🚀 Here comes the next big step in our Exciting journey! Thrilled to announce the appointment of Jonathan Rigby as the Chairman of our Board. Find out more about what it means for Exciting Instruments in the press release below. #innovation #startups #biophysics #Sheffield #pressrelease

🤔 How did Groves et al. use the FLEX to reveal insights about SARS-CoV-2’s RNA polymerase? Find out here > doi.org/10.1093/nar/... Want to know more about the FLEX? Learn more, request a tech spec or book a demo on our website: excitinginstruments.com/ei-flex/?utm... #smfret #RNA #nucleicacids

👋 At the Midlands Biophysics Network meeting today? So are we! Visit our stand to chat about how we're bringing solution-based single-molecule techniques right to your benchtop - no extensive training required. #midlandsbiophysicsnetworkmeeting #biophysics #singlemolecule #smfret #fcs

Thrilled to see long-time #FRET experts moving into single-molecule work with our technology at McMaster University! Plus, our instrument now also supports University at Albany's core facility with #smFRET & #FCS! A very Exciting week! 🙌 #biophysics #singlemolecule #structuralbiology

Tim and Paul are ready and waiting at the Biology and Physics of Prokaryotic Chromosomes conference to show you how in-solution, single-molecule fluorescence spectroscopy can help visualise structural dynamics of prokaryotic protein/DNA interactions. Visit our stand for a chat! #prokaryoticproteins

Missing biomolecular dynamics at picomolar levels? The EI-FLEX makes single-molecule research quick and easy with precision and stability. Watch Dr. Quinn below and book a demo: excitinginstruments.com/contact-us/?... #singlemolecule #structuralbiology #moleculardynamics #smFRET #FCS

Heading to the Austrian Cryo-EM Symposium in November? Let's catch up! We'll be on hand to share how freely diffusing smFRET can complement this already exquisitely detailed technique #cryoEM #smfret #singlemolecule

Discover how single-molecule fluorescence reveals transient DNA–protein interactions, kinetics and conformational changes, and more. Meet @timcraggs.bsky.social & Paul Wheeler at next week’s events - email [email protected] to schedule! #biophysics #smfret #fcs

What is single-molecule FRET? Watch @timcraggs.bsky.social explain how this technique measures nanometer-scale distances and captures single-molecule conformations - youtu.be/BpCsTVJkQyE #structuralbiology #moleculardynamics #discovery #smFRET

X-ray crystallography gives static molecular snapshots with atomic precision. Freely diffusing smFRET adds dynamics, revealing alternative states, transition rates, and validating models. See how Craggs et al. (2019) used it to reveal hidden structures: bit.ly/45Vznoh #smfret #structuralbiology

💡 Measure fleeting protein encounters with ease - no dark rooms, bulky equipment, or extensive training. Our compact instrument delivers fast, publication-ready results from the bench in ambient light. 👉 bit.ly/4683zLQ #smFRET #FCS #biophysics #science

🚀 Hear ALEX and smFRET pioneer Shimon Weiss talk on origins, breakthroughs, and the future 👀 Watch the Exciting Seminar in full > youtu.be/MBI82_QKAnk #smFRET #ALEX #biophysics #structuralbiology #moleculardynamics

⚡Discovery moves faster when your software keeps up. The EI-FLEX lets you visualise data in real time, validate assays with ease & share results. Publication-ready plots + full metadata for confidence in every experiment. Book a demo 👉 bit.ly/3JzwYXE #smFRET #FCS #structuralbiology #singlemolecule

Want the latest single-molecule spectroscopy news and research, groundbreaking smFRET and FCS applications, exciting updates about our products and team, and more straight into your inbox?🚀 Subscribe > fwfh6.share-eu1.hsforms.com/2tB-S9AikSdG... #singlemolecule #smfret #fcs #biophysics

Single-molecule measurements in solution expose heterogeneity, rare events, and real-time dynamics without immobilisation, yielding precise kinetic and mechanistic insights. Learn more: excitinginstruments.com?utm_source=b... #proteindynamics #DNAproteininteractions #structuralbiology #biophysics

Curious how FCS applies to stem cells, CRISPR/Cas9 models & isolated receptors at physiologically relevant protein levels? Watch Joelle Goulding’s Exciting Seminar on FCS in biological systems 👀 youtu.be/YzFw-TLG1Bk?... #fcs #biophysics

💡Heading to #MAF2025? Check out @dr-mahmoud.bsky.social presenting at the FRET Satellite workshop, or visit him and @robertbell.bsky.social at stand 14 to see EI-FLEX single-molecule and FCS data in action! Not in Montréal? Book a demo anytime 👉 excitinginstruments.com #singlemolecule #fluorescence

🔬 Running smFRET with TIRF or just getting started? Traditional barriers holding you back? 👉 See how EI-FLEX is redefining smFRET. Watch the video + book a demo: bit.ly/474aeZA #smFRET #TIRF #singlemolecule #biophysics #molecularbiology

🙌 Excited to share that our CEO @timcraggs.bsky.social has been elected to @biophysicalsoc.bsky.social alongside Robert Best, Tanja Mittag & Kandice Levental. Congrats also to Enrique M. De La Cruz, elected President-elect! #biophysics #lifescience #biophysicalsociety

See biomolecules in action at the single-molecule level without the complexity. Meet us at #MAF2025 in Montréal (23–27 Aug) for demos of our compact, powerful smFRET instrument. Book a chat: meetings-eu1.hubspot.com/robert-bell1

💡 Find out how Professor Rhoades used FCS to investigate the cellular internalisation of disordered proteins linked to neurodegeneration in this episode of our Exciting Seminars! #fcs #biophysics #neurodegeneration #fluorescencecorrelationspectroscopy #singlemolecules youtu.be/Z7nbpW1xBpg?...

Single-molecule data reveals tiny fluctuations, rare events, and fleeting states that ensemble averages often overlook. Bring this precision to your lab. Learn more: bit.ly/4makHar #molecularbiology #structuralbiology

🚀 We're on a mission to make single-molecule fluorescence spectroscopy simple and accessible - no specialist facilities, darkrooms, or complex training needed👇 Subscribe to our newsletter for updates: www.linkedin.com/build-relati... #biophysics #singlemolecules #moleculardynamics #structuralbiology

Move beyond averages. smFRET and FCS reveal real-time, single-molecule dynamics - conformational changes, binding, diffusion - missed by bulk methods. Discover more in the 2024 NAR paper on RPA-DNA interactions: academic.oup.com/nar/article/...? #biophysics #moleculardynamics #singlemolecules

🤔 What if we could detect disease from a single molecule before symptoms even appear? This isn’t just innovation. It’s a shift in how we understand, detect, and prevent illness. Molecular insights are unlocking a new era in human health. #innovation #lifescience #biophysics

🙌 We're still on a high from opening our new office & lab at Pennine Five, alongside FourJaw & Phlux Technology, right on Sheffield’s innovation spine. Huge thanks to COGO Interiors and RBH Properties! Here’s to advancing smFRET & FCS from our new home! #deeptech #sheffield #startups

Frustrated by static structures? Single-molecule fluorescence reveals real-time dynamics, binding kinetics and molecular heterogeneity, offering true mechanistic insight. See how biology truly works. Learn more: bit.ly/3H1H1nf #singlemolecule #biophysics #moleculardynamics #smFRET #structuralbiology

Are you a @biophysicalsoc.bsky.social member? Vote in the 2025 election by 01/08! @timcraggs.bsky.social is nominated as Industry Rep. We encourage everyone to vote for this important cause, regardless of who you're voting for 🙂 www.biophysics.org/elections/bp... #biophysics #lifescience

New preprint alert! 🚨👇 I'm delighted to share the latest research from @jemmabetts.bsky.social in our group: ‘A new protein-dependent riboswitch activates ribosomal frameshifting’. Huge congratulations to Jemma for the first manuscript of her PhD! ✨ www.biorxiv.org/content/10.1...

🙌 Check out this brilliant example of our benchtop single-molecule fluorescence spectrometer in action! www.linkedin.com/posts/chris-... Great work from Chris Hill and his team in York 👏 #smfret #biophysics #singlemolecules #innovation #lifescience

Is picomolar sensitivity critical to your work? Hear Dr. Steve Quinn (Univ. of York) on how EI-FLEX revolutionised his smFRET, FCS & FCCS experiments. Learn more & get the tech spec: excitinginstruments.com/ei-flex/ Watch the seminar: youtu.be/9eq-EE70PgQ #biophysics #smFRET #FCS #FCCS

We're thrilled to be a finalist in this year's KPMG UK Tech Innovator competition! 🚀 Support UK innovation - cast your vote and help us shine! app.sli.do/event/dkwYDn... #techinnovatoruk #innovation #startup #biophysics

🇩🇪 Heading to EMBL’s Gene Regulation: One Molecule at a Time? Come chat with us about how smFRET, FCS & FCCS are transforming molecular research—and see our accessible benchtop system in action. #EMBL #EMBLSingleMolecule #singlemolecules #biophysics

Curious how the EI-FLEX brings single-molecule spectroscopy to your benchtop with minimal training? We're at the RSC Nucleic Acids Forum today - come see our intuitive smFRET, FCS, and FCCS instrument and software in action! #NAF #singlemolecules #smFRET #FCS #moleculardynamics

🔬 Check out Professor Edwin Antony below, explaining why the EI-FLEX has replaced most of the single-molecule confocal microscope instruments in his lab! Learn more about the EI-FLEX > bit.ly/3HTGiVh #singlemolecules #biophysics #moleculardynamics #smfret #fcs

Voting in the KPMG Private Enterprise Tech Innovator in the UK competition is open! Show Exciting Instruments - and Yorkshire and the North East - your support by voting below 👇 app.sli.do/event/dkwYDn... #innovation #startups #deeptech #yorkshire #sheffield

Thank you again to South Yorkshire's Mayor Oliver Coppard for officially cutting the ribbon at our grand opening event last week, and to SYMCA for part-funding our new home. Watch the video below to learn more. Credit to SYMCA for the video! #innovation #sheffield #startups #deeptech #biophysics

🇮🇹 Ciao - we're at #EBSA ready to demo our benchtop single-molecule fluorescence spectrometer and accompanying acquisition and analysis software. Visit us at stand 19 to talk all things single molecule and fluorescence spectroscopy. #EBSA25 #EBSA2025 #rome

🚀 We’ve launched our new HQ & lab at Pennine Five in Sheffield! Backed by £4M seed funding & SYMCA support, this milestone brings our UK teams together to accelerate innovation. Thanks to all who joined – a proud moment for Exciting Instruments! #startup #biophysics #Sheffield

Forget what you think you know about single-molecule fluorescence spectrometry instruments! Introducing the EI-FLEX... Find out more and request a tech spec > bit.ly/45AqRLv #singlemolecules #biophysics #smfret #fcs #innovation

🇮🇹 The countdown to #EBSA2025 is on! @timcraggs.bsky.social, Paul Wheeler and @dr-mahmoud.bsky.social will be on hand to discuss all things single molecule! Book a catch up here > meetings-eu1.hubspot.com/pwheeler/ebs... #EBSA #biophysics #singlemolecule

Great first day at #MOSBRI! Mahmoud is ready and waiting to discuss your research challenges and how single-molecule fluorescence techniques like smFRET and FCS can take your work to the next level. We’re here until Friday > lnkd.in/e3839gv7 #MOSBRI2025 #paris #biophsyics #moleculardynamics

Join our new single-molecule spectroscopy community! Ask questions, share knowledge, connect with fellow researchers and spark great conversations. Don’t research in isolation - join today! 👉 www.linkedin.com/groups/13198... #singlemolecules #biophysics #lifescience #sciencec

Our Senior Application Scientist Mahmoud is ready to discuss your research challenges at #MOSBRI and how single-molecule fluorescence techniques like smFRET and FCS can advance your work. Book a meeting here > bit.ly/4mYjN1E 🇫🇷 À bientôt! #molecularscience #MOSBRI2025 #biophysics #singlemolecule

Curious how leading academics are using single-molecule methods in their research? 👉 Download our ebook to explore applications from academic labs pushing the boundaries of what's possible. bit.ly/4myei9L #biophysics #singlemolecule #smfret #spectroscopy #lifescience #innovation

Will we see you at the Institut Pasteur for #MOSBRI2025? @dr-mahmoud.bsky.social will be there and wants to connect to discuss single molecules, spectroscopy and more! You can book a meeting with him here > meetings-eu1.hubspot.com/mabdelhamid/... #singlemolecules #MOSBRI #biophysics

Tune in to Traction: The Tech Show to hear our CEO and founder Tim talk about our origin story, our exciting fundraising success, and where we’re headed next. #sheffield #biotech #startups #innovqtion #foundersstory www.linkedin.com/posts/tracti...

Change is in the air at Exciting Instruments! Our new look reflects our bold ambition and passion for discovery. Huge thanks to everyone who’s been part of our journey - stay tuned, the next chapter is going to be even more exciting! #sheffield #startup #innovation #biophysics #foundersjourney

Everyone said it wasn’t possible, but we did it ANYWAY. With a team of 4 we built: → The company → The instrument → Demand in the life science market Now we’re speeding up on our mission of making smFRET accessible to ANY life science lab. 🚀 Want to join us? (New roles opening soon)

The Exciting Instruments evolution: 2016: Tim has a problem - he can’t afford the solution 2017: First smFRET instrument built in Tim’s lab 2021: The company was founded 2022: The first EI-FLEX instrument installed 2024: EI raises funding to speed up growth 2025: Today, we are a team of 10!