bioRxiv Molecular Biology
@biorxiv-molbio.bsky.social
📤 2086
📥 0
📝 5576
The widely used eGFP sequence produces an unintended protein product
https://www.biorxiv.org/content/10.64898/2026.06.02.729456v1
about 3 hours ago
0
0
0
Structural Dynamics of RNA Polymerase II During Nucleotide Addition Cycle
https://www.biorxiv.org/content/10.64898/2026.06.04.730248v1
about 11 hours ago
0
0
0
dCas allele sequestration (das-CRISPR): A Versatile New Method to Achieve Monoallelic Gene Editing in Mouse Embryos and in cell culture.
https://www.biorxiv.org/content/10.64898/2026.06.03.729891v1
1 day ago
0
2
0
EZH2 inactivation drives MAPK-dependent vulnerability to MEK inhibition in RAS-mutant CMML
https://www.biorxiv.org/content/10.64898/2026.06.02.729524v1
1 day ago
0
0
0
Antisense Oligonucleotides Targeting an LDLR Regulatory RNA Increase LDLR Expression and Reduce LDL-cholesterol in Vivo
https://www.biorxiv.org/content/10.64898/2026.06.02.729508v1
1 day ago
0
0
0
Modelling antibody structures at the speed of language
https://www.biorxiv.org/content/10.64898/2026.06.03.729879v1
1 day ago
0
0
0
Persistent TOP1 cleavage complexes in drug-tolerant cells drive adaptive resistance to EGFR-targeted therapies in lung cancer
https://www.biorxiv.org/content/10.64898/2026.06.02.729207v1
1 day ago
0
0
0
PRMT1 arginine methylation of MCM4 restricts ssDNA gap formation during DNA replication
https://www.biorxiv.org/content/10.64898/2026.06.03.729374v1
1 day ago
0
0
0
Saturating variant analysis of TERC redefines the human telomerase reverse transcription mechanism
https://www.biorxiv.org/content/10.64898/2026.06.01.728939v1
1 day ago
0
1
0
Multi-Omics Characterization of Human Molecular Responses to Spaceflight Across Two Independent Missions
https://www.biorxiv.org/content/10.64898/2026.06.01.729304v1
1 day ago
0
0
0
ATG16L2 creates a VAIL-dedicated heterodimer with ATG16L1
https://www.biorxiv.org/content/10.64898/2026.06.01.729256v1
2 days ago
0
1
1
Mitochondrial carrier SLC25A34 links clock, diet, and temperature control of interorganellar lipid cycling
https://www.biorxiv.org/content/10.64898/2026.05.30.724257v1
2 days ago
0
1
0
Development and validation of a genome-informed multiplex PCR for specific detection of typhoidal Salmonella serovars
https://www.biorxiv.org/content/10.64898/2026.06.01.729223v1
2 days ago
0
0
0
Optimized MALDI-TOF mass spectrometry enables reliable identification of freshwater snails from schistosomiasis-endemic areas in Mauritania
https://www.biorxiv.org/content/10.64898/2026.06.01.729200v1
2 days ago
0
0
0
Phosphorylation-dependent regulation of Hsp70 chaperones stimulates client recruitment
https://www.biorxiv.org/content/10.64898/2026.06.01.729190v1
3 days ago
0
3
1
Unravelling the role of a disordered chaperone in adaptation to environmental stress
https://www.biorxiv.org/content/10.64898/2026.06.01.729257v1
3 days ago
0
1
1
Macrocyclic Peptide Tools for Huntingtin-bound HAP40
https://www.biorxiv.org/content/10.64898/2026.06.02.729325v1
3 days ago
0
0
0
Reduced Myocardial Serine Synthesis Impairs Functional, Metabolic, and Redox Adaptations to Cardiac Stress
https://www.biorxiv.org/content/10.64898/2026.05.29.728910v1
3 days ago
0
0
0
Circular RNA aptamers act as superb sub-stoichiometric chaperones to prevent cytosolic TDP-43 condensation
https://www.biorxiv.org/content/10.64898/2026.06.01.729436v1
4 days ago
0
0
0
Better late than never: the impact of hatching time on Heterodera schachtii parasitism
https://www.biorxiv.org/content/10.64898/2026.05.29.728720v1
4 days ago
0
0
0
A replication hijacking mechanism for Tn3-family replicative transposition
https://www.biorxiv.org/content/10.64898/2026.05.30.728999v1
4 days ago
0
0
0
The Ets family transcription factor EHF suppresses senescence-associated inflammatory responses
https://www.biorxiv.org/content/10.64898/2026.05.31.728776v1
4 days ago
0
0
0
SRC Knockdown Impairs Proliferation, Migration, and Invasion While Promoting Apoptosis in HTR8/SVneo Trophoblast Cells via Activation of the PI3K/Akt/Bcl-2 Signaling Pathway
https://www.biorxiv.org/content/10.64898/2026.05.28.728375v1
5 days ago
0
0
0
An Integrating Sphere Based Method for Quantifying RNA Encapsulation Efficiency in Lipid Nanoparticles without Lysis
https://www.biorxiv.org/content/10.64898/2026.05.29.728751v1
5 days ago
0
0
0
Thousandfold Expansion Microscopy
https://www.biorxiv.org/content/10.64898/2026.05.31.729018v1
5 days ago
0
1
1
The defining features of intrinsic transcription terminators
https://www.biorxiv.org/content/10.64898/2026.05.29.728758v1
5 days ago
0
0
0
Detection of Pancreatic Cancer Using a Methylation-Specific PCR-Based Multi-Cancer Early Detection Test
https://www.biorxiv.org/content/10.64898/2026.05.27.728292v1
5 days ago
0
0
0
Osteopontin Upregulation Defines a Pre-Rupture State in Thoracic Aortic Aneurysms in Mice and Humans
https://www.biorxiv.org/content/10.64898/2026.05.27.728313v1
5 days ago
0
0
0
GAPVD1 regulates CSNK1D-dependent PER2 FASP phosphorylation
https://www.biorxiv.org/content/10.64898/2026.05.29.728667v1
5 days ago
0
0
0
Expanded Proteome Coverage Powered by Advanced Ion Processing Enables Deep Single-Cell Drug Response Subtyping in Human Stem Cell Derived Cardiomyocytes
https://www.biorxiv.org/content/10.64898/2026.05.29.728818v1
5 days ago
0
0
0
Ceramide Synthases Regulate Myristate-Induced Intestinal IRE1α Activation
https://www.biorxiv.org/content/10.64898/2026.05.28.728542v1
6 days ago
0
0
0
O-GlcNAc transferase regulates H2O2 production via p38 MAPK
https://www.biorxiv.org/content/10.64898/2026.05.27.728188v1
6 days ago
0
0
0
PAIR-link: a ligation-free strategy that joins two RNAs into a single sequence-preserving chimeric cDNA
https://www.biorxiv.org/content/10.64898/2026.05.29.728768v1
6 days ago
0
0
0
The b0+ Amino Acid Transporter Defines a Selenium-utilization Enterocyte Program in the Human Intestine
https://www.biorxiv.org/content/10.64898/2026.05.27.728150v1
6 days ago
0
0
0
Epigenetic Profiling of Human Insulinomas Reveals AP-1 Family as Critical Regulators of Beta Cell Maturation
https://www.biorxiv.org/content/10.64898/2026.05.29.728759v1
7 days ago
0
0
0
TgmRHel drives unified RNA processing of coxI mRNA generated from a complex mitochondrial genomic context
https://www.biorxiv.org/content/10.64898/2026.05.29.728635v1
7 days ago
0
0
0
Tetramerization and RNA-guided filament assembly control Schlafen-Argonaute antiphage defense
https://www.biorxiv.org/content/10.64898/2026.05.29.728809v1
7 days ago
0
1
0
RIG-I-like receptors sense replication stress through ribosomal DNA integrity to drive inflammation
https://www.biorxiv.org/content/10.64898/2026.05.27.728122v1
7 days ago
0
1
1
TDP1 drives MRE11-dependent and independent end resection during replication stress by TOP2 poisons
https://www.biorxiv.org/content/10.64898/2026.05.29.728668v1
7 days ago
0
0
0
RNA-binding proteins activate transcription through defined molecular grammars
https://www.biorxiv.org/content/10.64898/2026.05.29.728737v1
7 days ago
0
0
0
Modular engineering of an extracellular contractile injection system for protein delivery to mammalian and bacterial cells
https://www.biorxiv.org/content/10.64898/2026.05.27.728243v1
8 days ago
0
0
0
Microexon alternative splicing and feeding behavior in C. elegans.
https://www.biorxiv.org/content/10.64898/2026.05.26.727998v1
8 days ago
0
1
1
Molecular mechanism for the functional divergence between cohesin paralogs during meiosis
https://www.biorxiv.org/content/10.64898/2026.05.26.727825v1
8 days ago
0
0
0
Proton-gating of opioid receptors and isoform functionality
https://www.biorxiv.org/content/10.64898/2026.05.26.727816v1
8 days ago
0
0
0
c-MYC is Transcribed in a Circadian Manner and Acts as a Clock Disruptor whose Timing Minimizes its Impacts
https://www.biorxiv.org/content/10.64898/2026.05.26.727929v1
8 days ago
0
0
0
Leaky scanning translates a conserved ORF in the 3'UTR of RPL36A and regulates the expression of ribosomal protein L36a.
https://www.biorxiv.org/content/10.64898/2026.05.26.727855v1
8 days ago
0
0
0
Modulating proton sensing by the adenosine receptor A2
https://www.biorxiv.org/content/10.64898/2026.05.26.727808v1
8 days ago
0
0
0
The CCCH-type zinc-finger PfMD3 promotes translation for malaria parasite transmission
https://www.biorxiv.org/content/10.64898/2026.05.27.726058v1
8 days ago
0
0
0
ELOF1 is a core component of the promoter-proximal paused RNA polymerase II complex
https://www.biorxiv.org/content/10.64898/2026.05.26.728003v1
9 days ago
0
0
1
DORA: a dose-response autoencoder for interpretable transcriptome-to-viability prediction
https://www.biorxiv.org/content/10.64898/2026.05.27.728125v1
9 days ago
0
0
0
Load more
feeds!
log in