This Childhood Cancer Awareness Month, we’re highlighting progress against childhood solid tumours. Our teams are working to advance next-gen CAR-T therapies & protein degraders—bringing hope for a future with safer, more effective treatments www.cancergrandchallenges.org/news/tacklin...

Published today in @aacrjournals.bsky.social Imran Noorani & @magnushaughey.bsky.social share the first evidence that ecDNA can build up in the healthy brain before tumours form in #glioblastoma — pointing to new early intervention strategies. 👉 www.cancergrandchallenges.org/news/ecdna-u...

Interesting @economist.com piece on #CancerGrandChallenges team Mutographs, Phil Jones (@sangerinstitute.bsky.social) & Sci Committee Chair Charles Swanton. Their work reshapes how we think about cancer’s origins - A great read if you have access. 👉 www.economist.com/science-and-...

New opinion piece by Tobias Janowitz at @cshlnews.bsky.social‬ & team CANCAN: Of Hope from Fading Will. How cancer influences brain–body communication, why #cachexia may begin as an adaptive response, and how patient-reported symptoms can guide new interventions 👉 www.cell.com/neuron/fullt...

Congratulations to #CancerGrandChallenges MATCHMAKERS team member Regina Barzilay for making the 2025 #TIME100 list of global #AI leaders! At ‪@aihealthmit.bsky.social‬, Regina has advanced cancer prediction and antibiotic discovery—and is now tackling our TCR challenge to transform #immunotherapy

@natrevendo.nature.com‬ examines the links between obesity, T2DM, inflammation & microbiome disruption to rising early-onset colorectal cancer. Featuring teams PROSPECT, CANCAN, and co-authors 👉 www.nature.com/articles/s41... #EOCRC #TeamScience

An interesting perspective in Molecular Cell from Cristina Mayor-Ruiz (team PROTECT), Georg E. Winter (team KOODAC), Alessio Ciulli (team KOODAC and co-authors - Opportunities in proximity modulation: Bridging academia and industry #CancerGrandChallenges

“...exploring why people don’t get cancer... could give us a greater understanding... and could potentially lead to new ways to think about cancer prevention” - Karen Vousden, @crick.ac.uk & #CancerGrandChallenges Scientific Committee Member talking about our cancer avoidance challenge.

Fascinating interview! Howard Chang shares insights on ecDNAs and his long-standing collaboration with Paul Mischel, both of which were central to his time as a co-investigator on #CancerGrandChallenges team eDyNAmiC whilst at Stanford University.

After nearly a decade of leadership, Margaret Grayson MBE reflects on her time as Chair of the #CancerGrandChallenges Advocacy Panel. Thank you Margaret for embedding the voices of those affected by cancer into discovery research. features.cancerresearchuk.org/cancergrandc...

Prof Kimmie Ng, one of our leading #CancerGrandChallenges scientists, discusses the drivers behind early onset colorectal cancer with ‪The New York Times #EOCRC nytimes.com/2025/08/02/w...