Last chance! Early bird rates and oral presentation abstract submissions for Lorne Genome 𝐞𝐧𝐝 𝐍𝐨𝐯𝐞𝐦𝐛𝐞𝐫 𝟕𝐭𝐡, 𝟐𝟎𝟐𝟓 - only one week away: https://www.lornegenome.org/registrations We have a fantastic lineup of national and international speakers: https://www.lornegenome.org/speakers. Join us!

À ne manquer sous aucun prétexte!

#ESMO25 | New insights from the SOHO-01 study presented by Prof. NIcolas Girard @institutcurie.bsky.social: Molecular factors and ctDNA dynamics may help predict outcomes in patients with HER2-mutant #NSCLC treated with sevabertinib, paving the way for more personalized care. #medonc #lungcancer

1/10 Genome maintenance by telomerase is a fundamental process in nearly all eukaryotes. But where does it come from? Today, we report the discovery of telomerase homologs in a family of antiviral RTs, revealing an unexpected evolutionary origin in bacteria. www.biorxiv.org/content/10.1...

⚠️ Paper alert: Using a novel CRISPR screening approach, we mapped the entire regulatory network controlling Xist—key for X-chromosome inactivation. 👉 We discover how sex and development signals are decoded at a single gene locus. www.nature.com/articles/s41... 👇 Bluetorial

Job alert! We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks? See also on the forum: forum.image.sc/t/research-e...

"Transposable elements are vectors of recurrent transgenerational epigenetic inheritance" Congrats Vincent Colot and team! www.science.org/doi/10.1126/...

Professor Fuller is brilliant and you need to read what she has to say.

▶️ Pour en savoir plus ⏩ Lire l'actu : curie.fr/actualite/di... ⏩ Lire la publication : www.nature.com/articles/s41...

Congrats Charlène!

#1 Centromeres are epigenetic loci defined by CENP-A, positioned in unmethylated DNA flanked by highly methylated regions. Our work, published in @natgenet.nature.com in collaboration with @naltemose.bsky.social investigates the role of DNAme at human centromeres www.nature.com/articles/s41...

We had #four interdisciplinary teams, integrating dev-bio, evolution, tissue mechanics, and biophysical modeling, all going full throttle to understand the #CF. Still, it took more than 7 years to publish two papers back-to-back (10/12) www.nature.com/articles/s41... www.nature.com/articles/s41...

The @crick.ac.uk is in good hands! Not that it wasn’t before

if you are willing to look clear-eyed at the cumulative evidence, the inescapable conclusion is that our deeply held beliefs about American democracy no longer match our present reality. donmoynihan.substack.com/p/the-author...

CHAOS ERUPTS AT CDC CDC Director Susan Monarez has been ousted after RFK Jr. demanded she change her policy on the COVID vaccine. Top officials from the Vaccine Unit, Zoonotic Division, and the Chief Medical Officer are resigning, per reports. Horrifying news for public health.

Sen Patty Murray (D-WA): “If there are any adults left in the White House, it’s well past time they face reality… We cannot let RFK Jr. burn what’s left of the CDC and our other critical health agencies to the ground—he must be fired.”

Three-Year Funded Postdoctoral Position to study organelle architecture in mammalian oocytes – Terret-Verlhac Lab, CIRB, Collège de France (Starting 2026). For more information, please contact: [email protected]

In Brief: A new center in San Francisco will offer tailor-made CRISPR therapies to cure children with rare diseases www.nature.com/articles/s41...

Just a few more days left to apply!

📅 Apply by Sept 14 to our International Course “Multiscale integration in Biological Systems” in partnership with @normalesup.bsky.social 👉 Open to MSc/PhD students, postdocs & researchers: training.institut-curie.org/courses/mult...

Wow, maybe genomic imprinting as we know it is just the tip of then iceberg. Hopefully this helps usher in a wave of mechanistic studies www.nature.com/articles/s41...

Want to see the impact of #NIH, #NSF and #EPA grant cuts in your community? Check out @noamross.net, @scott-delaney.bsky.social and colleagues' project here. Tell your friends and neighbors about what is happening. grant-witness.us

Well done Katja!

Excited that our paper was published in Science Advances 🧪 Great work by first author Merrick Pierson Smela who will carry this work forward in his new start-up!

Our institution has given a generous donation as well as our fly labs. Convince yours to do so as well!

Congratulations Ohad !

Sign the petition to call for the removal of RFK, Jr. www.standupforscience.net/rfk-impeachm...

Check out this exciting meeting and register! Fantastic line-up of speakers on cell biology of the nucleus and a great venue 🔥

Really beautiful work led by Jessica Leismann in Joan Barau’s lab @imbmainz.bsky.social . If you like elegant mouse genetics, the transposon arms race, and a healthy dose of epigenetics, this one’s for you. www.embopress.org/doi/full/10.... @emboreports.org

WOoo! Hot pre-print alert! 🔥 Check out our new story - We describe evidence that "neuronal oversight" of germline small RNAs prevents sterility and allows lab-domesticated C. elegans to reproduce when temperatures go up (1/2) www.biorxiv.org/content/10.1...

Join us in the #institutcurie exceptional environment to explore the mysteries of X chromosome regulation in early human development

🔴 Day 2 at ASCO Meeting |Attending #ASCO25? Come and meet Institut Curie´s teams! Let’s share insights on our latest clinical research studies and explore new opportunities for collaboration against #cancer 🤝 📍 Institut Curie - Booth 30164 - Hall A

Why do women experience aging-related diseases differently than men? A new study shows that with age, genes on the inactive X chromosome can reactivate – potentially influencing conditions like #dementia and #autoimmunity: go.tum.de/987255 #genetics #aging 📷 @dandergassen.bsky.social

Rencontre avec un académicien – Les cellules sentinelles du système immunitaire : une exploration scientifique Avec Ana-Maria Lennon-Dumenil, immunologiste et biologiste cellulaire. 📍 Institut de France – 23 quai de Conti, Paris 🕕 18h-19h | 🕠 Ouverture des portes à 17h30 🎟️ Inscription requise

Etats-Unis : un chercheur français refoulé pour avoir exprimé « une opinion personnelle sur la politique menée par l’administration Trump »

Soutenue par la Fédération Nationale de la Mutualité Française, l'étude OPTI-DEPIST-MUT est l’une des seules du genre actuellement en cours en France et s’inscrit au cœur de la stratégie décennale de lutte contre le cancer. #Cancerdupoumon Pour en savoir plus : curie.fr/opti-depist-...

Symposium on ‘Enhancer Sequences’ at beautiful @collegedefrance.bsky.social in Paris, by April 11th. Open and free, no registration. Come to relax listening to facts #TherapeuticEffects #VillageGauloix Final programme below. Tell your friends! 🙏🤘

Très honorée d’avoir pu donner, avec Nathan, ce coup d’envoi fictif. Toutes et tous mobilisés contre le cancer avec la jonquille de l’Institut Curie @institutcurie.bsky.social

Inhibition of PRC2 enables self-renewal of blastoid-competent naive pluripotent stem cells from chimpanzee. www.sciencedirect.com/science/arti...

Freezing out the NIH's funding means freezing out American innovation. Research into curing cancer, Alzheimer's, and Parkinson's all delayed. And ultimately it won't just cost us advancements in life-saving research, it will cost us lives.

Stoked to share my research journey next week! I'll walk through my PhD work in the lab of @crougeulle.bsky.social on XIST regulation evolution, and a short preview of my current work with @carldeboer.bsky.social at @sbmeubc.bsky.social at the interface of gene regulation, synthetic biology and ML 🧬

Work led by graduate student @trinitycookis.bsky.social and coauthors Alexandria Lydecker, @paulsauer.bsky.social, and @kasinath-lab.bsky.social is out today where we looked at the inhibition of PRC2 by histone PTMs associated with regions of active transcription. www.nature.com/articles/s41...

The international Curie « Noncoding Genome » course has been revamped! 👉 Dark genome in cell plasticity and heterogeneity. A session on TEs #TEsky with M.E. Torres Padilla, D.Trono and @aktast.bsky.social. Master, PhD and postdoc fellows, a week in Paris during the Spring? Apply before Feb 15th 📌

Uveal Melanoma: Researchers at @institutcurie.bsky.social, led by Dr. Manuel Rodrigues, demonstrate the benefits of using circulating tumor DNA (ctDNA) to monitor metastatic uveal melanoma patients on immunotherapy. Read study published in @naturecomms.bsky.social ▶️ www.nature.com/articles/s41...

Not easy to describe the emotions of seeing our work published in @cellpress.bsky.social ! We explored how novel isoforms emerge during evolution through the exonization of Transposable Elements. Exonized TEs modify the functions and structures of host proteins. www.cell.com/cell/fulltex...

Join us for the Paris-Munich Epigenetics Workshop & Symposium, April 9-11, 2025, Université Paris Cité. The symposium is open for experts and newcomers in the field. Newcomers are encouraged to apply for the one-day WORKSHOP, April 9. See program and registration, free of charge: shorturl.at/mAaWn

Please RS/RT. #GordonConference on "Histone and DNA Modifications" #epigenetics #chromatin 20-25. July 2025. Il Ciocco, Italy. Great speaker lineup. ➡️Register now www.grc.org/histone-and-...

A landscape of X-inactivation during human T cell development www.nature.com/articles/s41...

Enjoy!

🇫🇷Vous faites de la recherche et souhaitez partager votre passion pour la science avec des lyceens? Inscrivez vous a Déclics! Je cherche encore quelques scientifiques pour participer a une visite le 9 decembre. Rejoignez nous! www.cerclefser.org/fr/declics/j...