Dana-Farber News
@danafarbernews.bsky.social
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New research in @natcomms.nature.com by @danafarber.bsky.social’s @mishabeltran.bsky.social and Varadha Balaji Venkadakrishnan, PhD, reveals how prostate cancer becomes resistant to treatment and DNA methylation and EZH2 activity drive neuroendocrine prostate cancer. ➡️
bit.ly/4sk61bg
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Crosstalk between EZH2 and DNA methylation mediates neuroendocrine prostate cancer lineage plasticity - Nature Communications
In this study, the authors identify a collaboration between the epigenetic regulators, EZH2 and DNA methyltransferase that contributes to prostate cancer lineage reprogramming.
https://bit.ly/4sk61bg
about 12 hours ago
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New research published by @danafarber.bsky.social’s Judith Agudo, PhD, and colleagues in @nature.com today reveals a new strategy to prevent the metastasis of triple-negative breast cancer. ➡️
bit.ly/4rLuOFj
1 day ago
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Cancer Grand Challenges has awarded $25 million to team ILLUMINE, a group of leading scientists around the world including @danafarber.bsky.social’s Dr. Cathy Wu, who will work to unlock the potential of the cancer dark proteome.
bit.ly/4d1AxSV
1 day ago
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"LITESPARK-022 is the first adjuvant trial in kidney cancer to show a benefit for a combination versus a PD-1 agent alone." @danafarber.bsky.social’s Toni Choueiri, MD, featured in Fierce Pharma discussing kidney cancer research he presented at #ASCOGU. ➡️
bit.ly/3MTz0nq
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A new standard? Merck's Welireg combos deliver 1-2 punch to kidney cancer
The treatment landscape for clear cell renal cell carcinoma (ccRCC) could be due for a shake-up following dual breakthroughs from Merck’s Litespark clinical trial program for Welireg. | The treatment landscape for clear cell renal cell carcinoma could be due for a shake-up following dual breakthroughs from Merck’s Litespark clinical trial program for Welireg. But one critical factor could hinder these Welireg regimens from shifting from potential treatment options to the universal standard of care.
https://bit.ly/3MTz0nq
3 days ago
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"The Cancer No One Can Explain" - Kicking off #ColorectalCancerAwareness month with this great piece in @nautil.us magazine featuring a Q&A about young-onset colorectal cancer with @danafarber.bsky.social’s Dr. Leah Biller. Read more here:
bit.ly/4b4lRju
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The Cancer No One Can Explain
The Cancer No One Can Explain: Colorectal cancer in young people has been rising for 30 years. We still don't know why—and that's killing people.
https://bit.ly/4b4lRju
3 days ago
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At
#ASCOGU26
:
@danafarber.bsky.social
’s Dr. Brad McGregor provides an update on the STRIKE! clinical trial which looks at short term intensified pembrolizumab and tivozanib for high-risk renal cell carcinoma.
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6 days ago
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Research at
#ASCOGU
:
@danafarber.bsky.social
’s Dr. Alicia Morgans provides insights from the ARANOTE trial during a poster session. The poster looks at the impact of hospitalizations on health-related quality of life and overall survival in metastatic castration-sensitive prostate cancer.
6 days ago
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"The most frightening thing is, we don’t completely understand why these rates are rising in young people without risk factors” - @danafarber.bsky.social’s Dr. Kimmie Ng speaks with 7News Boston about the rising rate of young-onset colorectal cancer. ➡️
bit.ly/4sf4bZk
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7 Investigates: Colorectal cancer cases surge among young adults - Boston News, Weather, Sports | WHDH 7News
BOSTON (WHDH) - The news hit John Veale hard.“It almost feels like a bullet through your heart,” said Veale, a Boston resident. “I remember just<a class="excerpt-read-more" href="https://whdh.com/7-investigates/7-investigates-colorectal-cancer-cases-surge-among-young-adults/">Read More</a>
https://bit.ly/4sf4bZk
6 days ago
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Congratulations to Keene Abbott, PhD, of
@danafarbernews.bsky.social
and
@bostonchildrens.bsky.social
who received the 2026 Harold M. Weintraub Graduate Student Award for his outstanding achievement during graduate studies in the biological sciences.
7 days ago
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Reimagining Cancer Research and Care in the Age of Artificial Intelligence: @danafarbernews.bsky.social’s Eli Van Allen, MD, delivers this keynote presentation at
#ASCOGU26
today at 2:15pm PT/11:15am ET.
7 days ago
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At today's
#ASCOGU
poster session:
@danafarbernews.bsky.social
’s Xiao Wei, MD, presents on the effectiveness of systemic therapies after Lu-PSMA-617 treatment in patients with metastatic castration-resistant prostate cancer.
8 days ago
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Congrats to @danafarbernews.bsky.social’s Xin Zhou, PhD, recipient of a 2026 Damon Runyon-Rachleff Innovation Award for "Extracellular reprogramming of kinase signaling pathways.” The award supports ideas with potential to impact the prevention, diagnosis, or treatment of cancer. ➡️
bit.ly/4rA75Il
8 days ago
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Expert analysis: Dr. Michael Serzan and Dr. Emre YekedĂĽz, both of @danafarbernews.bsky.social, preview the practice-changing data they expect this week at #ASCOGU. Read more in @curetoday.bsky.social:
bit.ly/46thzk5
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Experts Preview Practice-Changing Data Ahead of 2026 ASCO GU | CURE
Oncologists highlight key 2026 ASCO GU studies in bladder, prostate, kidney and testicular cancers that could reshape treatment and personalize care.
https://bit.ly/46thzk5
9 days ago
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Research in Science Advances by @danafarbernews.bsky.social’s Sabrina Camp, Kevin Bi and Eli Van Allen, MD, revealed loss of the gene BAP1 activates a tumor-intrinsic interferon signaling program, highlighting immune evasion pathways as potential treatment targets. @broadinstitute.org
bit.ly/4cEOFBl
11 days ago
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New research by @danafarbernews.bsky.social’s Amy Lee, PhD, and @mfels.bsky.social in @cp-cell.bsky.social reveals that giant DNA viruses encode a distinct & functional IF4F translation-initiation complex to drive protein synthesis, blurring the line between living cells and viruses.
bit.ly/4rS3Uew
13 days ago
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New research featured in @nature.com from Sonomi Yamaguchi of @danafarbernews.bsky.social’s @kranzuschlab.bsky.social discovers “p3diT” as a nucleotide immune signal in bacteria and suggests similar signals may function as negative regulators in human immunity. Read more:
bit.ly/3MTjLL6
14 days ago
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Targeting the RAS Oncogene in Cancer – a keynote address presented by @danafarbernews.bsky.social’s Alice Shaw, MD, PhD, at this year’s Transatlantic Exchange hosted by Dana-Farber with @gustaveroussy.fr, sponsored by Servier and presented by Medscape Medical Affairs. Register today:
bit.ly/461YzZS
17 days ago
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Cancer care and AI: Dr. Eli Van Allen will deliver the
#ASCOGU26
keynote address on “Reimagining Cancer Research and Care in the AI Age.” Read more in The
@ascopost.bsky.social
➡️
bit.ly/4rQChTp
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Dr. Eliezer M. Van Allen to Deliver ASCO GU26 Keynote on Reimagining Cancer Research and Care in the AI Age
Clinical computational oncologist Dr. Eliezer M. Van Allen will deliver the keynote address at the 2026 ASCO Genitourinary Cancers Symposium, where he will discuss the latest research on and developme...
https://bit.ly/4rQChTp
21 days ago
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Featured on @boston25news.com, Dr. Kimmie Ng of @danafarbernews.bsky.social discusses colorectal cancer risks in younger adults following the sad news of the death of “Dawson's Creek” actor James Van Der Beek. ➡️
bit.ly/4qBnIlE
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Dr. Kimmie Ng of Dana-Farber discusses colorectal cancer risks in younger people
“Dawson’s Creek” actor James Van Der Beek died after a battle with the disease.
https://bit.ly/4qBnIlE
21 days ago
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Agenda for the 5th annual Transatlantic Exchange: epigenetic therapies; microbiome-driven immunity; and cellular pathway reprogramming. Join experts from @danafarbernews.bsky.social and @gustaveroussy.fr at the 1-day event in Boston dedicated to frontiers in cancer drug research. ➡️
bit.ly/4qruni1
22 days ago
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A new study led by @danafarbernews.bsky.social’s Dr. Kai Wucherpfennig and colleagues shows that an injection of a genetically modified virus that selectively infects and destroys cancer cells can recruit immune cells to penetrate and persist deep within brain tumors. ➡️
bit.ly/4atTuee
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Virus-Based Therapy Boosts Anti-Cancer Immune Responses to Brain Cancer | Dana-Farber Cancer Institute
A team led by investigators at Dana-Farber Cancer Institute and Mass General Brigham has shown that a single injection of an oncolytic virus—a genetically modified virus that selectively infects and destroys cancer cells—can recruit immune cells to penetrate and persist deep within brain tumors.
https://bit.ly/4atTuee
22 days ago
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Donations of whole blood and platelets are urgently needed by Kraft Family Blood Donor Center due to the national shortage caused by winter storm and flight disruptions. Make an appt to support @danafarbernews.bsky.social and Brigham & Women’s Hospital patients at 617-632-3206. ➡️
bit.ly/4a3ssu2
23 days ago
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The Center for Global Health at @danafarbernews.bsky.social is excited to launch the first colorectal cancer screening program in Central Asia, partnering with Uzbekistan's Ministry of Health and National Cancer Center. Read more here:
bit.ly/4bzLivg
24 days ago
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Congratulations to
@danafarber.bsky.social
's Corey Culter, MD, MPH, who has been named to the 2026 Class of the American Society of Transplantation and Cellular Therapy (ASTCT) Fellows Program for his impact on hematopoietic stem cell transplantation and cellular therapy.
24 days ago
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The @washingtonpost.com recognized @danafarber.bsky.social's Dr. Kimmie Ng for her work in young-onset colorectal cancer. Dr. Ng is part of the 'Post Next 50,' the newspaper's annual look at 50 people shaping society in 2026. Read more here:
bit.ly/4kqFWob
25 days ago
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ICYMI: Research by @danafarber.bsky.social's Vinayak Venkataraman, MD, in the Journal of Adolescent and Young Adult Oncology confirmed that #sarcoma and its treatment greatly disrupted the lives of #AYA patients – yet earlier introduction of support services may ease some challenges.
bit.ly/3ZRpROT
28 days ago
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New research in @natneuro.nature.com by @danafarber.bsky.social's Benjamin Kann, MD, presents BrainIAC, a novel AI model designed to learn representations from unlabeled brain MRI data with potential to improve disease diagnosis and management in a variety of clinical scenarios. ➡️
bit.ly/4qk9Snp
28 days ago
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Congrats to @danafarbernews.bsky.social’s Drs. Brian Wolpin and Andrew Aguirre, recipients of a 2026 Mark Foundation-AACR-Lustgarten Foundation Early Detection Award for pancreatic cancer research. @themarkfdn.bsky.social @theaacr.bsky.social @lustgarten.org @tinaswish.bsky.social ➡️
bit.ly/4acXj7w
29 days ago
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reposted by
Dana-Farber News
Dana-Farber Cancer Institute
29 days ago
We are profoundly grateful to announce the largest single gift in our 78-year history through a new joint commitment from Josh and Anita Bekenstein and the Jonathan Lavine and Jeannie Lavine family.
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This week, @danafarbernews.bsky.social researchers will present key studies in transplant and cellular therapy at #Tandem26. Follow our coverage for updates and meeting highlights. Read more:
bit.ly/4qdQ1pW
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Dana-Farber Researchers to Present Key Transplant and Cellular Therapy Studies at 2026 Tandem Meetings | Dana-Farber Cancer Institute
Dana-Farber Cancer Institute will present new research and clinical program findings at the 2026 Tandem Meetings; the leading conference focused on hematopoietic cell transplantation (HCT) and cellular therapy. Organized by the American Society for Transplantation and Cellular Therapy (ASTCT) and the Center for International Blood and Marrow Transplant Research (CIBMTR), the meeting will be held February 4–7, 2026, at the Salt Palace Convention Center in Salt Lake City, Utah.
https://bit.ly/4qdQ1pW
about 1 month ago
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Donations of whole blood and platelets are urgently needed at the Kraft Family Blood Donor Center b/c of the national shortage due to storms and flight disruptions. Make an appointment today to support patients from @danafarbernews.bsky.social and Brigham & Women’s Hospital:
bit.ly/4a3ssu2
about 1 month ago
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Patient education & navigation significantly improve genomic testing uptake & clinical trial participation, addressing disparities in trial enrollment among underrepresented groups. @danafarbernews.bsky.social’s Dr. Nadine Jackson discusses the SURGE Trial with @curetoday.bsky.social.
bit.ly/3YU7UPq
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The Importance of Patient Education and Individualized GI Cancer Care | CURE
Patient education and individualized navigation can improve genomic testing uptake and downstream participation in genomics-based clinical trials.
https://bit.ly/3YU7UPq
about 1 month ago
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Congratulations to
@danafarbernews.bsky.social
’s Anne Gross, PhD, RN, for being named to Becker’s Hospital Review 2025 Hospital and Health System CNOs to Know list. These nursing leaders are at the forefront of the profession, creating pathways for the growth and development of emerging nurses.
about 1 month ago
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In @nejm.org @danafarbernews.bsky.social’s Otto Metzger, MD, publishes results from the PATINA study showing the addition of a CDK 4/6 inhibitor to standard therapy in patients with “double-positive” metastatic breast cancer significantly improved PFS. ➡️
bit.ly/4qMgJqJ
about 1 month ago
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Congrats to @danafarbernews.bsky.social’s Nicholas Polizzi, PhD, and Edward Boyden, PhD, of @mit.edu @hhmi-science.bsky.social who received a $1.3 million medical research grant from the W. M. Keck Foundation to fund single-molecule in situ protein sequencing via expansion microscopy.
bit.ly/4sRPFHY
about 1 month ago
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Congratulations to
@danafarbernews.bsky.social
’s Alice Shaw, MD, PhD, and Kimberly Stegmaier, MD, for being elected to the 2026 class of Fellows of the
@theaacr.bsky.social
Academy.
about 1 month ago
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Now in the @nytimes.com, @danafarbernews.bsky.social’s Dr. Kimmie Ng discusses diet and cancer risk, breaking down how what you eat affects your cancer risk. Read more here:
bit.ly/4t4nw0A
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These Foods Might Lower Cancer Risk
Decades of research suggests that your diet can influence the risk of various cancers. Here's what we know.
https://bit.ly/4t4nw0A
about 1 month ago
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New research in @natcancer.nature.com by @danafarbernews.bsky.social’s Robert Haddad, MD, demonstrates how intratumoral bacteria affect immune checkpoint blockade response within a randomized trial. These discoveries identify interactions that may guide future therapeutic strategies.
bit.ly/4a70tus
about 1 month ago
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The list is out! More than 145 @danafarbernews.bsky.social-affiliated faculty are recognized as 2026 Top Doctors by @bostonmagazine.bsky.social. Congratulations to all! Press release ➡️
bit.ly/4q1QN9y
about 1 month ago
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Could GLP-1 medications be a treatment pathway for some cancers? Novel research in Science Translational Medicine by @danafarbernews.bsky.social’s Erica Pimenta, MD, PhD, and Eli Van Allen, MD, uncovers promising targets that may lead to new targeted therapies for liposarcoma. ➡️
bit.ly/3LQfaJd
about 1 month ago
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New research in Angewandte Chemie by @danafarbernews.bsky.social’s Jun Qi, PhD, reveals a novel approach in achieving selective targeted protein degradation using proteosome directly in addition to the current PROTAC strategy, which could aid in developing therapies and cancer drugs.
bit.ly/4rbilu9
about 1 month ago
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Colorectal cancer is now the leading cause of cancer death in adults younger than 50, according to @americancancersoc.bsky.social researchers. @danafarbernews.bsky.social’s Dr. Jeff Meyerhardt tells @wsj.com that prevention & early detection are critical to reverse the alarming trend.
bit.ly/4sZzFUE
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Colorectal Cancer Is Now the Top Cause of Cancer Death in Younger People
Deaths from the disease are rising while U.S. cancer mortality overall is declining and 70% of Americans survive their cancers for at least five years.
https://bit.ly/4sZzFUE
about 1 month ago
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In @nejm.org, the ASCENT04 trial by @danafarbernews.bsky.social’s @stolaney1.bsky.social shows sacituzumab govitecan plus pembrolizumab as first-line therapy led durable responses and improved progression-free survival for pts w/advanced PD-L1 positive triple negative breast cancer.
bit.ly/4qASzj5
about 1 month ago
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Radioligand therapy in kidney cancer: Read in the SNMMI Journal about @danafarbernews.bsky.social's phase 2 LASER trial evaluating the safety and preliminary efficacy of Lu-PSMA-617 as systemic therapy for PSMA-positive clear cell renal cell carcinoma. ➡️
bit.ly/4qz1dOY
about 1 month ago
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Be sure to check out the latest episode of @UpstageLungCanc featuring Dr. David Barbie @danafarber, which explores whether a vaccine could change the future of #lungcancer. @DFarberThoracic Listen here:
bit.ly/45j1VqZ
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What if We Could Outsmart Lung Cancer?
Justin Gainor, MD Host: Hildy Grossman with Jordan Rich, co-host Guests: Justin Gainor, MD, Director of Targeted Immunotherapy at the Massachusetts General Hospital and David Barbie, MD, Director of the Barbie Lab at Dana Farber Cancer Institute Targeting Innate Immunity in Cancer Learn how this new era of evaluation and treatment is bringing tangible hope to those who need it most.
https://bit.ly/45j1VqZ
about 1 month ago
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“This rare cancer, liposarcoma, gives us a unique opportunity to study what GLP-1 drugs do to cancer cells,” @danafarbernews.bsky.social’s Dr. Erica Pimenta tells @washingtonpost.com about her research into whether the weight-loss medications could be a treatment pathway. ➡️
bit.ly/4k08KUr
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What science says about how weight-loss drugs affect cancer risk
Evidence is mounting that GLP-1 drugs may play a role in reducing cancer risk and deaths from certain cancers.
https://bit.ly/4k08KUr
about 1 month ago
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#Lungcancer stigma can be a barrier to care. @NarjustFlorez @DanaFarber spoke with the @nytimes about why addressing stigma matters for early detection and treatment. @dfarberthoracic Read ▶️
bit.ly
#Lungcancer
4bxXtIE
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Lung Cancer Stigma Keeps People From Care
The disease is the rare cancer met with accusations, not sympathy.
https://bit.ly/4bxXtIE
about 2 months ago
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A chance injury led to a #sarcoma diagnosis for 25-year-old Robbie. He found support at Dana-Farber Cancer Institute and forged a lasting relationship with his oncologist, Dr. Vinayak Venkataraman. Watch the video here:
youtu.be/cDo9JwKzN-w?...
#sarcoma
CC:
@danafarber.bsky.social
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A Sarcoma Story: From Treatment to Friendship | Dana-Farber Cancer Institute
A chance injury led to a sarcoma diagnosis for a 25-year-old patient. He found support at Dana-Farber Cancer Institute and forged a lasting relationship with his oncologist. Video published: 1/9/2026
https://youtu.be/cDo9JwKzN-w?si=al2BtNgkeHrhDrRf
about 2 months ago
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Register for the 2026 Transatlantic Exchange in Oncology Conference hosted in Boston 3/27 by @danafarbernews.bsky.social and @gustaveroussy.fr, co-chaired by Dr. Toni Choueiri. The theme of this year's one-day, hybrid event is Transatlantic Innovations in Cancer Drug Research. ➡️
bit.ly/4stedHf
about 2 months ago
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New research in @science.com from @danafarber.bsky.social @ckadoch.bsky.social and Siddhant Jain, PhD, answers a longstanding question regarding recruitment of chromatin regulatory machinery and provides a new framework for development of precision medicines in #cancer. Read more:
bit.ly/452dsec
about 2 months ago
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