🏆 MRS Sue Eccles Early Career Investigator Award: Jose M. Adrover

🚀 Two weeks to go! The ECR Meeting brings together early-career scientists driving the next wave of metastasis research. ⚡ Don’t miss: 💡 Inspiring talks from rising leaders 💬 Community-led discussions 🌍 A global metastasis community 🗓️ Register by Nov 18 ➜ bit.ly/4qyxE0o Program ➜ bit.ly/4qtpVR9

This review from Ambreen, @adrover.bsky.social et al. explores cancer-elicited changes to #neutrophil behaviour and proposes ways in which these may contribute to cardiovascular pathology. rupress.org/jem/article/... 📘 In #Cytokines collection: rupress.org/jem/collecti... #Cytokines2025

My lab will be recruiting a PhD student this year. Have a look and apply if it sounds interesting! adroverlab.com/open-call-fo...

We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions. Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research. Apply now ➡️ www.crick.ac.uk/careers-stud...

🔥Trio Fatale: Neutrophils, NETs and Necrosis 👉 authors.elsevier.com/a/1lk-k3qNrU... We summarized for @cp-immunity.bsky.social "Neutrophils drive vascular occlusion, tumour necrosis and metastasis" published in @nature.com by @megeblad.bsky.social @adrover.bsky.social rdcu.be/eFdau Congrats!

A new model of #TumorNecrosis👹 Tumor CXCL1➡️myeloid skewing➡️ Ly6C-low Neutrophil forms intravascular #NeutrophilExtracellularTrap➡️ Intratumoral vascular occlusion➡️ Pleomorphic Necrosis-to-Metastasis a role of TGFβ @adrover.bsky.social @megeblad.bsky.social Nature 2025 www.nature.com/articles/s41...

Heart of the matter: #Neutrophils, #cancer, and #CardiovascularDisease. New review from Saira Ambreen, Afshan McCarthy, Andrés Hidalgo, and Jose Adrover @adrover.bsky.social @crick.ac.uk: rupress.org/jem/article/... #TumorImmunology #CardiovascularBiology #InnateImmunity #inflammation

#Cancer patients display an elevated burden of #CardiovascularDisease. This review from Ambreen, @adrover.bsky.social et al. explores cancer-elicited changes to #neutrophil behaviour and proposes ways in which these may contribute to cardiovascular pathology. rupress.org/jem/article/...

Here's our take on how neutrophils can be a critical link between cancer and cardiovascular disease! "Heart of the matter: Neutrophils, cancer, and cardiovascular disease", just published @jem.org with Saira Ambreen, Afshan McCarthy and @drusqui.bsky.social rupress.org/jem/article/...

Thanks to Cancer Discovery for highlighting our manuscript with such a nice summary! Intravascular Neutrophil-Derived NETs Drive Tumor Necrosis and Metastasis aacrjournals.org/cdnews/news/...

@cdi-einstein.bsky.social Director @jaguirreghisolab.bsky.social co-leads a study showing how viral infections can trigger via IL6 signaling awakening of dormant breast cancer cells in lungs. CDI's research focuses in part on host variations controlling the timing of residual cancer awakening

Nature research paper: Neutrophils drive vascular occlusion, tumour necrosis and metastasis go.nature.com/4lzilSb

Happy to share our latest preprint doing low cell number (mini-bulk) and single cell #proteomics on tumour associated neutrophils from human glioblastoma where we find multiple functional states that would be invisible to scRNAseq, some showing pro-tumoural states with potential therapeutic value

A fascinating study reports that neutrophils and NETs actively induce tumor necrosis. Congratulations, BDP @megeblad.bsky.social and @adrover.bsky.social on your latest publication in @nature.com.

As a new postdoc in my lab (@cshlnews.bsky.social → @jhu.edu) @adrover.bsky.social (now @crick.ac.uk) saw NETs in tumors—I shrugged. But he looked closer in 3D: NETs block tumor vessels, driving necrosis, hypoxia, EMT & metastasis. 🔗 www.nature.com/articles/s41... @jhu-bdps.bsky.social @nature.com

I’m happy to share our latest work on tumour necrosis! During my time in the @megeblad.bsky.social lab, we found that tumour necrosis is not a passive phenomenon secondary to tumour growth, but an active phenomenon driven by neutrophils and NETs! Thread below: (1/13) www.nature.com/articles/s41...

Are you curious about how cancer impacts immune cell progenitors and how that changes mature cell function? My lab will soon be recruiting a Postdoctoral Fellow. If you are interested, please find more information here: adroverlab.com/open-positio...

💥 Really excited to say that our paper with Karin de Visser and @dewitlab.bsky.social is now online! A beautiful story to culminate years of great collaboration and teamwork at the @nkinl.bsky.social. A 🧵 www.sciencedirect.com/science/arti...

I had a wonderful time in the Tumor Microenvironment Working Group session! #AACR25 Thanks everyone for the warm welcome and lively discussion!

William Hill is presenting his work on air pollutants in lung adenocarcinoma in a fascinating session exploring ageing and environmental factors in the development and spread of lung cancer. #AACR25 | @drwilliamhill.bsky.social | @crick.ac.uk

If you’re attending #AACR25 stop by and say "Hi!" to our colleagues in @cancergrand.bsky.social at stand 2327, and Cancer Tools at stand 2424 in the exhibition hall.

I’m thrilled to be presenting our work next Monday the 28th at the #AACR25 in beautiful Chicago!

OBS #Immunology Seminar Neutrophils and regulation of skin physiology 📆 Thu, 10th April, 12 pm EDT/5 pm CET 🎙️ Speaker @alazozcan.bsky.social @yalesph.bsky.social @drusqui.bsky.social @cnic @nature.com 📣 Moderator @eugecc.bsky.social us02web.zoom.us/meeting/regi...

I had a wonderful time! Great conference and speakers! Thanks @casanova-acebes.bsky.social @sancholab.bsky.social and Carlos Silvestre for the great work organizing such an amazing meeting!

Last contribution to the understanding of #neutrophil biology. Superb work from Tommaso, @alazozcan.bsky.social, and Jackson that I had the pleasure to contribute to and see growing during my time at @drusqui.bsky.social lab.

Excited to post for the first time to present our exciting new paper @Nature. The fruit of massive work by Tommaso Vicanolo, @alazozcan.bsky.social and Jackson Li, and our superb collaborators Laiguan and Stefan Uderhardt. True teamwork! Free link: rdcu.be/eeeA2 www.nature.com/articles/s41...

The Postdoctoral Career Development Fellowship for Clinicians call at the Francis Crick Institute is open until the 30th of March, and our lab is participating this year! More info here: adroverlab.com/open-call-po...

High fat diet feeding impairs neutrophil phagocytosis, bacterial killing, and neutrophil-induced hematopoietic regeneration @jimmunol.bsky.social doi.org/10.1093/jimm...

🚨 Last chance to register for BSI Oxford and @immunologyoxford.bsky.social's Oxford Immunology Symposium! #OIS25 📅 Date: 24 March 2025 📍 Location: Oxford Mathematical Institute 🎤 Featuring talks on adaptive & innate immunity and interdisciplinary insights Register NOW: t.co/tlXp9dddqo

Thrilled to share our new work on #aging in the murine hematopoietic system! There is a lot here- stem cell numbers, self-renewal rates, mutation rates, mutation signatures, clonal fitness, environmental effects...

Get ready for #WorldImmunologyDay2025! 🌎 Join us at The Francis Crick Institute on 24 April to explore "The immune system and your brain" 🧠 Hosted by @claudiahammond.bsky.social and run by @britsocimm.bsky.social, @natureportfolio.nature.com and @crick.ac.uk Register for FREE now: bit.ly/41m8kP9

My lab is participating in this call at the Crick. It is an exciting opportunity for postdoctoral clinicians to advance their research careers within a world-leading multidisciplinary biomedical discovery research institute. Apply now for a fully funded 1-year fellowship in London!

Applications for our Future Leaders in Biomedical Sciences scholarships are now open. These scholarships are aimed at students of Black or mixed Black heritage who wish to undertake a PhD in biological or biomedical sciences. Learn more and apply. ⬇️ www.crick.ac.uk/careers-and-...

📢 Are you a cancer researcher willing to strengthen ties with Spain? Are you looking for new opportunities or collaboration partners? Or are you in Spain searching for a lab abroad? Then take a look at #ASEICAInternacional and sign up here👇 bit.ly/4geGD0e. Please share the link! @aseica.bsky.social

I had a lovely time today and great discussions with faculty and students at @cambridgebiocampus.bsky.social and @crukcamcentre.bsky.social Thanks to the Cambridge Immunology Network and Maike de la Roche for the kind invitation and for being such wonderful hosts!

Join us tomorrow🙌

Upcoming seminar: 🎓Jose M. Adrover, @crick.ac.uk 📢"Neutrophils drive vascular occlusion, pleomorphic tumour necrosis, and metastasis" 📅 4-5PM, Thurs 20 Feb 📍JCBC @cambridgebiocampus.bsky.social @adrover.bsky.social @uniofcam.bsky.social #MedSky #AcademicSky 🧪

So excited to share the latest work from the amazing Serena Lucotti and the rest of the David Lyden Lab out now in Cell. Super honored to have been able to help out in this great work! news.weill.cornell.edu/news/2025/02... www.cell.com/cell/abstrac...

Which of our 104 abstract topics at the #EACR2025 Congress does your research fit into? Abstract submission is open until 06 March! 🤩 2025.eacr.org/abstracts

Crick researchers have found that certain aggressive lung cancer cells can develop their own electric network, similar to the body’s nervous system. This can allow tumour cells to go ‘off grid,’ making them harder to treat. www.crick.ac.uk/news/2025-02...

Make sure you, your trainees, and anyone else who might listen to you understands what "indirects" actually are, how they are established, and what Universities contribute. H/T @rodallab.bsky.social Please share widely! www.youtube.com/watch?v=yxTD...

We’re looking for enthusiastic PhD candidates out there! 👉Fully funded PhD positions 👉US-like Lab Rotations 👉Inspiring microenvironment Apply by March 11.