Very happy to share our paper rdcu.be/eUImj out today in @natcellbio.nature.com 🎉🎉🎉 We uncover an unexpected role for endogenous Xist RNA in regulating X-linked genes that escape X-inactivation.

Want to image cells protecting the embryo during early development? We're hiring! 1 Postdoc, 1 PhD student, and 1 Research Technician. Come to Barcelona! www.embryobioimaging.com

🔔 Please share 🔔 I have two open developmental biology/genetics/evo-devo PhD project vacancies for October 2026 start. 1 = 🐚 🐌 🔬(embryos!!) ⏱️📆 DEADLINE 15th DEC 📆⏱️ (competition) sleightlab.com/vacancies/ 2 = 🦪 🐌 🧬 ⏱️📆 DEADLINE 14th JAN 📆⏱️(fully funded) sleightlab.com/phd-vacancy-2/

The new issue @cp-devcell.bsky.social brings the final form of our opossum heterochrony work www.cell.com/developmenta... And it also brings two great papers from @oliveringe.bsky.social @santoslab.bsky.social and @tobyandrews.bsky.social @rashmi-priya.bsky.social 🙌 great #DevBio from @crick.ac.uk

Join @mpercharde.bsky.social Lab at the MRC LMS! We have an 18mo postdoc position to cover a couple of projects (maternity leave and paper revisions). The projects are focussed on chromatin in early mouse embryos and metabolism in mouse embryonic stem cells and pluripotency.

We are recruiting PhD students! Two days left to apply for the LSI studentships - deadline Nov 26 www.exeter.ac.uk/research/ins... and a few more for the SWBio studentships - deadline Dec 3 www.swbio.ac.uk/programme/pr... Please repost or forward to prospective students that might be interested!

Scientific journals: we don’t want you using generative AI because it makes shit up. Same journal: here is an AI summary or evaluation of this paper. This might be more useful than the actual abstract or paper that the authors freaking wrote Same journal: AI cover art which makes no sense? Oooh!

Our lab is actively looking for posdocs and there is NOW an Open Call for Postdoc contracts (3 years) here: www.aei.gob.es/en/announcem...

And the paper is finally out! Thank you to the reviewers for improving the content, and to everyone who contributed along the way. A very nice way of finishing the transition from Melbourne to Cambridge. www.nature.com/articles/s41...

Out today, our take on 6-methyladenine #6mA evolution in Eukaryotes @natgenet.nature.com. We asked a simple question, is really DNA 6mA common across the eukaryotes? The answer is "yes" if you're a unicellular eukaryote 🦠, not so if you're multicellular 🐝🌱🍄. www.nature.com/articles/s41... 1/9

📣 SAVE THE DATE Next X-inactivation meeting in Sapporo, Japan, 19-23 October 2026. Visit x-inactivation-meeting.org to join our mailing list. 🧬 speakers @dandergassen.bsky.social @marnieblewitt.bsky.social @heard65.bsky.social @crougeulle.bsky.social @sexchrlab.bsky.social @zhouqi1982.bsky.social

🚨Reposts appreciated‼️If I had read this PhD offer five years ago, I wouldn’t have hesitated for a second to apply 😉 Passionate about gene regulation, chromatin, and developmental biology? Just contact @radaiglesiaslab.bsky.social at @ibbtec.bsky.social 🧬✨ #PhD #3DGenome

Beautiful work confirming that DNA demethylation dynamics are different between eutherians and marsupials during early development 🦘 We knew about opossums but it's also true in dunnarts!

OFERTA DE EMPLEO (por favor difundir): Ofrecemos un contrato predoctoral de 4 años asociado a nuestro proyecto PID2024-157249OB-I00. El objetivo del proyecto es evaluar un nuevo mecanismo patológico según el cual la competición entre promotores puede llegar a ocasionar enfermedades congénitas 👇

🚨 We're hiring! 🚨 Our lab at the University of Málaga, Spain🇪🇸 is looking for a bioinformatician researcher for a postdoc position (1+1 years). Check the ad, and if you're interested, get in touch! 📅 Starting date early 2026, with some flexibility. 🙏Please, RT!

Crick group leaders work across disciplines, supported by core funding and mentoring to build ambitious, curiosity-driven research. Apply now to join us ➡️ www.crick.ac.uk/careers-stud...

Thrilled to share my main postdoc work with @jamesbriscoe.bsky.social We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions 🧵👇 www.biorxiv.org/content/10.1...

Help us to promote this DevBiol course (in Spanish) ¡Nuevo curso gratuito de Biología del Desarrollo (en español)! Aprende sobre los procesos que dan origen a la vida Cupos limitados → forms.gle/sfSV1GTae2nC... Detalles y programa: drive.google.com/file/d/1-9dd... #BiologíaDelDesarrollo

Our latest 📢 We generated isogenic iPSCs with XX, XY, XO and XXY karyotypes to study sex chromosome effects 🧫 While XX and XY transcriptomes are similar, XO cells showed an important effect of the Y and inactive X @crick.ac.uk @stemcellreports.bsky.social www.sciencedirect.com/science/arti...

Come join the #LondonEvoDevo network half day meeting, hosted at @ucl.ac.uk on Friday November 7th, 2025. Submit your abstract by Oct 27th (or your interest in joining) here: forms.gle/TRbdrCkQTcY2.... Friendly vibes and free registration. More info here: londonevodevo.co.uk.

Success rates for Europe’s leading research grants are declining as a surge in applications far outweighs the funds available go.nature.com/479Sni6

My lab will be recruiting a PhD student this year. Have a look and apply if it sounds interesting! adroverlab.com/open-call-fo...

We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions. Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research. Apply now ➡️ www.crick.ac.uk/careers-stud...

We are recruiting PhD students! If you are interested in evolutionary neuroscience, consider applying: www.crick.ac.uk/careers-stud...

The Francis Crick Institute PhD programme recruitment is now live and our lab is recruiting. If you are interested in studying the role of the extracellular matrix in tissue dynamics during development and cancer please apply – link below. Please share. www.crick.ac.uk/careers-stud...

It is with great sadness that we share the news of the death of our founder, colleague, mentor and friend, Professor Sir John Gurdon. His vision and dedication will continue to inspire generations of scientists. 🔗 www.gurdon.cam.ac.uk/nobel-laurea...

Interested in understanding how new cell types evolve? Consider joining our group for a PhD!

Fully-funded 4-year PhD Opportunities available at the @crick.ac.uk , including a project in our lab on human #embryomodels Feel free to share with anyone interested, and apply through the online portal before 5th November! 👏 www.crick.ac.uk/careers-stud...

We've updated our first #preprint from the lab! A collaboration with @jamesbriscoe.bsky.social 🔥 now including in vivo 🐭&👤 embryo data www.biorxiv.org/content/10.1...

Last days to apply! Cool project, cool cities! :-) (Please repost! 🙏)

NEW PODCAST: ‘A Question of Science’ with Professor Brian Cox. In every episode, panels of scientists and experts answer audience questions about some of the biggest issues facing us today. Listen to the first episode, ‘Can we live forever?’: lnk.to/AQOSAgeingBB

Edith Heard our new CEO shares ten lessons from her life in science, from curiosity, courage and coffee to the secrets of our genetic code. www.crick.ac.uk/news/2025-09...

1/7 Really happy to see my PhD work published in ✨Developmental Cell✨ today! We find human endoderm is specified by two developmental trajectories 🔀, and the choice between alternate routes is dictated by the combinatorial BMP4/Activin signalling. www.cell.com/developmenta...

I'm a bit late to the party over here. I'll be advertising a BBSRC-funded postdoc position soon. So if anyone wants to solve some outstanding questions in limb development - please get in touch. We have a variety of models and approaches (everything from stem cells to sharks). towerslab.weebly.com

We now have an open post-doc position in the lab: crick.wd3.myworkdayjobs.com/External/job... Please apply if you have a background in functional genomics or a related field and are eager to develop methods to map variant effects at scale.

🚨 We’re recruiting PhD students! 🚨 Join the Stem Cell Biology and Evolution lab at @lsiexeter.bsky.social to study planarians, stem cells & evolution. 2 projects available - 1 week left to apply! Interested and no PhD yet? Apply now. Or help us spread the word! 🙌 www.exeter.ac.uk/research/ins...

Super excited that our latest work is out! We use optogenetics to dynamically control and study the formation of morphogen gradients. If you are interested in optogenetic tools and/or how cells shape and process extracellular signals, check out @jamesbriscoe.bsky.social's thread and the paper.

In #opossums and other #marsupials, #GeneExpression follows familiar rules, but at an unusual pace. In PNAS Journal Club: www.pnas.org/post/journal... #DevelopmentalBiology #evolution #embryo #transcriptome

Nanog beyond pluripotency! Another example of the repurposed role of pluripotency factors after implantation. www.embopress.org/doi/full/10.... and consistent with Miguel Manzanares and Julio Sainz de Aja work on Nanog repressing Pou3f1 journals.biologists.com/bio/article/...

After nearly twenty years in the making, our attempt at understanding what makes the chaetognath phylum so unique has finally been published! www.nature.com/articles/s41... with #LauraPiovani @dariagavr.bsky.social @alexdemendoza.bsky.social @chemamd.bsky.social and others /1

@pnas.org Front Matter posted a nice summary of our recent work on opossum development @crick.ac.uk Thanks Amy McDermott for the highlight, and @amartinezarias.bsky.social for the comments. It says '6 min read', so now might be a good time www.pnas.org/post/journal...

Looking for a postdoc position? Join us at the Tucker group! We have chocolate Digestives on a weekly basis

Thrilled to bits to see our latest work online in Dev Cell! 🥳 We wanted to know how cells build functional organs with precision🫀🫁📏 Here we show how coupling of cell shape and organ function fine tunes the form and contractile power of the developing #zebrafish heart 1/n tinyurl.com/cell-stretch

Dev biologists! 3-yr postdoc position at King's, collaboration with Trizzino lab @marcotrizzino.bsky.social modelling CHD3 neural crest. We are looking for postdocs with mad embryology skills @the-node.bsky.social #developmental @ccrb27.bsky.social thenode.biologists.com/jobs/postdoc...

Paper alert! 🚨 Something new from us, and this time it's not sex chromosome related 😱 All led by @sermenchero.bsky.social who used the opossum as a model to understand developmental heterochrony. Transcriptional and morphological progression of dev programs are decoupled www.cell.com/developmenta...

🔥🔥🔥🔥🔥🔥 Worth a read if interested in developmental timing & heterochronies. What a beautiful work in an unusual model organism. Congrats Sergio et al!!!!

Remarkable finding supporting the existence of the interactions between two independent modules, #morphogenetic and #genetic, in #embryonic development. Acceleration of anterior genetic program in opossum @sermenchero.bsky.social‬ www.cell.com/developmenta... short 🧵

Thrilled to share the story stemming from my PhD! We used mESC neural differentiation, genome editing and bulk & single-cell approaches to uncover how ZIC2 controls early neural fate by playing a dual and sequential regulatory role as a promiscous pioneer and a selective lineage-specific activator.

Thrilled to share that our latest work on marsupial heterochrony is now online at @cp-devcell.bsky.social @cellpress.bsky.social @lab-turner.bsky.social @crick.ac.uk We used scRNAseq to understand the asynchronous progression of developmental programmes in marsupials www.cell.com/developmenta...

🚨 I’m looking for two enthusiastic scientists to join our team at Cambridge to explore the molecular mechanisms of lactation, early nutrition, and their long-term impact on health. Apply here: 👉 RA: www.jobs.cam.ac.uk/job/51988/ 👉 Postdoc: www.jobs.cam.ac.uk/job/51984/ Please share 🔬👩‍🔬