Something is happening at @ei-science.bsky.social HQ… Can’t wait to show you all! But I’m going to have to - won’t be long now.

Great session with the Masters students today @unisheffieldlib.bsky.social getting them all set up on @linkedin.com and more importantly here on @bsky.app Please do give them a follow when you see them posting on here - part of their ‘homework’ this week ;) Just posting on my way out…

👀 At #BPS but haven’t stopped by booth 401 yet? Meet the team to discover how you can unlock the ultimate #single-molecule resolution at your benchtop, generating high-impact insights into #biomolecular interactions and dynamics. See you there! @biophysicalsoc.bsky.social #biophysics #lifescience

🚀 Big news from @timcraggs.bsky.social x #BPS2026: meet the new EI-FLEX Pro! Automated alignment + focus, real-time analysis with publication-ready plots, modular upgrade to 96/384 wells, no darkroom or optical table, compact benchtop. Meet us at booth 401 or get in touch for a demo! #singlemolecule

I'm a bit late with this, but awesome to see it out in the wild! A real tour de force from @dozenoaks.bsky.social @timcraggs.bsky.social An amazing example of why we need to think more about flexibility in our biological questions! www.cell.com/iscience/ful...

New paper out! i-Motif, not G-quadruplex, stability regulates insulin expression - published in @narjournal.bsky.social Team effort driven by Dr Dilek Guneri supported by Dr Chris Morris, @timcraggs.bsky.social, @yiliangding.bsky.social and Prof Steve Smith academic.oup.com/nar/article/...

Congrats to Jamie et al! Our latest @york.ac.uk work dissecting the structural landscape of the Rep Helicase is now out in Nucleic Acids Research! 🧬🔬 @timcraggs.bsky.social @agnesnoy.bsky.social @bpsiyork.bsky.social @dr-mahmoud.bsky.social @single-mole.bsky.social 👇 tinyurl.com/bdznxur3

🗣️ Keynote Speaker: @sulianamanley.bsky.social 👥 Mentoring Session: Careers Across Biophysics featuring @valdavinson.bsky.social @timcraggs.bsky.social @sulianamanley.bsky.social @esisamakis.bsky.social 📈 Selected talk and poster presenters: You! ☀️ Please repost, share and we'll see you in June!

Join Kuang and @timcraggs.bsky.social on 20th November to discuss his findings in more detail as part of our next Exciting Seminar - 'Mapping the global conformation of the Rag GTPase heterodimer with single-molecule FRET' > us06web.zoom.us/meeting/regi... 🧵 4/4 #structuralbiology #biophysics

Can't decide if you like Biochemistry, Chemistry or Biophysics? Do all three! The bonus? You get to learn advanced biophysics with Prof Sarah Harris and @timcraggs.bsky.social and be exposed to the dynamic environment of @ei-science.bsky.social Application information: lnkd.in/eW9VxNBW

Opening the London Stock Exchange - that’s all…

📢 Our Exciting Seminars are back! Join @timcraggs.bsky.social & @shenk0128.bsky.social on Nov 20 for 'Mapping the global conformation of the Rag GTPase heterodimer with single-molecule FRET' > us06web.zoom.us/meeting/regi... #biophysics #lifescienceevent #molecularmedicine #biochemistry #smfret

Love the optics here - see the reflection! We are welcoming a lot of people to @ei-science.bsky.social getting great data on their own biological systems for prelim data for grants. It’s nice to have a greta space to welcome them to! Is there an #smFRET experiment you’d like to try? Ping me here!

🔬Want to develop a blood test for dementia? A fully funded PhD position is available in our lab to probe and detect single molecules! Join our team @york.ac.uk ! Find out more & apply by 4th Dec: tinyurl.com/yt36p9tx @ybri-uoy.bsky.social @ei-science.bsky.social @timcraggs.bsky.social

🚀 Since spinning out in 2021, our journey has been an Exciting one! Thrilled to see our CEO & founder @timcraggs.bsky.social named Entrepreneur of the Month by Insider Magazine. Read Tim’s comment below and the article here 👉 flickread.com/edition/html... #entrepreneur #singlemolecule #sheffield

Discover how single-molecule fluorescence reveals transient DNA–protein interactions, kinetics and conformational changes, and more. Meet @timcraggs.bsky.social & Paul Wheeler at next week’s events - email [email protected] to schedule! #biophysics #smfret #fcs

What is single-molecule FRET? Watch @timcraggs.bsky.social explain how this technique measures nanometer-scale distances and captures single-molecule conformations - youtu.be/BpCsTVJkQyE #structuralbiology #moleculardynamics #discovery #smFRET

🙌 Excited to share that our CEO @timcraggs.bsky.social has been elected to @biophysicalsoc.bsky.social alongside Robert Best, Tanja Mittag & Kandice Levental. Congrats also to Enrique M. De La Cruz, elected President-elect! #biophysics #lifescience #biophysicalsociety

Holiday time! So good to recharge with family…

🚨Job Alert: My department in UNSW Sydney is recruiting a teaching-only Lecturer in Biophysics. The lecturer will play a key role in the pedagogical development and delivery of courses and practicals in the new undergraduate (BSc) major in #Biophysics that we are launching from 2026. #AcademicBsky 🧪

🤔 What if we could detect disease from a single molecule before symptoms even appear? This isn’t just innovation. It’s a shift in how we understand, detect, and prevent illness. Molecular insights are unlocking a new era in human health. #innovation #lifescience #biophysics

Come on England! 🏴󠁧󠁢󠁥󠁮󠁧󠁿

Come on England!! Always make is wait - but what a result!

Are you a @biophysicalsoc.bsky.social member? Vote in the 2025 election by 01/08! @timcraggs.bsky.social is nominated as Industry Rep. We encourage everyone to vote for this important cause, regardless of who you're voting for 🙂 www.biophysics.org/elections/bp... #biophysics #lifescience

Voting in the KPMG Private Enterprise Tech Innovator in the UK competition is open! Show Exciting Instruments - and Yorkshire and the North East - your support by voting below 👇 app.sli.do/event/dkwYDn... #innovation #startups #deeptech #yorkshire #sheffield

Forget what you think you know about single-molecule fluorescence spectrometry instruments! Introducing the EI-FLEX... Find out more and request a tech spec > bit.ly/45AqRLv #singlemolecules #biophysics #smfret #fcs #innovation

The antihero in my story “Crisis Actors” uses cylindrical mirror anamorphism as an “encryption” technique [he’s not very bright], but I’d never seen it done with 3D objects rather than just flat images until I stumbled on this article about the sculptor Jonty Hurwitz.

🇮🇹 The countdown to #EBSA2025 is on! @timcraggs.bsky.social, Paul Wheeler and @dr-mahmoud.bsky.social will be on hand to discuss all things single molecule! Book a catch up here > meetings-eu1.hubspot.com/pwheeler/ebs... #EBSA #biophysics #singlemolecule

Swag day! Loving the new branding @ei-science.bsky.social Great work @jessicaei.bsky.social And not on here Dr Paul Wheeler!

The Wadsworth Center is expanding it's research focus on #virology /vector-borne diseases! www.asmcareerconnections.org/job/research-scientist-5-g-31/78488664/ This is a unicorn assistant prof equivalent position with 12-month hard money salary and no teaching commitments (!) Reposts appreciated 🙏

First haircut!

Applications are now open for the 4th edition of the “Ecole de Physique des Houches” on Fluorescence Markers for Advanced Microscopies, a WE-Heraeus seminar. March 15th-20th 2026 Join us to learn everything you wanted to know about Fluorescent Markers for advanced microscopies.

Half way to 90! Here’s to the next 45 years! Awesome time celebrating with my family - carting then steak.

Summer is here!

In 2016, @timcraggs.bsky.social had a problem: He needed an instrument he couldn’t afford. So, he built one! His mission: → To democratise the smFRET method and make it accessible to as many labs as possible. In 2025, Exciting Instrument is speeding up (exciting announcements coming up!) 🚀

Europe’s choice is clear. To put science at the heart of its economy. To become the home of scientific freedom and collaboration. And to welcome talent from all over the world. I’m glad to present the first elements of our Choose Europe Initiative. → europa.eu/!TTbWbJ

Ok people - I’ve not been to the cinema in a while - but was stunned at the price for this little lot… any guesses?

Well done Steve - congrats!

Are you in the mood for: - Nice single-molecule data - Technical discussions on smFRET - What’s coming next to better support the users? You can get it in a webinar replay hosted by @timcraggs.bsky.social Guests: Hermia Kung, @steve-quinn-lab.bsky.social Link: www.youtube.com/watch?v=9eq-...

When they go low, you go high, said a very wise woman Just goes to show how pathetic Europe is exactly 💪🏻🧪 (Well done European Commission and ERC)

I’m the fastest! Actually - that’s not entirely true. Mahmoud will get your smFRET experiment up and running in a matter of seconds - with data analysed in real time and streamed to your phone / laptop in minutes. Come chat at Booth 18 #POL2025 Physics of Life = Biophysics = Molecular Biology

The most exciting biophysics meetup this month is happening in the UK! Physics of Life | Harrogate | 24 -27 March Exciting Instruments will be there! If you like talking single-molecule biophysics: Don’t forget to pass by booth 18 to meet @timcraggs.bsky.social and @dr-mahmoud.bsky.social

On this day in 1879, Maud Menten was born in Port Lambton, Ontario. In her work as a medical researcher, she became a leading expert in histochemistry and enzyme kinetics while fighting against sexism in her field. Let's learn more about her life! 🧵1/10

📢 Fully-funded PhD position! 💷 🌍 Open for international applicants ⏰ Only 3 more days to apply Join me and @timcraggs.bsky.social for a fascinating biophysical exploration of proton circuits in biology. www.findaphd.com/phds/project... @sheffielduni.bsky.social

Don’t miss out! Come for @steve-quinn-lab.bsky.social Stay for awesome data from undergraduate summer student Hermia King. Leave before Tim gets too excited and you all end up buying a benchtop instrument for smFRET and FCS ;)

🔔 Happening TOMORROW: → 3 scientists → 2 case studies → 1 roundtable discussion with @timcraggs.bsky.social , Hermia Kung and @steve-quinn-lab.bsky.social Join us live When: 11th March 2025 | 5 PM GMT (12 PM ET) Why: To talk about single-molecule studies using smFRET. Where: buff.ly/J5P2J8s

We have got to do better than this…

A friend included this anti-acknowledgement section on her PhD thesis. She also added the proposition: “Systematic bullying and undermining of girls and women in STEM starts early on and is the reason why they do not stay in science and related fields.” Absurd we still need to go through this 🧪👩‍🔬

🚨 Exciting Seminar coming up! → Unravelling the FLEXibility of DNA hairpins and novel RNA systems with @timcraggs.bsky.social , Hermia Kung and @steve-quinn-lab.bsky.social ⏰ 11th March 2025 | 5 PM BST (12 PM ET) 🔥 Bonus: A roundtable discussion! Register here: buff.ly/J5P2J8s

Awesome PhD opportunity in a great collaborative team - and maybe even some single-molecule FRET!!