Nicolas Robine 🇪🇺🇫🇷🇺🇸
@nicorobine.bsky.social
📤 4273
📥 1158
📝 1308
Artisanal Genomics since 2002. Mostly in English, sometimes in French.
#NoPasaran
reposted by
Nicolas Robine 🇪🇺🇫🇷🇺🇸
Linda Kachuri
about 12 hours ago
📢
#TOPMed
e/sQTL atlas is out in
@science.org
today! Happy to contribute to this amazing team effort and rich resource for the genomics community: 69k cis-eQTL + 35k cis-sQTL across 6 tissues/cell types and diverse ancestries. Still more to discover 😉🧬
www.science.org/doi/10.1126/...
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Cross-cohort analysis of expression and splicing quantitative trait loci in TOPMed
Most genetic variants associated with complex traits are hypothesized to regulate gene expression. To understand the genetics underlying gene expression variability, we characterized 14,324 RNA-sequen...
https://www.science.org/doi/10.1126/science.adx2989
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Cancer disparities researchers say federal funding changes have disrupted their work
www.npr.org/2026/07/15/n...
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Cancer disparities researchers say federal funding changes have disrupted their work
In a survey, 93% of cancer researchers who study disparities said federal policy changes have affected them. Funding is harder to come by and they worry it's slowing progress in their field.
https://www.npr.org/2026/07/15/nx-s1-5893653/cancer-disparities-gaps-research-funding-grant-disruptions
about 17 hours ago
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what it looks like when an author has 7+ affiliations listed on the paper... (images from
www.reddit.com/r/ussr/comme...
)
about 20 hours ago
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2 days ago
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Is it too late to boycott this World Cup? 🇫🇷🇪🇸
3 days ago
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reposted by
Nicolas Robine 🇪🇺🇫🇷🇺🇸
Paul Francois
3 days ago
New paper 🧵 What if the "landscape" that guides cell differentiation isn't fixed, but is sculpted, in real time, by the very cells moving through it? We call this a 'sandscape' : grains of sand that carve dunes as they move, while the dunes' shape simultaneously steers where the grains go next.
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Argentinian inflation: every soccer game is now 120 minutes…
#ARGSUI
5 days ago
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[life of an Academic editor]: after 99 days and 14 declined or ignored invitations to review a manuscript, finally, FINALLY, one accepted. Just need to find another one and this paper will be reviewed. Keep the faith, authors...
7 days ago
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I already forgot the name of the player who wasn’t supposed to play this game…
#USABEL
10 days ago
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Belgium’s never been that good in years! Just wonder what put them in this state of mind 🤔 🇺🇸-🇧🇪
10 days ago
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reposted by
Nicolas Robine 🇪🇺🇫🇷🇺🇸
Alex Rubinsteyn
about 1 month ago
Wonderful deep-dive into the always compelling, always confusing world of therapeutic cancer vaccines by
@owlposting1.bsky.social
: "How to build a cancer vaccine, and whether they will work this time"
www.owlposting.com/p/how-to-bui...
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How to build a cancer vaccine, and whether they will work this time
8.4k words, 38 minutes reading time
https://www.owlposting.com/p/how-to-build-a-cancer-vaccine-and
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Found a company selling "whole genome sequencing - 30X" for any species, human or pet (
www.the-odin.com/whole-genome...
). Also, I am now very tempted to adopt an Australian lungfish as a pet.
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Whole Genome Sequencing (30x) — Human & Any Organism
Sequence your complete genome at 30x coverage for $599. FASTQ, BAM & VCF included. Illumina PE150. Humans + any organism with a reference genome. 2–3 weeks.
https://www.the-odin.com/whole-genome-sequencing-30x/
13 days ago
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Cesaria Evora’s Saudade, obviously…
#ARGCBV
www.youtube.com/watch?v=xBpU...
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Sodade
YouTube video by Cesaria Evora - Topic
https://www.youtube.com/watch?v=xBpUo-VHXHQ
13 days ago
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reposted by
Nicolas Robine 🇪🇺🇫🇷🇺🇸
grimmrad 🧬🎼🖼️🏛️
17 days ago
New review in Nature Reviews Cancer: "Imaging the hallmarks of cancer." A collaborative effort to map non-invasive clinically relevant in vivo imaging onto every cancer hallmark, separating what can be seen directly from what is only accessible via surrogates. 🧵
doi.org/10.1038/s415...
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Imaging the hallmarks of cancer - Nature Reviews Cancer
In this Review, Grimm et al. describe the range of non-invasive diagnostic imaging approaches to monitor the various hallmarks of cancer and how their implementation is shaping clinical practice.
https://doi.org/10.1038/s41568-026-00950-y
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1. PSG ⚽️ 2. Knicks 🏀 3. France ⚽️ ?
about 1 month ago
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Starting now:
satijalab.org/scgd26/
www.youtube.com/watch?v=ynO1...
add a skeleton here at some point
about 1 month ago
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reposted by
Nicolas Robine 🇪🇺🇫🇷🇺🇸
Federico Gaiti
about 1 month ago
Happy to share our new review in Blood, led by Jiaoyi Chen & Benson Wu! We explore how DNA methylation can help retrace a cancer’s history and reveal how tumours evolve and respond to treatment.
www.sciencedirect.com/science/arti...
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My son will be mad tomorrow morning
about 1 month ago
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WHAT A GAME!!! Let’s go Knicks!!!
about 1 month ago
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[fr] Prévoir des collisions de voiliers cet été entre les utilisateurs de Claude et de Gemini! Claude à gauche, Gemini à droite (c’est Gemini qui a raison)
about 1 month ago
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about 1 month ago
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reposted by
Nicolas Robine 🇪🇺🇫🇷🇺🇸
eric lai
about 1 month ago
one of the best things about being a mentor is seeing trainees go on to amazing things on their own. just spent some time with former lab superstars Nicolas
@nicorobine.bsky.social
(Director Computational Biology
@nygenome.org
) and Peter
@psmibert.bsky.social
(VP Biology
@10xgenomics.bsky.social
)!
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⭐️⭐️
about 2 months ago
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Single Cell Genomics Day: A (Virtual) Practical Workshop. June 12, 2026, organized by
@nygenome.org
's Rahul Satija Free, livestreamed, no registration.
about 2 months ago
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[fr] Je pense que ce traducteur de l’anglais (Américain) n’a jamais foutu les pieds dans un MacDo (in Le Maître des Illusions (The Secret History). Donna Tart 1993)
about 2 months ago
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A multi-agent system for automating scientific discovery
www.nature.com/articles/s41...
An AI system to help scientists write expert-level empirical software
www.nature.com/articles/s41...
Accelerating scientific discovery with Co-Scientist
www.nature.com/articles/s41...
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A multi-agent system for automating scientific discovery - Nature
Nature - A multi-agent system for automating scientific discovery
https://www.nature.com/articles/s41586-026-10652-y
about 2 months ago
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reposted by
Nicolas Robine 🇪🇺🇫🇷🇺🇸
Stephen Turner
about 2 months ago
Accelerating scientific discovery with Co-Scientist:
www.nature.com/articles/s41...
rdcu.be/fjE3k
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I don’t know the details of that particular story and it sounds amazing. But WHY are we giving all the credits to « AI » when it’s the results of a ton of people’s great work (to set up the program, run sequencing and bioinformatics analyses, multi-disciplinary medical boards, etc)?
add a skeleton here at some point
about 2 months ago
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reposted by
Nicolas Robine 🇪🇺🇫🇷🇺🇸
Alexis Verger 🧬🧫🧪
2 months ago
#RIP
Pierre Chambon (1931-2026) via
@alainberetz.bsky.social
one of the last giants in biology: PARP, nuclear receptors, RNA Pol II, nucleosome, promoters, split genes
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⚠️Preprint alert⚠️: we set up Polyethnic-1000 at
@nygenome.org
to study the molecular basis of cancer disparities. One striking example is endometrial cancer, with much higher mortality in patients of African ancestry.
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2 months ago
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[fr] SciencesPo, ENS, HEC
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3 months ago
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Front row seat at Carnegie Hall with
@grimmrad.bsky.social
3 months ago
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reposted by
Nicolas Robine 🇪🇺🇫🇷🇺🇸
eric lai
3 months ago
of many projects Craig Venter led, of personal significance was the fly genome, a unique and i think unexpected collaboration of his company Celera Genomics and the BDGP, led by my pd advisor Gerry Rubin. the power of a shotgun sequenced metazoan, benchmarked to a physical map, transformed genomics.
add a skeleton here at some point
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reposted by
Nicolas Robine 🇪🇺🇫🇷🇺🇸
The New York Times
3 months ago
J. Craig Venter, a scientist and entrepreneur who decoded the human genome, has died at 79.
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J. Craig Venter, Scientist Who Decoded the Human Genome, Dies at 79
A risk-taking outsider, he brought speed, competition and controversy to one of science’s biggest races.
https://nyti.ms/49hkzRS
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reposted by
Nicolas Robine 🇪🇺🇫🇷🇺🇸
Dora Koller
3 months ago
Our new paper, led by
@renatopolimanti.bsky.social
and I, and published today in Nature Genetics, is the largest multi-ancestry GWAS of endometriosis to date including 1.4 million women, 105,869 cases, six global ancestry groups. Previous studies were almost exclusively European.
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reposted by
Nicolas Robine 🇪🇺🇫🇷🇺🇸
Peter Kraft
3 months ago
Getting “us” to Mars.
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I have an adult kid…
3 months ago
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reposted by
Nicolas Robine 🇪🇺🇫🇷🇺🇸
Katie Mack
3 months ago
When Einstein developed general relativity the closest thing to a practical application that could even be imagined at the time was a slightly more precise description of where to look for the planet Mercury in the sky, and yet now we’d all be literally lost without it. Anyway: fund basic research.
add a skeleton here at some point
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reposted by
Nicolas Robine 🇪🇺🇫🇷🇺🇸
Pierre Kerner
3 months ago
For me, it was the fact that I misred and misunderstood this ad...
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reposted by
Nicolas Robine 🇪🇺🇫🇷🇺🇸
3 months ago
Very interesting read.
www.asimov.press/p/bioinforma...
(Thanks to
@torstenseemann.bsky.social
for sharing over on the
#ABACBS
slack)
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A Brief History of Bioinformatics Software
How computer scientists on the fringes of biology made sense of sequencing data.
https://www.asimov.press/p/bioinformatics
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reposted by
Nicolas Robine 🇪🇺🇫🇷🇺🇸
Roxanne Khamsi
3 months ago
📖 My book BEYOND INHERITANCE is out today.
tinyurl.com/5yjsr97n
This journey started with a fact I couldn’t ignore: Even in otherwise healthy adults, mutant cells can appear in the blood—quietly doubling the risk of heart disease and stroke.
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reposted by
Nicolas Robine 🇪🇺🇫🇷🇺🇸
Fulcrum Genomics
3 months ago
Deep QC should run on every sequencing dataset. In a new post, Fulcrum co-founder
@tfenne.bsky.social
explains why he built Riker, a modern successor to Picard designed to make rich sequencing QC fast enough to run every time. Blog:
shorturl.at/oUTXk
Repo:
github.com/fulcrumgenom...
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🤮🤮🤮
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3 months ago
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Think about it next time you fill your disclosure of conflict of interests for papers/grants/talks etc.
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3 months ago
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Here it is: Atera: « High throughput. Whole transcriptome. Single cell sensitivity. »
pages.10xgenomics.com/wbr-2026-02-...
Thoughts?
add a skeleton here at some point
3 months ago
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reposted by
Nicolas Robine 🇪🇺🇫🇷🇺🇸
Nuria Lopez-Bigas
3 months ago
Tumor promotion through the lens of evolution This review grew out of many long conversations, shared ideas, and lively discussions It has been a real pleasure to think together with Allan, Paul, Eve, and Abel about how tumours develop and how carcinogens shape cancer risk
rdcu.be/fdC2J
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Tumour promotion through the lens of evolution
Nature - This Review revisits tumour initiation and promotion in light of clonal diversity and the presence of cancer driver mutations in normal tissues, aiming to understand mechanisms that enable...
https://rdcu.be/fdC2J
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reposted by
Nicolas Robine 🇪🇺🇫🇷🇺🇸
Thiago Carvalho
3 months ago
'Our results support the hypothesis that somatic mutations in autoimmune lymphocytes may allow them to escape tolerance constraints through a polyclonal cascade of somatic evolution, providing new insights into the molecular basis of autoimmune disease.'
www.nature.com/articles/s41...
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Polyclonal selection of immune checkpoint mutations in thyroid autoimmunity - Nature
Nature - Polyclonal selection of immune checkpoint mutations in thyroid autoimmunity
https://www.nature.com/articles/s41586-026-10493-9
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THE HUMAN MOSAIC Why to live is to mutate. By Jerome Groopman.
www.newyorker.com/magazine/202...
A review of Roxanne Khamsi « Beyond Inheritance »
www.penguinrandomhouse.com/books/711682...
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We Are All Constantly Mutating—and That’s a Good Thing
Genetic research has been complicating the idea of the genome as a determinative blueprint.
https://www.newyorker.com/magazine/2026/04/13/beyond-inheritance-roxanne-khamsi-book-review
3 months ago
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reposted by
Nicolas Robine 🇪🇺🇫🇷🇺🇸
Scott Horton
3 months ago
Jack Szostak "All of these things frighten me, and they should frighten you as well. I made the decision to create a life for myself here, because I viewed this as a place that rewarded determination, hard work, and integrity. It still has a chance to be that place again."
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I’m a Nobel Prize-winning immigrant. I can no longer recognize this country.
Attacks on science and immigrants are destroying America.
https://open.substack.com/pub/ofthebrave/p/im-a-nobel-prize-winning-immigrant?utm_campaign=post-expanded-share&utm_medium=web
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Maybe it takes them forever to get out of the capsule because they actually look like this:
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3 months ago
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