There are many ways to make your voice heard and participate in all that #ISSCR2026 has to offer! Discover how to get involved, including submitting an abstract, proposing a science spotlight, hosting a meet-up hub, and more! invt.io/1bxbhh15upf @ISSCR.org

How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇

Thrilled to be selected as an #ISSCR2026 Ambassador! The @isscr.org 2026 Annual Meeting will take place in Montréal, Canada on 8-11 July 2026 & features 4 days of scientific sessions with talks from global researchers! Explore the scientific program and the ways to participate. invt.io/1bxb53avp9c

Catch up on Development presents… webinar on gut development Check out the talks of Surojit Sural @surojitsural.bsky.social & Swarnabh Bhattacharya @iamzico.bsky.social Also, register for our upcoming #DevPres on 15 October: us02web.zoom.us/webinar/regi... thenode.biologists.com/catch-up-on-...

Our next #DevPres webinar focusses on gut development with talks from Surojit Sural @surojitsural.bsky.social, Swarnabh Bhattacharya @iamzico.bsky.social and Brittany Edens, chaired by Alex Eve @amjeve.bsky.social. 📆 17 September, 15:00 BST (UTC+1) Register here: us02web.zoom.us/webinar/regi...

Thanks to @rkzwick.bsky.social for writing this excellent preview and thoughtful discussion on our recent article @cp-cellstemcell.bsky.social (t.co/TkDxt1b3DH)

Honored to receive a Pilot & Feasibility grant (P30 DK034854) from the Harvard Digestive Disease Center to explore cellular plasticity and the epigenetic drivers of inflammatory bowel disease. Excited to uncover new insights into IBD pathogenesis!

I’m thrilled to have our work—“Intestinal secretory differentiation reflects niche-driven phenotypic plasticity of a common signal-responsive terminal cell” (dlvr.it/TK2Fzl) featured in the Preview of this issue of @cp-cellstemcell.bsky.social!

Happy to present Hien’s paper on age-selective apportioning of peroxisomes as a fate determinant in adult stem cells www.nature.com/articles/s41... @metastem.bsky.social @helsinki.fi @ki.se @helsinki-biotech.bsky.social out now in @natcomms.nature.com A thread 🧵 1/9

Check out this exciting preprint from @aznarbenitahlab.bsky.social discovering a new mode of crosstalk between YAP and the circadian regulator BMAL1. Congrats @juliabonjoch.bsky.social and @guiomarsolanas.bsky.social for fantastic work and thank you for the fun collaboration!

Online Now! Intestinal secretory differentiation reflects niche-driven phenotypic and epigenetic plasticity of a common signal-responsive terminal cell #stemcells

I am excited to share my latest Postdoctoral work @cp-cellstemcell.bsky.social @cellpress.bsky.social (dlvr.it/TK2Fzl), in which we reveal that goblet and Paneth cells aren’t fixed lineages but represent dynamic states influenced by local cues. Here's a walkthrough of what we found (🧵)....

Different fibroblast subtypes propel spatially defined ileal inflammation through TNFR1 signaling in murine ileitis @naturecomms.bsky.social www.nature.com/articles/s41...

Multiple layers of γδ IEL dysregulation and loss of their immunosuppressive capacity occur before the onset of chronic ileitis www.science.org/doi/10.1126/... @nbgolovchenko.bsky.social @sciimmunology.bsky.social @edelblumlab.bsky.social

Vagal pathway activation links chronic stress to decline in intestinal stem cell function @cp-cellstemcell.bsky.social www.cell.com/cell-stem-ce...

🔦Spotlight of Peter Dempsey, @brumbaugh-lab.bsky.social et al paper: Epigenetic fluidity meets phenotypic malleability in intestinal epithelial cells by @iamzico.bsky.social and Ramesh Shivdasani at @danafarber.bsky.social http://dlvr.it/TJfVRZ

It was fun to write this Spotlight article @cp-cellchembiol.bsky.social on the recent NCB paper (rdcu.be/eayN3) by @brumbaugh-lab.bsky.social & Dempsey labs, revealing how epigenetic fluidity drives phenotypic malleability in the intestinal epithelium. www.sciencedirect.com/science/arti...

Happy to share our review on methodology for measuring and manipulating mechanical forces with specific focus on developmental biology! Congrats to authors @clemvilleneuve.bsky.social @mccreery.bsky.social and hats off to the community for developing awesome tools www.nature.com/articles/s41...

📣Funded #PhDposition! – Pls RT! Looking for a passionate PhD student to explore cellular crosstalk in #TumorMicroenvironment combining #organoids #scRNAseq &high-res imaging. Join us @VetmeduniVienna in a vibrant research environment! #CancerResearch #PhD 👉 euraxess.ec.europa.eu/jobs/302158

A perfect start in the new year! 🌱 Regenerating tissues are just an amazing spatio temporal controlled process! Our new manuscript explores how cell heterogeneity and bistability orchestrate intestinal regeneration. 🧵 biorxiv.org/cgi/content/...

Our new paper defining the role of H3K36 methylation in regulating cell fate and plasticity is available online: rdcu.be/d5AEc Thanks to our entire team for their tireless work and to the editors at @naturecellbiology.bsky.social for the opportunity!

New research in @nature.com led by Ramesh A. Shivdasani, MD, PhD, of @danafarber.bsky.social gives insight into how intestinal tumors develop. https://go.nature.com/42cMksp

Crypt density and recruited enhancers underlie intestinal tumor initiation @Nature www.nature.com/articles/s41...

New Publication Alert from Shivdasani Lab!! 🚨🚨 Adenomas don’t form just because of Apc mutations—they require cooperation between mutant intestinal crypts. Congratulations to Liam and all the authors! Thrilled to be part of this fantastic study! @nature.com rdcu.be/d5DQh

Cool study from @katemiro.bsky.social and @dfachinetti.bsky.social labs showing how chromosome abnormalities activate p53 through nuclear envelope stress 🤩 Congrats to all!

Do you want to study #cancer #microbe interactions using #organoids and #organ #chips? Have a look at our guide to co-culture platforms, just out in Int J Cancer with Jens Puschhof, Hans Clevers, Eran Elinav and fellow @emil-dkfz.bsky.social colleagues: onlinelibrary.wiley.com/doi/10.1002/...

Excited to share my new @cellcellpress.bsky.social paper from @thecleverslab.bsky.social was published today! Thanks to @hansclevers.bsky.social and all our collaborators. #organoids #stemcells #pancreas