Congrats to Jamie et al! Our latest @york.ac.uk work dissecting the structural landscape of the Rep Helicase is now out in Nucleic Acids Research! 🧬🔬 @timcraggs.bsky.social @agnesnoy.bsky.social @bpsiyork.bsky.social @dr-mahmoud.bsky.social @single-mole.bsky.social 👇 tinyurl.com/bdznxur3

Our latest paper is in ACS Omega! We reveal how detergents remodel membranes before solubilization using a simple fluorescence dequenching assay, catching nanoscale intermediates. 👇 pubs.acs.org/doi/10.1021/... Congrats to Claudia, Katie and 3 UG students (Emily, Lauryn and Chris) from the team!

🚨Only 2 more weeks to apply for our fully-funded PhD position @york.ac.uk! Want to pioneer a blood test for dementia, detect single molecules & spend time in industry with @ei-science.bsky.social?! Apply by 4th Dec: tinyurl.com/yt36p9tx It doesn't get any more EXCITING! 🔬🩸🧪

📢 Interested in #chromosomes 🧬 & #archaea thriving at the edge of life? PhD project in York,UK on how archaea pass on their genome to daughter cells.Friendly supervisors: me, @steve-quinn-lab.bsky.social & @georgerheath.bsky.social www.findaphd.com/phds/project... 📅 January 7, 2026 Please RP🙏thx!

🔬Want to develop a blood test for dementia? A fully funded PhD position is available in our lab to probe and detect single molecules! Join our team @york.ac.uk ! Find out more & apply by 4th Dec: tinyurl.com/yt36p9tx @ybri-uoy.bsky.social @ei-science.bsky.social @timcraggs.bsky.social

We are delighted that our latest @york.ac.uk & @ybri-uoy.bsky.social work showcasing our photonic biosensor for Alzheimer's disease blood biomarkers has been published in @optica.org! 👇 opg.optica.org/optica/fullt... Thanks to @alzheimerssoc.bsky.social & @alzheimersresearchuk.org for support!

Congratulations to Dr Fran D'Rozario from our @york.ac.uk team for successfully defending her thesis! Thanks also to Prof Paula Mendes & @bpsiyork.bsky.social for examining, and to Prof Steve Johnson for supervising. Well done Fran!

New preprint! 🚨 I'm delighted to share our latest @york.ac.uk & @ybri-uoy.bsky.social pre-print: "Detergent-Triggered Membrane Remodelling Monitored via Intramembrane Fluorescence De-Quenching." Congratulations to Claudia from the team on her first manuscript! 👇👇 www.biorxiv.org/content/10.1...

We are delighted to announce that our latest work - a handheld photonic biosensor for Alzheimer's disease blood biomarkers - has been accepted for publication in Optica! Check out the pre-print... 👇👇 arxiv.org/abs/2504.08476 ...and BBC story below: www.bbc.co.uk/news/uk-engl...

🚨 New preprint!🚨We introduce a DNA-scaffold strategy for efficient dye labelling of structured RNAs, enabling #smFRET studies of freely-diffusing SARS-CoV-2 pseudoknots🧬 👉 biorxiv.org/content/10.1... #smFRET #RNA #biophysics #SARSCoV2 #singlemolecule #Covid

🧬New Pre-Print!🧬 PhD candidate Fran D'Rozario explores how pH-sensitive DNA triplexes retain reversible switching in solution, and when densely immobilized on surfaces - a step towards hybrid electronic DNA devices? 👇👇 biorxiv.org/content/10.1... #DNAnanotech #bioelectronics #smFRET #DNAmachines

New job opportunity! The Lindemann Trust is recruiting 2 freelance roles: a Trusts and Grants Fundraiser and Philanthropy Events Fundraiser. For more info, and to apply, visit: lindemanntrust.co.uk/support/ Closing date: Tuesday 19th August.

🚨New Preprint! Latest research led by @jemmabetts.bsky.social & @chillzaa.bsky.social reveals the structure of a protein-dependent riboswitch, revealing new mechanistic principles that could inspire novel antivirals! Thanks @ukri.org, @ei-science.bsky.social, @ybri-uoy.bsky.social for support! 🔬

Congratulations to Dr Sarah Graham @york.ac.uk #Physicsoflife group for successfully defending her thesis! Thanks also to Dr Tara Sabir & @agnesnoy.bsky.social for doing the honours as examiners, @bpsiyork.bsky.social for co-supervising & @chillzaa.bsky.social for all the help along the way!

The heat was brutal, and the second half was gruelling. So chuffed to have made it through the 26.2 miles! Thanks London and @alzheimersresearchuk.org that was a blast!

26.2 hours until until I take on #londonmarathon2025 , running for @AlzResearchUK ! Every step is for a future free from dementia. Let’s do this! justgiving.com/page/runlabrun

We are excited to share our latest pre-print, now available on @arxiv.bsky.social: our latest photonic biosensing platform for blood-based Alzheimer's Disease biomarker detection! Check it out! 👇👇 arxiv.org/abs/2504.08476 @ybri-uoy.bsky.social

It’s finally time for the taper! My legs are delighted to share that they have completed the final long training run! London Marathon 2025 is just 2 weeks away! #inpain 🏃 Donations to @alzheimersresearchuk.org , who fund critical research are enormously appreciated! justgiving.com/page/runlabrun

Blood biomarkers are beginning to revolutionize #Alzheimers diagnosis and have potential to offer early detection. Could emerging blood test technologies transform patiet care? Check out my editorial, out now in @jprecmed.bsky.social 👇👇 tinyurl.com/nwk34t7k #Biomarkers #Dementia #Diagnostics

Excited to be running #londonmarathon 2025 in support of @alzheimersresearchuk.org! The charity does so much to support ground-breaking dementia research! Any support for their mission, however small, would be massively appreciated and treasured so much! www.justgiving.com/page/runlabrun

🚨 Exciting Seminar coming up! → Unravelling the FLEXibility of DNA hairpins and novel RNA systems with @timcraggs.bsky.social , Hermia Kung and @steve-quinn-lab.bsky.social ⏰ 11th March 2025 | 5 PM BST (12 PM ET) 🔥 Bonus: A roundtable discussion! Register here: buff.ly/J5P2J8s

We’re on the way to #Birmingham for #ARUKConf2025! Excited to showcase our latest tech for blood based biomarker analysis and learn more about the latest developments in #dementia research! Come chat with us - we’re a friendly bunch! 🔬📈📊🥼

We're all set for @biophysicalsoc.bsky.social #bps2025! Come learn more about our team's biosensing innovations for blood-based biomarker detection! Katie will showcase a new nanopillar-based approach for multiplexed analysis of Alzheimer's biomarkers! Sunday Feb 16th @ 9.45! 📊🩸🧪

We're all set for @biophysicalsoc.bsky.social #bps2025! Come learn more about our team's biosensing innovations for blood-based biomarker detection! Katie will showcase a new nanopillar-based approach for multiplexed analysis of Alzheimer's biomarkers! Sunday Feb 16th @ 9.45! 📊🩸🧪

🚨 I'm delighted to announce a fully-funded PhD studentship (October 2025 entry) in collaboration with the Pirbright Institute. Are you interested in FMDV genome replication and packaging? Fascinated by structure and RNA-protein interactions? More info here: www.findaphd.com/phds/project...

Our latest work showcasing a resonant Young's slit interferometric biosensor for the ultrasensitive detection of Alzheimer's disease biomarkers has been accepted for publication! Congrats to Stefanus, Katie & Augusto from the team! Thanks to @alzheimerssoc.bsky.social & @york.ac.uk for support! 🔬🧪

Still time to apply for this PhD project with the awesome 🙌 @steve-quinn-lab.bsky.social, @georgerheath.bsky.social and me. By the way, York is a beautiful 🤩 historic city! Please repost, grazie 😊 🌷.

We have 4 fully funded #PhD positions available in York! Interested in single molecule biophysics, structural biology, biochemistry and/or physical chemistry? Get in touch! We have state-of-the-art labs in a fun-filled city! Come join us! DM for more or check out: sites.google.com/york.ac.uk/q...

📢 Interested in chromosomes and microbes thriving at the edge of life?PhD project in York-UK on chromosome segregation in #Archaea. Supervised by me, @Steve Quinn & @georgerheath.bsky.social www.findaphd.com/phds/project... Open to Applicants Worldwide! 📅 January 6, 2025 #microsky #archaeasky