Great to hear Iain Foulkes join @break-cancer.bsky.social's @boehmjesse.bsky.social, @su2c.bsky.social's Julian Adams & NUT Carcinoma Alliance's Maddie Musselman at @milkeninstitute.org #MIHealthSummit to discuss how global collaboration can drive innovation in cancer research #CancerGrandChallenges

💡 New research from the #CancerGrandChallenges NexTGen team offers a way to make CAR T-cell therapy more effective — even against cancers that try to hide. 📖 Read the open-access paper in Nature Cancer: doi.org/10.1038/s43018-025-01056-4 #Immunotherapy #CART #PaediatricOncology #CancerResearch

🎉 Congratulations to Sir Mike Stratton (Team Lead) and Paul Brennan (Co-Investigator) of team Mutographs who have been awarded a @erc.europa.eu Synergy grant of €10.4m to continue researching the association between early-onset colorectal cancer and the colibactin mutational signature.

We're so grateful to our partners at the @themarkfdn.bsky.social for supporting the NexTGen team and helping to make their research possible. Thank you to all our #CancerGrandChallenge partners who make progress possible 👏

Team NexTGen, featured in @washingtonpost.com discussing their CAR T-cell immunotherapy trial. Thank you to @themarkfdn.bsky.social for supporting global science - working together to tackle one of the toughest challenges in cancer. 👉 If you have access - www.washingtonpost.com/science/2025...

Discover is here — our annual progress magazine showcasing a year of extraordinary scientific breakthroughs from across the #CancerGrandChallenges community. 👉 Read the full magazine here: www.cancergrandchallenges.org/discover-a-y...

We are thrilled that Charles Swanton, Chair of the #CancerGrandChallenges Scientific Committee, has been elected to the @nam.edu. Please join us in congratulating Charlie on this prestigious and well-deserved honour 👏 #CancerResearch #TeamScience

A new @nature.com Reviews Drug Discovery article highlights the first candidate drug to combat #cachexia — a major step toward treating cachexia, a devastating condition affecting many people with cancer. 🔗 Read the full article: www.nature.com/articles/d41... #CancerResearch

New research from team PROMINENT (@nlbigas.bsky.social), published in @nature.com, uncovers clues why men face a higher risk of bladder cancer and reveals that tobacco smoke acts as a promoter, not an initiator, in bladder cancer development. Read more: www.cancergrandchallenges.org/news/early-c...

“If we can stop cachexia, we can help patients live better — and longer.” - Tobias Janowitz, Co-Lead of team CANCAN. If you have access, discover how their work could change the way we treat one of cancer’s most overlooked challenges 👉 www.thetimes.com/uk/science/a... #CancerGrandChallenges

#CancerGrandChallenges IMAXT in @nature.com: Using CloneSeq-SV, the team tracked ovarian cancer clones and found: • Resistant clones often exist from diagnosis • ctDNA spotted recurrence ~8 months earlier than imaging • Actionable drivers (e.g. ERBB2) can be revealed www.nature.com/articles/s41...

Targeted protein degraders could change how we treat childhood cancers. John Buell of team KOODAC explains how our global team is working to develop safer, more effective therapies through #CancerGrandChallenges. Find out more: koodac.com/scientific-e...

Today marks the 1st #CancerCachexiaAwarenessDay. Cachexia affects up to 80% of people with advanced cancer. Our #CANCAN team is uncovering its biology & building the world’s first virtual cachexia institute. 🔗 www.cancergrandchallenges.org/news/demysti...

This Childhood Cancer Awareness Month, we’re highlighting progress against childhood solid tumours. Our teams are working to advance next-gen CAR-T therapies & protein degraders—bringing hope for a future with safer, more effective treatments www.cancergrandchallenges.org/news/tacklin...

Published today in @aacrjournals.bsky.social Imran Noorani & @magnushaughey.bsky.social share the first evidence that ecDNA can build up in the healthy brain before tumours form in #glioblastoma — pointing to new early intervention strategies. 👉 www.cancergrandchallenges.org/news/ecdna-u...

Interesting @economist.com piece on #CancerGrandChallenges team Mutographs, Phil Jones (@sangerinstitute.bsky.social) & Sci Committee Chair Charles Swanton. Their work reshapes how we think about cancer’s origins - A great read if you have access. 👉 www.economist.com/science-and-...

New opinion piece by Tobias Janowitz at @cshlnews.bsky.social‬ & team CANCAN: Of Hope from Fading Will. How cancer influences brain–body communication, why #cachexia may begin as an adaptive response, and how patient-reported symptoms can guide new interventions 👉 www.cell.com/neuron/fullt...

Congratulations to #CancerGrandChallenges MATCHMAKERS team member Regina Barzilay for making the 2025 #TIME100 list of global #AI leaders! At ‪@aihealthmit.bsky.social‬, Regina has advanced cancer prediction and antibiotic discovery—and is now tackling our TCR challenge to transform #immunotherapy

@natrevendo.nature.com‬ examines the links between obesity, T2DM, inflammation & microbiome disruption to rising early-onset colorectal cancer. Featuring teams PROSPECT, CANCAN, and co-authors 👉 www.nature.com/articles/s41... #EOCRC #TeamScience

An interesting perspective in Molecular Cell from Cristina Mayor-Ruiz (team PROTECT), Georg E. Winter (team KOODAC), Alessio Ciulli (team KOODAC and co-authors - Opportunities in proximity modulation: Bridging academia and industry #CancerGrandChallenges

“...exploring why people don’t get cancer... could give us a greater understanding... and could potentially lead to new ways to think about cancer prevention” - Karen Vousden, @crick.ac.uk & #CancerGrandChallenges Scientific Committee Member talking about our cancer avoidance challenge.

Fascinating interview! Howard Chang shares insights on ecDNAs and his long-standing collaboration with Paul Mischel, both of which were central to his time as a co-investigator on #CancerGrandChallenges team eDyNAmiC whilst at Stanford University.

After nearly a decade of leadership, Margaret Grayson MBE reflects on her time as Chair of the #CancerGrandChallenges Advocacy Panel. Thank you Margaret for embedding the voices of those affected by cancer into discovery research. features.cancerresearchuk.org/cancergrandc...

Prof Kimmie Ng, one of our leading #CancerGrandChallenges scientists, discusses the drivers behind early onset colorectal cancer with ‪The New York Times #EOCRC nytimes.com/2025/08/02/w...