Amy Strom
@dnamystrom.bsky.social
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Chromatin and cancer and condensates. Lab Head in Discovery Oncology at Genentech. AmyStrom.com
pinned post!
If heterochromatin is really a liquid-like condensate, why is it not spherical? We investigated whether mechanical interactions between a condensate and a fiber network can explain the variety of morphologies seen in phase-separated nuclear compartments
www.biorxiv.org/content/10.1...
3 months ago
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Chuffed to be recognized with an Early Career Award for work on the chromatin-nucleated phase separation of BRD4. ✨ Give it a read!
www.molbiolcell.org/doi/full/10....
Shout-out
@drjorine.bsky.social
@brangwynnelab.bsky.social
And huge thank you
@ascbiology.bsky.social
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Interplay of condensation and chromatin binding underlies BRD4 targeting | Molecular Biology of the Cell
Nuclear compartments form via biomolecular phase separation, mediated through multivalent properties of biomolecules concentrated within condensates. Certain compartments are associated with specific ...
https://www.molbiolcell.org/doi/full/10.1091/mbc.E24-01-0046?af=R
11 days ago
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Getting Strom Lab set up!
13 days ago
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First day at my new job! I'm a Lab Head, Principal Scientist in Discovery Oncology at Genentech. I'll be searching for new targets to develop cancer treatments. 2nd photo is my newest friend on campus, decoy-ote.
@genentech.bsky.social
about 2 months ago
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The latest in my favorite love triangle: Chromatin <-(💜)-> Condensates <-(💚)-> Mechanics
add a skeleton here at some point
2 months ago
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Cancelling grants that were already competitively won and awarded is the waste and abuse.
www.nytimes.com/2025/07/10/u...
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The Surprising Scientists Hit by Trump’s D.E.I. Cuts
https://www.nytimes.com/2025/07/10/us/trump-science-nih-grants-dei-cuts.html
3 months ago
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I'm thrilled to announce my next career step-- I’m joining Genentech as a Principal Scientist & Lab Head in Discovery Oncology! I’ll be hunting new ways to target cancers using my background in disordered nuclear proteins.
3 months ago
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If heterochromatin is really a liquid-like condensate, why is it not spherical? We investigated whether mechanical interactions between a condensate and a fiber network can explain the variety of morphologies seen in phase-separated nuclear compartments
www.biorxiv.org/content/10.1...
3 months ago
5
87
28
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