Excited to share our latest paper! We found that large pieces of the human genome can transfer between cells upon direct contact, endowing recipient cells with heritable phenotypic changes. @cp-cell.bsky.social (1/7) www.cell.com/cell/fulltex...

Latest paper. We studied ATF4 in ageing in the fly. We find in contrast to previous suggestions that ATF4 suppression rather than activation extends lifespan. The study was largely conducted in an MSc project by Miriam Götz who showed an exceptional drive for science. www.pnas.org/doi/10.1073/...

The UK is one of only five of the richest 21 countries to see HLE decline. @ONS reports that healthy life expectancy is falling. BSRA advocates for increased funding in ageing research so we can all live healthier for longer. Dataset in the comments 👇 www.bbc.co.uk/news/article...

Travel Grants for #BSRA2026!!! Don't forget there is a seperate travel grant call *just* for BSRA 2026, our 75th annual meeting. This year in Oxford, it's promising to be a great meeting. bsra.org.uk/grants/ Like and share, or tag someone who should apply below👇

Tardigrades resist heavy DNA damage by actively repairing such lesions & expressing DNA-protective proteins. Yet, they are not immortal. How & why do they die? @morielab.bsky.social now shows that their Achilles' heel is DNA replication: duplicating your DNA... will kill you doi.org/10.1111/febs...

Need to profile DNA replication genome-wide? TrAEL-seq reveals replication patterns and fork progression in unsynchronised, unlabelled and unsorted cells Our revised protocol: • Provides far better data from mammalian cells • Includes 6-way multiplexing academic.oup.com/nar/article/...

Exciting new project in our lab @babrahaminst.bsky.social! We are working with @alesdantas.bsky.social at @newcastleuni.bsky.social to understand how extrachromosomal circular DNA mediates drug resistance in fungal pathogens Funded by @wellcometrust.bsky.social #ecDNA #eccDNA #Candida #Zymoseptoria

Post-doc job alert! Only a week left to apply for this post doc role, joining our team at the Babraham Institute @babrahaminst.bsky.social to explore ageing metabolism and epigenetics. babrahaminstitute.livevacancies.co.uk#/job/details...

Post-doc job alert! We have an exciting opportunity for a post doc to join our team at the Babraham Institute, exploring ageing metabolism and epigenetics. babrahaminstitute.livevacancies.co.uk#/job/details...

Our new Preprint describes an improved TrAEL-seq protocol: • Provides far better data from mammalian cells • Includes multiplexing for higher throughput TrAEL-seq reveals replication patterns and fork progression in unsynchronised, unlabelled and unsorted cells www.biorxiv.org/content/10.1...

If you're at the AGE meeting don't miss the BSRA Korenchevsky Award talk from Hanane Hadj-Moussa! Hanane's work shows that we can acheive excellent healthy ageing through metabolic rewiring, even on an unrestricted diet Profile: whova.com/embedded/spe... Preprint: www.biorxiv.org/content/10.1...

Is healthy ageing possible on a normal diet? Our latest Preprint describes metabolic re-engineering of yeast to avoid senescence The A2A mutant we created is super-fit late in life even on a rich high glucose diet www.biorxiv.org/content/10.1...

Congratulations to our PhD student Amy Wolstenholme for winning the Poster Prize at the EMBL Drug Resistance meeting #EESDrugResistance this week Amy's poster showed that circular DNAs providing copper resistance can be stably transmitted for hundreds of generations in yeast