Supercoiling not only brings DNA to life (and makes it dance) but also changes how key proteins such as #CRISPR interact with it. Thanks @qmsmith.bsky.social for the brilliant collaboration, Sylvia for developing an amazing new #imageanalysis pipeline & @eddierollins.bsky.social for beautiful #AFM.

Two post-doctoral positions open in our lab. We're looking for people with expertise in molecular microbiology and/or genome-scale tools. Initially 3 yrs, posts could be extended for upto 8 yrs. If you'd like to know more about us take a look at www.graingerlab.com www.jobs.ac.uk/job/DQY475/r...

Registration is open for the #CCPBioSim Annual Conference, 6-8 July, Bristol, UK! See: www.ccpbiosim.ac.uk/bristol2026 Delighted to be hosting the conference @bristoluni.bsky.social, with the theme "Biomolecular simulation across scales, for understanding and design" #compchem #compbio #biodesign

Congrats to Jamie et al! Our latest @york.ac.uk work dissecting the structural landscape of the Rep Helicase is now out in Nucleic Acids Research! 🧬🔬 @timcraggs.bsky.social @agnesnoy.bsky.social @bpsiyork.bsky.social @dr-mahmoud.bsky.social @single-mole.bsky.social 👇 tinyurl.com/bdznxur3

📢 Interested in #chromosomes 🧬 & #archaea thriving at the edge of life? PhD project in York,UK on how archaea pass on their genome to daughter cells.Friendly supervisors: me, @steve-quinn-lab.bsky.social & @georgerheath.bsky.social www.findaphd.com/phds/project... 📅 January 7, 2026 Please RP🙏thx!

Would you like to fight against antimicrobial resistance (AMR) developing antibiotics? Apply to the PhD opportunity below and come to York. Collaboration with colegroupncl.bsky.social, @dghilarov.bsky.social and Inspiralis Ltd. Fully funded via DiMeN DTP 💡 www.findaphd.com/phds/project...

Check our latest publication in #JACSAu @ACSPublications with Elliot Chan and @bpsiyork.bsky.social, where we describe how the bacterial protein HU binds DNA at atomic resolution. Thanks to EPSRC for funds and @n8cir.bsky.social and hecbiosim for computational resources. pubs.acs.org/doi/10.1021/...

#BioPhyChrom25 gala dinner at the 14th century #Hospitium venue in York, and @agnesnoy.bsky.social talk. Lots of discussion and ideas for BioPhyChrom2027… Great vibes and atmosphere! @biophychrom.bsky.social @damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social 🧬

Our community letter on #FAIR principles in #moleculardynamics simulations has been published on @naturemethods.bsky.social 🎉

This is one of the conferences where I have genuinely learned more. Delighted to contribute to this vision article.

Were you interested in our last paper published in Phys. Rev. Lett. (with Matthew Burman at the University of York) but found it too hard to follow? Then, look at the piece from @sciencex.bsky.social where it is explained in more plain terms with the help of Ingrid Fadelli

Our last paper just appeared in Physical Review Letters. We studied how linear DNA is distorted by torsion and tension using all-atom simulations. Excellent work from Matthew Burman's EPSRC-funded PhD. Thanks to N8 CIR and HecBiosim for computational resources doi.org/10.1103/Phys... See thread 👇

I am very excited that I will participate in this workshop!

Registration is now open for The Biology and Physics of Prokaryotic Chromosomes meeting in York, UK. 16-19 September 2025