I am very happy (and a bit scared) to present to you what we have been working on over the last 4 years. This manuscript is exactly what I dreamt of when I started the lab and I could not be happier and prouder of the outcome!

Don't forget to register for our upcoming Spring Meeting: 'Molecules to Morphogenesis' Get your abstracts submitted by the 16th of January! bsdb.org/meetings

Excited to share @rbrianroome.bsky.social ‘s beautiful paper on development of the dorsal horn of the mouse spinal cord @science.org This is how the anatomical organization and cell types that process pain, touch, body position and more are laid down. www.science.org/doi/10.1126/...

Good to see the peer reviewed version of this published A chemo-optogenetic system for spatiotemporal control of gene expression We use it to: - Reconstruct SHH mediated neural tube patterning in vitro - Measure extracellular half-life of Shh www.cell.com/developmenta...

Ten days left to apply to be a @crick.ac.uk Early Career Group Leader Closing date 27th November www.crick.ac.uk/careers-stud...

How do pleiotropic TFs generate organized diversity in developing tissues? @spinalorga.bsky.social shows that PAX3 & PAX7 organize #SpinalCord by acting as both repressors & pioneer activators, regulated by #morphogens to ensure precise neural subtype specification @plosbiology.org 🧪 plos.io/4qumsla

Our latest: *Hierarchical lineage architecture of human and avian spinal cord revealed by single-cell genomic barcoding* For a summary & the digested highlights see thread🧵 from @giulia-boezio.bsky.social www.biorxiv.org/content/10.1...

Are you enthusiastic about stem cell biology and developmental biology and looking to start a PhD in 2026? Funded opportunites now available. Contact for more infomation. Links below! @lovegrovelab.bsky.social @veronicabiga.bsky.social @manchester.ac.uk @ukri.org

Just published: The cis-regulatory logic integrating spatial and temporal patterning in the vertebrate neural tube A global temporal chromatin program, operating across the CNS, directs binding of specific spatial TFs & hence when/where neurons & glia are born authors.elsevier.com/sd/article/S...

Our latest "Dynamic Landscape Analysis of Cell Fate Decisions: Predictive Models of Neural Development From Single-Cell Data" A rigorous mathematical foundation for Waddington's landscape to study cell fate decision making Applied to ventral neural tube development www.biorxiv.org/content/10.1...

First preprint from the lab! Expression of 3 TFs - Onecut2, Pou2f2 and Pou3f1 - in sequentially generated neurons correlates with and is functionally required for the correct specification of neuronal subtypes mediating spinal sensory and motor output! www.biorxiv.org/content/10.1...

Beautiful work from @sagnera.bsky.social & co on how spinal neurons diversify A temporal TF clock in spinal neurons, sequentially specifying different motor and sensory neuron subtypes during development A shared molecular timer driving cellular diversity www.biorxiv.org/cgi/content/...