Excited for our next special issue and looking forward to working with Abby Buchwalter (@abbybuch.bsky.social) and Megan King (@luskinglab.bsky.social)! Working on the cell biology of the nucleus? Send your papers our way! #notforprofit

Phantastic review of SPT method and analysis. Great resource for every single molecule tracking enthusiast! Congratulations, @gebhardtlab.bsky.social

Yesterday we had the School of Medicine and Population Health PGR symposium - a fantastic range of talks and posters from our students! We had excellent career sessions from Faith Nutter Howard David King and Amy Turner Thanks to our ECRs who gave a useful and honest take on finishing a PhD.

Announcing a new @embo.org Workshop on "Intracellular mechanics and organelle mechanobiology" that we are organizing with Michael Krieg and Verena Ruprecht at @icfo.eu (Barcelona) on 16-20 February, 2026. Please, repost and spread the word! 🙏 #EMBOmechanobio meetings.embo.org/event/26-org...

Doubling up on the measurements and toys today - so great and useful to have this kit next door to each other!

Postdoc positions open in my lab (Francis Crick Institute) to study 1. initiation of DNA replication. 2. chromatin replication/epigenetic inheritance. Great for biochemists, biophysicists and cryo-EM/cryo-tomography scientists. Deadline 3 August 2025. crick.wd3.myworkdayjobs.com/External/job...

This is a piece that I and @karsten-rippe.bsky.social discussing a lot, and a topic that is very close to my heart. The editors @naturerevgenet.bsky.social gave us the stage to do so, and the final version of our review is now available under this link: rdcu.be/erP1u A short thread follows 1/n

The QS World University Rankings 2026 have just been released and we’ve placed 92nd within the World Top 100! Huge congratulations and thanks to everyone in the University of Sheffield community for this achievement; from staff and students to alumni, supporters and friends around the world!

🚀 Manual mask annotation slowing you down? 💡 SAMJ is a new ImageJ/Fiji plugin using Segment Anything (SAM) for fast, interactive segmentation — no GPU needed, one-click install, real-time results. 🔬 Perfect for large biomedical images. arxiv.org/abs/2506.02783 #AI #Bioimaging #ImageJ #OpenSource

If heterochromatin is really a liquid-like condensate, why is it not spherical? We investigated whether mechanical interactions between a condensate and a fiber network can explain the variety of morphologies seen in phase-separated nuclear compartments www.biorxiv.org/content/10.1...

Back again!

Applications are now open for the 4th edition of the “Ecole de Physique des Houches” on Fluorescence Markers for Advanced Microscopies, a WE-Heraeus seminar. March 15th-20th 2026 Join us to learn everything you wanted to know about Fluorescent Markers for advanced microscopies.

Back in Harwell again for a late night reagent drop!

Quick visit back to Sheffield for more samples complete!

Back in the lab’s second home for two weeks!

Thank you for all the donations! This reel sums up the walk! www.instagram.com/reel/DJSC8HL...

Final week of fundraising- thanks for all the donations- an amazing amount has already been given! www.justgiving.com/team/thalia

Thank you for all the donations! It makes a massive difference to the charity and families! . www.justgiving.com/team/thalia

Less than two weeks to go! Thanks for all the donations! www.justgiving.com/team/thalia

Fantastic coverage from BBC Look North! . www.bbc.co.uk/programmes/b...

Early start media day! So proud to talk about Thalia…Morning radio then BBC Look North later . #cancer #braintumours #childhoodcancer

Here we share our opinions on "Practical considerations for data exploration in quantitative cell biology" journals.biologists.com/jcs/article/... Joanna, Hanna and I worked quite a bit on this piece and I hope you find it useful Many thanks to @jcellsci.bsky.social for publishing it

Day in the life of an academic - smFRET onto Lattice light sheet then delivering an afternoon workshop

Some great talks coming up this morning!

We are walking the Ullswater Way with OSCAR's Paediatric Brain Tumour Charity in May. Learn more and donate here: www.justgiving.com/team/thalia #braintumours #childhoodcancer #cancer

Like plucking a tiny guitar string!

How can we hope for things to improve when I send @braintumourrsch.bsky.social letter to our MP @JakeBenRichards then get a reply about Pancreatic cancer! Not good enough!

The Rare Cancers Bill is a major milestone! We've joined forces with rare cancer charities to push for this game-changing legislation, bringing hope for better research and treatments. bit.ly/4kHEOfD #RareCancersBill

Just out from @kazu-maeshima.bsky.social www.biorxiv.org/content/10.1...

We are so proud of how Thalia has handled the past two years and continues to approach every day! Brain tumours are devastating and we desperately need more treatments to provide options for families!

Are PhDs losing their lustre? Why fewer students are enrolling in doctoral degrees www.nature.com/articles/d41...

Fantastic few days on a grant panel in Poland - fantastic level of science and nice to explore Krakow!

🔎 Looking to start a PhD in Sept 2025? The Crick Institute spring round for PhD recruitment is open! If you are interested in actin cytoskeleton and imaging 🔬 then check out my project on role of Arp2/3 iso-complexes in regulating invadopodia👇please RT www.crick.ac.uk/careers-stud...

Currently in Krakow for a grant panel……only one news story here!

Can you explain your doctoral research through interpretive dance? The 17th annual #DanceYourPhD competition is open! Submit by 28 March for a chance to win $2000: https://scim.ag/4gKMnz9

In their #OpenAccess Review, Marta Gawor, @christoseland.bsky.social and colleagues discuss how nuclear myosins and actin regulate nuclear architecture and mechanics. journals.biologists.com/jcs/article/...

There is plenty to complain about in UK HE at the moment but a lot of the environment and atmosphere can be raised by academics supporting each other…that is within our power…it is a choice not to bother!

Excited to share the first paper from my lab 🤩 - a great collaboration with Dani Fachinetti lab - we discover a #mechanosensitive nuclear envelope #checkpoint that arrests cells directly post chromosome mis-segregation rdcu.be/d5AC9 👇🧵 #cancer #mechanics #p53 #chromatin

Only a few days left to apply for our BBSRC-funded PhD project with @christoseland.bsky.social aiming to understand how biomechanical cues crosstalk with extrinsic signals to influence cell fate decisions during hESC/NMP differentiation. Please RT! www.findaphd.com/phds/project...

Merry Christmas!

Very happy to see our study "printed" www.science.org/doi/10.1126/.... We report how mechanics are related with DNA recombination efficiency. Great work by Kate @cmcb-tud.bsky.social @tudresden.bsky.social in collab with @celineloot.bsky.social and @amazeld.bsky.social @pasteur.fr . Synopsis 👇1/4

We've been awarded a UKRI MRC grant to examine the causes and consequences of #heterochromatin hypomethylation in cancer 🥳. #postdoc opportunity coming in the near future. #epigenetics. Please share with anyone who might be interested.

First time back at the Christmas markets in 10 years!

Playing with condensates on the AFM

📢 Make your work FASTER and EASIER! Use AlphaBridge to analyze your AlphaFold results and receive a clear, easy-to-understand output—even for non-experts. ➡️ Let AlphaBridge help you accelerate your workflow! ❤️ Share and try it here: alpha-bridge.eu 👀Read more: www.biorxiv.org/content/10.1...

We are seeking a motivated postdoc to join our lab!  Our research focuses on live-cell imaging/analysis to reveal how chromatin behaves in living cells and how its behavior contributes to cellular functions. www.nature.com/articles/s41... www.science.org/doi/10.1126/... Interested? Please DM me!

This looks awesome 🌟😎

Fantastic end of the week - Ana gave a fantastic Dept talk - then we got to play Noah’s cells on the AFM

Finally!!!!

ÅNGSTRÖM-RESOLUTION FLUORESCENCE MICROSCOPY. Can we do structural biology with an optical microscope? Yes! Check out how we resolved *single bases of DNA* and much more using fluorescence microscopy, out on 24.05.2023 in Nature! @natureportfolio.bsky.social [re-post from Twitter]