.64898/2026.04.10.717737v1

Thiol methyltransferase METTL7B coordinates lipid metabolism and promotes tumor progression in pancreatic cancer https://www.biorxiv.org/content/10.64898/2026.04.09.717095v1

Protenix-v2: Broadening the Reach of Structure Prediction and Biomolecular Design https://www.biorxiv.org/content/10.64898/2026.04.10.717613v1

"Editing the conserved IPA1-TB1 regulatory module reshapes plant architecture and enhances tillering in wheat https://www.biorxiv.org/content/10.64898/2026.04.09.717480v1