Latest paper. We studied ATF4 in ageing in the fly. We find in contrast to previous suggestions that ATF4 suppression rather than activation extends lifespan. The study was largely conducted in an MSc project by Miriam Götz who showed an exceptional drive for science. www.pnas.org/doi/10.1073/...

We also show higher body temperatures were selected for - again this was independent of growth.

Thermal physiology meets quantitative genetics - our new paper explores the drivers of body temperature in nestling sparrows #ornithology @jevbio.bsky.social academic.oup.com/jeb/article/...

What do the naked mole rat and bowhead whale (lives to ~200 years) have in common to explain their remarkable longevity? Enhanced DNA repair www.nature.com/articles/s41... erictopol.substack.com/p/a-long-awa...

Latest paper. Super interesting comparative biology on ageing in the bowhead whale. www.nature.com/articles/s41... Congrats to Denis Firsanov, Max Zacher, Jan Vijg, Andrei Seluanov, Vera Gorbunova, et al, for this work. Thanks for including us in this work and also Dan Hayman (excellent postdoc).

Come and study Biology at the University of Sheffield (UK)! We cover every aspect of biology and offer specialised degrees with plenty of module choice and research. Feel free to contact me should you want any information. A brilliant video made by our students: www.youtube.com/watch?v=syup...

Please help spread the word about our inaugural public lecture on Wednesday. Sign up and if you are in the ageing field it’s a great opp for your family to finally understand what you do! 😀 Thanks for your support 🙏 bsra.org.uk/events/bsra-...

Latest exciting work from me and @mirresimons.bsky.social (and the first bit of data from my @vivensa.bsky.social ECR Fellowship) now out as a preprint, looking at effects of knocking down individual spliceosome components on lifespan in vivo: www.biorxiv.org/content/10.1...

We present a novel idea of how aging evolves. This idea was developed together with Marc Tatar, and it was such a joy to think about. I think this is one of the best ideas I worked on for a while, ..or ever.. ;): arxiv.org/abs/2509.15911

Lifelong restriction of dietary valine has sex-specific benefits for health and lifespan in mice www.biorxiv.org/content/10.1...

#mTOR research field never ceases to amaze, what a tour de force! 👇🏼 mTORC1 senses glutamine and other amino acids through GCN2 | The EMBO Journal www.embopress.org/doi/full/10....

New preprint. ATF4 activation is thought to lead to longer lifespans. However, our study shows that suppression rather than activation extends lifespan in the fly. New Qs: how we can target ATF4 or its downstream targets to gain targeted longevity benefits. www.biorxiv.org/content/10.1...

A huge project has analysed more than 1,000 claims about the immunity of Drosophila fruit flies in scientific papers published over some 50 years go.nature.com/4lxhwJB

Proudly presenting Simon’s @simonsterson.bsky.social‬ paper on asymmetric apportioning of old mitochondria biasing intestinal stem cells for the Paneth cell linage through aKG-dependent metabolism @naturemetabolism.bsky.social www.nature.com/articles/s42... @helsinki.fi @metastem.bsky.social 🧵1/8

If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social

Our latest preprint…Adrien Franchet, Yuhong Jin et al @crick.ac.uk show that circulating glutamine drives brain sparing during nutrient restriction. Great collab with labs of Yaël Grosjean and Ian Gilmore. #metabolism #Drosophila #neuralstemcells www.biorxiv.org/content/10.1...

"More and more people are worried about the long-term effects of contact sports on the brain. In football (soccer), studies have found that repeatedly heading the ball can lead to memory problems and an increased risk of serious brain diseases." theconversation.com/... 1/4

Version of record in eLife on the trade-off between reproduction and survival (ageing) in birds. Well done Lucy! Conclusions: Limited evidence for trade-offs. Constraints appear in between-species variance only. Trade-offs may not be inherent to ageing. elifesciences.org/articles/87018

Lovely film about Tim Birkhead's long-term study of Guillemots on Skomer. More than half a century of study of this population: this kind of continuity critical for understanding vitality of these important populations. besjournals.onlinelibrary.wiley.com/doi/full/10.... vimeo.com/1063680641/2...

Latest preprint. We tested the idea that dietary restriction (DR) is an ancient response. www.biorxiv.org/content/10.1... Across Drosophila the lifespan phenotype and the transcriptomic response to DR are conserved. Yet, many genes were Diptera (fly) specific. Mechanisms may not be conserved…

Latest. Dan tested the importance of Drosophila immune cells by ablating or expanding them using conditional genetics. Turns out no lifespan phenotype, perhaps because there is compensation within the immune cell lineage. More exciting biology to discover. journals.biologists.com/jeb/article/...

Undersea rewilding initiative to restore a kelp forest in West Sussex is celebrating amazing results for marine biodiversity. Rewilding is needed just as much at sea as on land. www.bbc.com/news/article...

Don't forget to register & submit an abstract for #FusionAging25 in Malta this October! ☀️ ECR grants are also now live💰so visit the conference website for more information on how to apply: bit.ly/4bLiSw6

The reckless termination of grants at NIH continues www.washingtonpost.com/health/2025/...

🚨New preprint alert!!! We show using #Celegans that mothers control the #ribosome levels of their offspring depending on their diet. Pioneered by fantastic Sigma Pradhan (not yet on 🟦). #worms biorxiv.org/content/10.1.... 🧵

Just because they confirmed RFK Jr today, I am resharing this good news: No cervical cancer cases detected in vaccinated women following HPV immunisation publichealthscotland.scot/news/2024/ja...

Thanks to the more than *1100* members of the scientific community who have signed the letter to insist that the Royal Society remains true to values that we all hold dear but that Musk FRS has ridden roughshod over. Please keep signing & sharing. docs.google.com/forms/d/e/1F...

Our latest... Congrats to Seb Sorge, Victor Girard & coauthors for devising HolFast, a chemically defined (holidic) diet for #Drosophila development that performs almost as well as a yeast diet. If you study developmental #nutrition or #metabolism please try it out... www.cell.com/developmenta...

Definitely come to Alaska and absolutely don’t miss this superb Keynote from visionary aging researcher Daniel Promislow @dpromislow.bsky.social @americanaging.bsky.social @agingmidwest.bsky.social

Once more with feeling! Hey! Are you using a script to scrape FlyBase? Just stop. NOW. You're crashing the site for everyone. Yes, we mean YOU.

Great news! today.tamu.edu/2025/01/06/d...

Divorce rates predict reproductive success in little penguins: onlinelibrary.wiley.com/doi/10.1002/... #ornithology

Some minor corrections and changes. Now ready to be downloaded from @figshare.com > figshare.com/articles/fig...

Tired of having to explain this again and again, I made an info- graphic of #Drosophila stock keeping. Any comments? @bdsc.bsky.social @flybase.bsky.social

✨✨The 2025 Keystone Symposium on Aging and Gerotherapeutics is coming up and early bird registration ends today! Very excited about our speaker lineup. Check it out! www.keystonesymposia.org/conferences/...

Apply to "Drosophila genetics and genomics": experienced experts will teach you hands-on in classical strategies and cutting-edge experimental techniques to enhance your use of this powerful model organism for research, whilst connecting to scientists in your field. www.embl.org/about/info/c...

If knowledge is power; it follows that those that are in search of power but without knowledge attack knowledge rich institutions/individuals. It is imperative or even a moral obligation that these institutions/individuals wield their power in defense without fear.

Now official: our next @embl.org course on #Drosophila Genetics & Genomics will be held 3-8 Aug '25. Send in your applications! @bsdb.bsky.social @gensocuk.bsky.social @flybase.bsky.social @fly-eds.bsky.social @socdevbio.bsky.social @the-node.bsky.social @virtualflybrain.bsky.social

New to bluesky and looking to re-connect with aging and longevity research community members who transitioned to bsky.

Postdoc position available: Work with us at @mblscience.bsky.social on maternal age effects, #transgenerational inheritance, and #mitochondria. Cool project with a great model system. Postdoc salary at the MBL is well above the NIH pay scale! #GeroSky #aging recruiting.ultipro.com/MAR1033MBL/J...

A WHO team is to journey deep into the Congo to identify a mystery illness that appears to be killing at will. The zone in which 394 people are reported to have been sickened by a possible new Disease X – with up to 74 dead – is one of the most remote on earth. www.telegraph.co.uk/global-healt...

#Phd on #Aging #Ageing available in my group. Focus is long-read sequencing and splicing after treatment with DR and mTOR suppression in flies. #drosophila www.findaphd.com/phds/project...

* NEW #PhD * #Evolution #Ecology of Immune #Senesence in Wild Badgers - exciting project with me, @btschirren.bsky.social & our awesome collaborators @ APHA. Based at @exetercec.bsky.social in Cornwall, UK. !PLEASE SHARE! See www.animalsocieties.org and apply: www.exeter.ac.uk/study/fundin... 🌏 🧪 🦑

A recent update of our manuscript on the costs of reproduction & trade-offs underlying ageing using meta-analysis of brood size experiments in birds and fitness projections. elifesciences.org/reviewed-pre...

Looks like bluesky is going to be added to altmetrics! #philsky #academicsky

How does pollution impact behavioural evolution? We're looking for an awesome PhD student to find out. Project spans behaviour, genetics + ecotox, working with cherry shrimp @exetercec.bsky.social. Cosupervised with @lauraakelley.bsky.social and Dave Spurgeon at CEH. App + info tinyurl.com/yvthn7xn

Dear Bluesky, #science is more than pictures of stars. Thank you.