New case study out: Fulcrum Genomics + Belay Diagnostics. We helped take an ECS pipeline from prototype → CAP/CLIA-ready clinical deployment, with auditability, testing to prevent regressions & cloud architecture fixes that reduced cost + avoided resource exhaustion. 👉 tinyurl.com/mtkwup9b

ICYMI: Last week we announced MutSeqR, an open-source R package for error-corrected sequencing analysis, co-authored by our own Clint Valentine with Health Canada and U Ottawa. It brings much-needed standardization to genetic toxicology research. 🧬 🖥️ blog.fulcrumgenomics.com/p/mutseqr-op...

Today we feature a teammate whose way of thinking connects games and science. It’s that mix of strategy and lightness that makes working with him such a pleasure. By the end we hope you’ll feel like you’ve met us — or want to. Meet Zach Norgaard: blog.fulcrumgenomics.com/p/meet-zach-...

10th Anniversary Core Values blog series: Valuing People Valuing People is one of our deepest commitments: to ourselves, to our team, and to our clients. Life is messy—just like biology. When life gets complicated, we don’t look away. We step in. Read More: blog.fulcrumgenomics.com/p/core-value...

Just released Sassy 0.1.4, which now supports macos/arm NEON instructions :) Also some smaller fixes by @tfenne.bsky.social. github.com/RagnarGrootK...

We love working with people who notice how things fit together, who make unwieldy problems work better. The 'Meet the Team' series spotlights humans behind our bioinformatics work. We hope you'll feel like you've met us — or want to. Meet Erin McAuley: blog.fulcrumgenomics.com/p/meet-erin-...

We’re lucky to work with people who are not just skilled, but thoughtful, curious, and quietly surprising. This series of short interviews offers a window into who we are. By the end, we hope you’ll feel like you’ve met us — or want to. Meet Ted Brookings: blog.fulcrumgenomics.com/p/meet-ted-b...

Never change, Penzeys

I have the power?

We believe in leaving things in a better state than we find them. Founding Partner @tfenne.bsky.social shares how our team contributes back to the open source ecosystem, strengthening the foundations on which many scientific and technical projects are built. blog.fulcrumgenomics.com/p/recent-ope...

Our people are our greatest asset — sharp, thoughtful, and pretty fun to get to know. We have short interviews on our blog to offer a view of each of our colleagues. By the end, we hope you’ll feel like you’ve met us — or want to. Please meet Jason Fan: blog.fulcrumgenomics.com/p/meet-jason...

Nice blog post by @charlottetolonen.bsky.social from a couple of weeks ago about how to use conda for #bioinformatics without running afoul of anaconda licensing: blog.fulcrumgenomics.com/p/anaconda-l... 🧬 🖥️

PhD Timeline xkcd.com/3081

Welcome to all our new followers! 💚

We expected 2,000 people out in GOP-held Greeley, Colorado. 11,000 people showed up. Something special is happening, folks. Now is the time to organize in every dimension possible and get to work.

The only fair way to handle this is to appoint a team of teenagers to tear this company limb from limb until we find out what kind of financial damage they are hiding and where

fqgrep release 1.1.0 now speeds up searching FASTQ files! Thank-you to both Markus Schlegel from @activegroupgmbh.bsky.social for updating seq_io and Nicholas D. Crosbie of grepq for some competition and inspiration. See more: github.com/fulcrumgenom...

KEEP CALLING. PEEL OFF ALL DEM SENATORS YOU CAN. ☎️: (202) 224-3121 Tell them to vote NO on Cloture and NO on CR. Vote is pushed to after 1:15ish for now. Situation is fluid. The only public YES votes are Schumer and Fetterman. They need 7-8 total. KEEP CALLING. Call retiring Senators too!

SOTU seats are not assigned. There are general seating areas for each body (House, Senate, SCOTUS,etc) but there are honored seats for each party’s leadership and they’re even trying to squat those. If it doesn’t sort out, be aware you may see applause on both sides of the aisle but they may be GOP

This is Marco Rubio explaining how the USA promised to defend Ukraine forever if they got rid of their nuclear arsenal left after the Soviet Union fell. This is why lil marco was sinking into the couch. He was hoping we wouldn’t find it…so don’t RT right now this very second.

RNA xkcd.com/3056

Since Trump has claimed Elon doesn’t run DOGE, we wanted to make sure you know who is running our government. This list has been updated with 15 names.

Excited to be headed to AGBT later this month, and looking forward to reconnecting with all the people I haven't seen in person in years!

It would be fantastic if major federal institutions would acknowledge that the executive branch cannot legally unilaterally cancel or redistribute congressionally appropriated funding on ideological grounds and thus they have no legal obligation to comply with such directives

Why @americanexpress.bsky.social, do I have to pick up a phone, get bounced around hold menus and CSRs, and then listen to someone recite the benefits of my card ... just to close the account?!

If Trump doesn't reverse course, millions could lose healthcare, food assistance, childcare, and even emergency services. We've heard reports of Medicaid portals being shut down and childcare funds being frozen. Trump is steering the US into a disaster of his own making.

Donald Trump gave us a bunch of broken promises—oh, sorry, I mean lies—and now we’re all stuck paying for it. Rule of law is being TRAMPLED, families are being TORN APART, and it's only been a WEEK. Is there a grade lower than an F?

Is the "temporary pause" of disbursement of all federal grants/loans an unlawful impoundment? It almost certainly is. A brief 🧵

Pete Hegseth’s confirmation will make our nation less safe. It is a sad and dangerous day when Republican Senators put loyalty to President Trump ahead of our national security.

Can't wait to hear more about this at AGBT!

Do you ever use the noodles crate in Rust? If not, you should consider it. Look at this developer responsiveness! Bug report, to fix, to new version published in the matter of an hour. You can't even pay for service this good!

Why did Trump declare a national energy emergency? Simply put, Trump’s declaration aims to accelerate fossil fuel projects on public lands and roll back environmental protections.

BWA python bindings are here. #bioinformatics #genomics pybwa.readthedocs.io/en/stable/ap...

It’s Appa!

I want to watch TV coverage of the live fall of the Syrian regime. CNN is airing a Giuliani documentary, Fox News has a comedian joking about Canada, MSNBC a documentary about migrants So I turned on BBC,which is breathlessly switching between Syria, South Korea demonstrations, and Ghana election

I'm looking for an Evil BAM file. By Evil, I mean all the weird cases every bioinformatician has seen at some point and gone "Oh $*%!, I forgot to handle that case in my code!" If this doesn't exist then we should make it happen. Really needed for testing genomics tools.

Interested in doing a PhD with me in Sweden? Experimental+computational genomics skills and/or interests? We have an open position! Great environment at KTH on @SciLifeLab campus, staff benefits, well-funded project, close interactions with our New York team. kth.varbi.com/en/what:job/...

Dear Apple: I don't think we have the same definition of "Always"

bioRxiv goes big on Bluesky: accounts for all subject categories now available (Please Reskeet) connect.biorxiv.org/news/2023/09...

I posted two identical job openings on Twitter and BSky: Twitter: 78 RTs, 47 likes BSky: 34 reposts, 22 likes. More engagement on Twitter, but the difference is not that big. I expect that by the end of the year, BSky will overtake Twitter as the preferred social media platform for academics.

Noticing a lot more genomics and bioinformatics peeps on here recently; welcome! I'm still not seeing a ton of genomics/bioinfo "content", so if there's a curated feed you use please share :).