Turning complex cell therapies into real treatments for children is a major challenge. But new research from the NexTGen team published in @natmed.nature.com shows that it's possible. 📄 Read more: www.cancergrandchallenges.org/news/teachin...

Research from team eDyNAmiC explores how ecDNA may "hitchhike" on chromosomes during cell division. Led by Sihan Wu and Yipeng Xie, the study provides new insights on how ecDNA is inherited as cancer cells divide. Read the paper, published in @natcellbio.nature.com 👇 www.nature.com/articles/s41...

Team PROSPECT has published new findings that reveal younger generations appear to be ageing faster biologically, showing a clear birth cohort effect that mirrors the rising incidence of early-onset cancers. 👉Learn more @yincaoscd.bsky.social cancergrandchallenges.org/news/is-acce...

It’s the final day of our Cancer Grand Challenges Conference: Cancer and the host at @royalsociety.org. Today brings a final opportunity to build connections, refine ideas and reflect on what’s emerged so far. Follow along for highlights from the closing sessions. #CancerGrandChallenges

Day two of our Cancer Grand Challenges Conference: Cancer and the host is underway! Today, discussions go even further into mechanism, connection and complexity, starting with the neurobiology of cancer. Follow along for our key insights... #CancerGrandChallenges

We’re ready for day one of the Cancer Grand Challenges Conference: Cancer and the host at @royalsociety.org 🙌 To those following along remotely, stay tuned for our highlights, insights, and reflections. #CancerGrandChallenges

The REWIRE-CAN team is shaking up the rule book. Led by Bart Vanhaesebroeck, this team is challenging the traditional approach of treating cancer by blocking cancer growth and survival signals by instead hyperactivating them. Learn more about REWIRE-CAN 👉 www.youtube.com/watch?v=bcnk...

New findings from team PROMINENT in @science.org highlights new ways to think about cancer prevention by modulating clonal dynamics and ensuring that dangerous clones never emerge. Learn more: www.cancergrandchallenges.org/news/competi...

Meet the ILLUMINE team on the hunt to discover whether (and how) dark proteins influence some of the toughest cancers. Learn more about ILLUMINE 👉 www.youtube.com/watch?v=vYYh...

We're bringing together scientists from across the world to explore cancer in its full systemic context. From 17–19 June, we'll be at The Royal Society in London exploring how the host shapes cancer. Follow along for highlights, insights and ideas throughout the week. #CancerGrandChallenges

Studying cancer avoidance isn’t straightforward. It means finding individuals who don’t develop cancer, and analysing them at scale. That level of research needs global collaboration, and Cancer Grand Challenges makes it possible. Read about this work ➡️ www.technologynetworks.com/cancer-resea...

A future without cancers starts with understanding its origins. Meet the CAUSE Team on a mission to uncover the hidden triggers of cancer. Learn more about CAUSE 👉 www.youtube.com/watch?v=F8Yj...

Final call for abstracts! Spatial biology is reshaping cancer research, from tumour evolution and the microenvironment to treatment responses. Join leaders at the Cancer Grand Challenges Conference: Spatial Biology. 📍 Royal Society, London 📅 1–3 Sept 2026 ⏰ Deadline: 31 May Submit ➡️ lnkd.in/eM7b6GX5

We bring together experts from across disciplines to enable bold, collaborative science 🤝 Read all about Team InteroCANCEption in this new Technology Networks article ➡️ https://www.technologynetworks.com/tn/articles/decoding-the-crosstalk-between-the-nervous-system-and-cancer-412682

Our very own David Scott will be speaking at a @uclgrandchallenges.bsky.social event next week 🎤 Don’t miss the chance to hear from him! Find out more and register ➡️ www.eventbrite.co.uk/e/tackling-g...

Why are some people immune to cancer? Learn more about team ATLAS, led by Paul Bastard, @institutimagine.bsky.social👉 www.youtube.com/watch?v=dFJA... ATLAS is funded by @cancerresearchuk.org and Torrey Coast Foundation through Cancer Grand Challenges.

Congratulations to Professor Johnanna Olweus, member of team MATCHMAKERS, for winning the King Olav's Cancer Research Prize for groundbreaking work harnessing donor T cells to target cancer more effectively. Read more about the work of team MATCHMAKERS ➡️ www.cancergrandchallenges.org/matchmakers

Spatial biology is transforming cancer research 🔬 We're bringing together global leaders in cancer research, technology development and clinical practice for breakthrough science, bold ideas and new collaborations. Secure your place today ➡️ www.cancergrandchallenges.org/conferences/...

New speaker announced 📣 We're delighted to welcome Adrian Hayday, an immunologist at @crick.ac.uk, to our Cancer Grand Challenges Conference: Cancer and the host! Secure your place and join the conversation ➡️ www.cancergrandchallenges.org/conferences/...

The InteroCANCEption team wants to know if the brain can sense a tumour by picking up small signals from inside the body through the nervous system. Learn more about InteroCANCEption, led by @leanneli.bsky.social at @crick.ac.uk 👉 www.cancergrandchallenges.org/interocancep...

Professor Greg Hannon was the chair of the Cancer Grand Challenges Conference: Spatial Biology. Following the deeply sad news of the passing of Greg, we are sharing that the meeting will still go ahead in his memory. (1/2)

Exciting new work from Professor Chris Garcia, co-investigator on MATCHMAKERS 👏 Team MATCHMAKERS is funded through Cancer Grand Challenges by @cancerresearchuk.org, the National Cancer Institute and @themarkfdn.bsky.social

We are delighted that Leanne Li from @crick.ac.uk will speak at the Cancer Grand Challenges Conference: Cancer and the host. Leanne will speak on the bidirectional interplay between the nervous system and cancer. View the programme and register here 👇 www.cancergrandchallenges.org/conferences/...

#AACR26 shows what’s possible when global researchers unite to accelerate cancer progress. Our Head of Research, @ldelarica.bsky.social shares his reflections and highlights key scientific shifts shaping the field: www.cancergrandchallenges.org/news/reflect... @theaacr.bsky.social

Introducing peptidiens! Congratulations to the TransCODE consortium on this exciting tour-de-force in @nature.com: nature.com/articles/s41... We look forward to seeing what’s next as lead authors Sebastiaan van Heesch and John Prensner take on our dark proteome challenge as part of team ILLUMINE!

A new study from team OPTIMISTICC, published in @cellpress.bsky.social, shows that tumour-resident microbes are largely confined to cancers of the orodigestive tract. Together with team PROSPECT, they have generated a new resource and analytic pipeline. 👇 cancergrandchallenges.org/news/are-mic...

🚨The last few places are available for the Cancer Grand Challenges Conference: Cancer and the host Check out the programme which is now live and available to view online: cancergrandchallenges.org/conferences/... Register now to secure your place!

Congratulations to Charles Swanton, Mariam Jamal-Hanjani and colleagues on their fascinating analysis of the evolution of lung cancer metastasis published in Nature! www.nature.com/articles/s41...

In this week's issue of Nature, a great review from the Baker lab on the future of de novo protein design, and work from the Papagiannakopoulos lab revealing the mechanisms by which the integrated stress response regulates immune evasion. www.nature.com/nature/volum...

Congratulations to the newly elected #NASmembers from our Cancer Grand Challenges community 👏 Proud to see this recognition by the @nationalacademies.org for Doreen Cantrell, Chuan He, Stephen Liberles and Mike Stratton. Very well deserved! 🎊 www.nasonline.org/news/2026-na...

If you missed our Special Session at the #AACR Annual Meeting, you can still catch the key insights in the latest edition of Discover 👇 Take a closer look at the science with Allan Balmain and Mike Stratton: features.cancergrandchallenges.org/impact/

Final places are still available to attend the Cancer Grand Challenges Conference: Cancer and the host Register now to secure your place: eventbrite.co.uk/e/grand-chal... 🗓️Wednesday 17 – Friday 19 June 2026 🚨Registration closes Friday 1 May 2026 📍The Royal Society, London

New research in @nature.com shows how a toxin from a common gut bacterium disrupts the colon lining, which may contribute to colorectal cancer. This work was led by Cancer Grand Challenges team OPTIMISTICC’s Max White and Cynthia Sears. Read more: www.cancergrandchallenges.org/news/finding...

Our first-of-its-kind Special Session at #AACR26 brought together Cancer Grand Challenges teams shaping the future of cancer research. @theaacr.bsky.social Learn more about our teams’ latest advances and the upcoming Cancer Grand Challenges Conference: Cancer and the host 🔗 bit.ly/m/Cancer-Gra...

How does patient advocacy add value to cancer research? We spoke with Patrick McGuire, Chair of the Cancer Grand Challenges Advocacy Panel, about his newly published article in @cellpress.bsky.social. 🔗 www.cell.com/cell/abstrac...

Team eDyNAmiC is proposing a more holistic perspective by integrating extrachromosomal DNA (ecDNA) into the broader Hallmarks of Cancer framework. Read why in a new review published today in @cellpress.bsky.social www.cell.com/cell/fulltex...

Drawing on experience from Cancer Grand Challenges, we set out a practical framework for designing, supporting, and evaluating large‑scale collaborative research. 🌍 Published in @cellpress.bsky.social, we examine what it truly takes to enable global team science: sciencedirect.com/science/arti...

Less than 1 week to go until our Cancer Grand Challenges panel at #AACR. Hear insights from our exceptional panellists, and join us afterwards for a networking reception. Mark your calendar and add it to your AACR itinerary: www.abstractsonline.com/pp8/#!/21436... @theaacr.bsky.social

Join us for a first-of-its-kind Cancer Grand Challenges session at #AACR 2026 This special panel will bring together leading researchers from some of our teams: CANCAN, SPECIFICANCER, PROMINENT and Mutographs - delving into the breakthrough discoveries driving real progress. See you there!

In a special episode, Professor Hannah Fry and Michael Stevens explore the exciting work of some of our Cancer Grand Challenge teams - ATLAS, eDyNAmiC, and REWIRE-CAN. Listen to the takeover episode now: cruk.org/restisscience, in partnership with @cancerresearchuk.org ​

How do “super-avoiders” manage to stay cancer-free? Set up to investigate this is Paul Bastard and team ATLAS – one of five newly funded teams awarded $25m (£20m) through Cancer Grand Challenges. Watch the takeover episode (on YouTube): youtu.be/hAjvmBReo-8

Team #PROSPECT has revealed how the epigenome “remembers” inflammation, priming cells for cancer risk in mice. We spoke with @snaga13.bsky.social and Jason Buenrostro about what these findings mean for patients, and what the future holds. Learn more: www.cancergrandchallenges.org/news/the-epi...

Abstract submissions deadline EXTENDED! 💡 Don’t miss the chance to present your research alongside an outstanding panel of speakers. Submit your abstract by Friday 27th March: cancergrandchallenges.org/conferences/...

Final call for abstracts! This week is the last chance to submit your abstract for the #CancerGrandChallenges Conference: Cancer and the host cancergrandchallenges.org/conferences/... 🚨 Submit by Friday 20th March for the opportunity to join an outstanding line-up of speakers #CancerResearch

Next week is the final week to submit abstracts for Cancer and the Host: www.cancergrandchallenges.org/conferences/... 📥 Abstract deadline: 20 March 🗓️ 17–19 June 2026 📍The Royal Society, London This conference brings together leading researchers to explore cancer as a systemic disease. Read more 👇

The Cancer Grand Challenge Summit brings together our research teams, global network of partners, funders and patient advocates. Yesterday, we announced five new global teams who will take on five new challenges. Meet the new teams here 👉https://features.cancergrandchallenges.org/newteams/

We are excited to launch Discover, our annual progress magazine showcasing a year of extraordinary scientific breakthroughs and the latest #CancerGrandChallenges announcements. 🔗 Read the newest edition here: features.cancergrandchallenges.org

📰 News announcement! www.cancergrandchallenges.org/new-teams-an... We’re thrilled to welcome five world-leading scientific teams, each awarded up to £20 million, to take on some of the toughest unanswered questions in #CancerResearch. Find out more about the teams and their challenges.

🧬 New #ecDNA @natrevcancer.nature.com review by team #eDyNAmiC @stanfordmedicine.bsky.social @scripps.edu 👉 doi.org/10.1038/s415... Funded by: @cancerresearchuk.org #TheNationalCancerInstitue, #EmersonCollective and The Kamini & Vindi Banga Family Trust #CancerResearch #CancerInnovation

🎧 Podcast feature: Prof. Kimmie Ng from #CancerGrandChallenges team #OPTIMISTICC on #Podnosis with @gliadkovskaya.bsky.social. She explores the challenges of colorectal cancer rise in younger people. ▶️ www.fiercehealthcare.com/providers/ho... #CancerResearch #ColorectalCancer #CancerInnovation