🧬 New #ecDNA @natrevcancer.nature.com review by team #eDyNAmiC @stanfordmedicine.bsky.social @scripps.edu 👉 doi.org/10.1038/s415... Funded by: @cancerresearchuk.org #TheNationalCancerInstitue, #EmersonCollective and The Kamini & Vindi Banga Family Trust #CancerResearch #CancerInnovation

🎧 Podcast feature: Prof. Kimmie Ng from #CancerGrandChallenges team #OPTIMISTICC on #Podnosis with @gliadkovskaya.bsky.social. She explores the challenges of colorectal cancer rise in younger people. ▶️ www.fiercehealthcare.com/providers/ho... #CancerResearch #ColorectalCancer #CancerInnovation

In the UK, nearly 1 in 2 people will get cancer in their lifetime. Today is World Cancer Day – a global day to raise awareness of cancer, and take action against it 🌍 Share this post to help us raise awareness. #WorldCancerDay #WCD2026

Behind every challenge we fund is a patient who can’t wait. This #WorldCancerDay, we’re celebrating the researchers and partners pushing cancer research forward — and looking ahead to what’s next. ▶️ Watch vimeo.com/1121197514?s... #CancerResearch #CancerInnovation #UnitedByUnique

🎉 Congrats to #CancerGrandChallenges team members elected to the 2026 @theaacr.bsky.social Academy Fellows** 🎉 👏 Kimberly Stegmaier (PROTECT) 👏 Ben Cravatt (eDyNAmiC) 👏 Garry P. Nolan (STORMing) 👏 Anthony G. Letai #NCI Honouring leaders advancing cancer research. 🔗 www.aacr.org/about-the-aa...

Read about #CancerGrandChallenges Team #KOODAC’s innovative study, featured this week in @the-independent.com 👇 🔗 independent.co.uk/news/health/... Funded through @cancergrand.bsky.social l by @cancerresearchuk.org , @institut-cancer.bsky.social & #Kika. #CancerResearch #ImmunoOncology #MYC

🎉 Congratulations to Zhijian “James” Chen on receiving the 2026 Japan Prize in Life Sciences. 👉Read the official announcement here: 🔗https://www.japanprize.jp/en/press_releases20260121.html #JapanPrize #LifeSciences #ScienceNews #Immunology #ResearchImpact #JamesChen #GlobalScience #STEM

Team #KOODAC ’s first @cellpress.bsky.social paper uncovers how MYC helps solid tumours evade immune detection—revealing a new model with major implications for immunotherapy. Read the story behind the science 👇 Q&A: shorturl.at/7FXUw Paper: shorturl.at/DYuWO #CancerResearch #ImmunoOncology #MYC

New paper out from Cancer Grand Challenges team MATCHMAKERS 🚀 Design of compact, soluble SMART MHCs to better study T cell recognition. Read the full article here📄 www.pnas.org/doi/10.1073/... #CancerImmunology #Immunotherapy #CancerResearch #Oncology #TranslationalScience #ProteinEngineering

🧬 Not all cells in the same tissue behave the same. In skin, neighbouring cells can respond very differently to identical cancer. 🔗 www.cancergrandchallenges.org/news/tissue-... #CancerResearch #TissueSpecificity #TeamScience

A key new dimension of extrachromosomal DNA biology uncovered by the team from eDyNAmiC. Led by Paul Mischel @Stamford and Howard Chang, with key contributions from collaborators including Luke Gilbert @UCSF from team PROMINENT. 📖 Read in @cellpress.bsky.social: doi.org/10.1016/j.ce...

🎟️ Register for the #CancerGrandChallenges conference – Cancer and the host 📝 Register now 📥 Abstract deadline 20 March 🗓️ 17–19 June 2026 📍@The Royal Society, London 🔗 cancergrandchallenges.org/conferences/cancer-and-the-host

Researchers Nikolaos Sgourakis and John Maris from team NexTGen (co-funded by @themarkfdn.bsky.social) created a discovery system to identify new antigens in neuroblastoma. 📖 Read the Science Advances paper: doi.org/10.1126/scia... #CancerResearch #neuroblastoma #CancerGrandChallenges

Register now for the #CancerGrandChallenges conference Spatial biology. A gathering of global leaders in research, technology, & clinical care. 📝 Register now 📥 Abstract deadline 15 May 🗓️ 1 - 3 September 2026 📍The Royal Society, London 🔗 cancergrandchallenges.org/conferences/spatial-biology

The #CancerGrandChallenges impact reports reflect not just research milestones — but the power of global collaboration and visionary thinking to tackle some of cancer’s toughest challenges. 🔗 Explore the full impact reports here: lnkd.in/eGctd2rD #CancerResearch #TeamScience

We are thrilled to share that two leaders from the Cancer Grand Challenges community have been elected Fellows of the European Academy of Cancer Sciences (EACS). ✨ Johanna Olweus from the MATCHMAKERS team ✨ Peter Campbell from the Mutographs team 🔗 www.europeancanceracademy.eu/news/new-eac...

🎙️ Team Mutographs has been featured on the latest episode of The Rest is Science podcast, produced by @cancerresearchuk.org. ➡️ Listen: youtu.be/WGUBDeJ8MPM?... ➡️ Find out more about the Mutographs team’s journey & mission: www.cancergrandchallenges.org/mutographs #CancerResearch #GlobalHealth

🎊 Arafath Najumudeen from the team Rosetta, and his lab, have been awarded a @erc.europa.eu Consolidator Grant! Read more about the Najumudeen lab in the latest edition of Discover, the Cancer Grand Challenges' annual progress magazine 🔗 lnkd.in/dkfU_cWc #ERCCoG

📢 New Impact Report from SPECIFICANCER, the team unravelling one of cancer biology’s hardest puzzles: tissue specificity. A huge thank you to the team and thanks to our co-funders, @themarkfdn.bsky.social and @cancerresearchuk.org for supporting global science. 🔗 lnkd.in/dQC-iHmK

What if we could spot #cancer before it strikes — or while it’s still treatable? A new study published in @rsnasky.bsky.social is bringing us a step closer to that goal. 🔗 Read more doi.org/10.1148/radi... Congratulations to Joseph Lo, Shelley Hwang and the #CancerGrandChallenges PRECISION team.

Read the newly published impact report from the SPECIFICANCER team that reshaped our understanding of tissue specificity. Thanks to our co-funders, @themarkfdn.bsky.social, for supporting the #CancerGrandChallenges team and global science. 🔗 lnkd.in/eDrQ9guu

Register today to join the conversation that reframes cancer from being about the tumour to being about the host-tumour dialogue. 📝 Register today 🗓️ 17–19 June 2026 📍 The Royal Society, London 🔗 lnkd.in/ejup_Wbj

Explore how cancer research can prepare to unlock the full potential of data-driven innovation at the Cancer Research UK upcoming Data-driven cancer research conference in Edinburgh from 24-26 February 2026. Standard rate ticket registration closes 9 January 2026. 🎟️ Register now: cruk.ink/48aRoi0

🧬 Sponsor the #CancerGrandChallenges Spatial biology conference and join the community redefining how we see cancer. Help accelerate the next generation of spatial approaches that could revolutionise cancer diagnosis and treatment. Find out more: lnkd.in/e-7iZF6d

The new paper from SPECIFICANCER, published in @natureportfolio.nature.com reveals that it’s not just the mutation that matters — it’s where in the liver that mutation appears. Congratulations to the team (co-funded by @themarkfdn.bsky.social). 👉 Read more: lnkd.in/eTVh9YY6

🎉 Congratulations to @kinglhung.bsky.social‬ from team eDyNAmiC for receiving the prestigious prize and for having his essay, “Oncogenes out of context: Cancer genes break free from the regulatory constraints of chromosomes”, published in @science.org. 📖 Read more - lnkd.in/ekMqXC6J

We’re proud to share that 25 individuals from our international #CancerGrandChallenges community have been named among the @clarivate.com #highlycited2025. To every awardee across our community congratulations, and thank you for your leadership and impact 👏. Read more ow.ly/y23050XohmV

That’s a wrap for Future Leaders' Conference 2025! This conference wasn’t just about sharing what’s been done—it was about igniting what comes next. The optimism and connections we witnessed will drive real progress in tackling some of the hardest questions in cancer #FLC25 #CancerGrandChallenges

🔬 New research from #CancerGrandChallenges team PROSPECT explores possible links between diet and risk of bowel polyps in younger women. 🔗 Read more www.cancergrandchallenges.org/news/an-asso...

“Take the most exciting options, take risks and be bold” Words from Karen Vousden, Principal Group Leader at @crick.ac.uk and #CancerGrandChallenges Scientific Committee member, at day one of our Future Leaders’ Conference 2025 #FLC25

Members of NexTGen (co-funded by @themarkfdn.bsky.social), Nikolaos Sgourakis & John Maris, contributed to a new Nature paper from David Baker’s lab showing AI-designed antibodies with atomic-level precision A potential game-changer 👉 nature.com/articles/s41586-025-09721-5

We’re shifting how we think about cancer. Join the conversation that reframes cancer from being about the tumour to being about the host-tumour dialogue. 📝 Registration opens Monday 1 December 🗓️ 17–19 June 2026 📍The Royal Society, London 🔗 cancergrandchallenges.org/conferences/cancer-and-the-host

Great to hear Iain Foulkes join @break-cancer.bsky.social's @boehmjesse.bsky.social, @su2c.bsky.social's Julian Adams & NUT Carcinoma Alliance's Maddie Musselman at @milkeninstitute.org #MIHealthSummit to discuss how global collaboration can drive innovation in cancer research #CancerGrandChallenges

💡 New research from the #CancerGrandChallenges NexTGen team offers a way to make CAR T-cell therapy more effective — even against cancers that try to hide. 📖 Read the open-access paper in Nature Cancer: doi.org/10.1038/s43018-025-01056-4 #Immunotherapy #CART #PaediatricOncology #CancerResearch

🎉 Congratulations to Sir Mike Stratton (Team Lead) and Paul Brennan (Co-Investigator) of team Mutographs who have been awarded a @erc.europa.eu Synergy grant of €10.4m to continue researching the association between early-onset colorectal cancer and the colibactin mutational signature.

We're so grateful to our partners at the @themarkfdn.bsky.social for supporting the NexTGen team and helping to make their research possible. Thank you to all our #CancerGrandChallenge partners who make progress possible 👏

Team NexTGen, featured in @washingtonpost.com discussing their CAR T-cell immunotherapy trial. Thank you to @themarkfdn.bsky.social for supporting global science - working together to tackle one of the toughest challenges in cancer. 👉 If you have access - www.washingtonpost.com/science/2025...

Discover is here — our annual progress magazine showcasing a year of extraordinary scientific breakthroughs from across the #CancerGrandChallenges community. 👉 Read the full magazine here: www.cancergrandchallenges.org/discover-a-y...

We are thrilled that Charles Swanton, Chair of the #CancerGrandChallenges Scientific Committee, has been elected to the @nam.edu. Please join us in congratulating Charlie on this prestigious and well-deserved honour 👏 #CancerResearch #TeamScience

A new @nature.com Reviews Drug Discovery article highlights the first candidate drug to combat #cachexia — a major step toward treating cachexia, a devastating condition affecting many people with cancer. 🔗 Read the full article: www.nature.com/articles/d41... #CancerResearch

New research from team PROMINENT (@nlbigas.bsky.social), published in @nature.com, uncovers clues why men face a higher risk of bladder cancer and reveals that tobacco smoke acts as a promoter, not an initiator, in bladder cancer development. Read more: www.cancergrandchallenges.org/news/early-c...

“If we can stop cachexia, we can help patients live better — and longer.” - Tobias Janowitz, Co-Lead of team CANCAN. If you have access, discover how their work could change the way we treat one of cancer’s most overlooked challenges 👉 www.thetimes.com/uk/science/a... #CancerGrandChallenges

#CancerGrandChallenges IMAXT in @nature.com: Using CloneSeq-SV, the team tracked ovarian cancer clones and found: • Resistant clones often exist from diagnosis • ctDNA spotted recurrence ~8 months earlier than imaging • Actionable drivers (e.g. ERBB2) can be revealed www.nature.com/articles/s41...

Targeted protein degraders could change how we treat childhood cancers. John Buell of team KOODAC explains how our global team is working to develop safer, more effective therapies through #CancerGrandChallenges. Find out more: koodac.com/scientific-e...

Today marks the 1st #CancerCachexiaAwarenessDay. Cachexia affects up to 80% of people with advanced cancer. Our #CANCAN team is uncovering its biology & building the world’s first virtual cachexia institute. 🔗 www.cancergrandchallenges.org/news/demysti...

This Childhood Cancer Awareness Month, we’re highlighting progress against childhood solid tumours. Our teams are working to advance next-gen CAR-T therapies & protein degraders—bringing hope for a future with safer, more effective treatments www.cancergrandchallenges.org/news/tacklin...

Published today in @aacrjournals.bsky.social Imran Noorani & @magnushaughey.bsky.social share the first evidence that ecDNA can build up in the healthy brain before tumours form in #glioblastoma — pointing to new early intervention strategies. 👉 www.cancergrandchallenges.org/news/ecdna-u...

Interesting @economist.com piece on #CancerGrandChallenges team Mutographs, Phil Jones (@sangerinstitute.bsky.social) & Sci Committee Chair Charles Swanton. Their work reshapes how we think about cancer’s origins - A great read if you have access. 👉 www.economist.com/science-and-...

New opinion piece by Tobias Janowitz at @cshlnews.bsky.social‬ & team CANCAN: Of Hope from Fading Will. How cancer influences brain–body communication, why #cachexia may begin as an adaptive response, and how patient-reported symptoms can guide new interventions 👉 www.cell.com/neuron/fullt...

Congratulations to #CancerGrandChallenges MATCHMAKERS team member Regina Barzilay for making the 2025 #TIME100 list of global #AI leaders! At ‪@aihealthmit.bsky.social‬, Regina has advanced cancer prediction and antibiotic discovery—and is now tackling our TCR challenge to transform #immunotherapy