Registration deadline 20th Dec! We have generous travel grants for early career researchers! April is a beautiful time to visit China!

The review by Banani, Lee, Hyman & Rosen (NRMCB 2017) www.nature.com/articles/nrm... on biomolecular condensates has >6000 citations. It… 1. Introduced a broad definition of “biomolecular condensates,” promoting acceptance that a unifying mechanism may underlie all membrane-less compartments.

🚨Reposts appreciated‼️If I had read this PhD offer five years ago, I wouldn’t have hesitated for a second to apply 😉 Passionate about gene regulation, chromatin, and developmental biology? Just contact @radaiglesiaslab.bsky.social at @ibbtec.bsky.social 🧬✨ #PhD #3DGenome

In this work we show that you don’t have to target the main players in disease….instead you identify and target what they depend on!

We're still accepting submissions for our 'Cell Biology of the Nucleus' special issue, which is being guest edited by @abbybuch.bsky.social and Megan King (@luskinglab.bsky.social). Submission deadline: 5 January journals.biologists.com/jcs/pages/nu... #nucleus #notforprofit #freetopublish

Myosin VI orchestrates estrogen-driven gene expression in breast cancer cells. https://www.biorxiv.org/content/10.1101/2025.11.13.688007v1

We are very happy to share our new PrePrint: Myosin VI orchestrates estrogen-driven gene expression in breast cancer cells. www.biorxiv.org/content/10.1... We characterise how Myosin VI is a key regulator of the Estrogen Receptor. Perturbation of Myosin VI impedes ER functionality.

A PhD position is available in the lab of @zech-lab.bsky.social co-supervised @christoseland.bsky.social An exciting project to understand cellular ageing in health and disease www.findaphd.com/phds/project... #CellBio #SuperResolutionMicroscopy #MolecularBio #AgeingResearch #PhDOpportunity

🔬Want to develop a blood test for dementia? A fully funded PhD position is available in our lab to probe and detect single molecules! Join our team @york.ac.uk ! Find out more & apply by 4th Dec: tinyurl.com/yt36p9tx @ybri-uoy.bsky.social @ei-science.bsky.social @timcraggs.bsky.social

Please repost - Multiple PhDs available www.findaphd.com/phds/project... www.findaphd.com/phds/project... www.findaphd.com/phds/project...

Please Repost! Tobi Zach and I have an MRC DiMeN PhD position available! Come join us! www.findaphd.com/phds/project...

It’s Halloween so time to make the cells scream!

Excited for our next special issue and looking forward to working with Abby Buchwalter (@abbybuch.bsky.social) and Megan King (@luskinglab.bsky.social)! Working on the cell biology of the nucleus? Send your papers our way! #notforprofit

Phantastic review of SPT method and analysis. Great resource for every single molecule tracking enthusiast! Congratulations, @gebhardtlab.bsky.social

Yesterday we had the School of Medicine and Population Health PGR symposium - a fantastic range of talks and posters from our students! We had excellent career sessions from Faith Nutter Howard David King and Amy Turner Thanks to our ECRs who gave a useful and honest take on finishing a PhD.

Announcing a new @embo.org Workshop on "Intracellular mechanics and organelle mechanobiology" that we are organizing with Michael Krieg and Verena Ruprecht at @icfo.eu (Barcelona) on 16-20 February, 2026. Please, repost and spread the word! 🙏 #EMBOmechanobio meetings.embo.org/event/26-org...

Doubling up on the measurements and toys today - so great and useful to have this kit next door to each other!

Postdoc positions open in my lab (Francis Crick Institute) to study 1. initiation of DNA replication. 2. chromatin replication/epigenetic inheritance. Great for biochemists, biophysicists and cryo-EM/cryo-tomography scientists. Deadline 3 August 2025. crick.wd3.myworkdayjobs.com/External/job...

This is a piece that I and @karsten-rippe.bsky.social discussing a lot, and a topic that is very close to my heart. The editors @naturerevgenet.bsky.social gave us the stage to do so, and the final version of our review is now available under this link: rdcu.be/erP1u A short thread follows 1/n

The QS World University Rankings 2026 have just been released and we’ve placed 92nd within the World Top 100! Huge congratulations and thanks to everyone in the University of Sheffield community for this achievement; from staff and students to alumni, supporters and friends around the world!

🚀 Manual mask annotation slowing you down? 💡 SAMJ is a new ImageJ/Fiji plugin using Segment Anything (SAM) for fast, interactive segmentation — no GPU needed, one-click install, real-time results. 🔬 Perfect for large biomedical images. arxiv.org/abs/2506.02783 #AI #Bioimaging #ImageJ #OpenSource

If heterochromatin is really a liquid-like condensate, why is it not spherical? We investigated whether mechanical interactions between a condensate and a fiber network can explain the variety of morphologies seen in phase-separated nuclear compartments www.biorxiv.org/content/10.1...

Back again!

Applications are now open for the 4th edition of the “Ecole de Physique des Houches” on Fluorescence Markers for Advanced Microscopies, a WE-Heraeus seminar. March 15th-20th 2026 Join us to learn everything you wanted to know about Fluorescent Markers for advanced microscopies.

Back in Harwell again for a late night reagent drop!

Quick visit back to Sheffield for more samples complete!

Back in the lab’s second home for two weeks!

Thank you for all the donations! This reel sums up the walk! www.instagram.com/reel/DJSC8HL...

Final week of fundraising- thanks for all the donations- an amazing amount has already been given! www.justgiving.com/team/thalia

Thank you for all the donations! It makes a massive difference to the charity and families! . www.justgiving.com/team/thalia

Less than two weeks to go! Thanks for all the donations! www.justgiving.com/team/thalia

Fantastic coverage from BBC Look North! . www.bbc.co.uk/programmes/b...

Early start media day! So proud to talk about Thalia…Morning radio then BBC Look North later . #cancer #braintumours #childhoodcancer

Here we share our opinions on "Practical considerations for data exploration in quantitative cell biology" journals.biologists.com/jcs/article/... Joanna, Hanna and I worked quite a bit on this piece and I hope you find it useful Many thanks to @jcellsci.bsky.social for publishing it

Day in the life of an academic - smFRET onto Lattice light sheet then delivering an afternoon workshop

Some great talks coming up this morning!

We are walking the Ullswater Way with OSCAR's Paediatric Brain Tumour Charity in May. Learn more and donate here: www.justgiving.com/team/thalia #braintumours #childhoodcancer #cancer

Like plucking a tiny guitar string!

How can we hope for things to improve when I send @braintumourrsch.bsky.social letter to our MP @JakeBenRichards then get a reply about Pancreatic cancer! Not good enough!

The Rare Cancers Bill is a major milestone! We've joined forces with rare cancer charities to push for this game-changing legislation, bringing hope for better research and treatments. bit.ly/4kHEOfD #RareCancersBill

Just out from @kazu-maeshima.bsky.social www.biorxiv.org/content/10.1...

We are so proud of how Thalia has handled the past two years and continues to approach every day! Brain tumours are devastating and we desperately need more treatments to provide options for families!

Are PhDs losing their lustre? Why fewer students are enrolling in doctoral degrees www.nature.com/articles/d41...

Fantastic few days on a grant panel in Poland - fantastic level of science and nice to explore Krakow!

🔎 Looking to start a PhD in Sept 2025? The Crick Institute spring round for PhD recruitment is open! If you are interested in actin cytoskeleton and imaging 🔬 then check out my project on role of Arp2/3 iso-complexes in regulating invadopodia👇please RT www.crick.ac.uk/careers-stud...

Currently in Krakow for a grant panel……only one news story here!

Can you explain your doctoral research through interpretive dance? The 17th annual #DanceYourPhD competition is open! Submit by 28 March for a chance to win $2000: https://scim.ag/4gKMnz9

In their #OpenAccess Review, Marta Gawor, @christoseland.bsky.social and colleagues discuss how nuclear myosins and actin regulate nuclear architecture and mechanics. journals.biologists.com/jcs/article/...

There is plenty to complain about in UK HE at the moment but a lot of the environment and atmosphere can be raised by academics supporting each other…that is within our power…it is a choice not to bother!

Excited to share the first paper from my lab 🤩 - a great collaboration with Dani Fachinetti lab - we discover a #mechanosensitive nuclear envelope #checkpoint that arrests cells directly post chromosome mis-segregation rdcu.be/d5AC9 👇🧵 #cancer #mechanics #p53 #chromatin