Also last week: our first review led by @jackpcw.bsky.social Cis-regulatory strategies in developmental patterning We discuss how cells choose their fate either changing their regulatory landscape or using the same elements without accessibility changes. authors.elsevier.com/sd/article/S...

Very excited to share the first preprint from the lab: www.biorxiv.org/cgi/content/... We investigated neural crest migration all the way from head to tail of the Zebrafish embryo and we found their nuclei suffer dramatic deformations. Want to know of they cope with feeling squeezed? 🐟🐠🐟

Research from Professor Francesca Spagnoli reveals how different cell types develop, assemble, and communicate to build a functioning pancreas.🧬 www.kcl.ac.uk/news/researc... Image credit: Alejo Torres-Cano et al. Sci. Adv. 11,eadx5791(2025). DOI: 10.1126/sciadv.adx5791

v sad to hear Antonio García-Bellido's passing. his work on mitotic clones led to fundamental insights such as compartment boundaries, enabled post-embryonic analysis of lethals, and revealed autonomous vs non-autonomous effects of mutants. and founding father of Spanish DB and Drosophila schools.🪰

Thrilled to share my main postdoc work with @jamesbriscoe.bsky.social We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions 🧵👇 www.biorxiv.org/content/10.1...

Out @natcomms.nature.com: our work on how the ❤️-supporting pericardium forms & acts in pediatric heart conditions.🎈🫀 Expanding our preprint & with our first HCR (thx to @thelovelylab.bsky.social!). Congrats all! #devbio #zebrafish #CHD @cupediatrics.bsky.social @cudevbio.bsky.social rdcu.be/eIJm5

🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x

Thrilled to share the first story from my postdoc! 🎉 A wonderful experiment + simulations collaboration. In the Drosophila wing, we find that 3D cell shapes affect signalling range and fine-tune developmental patterning www.biorxiv.org/content/10.1... Thread below ⬇️

Excited to share our latest work with @jamesbriscoe.bsky.social . A global #cis-regulatory temporal program guides how spatial cues are interpreted in neural progenitors. We show how #space and #time can be integrated to generate cell type diversity in the #spinalcord. Congrats to all authors.

This isn't a coincidence, IMO. The fly community is generally super rigorous - because there are so many tools and techniques available, people expect you to really nail things in order to get published (and keep getting funded)

[0/8] Stoked to share our work with @arjunraj.bsky.social on tissue organization in the gastruloid. We use lineage tracing and spatial transcriptomics to show that diversity among stem cell clones promotes, rather than hinders, gastruloid development: www.biorxiv.org/content/10.1...

Interested in developmental epigenetics? So are we! Apply now to join us for your postdoc! Multiple positions across multiple groups @mrc-lms.bsky.social Projects spanning germline demethylation, gene regulation, genome architecture in development & disease 👇👇 lms.mrc.ac.uk/work/vacanci...

We've just been awarded a grant to study the cellular basis of regeneration – to track the progenitors of sensory organs in the context of leg regeneration, in our favourite crustacean tinyurl.com/parhyale, based on live imaging and cell tracking. The project involves some cool collaborations... 1/3

Want to hear more about bioimaging and image analysis at UCL? Follow @biig-ucl.bsky.social This is a wonderful community for those bioimaging enthusiasts!

Embryonic CX3CR1+ cells constitute a multipotent epiblast-derived progenitor population that contributes not only to the formation of tissue-resident macrophages, but also of cardiomyocytes and heart endothelial cells Young-sup Yoon and coworkers www.embopress.org/doi/full/10....

Issue 12: Commentary: in vivo metabolomics in the cancer clinic Review: oxygen-sulfur interdependence ADP-ribosylation in M.tuberculosis Microprotein promoting BAT thermogenesis Cover by @kenzoivanovitch.bsky.social and colleagues www.embopress.org/toc/14602075...

Save the date! March 23-26 will be the dates for our 2026 @bsdb.bsky.social annual meeting: Molecules to Morphogenesis! Excited to reveal more details soon! Want to attend with a reduced rate, and have access to conference/travel grants for other meetings too? Don't forget to join the BSDB :)

Very happy to share I've written a review on placental vascular formation in mice and humans, now published in @dev-journal.bsky.social. journals.biologists.com/dev/article/... @idrm.ox.ac.uk Funded by the @thebhf.bsky.social

Beautiful work from @sagnera.bsky.social & co on how spinal neurons diversify A temporal TF clock in spinal neurons, sequentially specifying different motor and sensory neuron subtypes during development A shared molecular timer driving cellular diversity www.biorxiv.org/cgi/content/...

congratulations! @shayma-a.bsky.social @yen-network.bsky.social

Not first time thank you: pubmed.ncbi.nlm.nih.gov/36736300/

Researchers @uclpophealthsci.bsky.social and @crick.ac.uk, led by Dr @kenzoivanovitch.bsky.social & Shayma Abukar, have, for the first time, identified the origin of cardiac cells using 3D images of a heart forming in real-time, inside a living mouse embryo www.ucl.ac.uk/news/2025/ma...

We’re excited to share the first publication from our lab, now out in @EMBOPress! @shayma-a.bsky.social @ucl.ac.uk Using live imaging in the mouse embryo, we tracked how heart progenitors migrate and assemble into the heart tube.

Fresh from the press! @lankylaste.bsky.social, @guijacquemet.bsky.social and I put together a practical guide on how to develop software for life science applications.

We’re hiring a new research fellow. Come join us in London to study glial cells in the ageing retina using killifish as a model. www.ucl.ac.uk/work-at-ucl/...

In Praise of Peer Review As an Editor of the journal Development, I often hear complaints about peer review. We all know the problems - from lengthy review times to requests for seemingly unnecessary experiments. I agree with many of these complaints. Katherine Brown (Executive Editor of…

New @dev-journal.bsky.social editorial We know we have high standards - but we're committed to making publishing with us constructive From clear revision guidance to limitations sections & transparent peer review, we're here to help you share your science journals.biologists.com/dev/article/...

Using #gastruloids F. Lescroart and colleagues explore the origins of the most complex organ in our body, the #heart. Very good start of unravelling an amazing process in which an organ is being designed and redesigned at the same time it functions www.nature.com/articles/s41...

We would like to share an update of our live analysis of heart development in mouse embryos! @shayma-a.bsky.social @jamesbriscoe.bsky.social www.biorxiv.org/content/10.1...

Second (BBSRC Yorkshire Bioscience DTP-funded) PhD project available in our lab (jointly with @christoseland.bsky.social) examining how biomechanical cues crosstalk with signals to influence cell fate decisions during hESC differentiation. More details here: thenode.biologists.com/jobs/funded-...

7 fully funded PhD scholarships for Black, Asian students at the start of their academic career. search.app?link=https%3...

Our interdisciplinary MRes is recruiting students for Sept 2025 entry : www.ucl.ac.uk/lifesciences...

Can I ask you to share a PhD advert at Bristol Uni please? Rhomboid proteases play a role in neurons that is essential for life- but it is not characterised. Got a student interested in cell biology, electrophysiology and neurobiology? Send them our way! tinyurl.com/56f24f7c

It was nice writing this piece and thinking about ichthyosporeans to distract myself from the absurdity of the world over the past weeks. With perfect comedic (or tragic) timing, it came out today. Check it out if you need a distraction from the absurdity of the world. www.nature.com/articles/d41...