Exciting work led by @nano-chalmers.bsky.social delivered in collaboration with @georgerheath.bsky.social introducing a rationally designed DNA origami system for the multiplexed detection of miRNA in crude RNA extracts via nanopore sensing.

Squeeze more out of your AFM images with NanoLocz v1.3 💪 Download the updated version here: github.com/George-R-Hea...

Excited to report our latest research on new “molecular glues” that specifically lock the BRCC36 isopeptidase complex (BRISC) in an autoinhibited state and reduce interferon signalling. This first-of-its-kind approach could reshape how we target large deubiquitylase (DUB) complexes. rdcu.be/edRwF

What a contribution this article is to the bioAFM community. 👍👍👍 www.nature.com/articles/s41... #AFM

The abstract submissions deadline for #mmc2025 has been extended! Submit your abstract by *Friday 28 February* and join our impressive line-up of speakers! rms.org.uk/resource/mmc... @rmsearlycareer.bsky.social @bioimaginguk.bsky.social @yorkbioimaging.bsky.social @micro-au.bsky.social

📢Abstract submissions deadline for #mmc2025 is *tomorrow* (14 February). Don't miss the chance to present your work at Europe's largest #microscopy and #imaging event taking place this year! Abstract submissions: mmc-series.org.uk/conference/a... @rmsearlycareer.bsky.social

📢 New round of PhD studentships. Open to applicants worldwide. 📅 Deadline 14th March www.findaphd.com/phds/project... #microsky #archaeasky #chromosome 🧬🧬🧬 @steve-quinn-lab.bsky.social @georgerheath.bsky.social Join us in beautiful York, UK!

Check out the latest work on RCD-1 from our lab: www.nature.com/articles/s41... Congrats to my labmates! 👏 #AFM #RCD-1

Postdoc Varun Gupta will be presenting some great AFM in the 1st session of the Linz Winter Workshop this weekend ⛷️👏

👋👋 Hi everyone! The Astbury Centre is now on Bluesky. Follow along for updates about exciting Astbury Centre science. For now, we have put together a starter pack of members of the Astbury Centre community.

15th January is the abstract deadline for the upcoming #AFMBioMed2025 in #Barcelona! New formats, events… I wouldn’t miss it—save the date #April2025!

Proud to be part of this paper published in @naturecomms.bsky.social. Using high-speed AFM, we have visualized the real-time translocation of substrate polypeptide by the single molecule of SecYEG-SecA!!! Please check this amazing video taken by high-speed AFM!!! www.nature.com/articles/s41...

Please share, we have #PhD opportunities for anyone interested in filming the #Biophysics of life at the nanoscale. Full details at: heath-afm-lab.github.io/positions/ Projects based around developing and applying High-Speed Atomic Force Microscopy methods to understand molecular dynamics.

📢 Interested in chromosomes and microbes thriving at the edge of life?PhD project in York-UK on chromosome segregation in #Archaea. Supervised by me, @Steve Quinn & @georgerheath.bsky.social www.findaphd.com/phds/project... Open to Applicants Worldwide! 📅 January 6, 2025 #microsky #archaeasky

AFM starter pack. Sorry if I missed anyone, relatively small numbers at the moment. Please share, nominate others/yourself (any career stage). I will also try to add incoming new users regularly. go.bsky.app/MSz2t33

First attempt in a (loosely defined) Single-Molecule Biophysics starter pack. Please share and (self-) nominate. go.bsky.app/CteFZM5

Now out in NSMB for those who missed our biorxiv back in 2023.. bacterial ESCRT-III-like #Vipp1 forms dynamic spiral filaments on membrane! Spirals are springs that drive 3D ring formation in the spiral centre! 😵‍💫 wonderful collaboration with Adai Colom’s lab and @rouxlab.bsky.social rdcu.be/dZSPQ

Delighted to welcome @eddierollins.bsky.social to the group as a new postdoc! Eddie brings a wealth of expertise in bioAFM and will be applying his skills to develop high-speed AFM methods to better understand protein dynamics and interactions.

Real time view of High Speed AFM data capture at 35fps. This is a 20nm x 20nm area showing an annexin V trimer rotating within a lattice. (Data from 2022) #AFM #microscopy

NanoLocz: Image analysis platform for AFM, high-speed AFM and localization AFM https://www.biorxiv.org/content/10.1101/2023.11.23.568405v1