A Histone Code Functionally Linked to Replicative Senescence onlinelibrary.wiley.com/doi/full/10....

A reminder that senescent cells can be functional and play important physiological roles. So, when labs and companies talk about therapies that remove senescent cells, the devil is in the details: how, when, and which senescent cells? www.science.org/doi/10.1126/...

Five lifestyle tweaks to help you live well for longer www.bbc.com/future/artic...

Longitudinal Profiling of DNA Methylation Reveals Age-Varying CpG Sites and Novel Insights Into Aging Heterogeneity onlinelibrary.wiley.com/doi/full/10....

Integrative transcriptomic identification of cellular senescence beyond marker limitations www.biorxiv.org/content/10.6...

Systemic LINE-1 RNA in Plasma Extracellular Vesicles Drives Neuroinflammation and Cognitive Dysfunction via cGAS-STING Pathway in Aging onlinelibrary.wiley.com/doi/full/10....

Do saunas really boost your health? www.bbc.com/news/article...

Rejuvenation of white adipose tissue in a longitudinal heterochronic transplantation model www.biorxiv.org/content/10.6...

Senescent Cell Clearance Ameliorates Temporal Lobe Epilepsy and Associated Spatial Memory Deficits in Mice onlinelibrary.wiley.com/doi/10.1002/...

Recommendations for biomarker data collection in clinical trials by longevity biotechnology companies www.nature.com/articles/s41...

Senotherapeutics for Brain Aging Management www.mdpi.com/2035-8377/17...

Progeroid Syndrome with Signs of Autophagy Dysfunction in the Naked Mole Rat (Heterocephalus glaber) link.springer.com/article/10.1...

Distinct precursor landscape of subcutaneous and visceral fat in development and aging www.cell.com/cell-reports...

Genomic Perspective on Heterogeneity of Organs and Body Aging onlinelibrary.wiley.com/doi/full/10....

Stress-induced organismal death is genetically regulated by the mTOR–Zeste–Phae1 axis www.pnas.org/doi/10.1073/...

Maximal human lifespan in light of a mechanistic model of aging www.biorxiv.org/content/10.6...

The impacts of different dietary restriction regimens on aging and longevity: from yeast to humans link.springer.com/article/10.1...

Spermidine deficiency induces BNIP3/LC3B-mediated mitophagy in the salivary glands of accelerated aging mice www.sciencedirect.com/science/arti...

Mesenchymal thymic niche cells enable regeneration of the adult thymus and T cell immunity www.nature.com/articles/s41...

Toward precision longevity: aging interventions in the single-cell atlas era www.frontiersin.org/journals/agi...

Codon bias coevolves with longevity www.biorxiv.org/content/10.6...

How to measure, analyze, and interpret age-related changes in Caenorhabditis elegans: lessons for mechanistic and evolutionary theories of aging www.sciencedirect.com/science/arti...

Ecological Perspectives on Aging onlinelibrary.wiley.com/doi/full/10....

Anti-PD-L2 immunotherapy is efficacious against melanoma in aged hosts through IL-17 and IFNγ signalling www.nature.com/articles/s41...

Mitochondrial RNA cytosolic leakage drives the SASP www.nature.com/articles/s41...

Restoring youth to old immune cells: mRNA therapy turns back the clock www.nature.com/articles/d41...

The role of gut microbiome in aging-associated diseases: where do we stand now and how technology will transform the future www.tandfonline.com/doi/full/10....

Fluorescence lifetime clocks quantify senescence and aging www.nature.com/articles/s43...

Senolytic-Resistant Senescent Cells Have a Distinct SASP Profile and Functional Impact: The Path to Developing Senosensitizers onlinelibrary.wiley.com/doi/full/10....

Senolytic Treatment With Dasatinib and Quercetin Reshapes Influenza-Specific CD8 T Cell Responses During Infection in Aged, Vaccinated Mice onlinelibrary.wiley.com/doi/full/10....

The aging transcriptome: a condition-dependent response to a deteriorating soma www.biorxiv.org/content/10.6...

PRKN-Mediated Ubiquitin-Proteasome Degradation of METTL3 Promotes Cellular Senescence onlinelibrary.wiley.com/doi/full/10....

Above and beyond senescence and CAR T cell: advances and future perspectives www.frontiersin.org/journals/imm...

Senescent host-derived extracellular vesicles potentiate antitumor immunity via bystander T cell activation www.biorxiv.org/content/10.6...

An unbiased comparison of 14 epigenetic clocks in relation to 174 incident disease outcomes www.nature.com/articles/s41...

Engineering ATP Import in Yeast Uncovers a Synthetic Route to Extend Cellular Lifespan www.biorxiv.org/content/10.1...

Senolytic therapy increases replicative capacity by eliminating senescent endothelial cells www.sciencedirect.com/science/arti...

Leveraging Comparative Phylogenetics for Evolutionary Medicine: Applications to Comparative Oncology academic.oup.com/emph/advance...

Not Aging but Calorie Restriction Strongly Affects Protein Oxidation in Heart and Brain Mitochondria onlinelibrary.wiley.com/doi/full/10....

Aged brain multi-omic integration captures immunometabolic and sex variation www.biorxiv.org/content/10.1...

Biological resilience as a crucial determinant in preventing age-associated chronic diseases www.frontiersin.org/journals/phy...

A sex-adjusted 7-biomarker clinical aging clock for translational preventative medicine www.nature.com/articles/s41...

Redox Regulation of Complement Pathway Activation in Aging and Related Diseases www.mdpi.com/2076-3921/15...

Revealing the genetic architectures underlying organ-specific aging based on proteomic data www.nature.com/articles/s41...

Lipofuscin accumulation in aging and neurodegeneration: a potential “timebomb” overlooked in Alzheimer’s disease link.springer.com/article/10.1...

Prediction and analysis of anti-aging peptides using data augmentation and machine learning algorithms link.springer.com/article/10.1...

Tenascin-C from the tissue microenvironment promotes muscle stem cell maintenance and function through Annexin A2 www.nature.com/articles/s42...

Cyrene: a novel geroprotective compound that extends lifespan and healthspan in C. elegans and Drosophila www.nature.com/articles/s41...

Preliminary Evidence for Increased Histone Succinylation as a Potential Epigenetic Marker for Longevity onlinelibrary.wiley.com/doi/full/10....

Cognitive aging clock based on Explainable artificial intelligence www.nature.com/articles/s41...