Delighted to be part of this work from the Lopes lab identifying nucleoplasmic Lamin A/C as a key regulator of replication fork plasticity, acting via de novo heterochromatin and ADP-ribosylation to control RECQ1-mediated fork restart. Now in Nature Comm. 🎉Special efforts: @joannapaulson.bsky.social

Among the anti-recombinases, FIGNL1 rules them all. So much that inactivating it brings BRCA2-deficient cells to life. Who is responsible for RAD51 loading without BRCA2/FIGNL1, check out the paper to find out! Great collaboration with @raychaudhurilab.bsky.social www.science.org/doi/10.1126/...

Halloween borrel at the department 🎃 : our PhDs & Postdocs showed next-level creativity by revealing the hidden monstrous sides of their PIs! 👻😂 Absolutely hilarious & scary indeed😜… though I’m starting to wonder if that’s really how they see me 👀😅

I am very excited to share the newest paper of the lab, a huge amount of work led by our talented PhD student Maxime Galloy, in close collaboration with Andréanne Blondeau, our dedicated research assistant for 10 years! 🙌 www.cell.com/molecular-ce...

First preLights post from Jenny Singh (@jennysingh.bsky.social‬) She covers work showing that Lamin A/C maintains replication fork integrity during mild replication stress by modulating chromatin structure & restraining RECQ1 activity. #preprint #preLight ⬇️ prelights.biologists.com/highlights/n...

⏰🚨FINAL DEADLINE APPROACHING #BGFP25 's extended reg deadline is closing on 02 June 2025. This is your last chance to register and confirm your place at this fantastic conference 🧬! Join us in sunny Portugal this July and register now: bit.ly/3AnsVZF

A must for all DNA repair aficionados! Egmond DNA Repair Meeting → April 19–24, 2026 🇳🇱 ✔️ Confirmed top speakers ✔️ Ample opportunities for talks & posters Don’t miss it: dnarepairmeeting-egmond2026.com

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Exciting seminar series from Genome integrity italian Network (GiiN), chaired by myself and Raffaella Di Micco! Short talks (2x30’), at convenient time for EU/USA attendees. Big shots and raising stars in an expanding field. See flyers + link to receive email alerts. Please repost to your network!👇

Join us in Lisbon this July to learn how cells "Balance Genome Fidelity & Plasticity". deadline for talks extended and a # of fellowships are available to offset trainee registration. www.fusion-conferences.com/conference/1...

Happy to have contributed(along with PhD students @joannapaulson.bsky.social & Collin Bakker) to such great work from @lopeslab.bsky.social and team! www.biorxiv.org/content/10.1...

Online today @science.org 👀Molecular basis of FIGNL1 in dissociating RAD51 from #DNA and #chromatin by @alexcarver.bsky.social @layates.bsky.social et al. in @imperialcollegeldn.bsky.social @mskcancercenter.bsky.social www.science.org/doi/10.1126/...

What are your plans for October 2025? It would be a fantastic time to visit Norway for the Endogenous DNA Damage and Repair conference with a stellar set of speaker covering a wide range of topics. www.endodnadamage.com

Dear all, my first post! I have postdoc positions available if you would like to join my lab in beautiful Sussex by the Sea! Please contact me on [email protected]

behold our paper on Medusavirus nucleosomes. Fantastic work by Chelsea Toner, @nhoitsma.bsky.social, and Sashi Weerawarana This giant virus also encodes a linker histone, more about that in the paper 🧪👩‍🔬 🧵. www.nature.com/articles/s41...

Happy to share our new paper with Goran Kokic and the Svejstrup lab in Cell! We show that STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair. Great teamwork by Diana, Marta and Paula! www.cell.com/cell/fulltex...

What an exciting day for the lab at the Dutch Chromatin Meeting! Congrats to Ashutosh (a.k.a Vincent 😉)for winning the poster prize on 3D reorganization of stressed forks & Joanna for her fantastic talk on phase separation during replication stress. Proud of you guys! 🤩

Two back-to-back papers in Nature comms from mylab explore the link between destabilization of the actin cytoskeleton and aberrant base excision repair - passing through nuclear actin and the actin-dependent nucleosome remodeler INO80C.

The latest from our group, led by Megan Ostrowski and @martyyang.bsky.social, is now published in final form (www.cell.com/cell/fulltex...! Many thanks to our excellent peer reviewers for suggesting several experiments (including CAF-1 perturbation) to really improve the study =) #epigenetics

First post here! New paper from the lab! Profound synthetic lethality between FANCM and SMARCAL1: www.cell.com/molecular-ce...

Fantastic study… Congratulations Francesca n team! 👏

Being haiku-ed is an honor! You were so fast, too 🤩

New function for an 'old' chromatin remodeler: great collaboration with @nitikataneja.bsky.social and others. Fantastic work from our own @nhoitsma.bsky.social. Check out how SMARCAD1 contributes to resolving R-loops during replication, before they become a problem. www.biorxiv.org/content/10.1...

How are R-loops & conflicts rapidly resolved ahead of actively progressing forks? Is there a remodeler that associates with active forks, binds directly to R-loops, and senses & suppresses them? Check out our new study here!👇 www.biorxiv.org/content/10.1...