Dustin Updike
@dustinupdike.bsky.social
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Associate Prof, MDIBL | C. elegans germ granules | Hiding in the woods of Maine
reposted by
Dustin Updike
Navin B. Ramakrishna
3 months ago
Schematics of our increasing knowledge of in vivo human primordial germ cell development, and a summary of the exciting hPGCLC maturation protocols:
@dev-journal.bsky.social
@biologists.bsky.social
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C. elegans, ba ba ba.
#Worm25
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5 months ago
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Two cancelled flights, ten delays, and a 36-hour odyssey past Polyphemous, Scylla, Charybdis, and the Laestrygonians—but we finally made it to
#Worm25
!
5 months ago
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Ah, the joys of traveling anywhere from downeast Maine - our flight out of Bangor to
#Worm25
was cancelled. Delayed, but not deterred - we'll see all you worm folk tomorrow.
5 months ago
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Part of the puzzle unlocked. Excellent work from the Phillips and Montgomery labs.
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7 months ago
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Dustin Updike
Coleen Murphy
7 months ago
🧪#Celegans - I am very excited to announce the publication of our latest finding in transgenerational epigenetic inheritance (TEI) of learned pathogen avoidance - • C. elegans transgenerational avoidance of P. fluorescens is mediated by the Pfs1 sRNA and vab-1
www.science.org/doi/10.1126/...
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C. elegans transgenerational avoidance of P. fluorescens is mediated by the Pfs1 sRNA and vab-1
C. elegans’ TEI of learned pathogen avoidance is induced by a third bacterial small RNA, Pfs1, from P. fluorescens 15.
https://www.science.org/doi/10.1126/sciadv.adt3850
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Dustin Updike
Colin Conine
8 months ago
The first C. elegans paper from lab! We find that, similar to mammals, tRNA-fragments (or the new name in the field tDRs) accumulate in worm sperm and can transmit non-genetically inherited phenotypes to offspring. We also find an RNase that regulates their processing, showing that length matters
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reposted by
Dustin Updike
MDI Biological Laboratory
9 months ago
Science thrives because of our dedicated researchers, students, supporters, and community members. At MDI Bio Lab, we believe in the power of discovery, education, and collaboration. Thank you for
#standupforscience2025
, believing in science, and being part of our community!
#standwithscience
🧪 🤝
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Dustin Updike
Dr. Michael D. L. Johnson
9 months ago
Funding science is like betting on horses. Only with science, for each dollar you bet on a horse, you average getting two to three dollars in winnings. Also, you can bet on more than one horse in the field. Plus you learn something that up to that moment, no one knew before.
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Dustin Updike
Oded Rechavi
10 months ago
What an amazing discovery from Scott Kennedy's lab! A new splicing system that recognizes transposons and removes them from mRNAs!
t.co/3p3wyxkYXX
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https://www.biorxiv.org/content/10.1101/2025.02.14.638102v1?ct=
https://t.co/3p3wyxkYXX
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Dustin Updike
Derek Lowe
12 months ago
Fluorescently labeled proteins are essential to research. But we should never forget how messed-up their behavior can be. An example from condensates:
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Fluorescent Tags Are Basically Never Silent
https://www.science.org/content/blog-post/fluorescent-tags-are-basically-never-silent
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For you or someone you know? I have to say, it's pretty great up here.
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about 1 year ago
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reposted by
Dustin Updike
Abby Dernburg
about 1 year ago
Ru-upping this thread from last year since the paper is now out!
@chenshuliu.bsky.social
identified a Piezo-dependent mechanism that enables C. elegans to sniff out “bad eggs” and target them for destruction.
www.science.org/doi/10.1126/...
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you reached the end!!
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